{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T07:55:29Z","timestamp":1773215729023,"version":"3.50.1"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>\n                      Extensive hepatopulmonary hydatidosis is a rare and challenging manifestation of\n                      <jats:italic toggle=\"yes\">Echinococcus granulosus<\/jats:italic>\n                      infection in pediatric patients. It can lead to significant morbidity if not promptly recognized and appropriately managed. Early diagnosis and a staged multidisciplinary approach are essential to achieve favorable outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>An 8-year-old boy presented with weight loss, cough, and hepatomegaly. Imaging revealed over 35 hydatid cysts in the liver and both lungs. He underwent staged bilateral lung cyst excision using hybrid minimally invasive surgery, followed by PAIR procedures for liver cysts and albendazole therapy. Postoperative recovery was uneventful, with full resolution of lung cysts and significant reduction in hepatic cyst burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Extensive multi-organ hydatidosis in children is rare. Management depends on cyst location, number, and complications. Minimally invasive surgery combined with medical therapy is effective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case highlights the importance of timely diagnosis and staged multidisciplinary management in pediatric multiorgan hydatidosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111807","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T06:45:48Z","timestamp":1755153948000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Successful management of a rare extensive hepatopulmonary hydatidosis with over 35 cysts: A case report and literature review"],"prefix":"10.1097","volume":"134","author":[{"given":"Salahaldeen","family":"Deeb","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Al-Quds University, Jerusalem, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Sayyedahmad","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Al-Quds University, Jerusalem, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaid","family":"Sharif","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Alexandria University, Alexandria, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sireen","family":"Manasrah","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Al-Quds University, Jerusalem, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hussein","family":"Abusharkh","sequence":"additional","affiliation":[{"name":"Radiology department, Al Ahli Hospital, Hebron, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousef","family":"Abuasbeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"3","key":"R2-120-20260310","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/S0891-5520(20)30545-6","article-title":"Echinococcal disease","volume":"7","author":"Kammerer","year":"1993","journal-title":"Infect. Dis. Clin. N. Am"},{"key":"R3-120-20260310","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/8859116","article-title":"Review on epidemiology and public health significance of hydatidosis","volume":"2020","author":"Gessese","year":"2020","journal-title":"Vet. Med. Int"},{"issue":"6","key":"R5-120-20260310","doi-asserted-by":"crossref","first-page":"764","DOI":"10.9738\/INTSURG-D-14-00069.1","article-title":"Open surgery for hepatic hydatid disease","volume":"99","author":"Sozuer","year":"2014","journal-title":"Int. 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Case Rep"},{"issue":"3","key":"R10-120-20260310","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1067\/mtc.2002.119341","article-title":"Pleural complications of hydatid disease","volume":"123","author":"Aribas","year":"2002","journal-title":"J. Thorac. Cardiovasc. Surg"},{"issue":"6","key":"R11-120-20260310","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1002\/ccr3.2763","article-title":"Massive hydatid cysts in the lung and liver of a 4-year-old boy","volume":"8","author":"Yu","year":"2020","journal-title":"Clin. Case Rep"},{"issue":"20","key":"R12-120-20260310","doi-asserted-by":"crossref","first-page":"128","DOI":"10.9734\/jammr\/2023\/v35i205182","article-title":"Concurrent right lung and liver hydatidosis: an uncommon presentation - managed by one-stage surgery","volume":"35","author":"Jain","year":"2023","journal-title":"J. Adv. Med. Med. Res"},{"issue":"1","key":"R13-120-20260310","doi-asserted-by":"crossref","first-page":"40","DOI":"10.4103\/0189-6725.59362","article-title":"Minimal access surgery for multiorgan hydatid cysts","volume":"7","author":"Mishra","year":"2010","journal-title":"Afr. J. Paediatr. Surg"},{"key":"R14-120-20260310","doi-asserted-by":"crossref","first-page":"953","DOI":"10.12659\/AJCR.904432","article-title":"Treatment of hepatic hydatid cyst in a 7-year-old boy using a new type of radiofrequency ablation electrode","volume":"18","author":"Botsa","year":"2017","journal-title":"Am. J. Case Rep"},{"issue":"1","key":"R15-120-20260310","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1186\/1752-1947-4-205","article-title":"Hepatopulmonary hydatidosis in a ten-year-old girl: a case report","volume":"4","author":"Anyfantakis","year":"2010","journal-title":"J. Med. 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