{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:43:49Z","timestamp":1789155829278,"version":"build-2803163510"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Intracranial aneurysms, especially giant basilar artery aneurysms, pose significant diagnostic and therapeutic challenges due to their deep location and high rupture risk. During pregnancy, physiological changes such as increased blood volume and hormonal fluctuations further elevate the risk, making timely diagnosis and management critical to ensure maternal and fetal safety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We present a case of a 23-year-old woman at 28 weeks of gestation who reported severe occipital headache, vomiting, and photophobia. MRI revealed a 4.4 cm giant thrombosed right vertebral artery (V4 segment) aneurysm. Digital subtraction angiography confirmed the diagnosis. To minimize fetal risk, definitive endovascular intervention was deferred until two months postpartum. She was closely monitored throughout pregnancy and delivered without complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Two months postpartum, cerebral angiography showed aneurysmal progression, and endovascular coiling with segment sacrifice was successfully performed. Follow-up CT at three months demonstrated aneurysm reduction to 2.8 cm and progressive calcification, suggesting chronic stabilization. The patient's neurological symptoms resolved, with no new deficits. Dual antiplatelet therapy was initiated post-procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case highlights the importance of a multidisciplinary approach and tailored management in pregnant patient with cerebral aneurysms. Delaying intervention until postpartum may be safe and effective when clinical stability allows, reinforcing the role of individualized care strategies in optimizing maternal and fetal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111802","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T23:34:52Z","timestamp":1755128092000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Delayed intervention for a giant thrombosed vertebral artery aneurysm in pregnancy: A case report"],"prefix":"10.1097","volume":"134","author":[{"given":"Jehad","family":"Khamaysa","sequence":"first","affiliation":[{"name":"Department of Radiology, Tubas Turkish Governmental Hospital, Tubas, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jawad","family":"Ziyadeh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, An-Najah National University Hospital, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula Abu","family":"Nahla","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hebron University, Hebron, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Imad Eddin","family":"Taha","sequence":"additional","affiliation":[{"name":"Department of Medicine, An Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mais","family":"Masoud","sequence":"additional","affiliation":[{"name":"Department of Medicine, An Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjad","family":"Shaar","sequence":"additional","affiliation":[{"name":"Department of Medicine, An Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"12","key":"R1-118-20260310","article-title":"A case report of a giant basilar artery aneurysm","volume":"15","author":"Alharbi","year":"2023","journal-title":"Cureus"},{"key":"R2-118-20260310","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.2-112.v1","article-title":"Giant aneurysm of the basilar artery in an 86 year old woman","volume":"2","author":"Yu","year":"2013","journal-title":"F1000Res"},{"key":"R3-118-20260310","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2017.9.JNS171191","article-title":"Detection rates and sites of unruptured intracranial aneurysms according to sex and age: an analysis of MR angiography-based brain examinations of 4070 healthy Japanese adults","author":"Imaizumi","year":"2018","journal-title":"J. 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