{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T04:51:22Z","timestamp":1780635082645,"version":"3.54.1"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"publisher","award":["8157 0607"],"award-info":[{"award-number":["8157 0607"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Surgery"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.ijsu.2018.02.045","type":"journal-article","created":{"date-parts":[[2018,2,28]],"date-time":"2018-02-28T04:16:20Z","timestamp":1519791380000},"page":"248-257","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"C","title":["Maintenance versus non-maintenance intravesical Bacillus Calmette-Guerin instillation for non-muscle invasive bladder cancer: A systematic review and meta-analysis of randomized clinical trials"],"prefix":"10.1097","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5150-7536","authenticated-orcid":false,"given":"Siteng","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialiang","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5538-4310","authenticated-orcid":false,"given":"Xiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"3","key":"10.1016\/j.ijsu.2018.02.045_bib1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.eururo.2016.05.041","article-title":"EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2016","volume":"71","author":"Babjuk","year":"2017","journal-title":"Eur. Urol."},{"issue":"3","key":"10.1016\/j.ijsu.2018.02.045_bib2","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.juro.2017.04.086","article-title":"Treatment of non-metastatic muscle-invasive bladder cancer: AUA\/ASCO\/ASTRO\/SUO guideline","volume":"198","author":"Chang","year":"2017","journal-title":"J. Urol."},{"key":"10.1016\/j.ijsu.2018.02.045_bib3","unstructured":"NCCN Clinical Practice Guidelines in Oncology-Bladder Cancer(2017 Version 5)[DB\/OL]."},{"issue":"5","key":"10.1016\/j.ijsu.2018.02.045_bib4","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.eururo.2008.06.062","article-title":"Is maintenance Bacillus Calmette-Gu\u00e9rin really necessary?","volume":"54","author":"Herr","year":"2008","journal-title":"Eur. Urol."},{"issue":"2","key":"10.1016\/j.ijsu.2018.02.045_bib5","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.eururo.2015.02.040","article-title":"Maintenance therapy with 3-monthly Bacillus calmette-guerin for 3 Years is not superior to standard induction therapy in high-risk non-muscle-invasive urothelial bladder carcinoma: final results of randomised CUETO study 98013","volume":"68","author":"Martinez-Pineiro","year":"2015","journal-title":"Eur. Urol."},{"issue":"4","key":"10.1016\/j.ijsu.2018.02.045_bib6","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.eururo.2013.05.027","article-title":"Maintenance bacillus Calmette-Gu\u00e9rin treatment of non-muscle-invasive bladder cancer: a critical evaluation of the evidence","volume":"64","author":"Ehdaie","year":"2013","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ijsu.2018.02.045_bib7","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.ijsu.2018.02.045_bib8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/bjc.1974.119","article-title":"The TNM classification of malignant tumours","volume":"30","author":"Easson","year":"1974","journal-title":"Br. J. Canc."},{"key":"10.1016\/j.ijsu.2018.02.045_bib9","series-title":"Histological Typing of Urinary Bladder Tumours","author":"Mostofi","year":"1973"},{"key":"10.1016\/j.ijsu.2018.02.045_bib10","series-title":"Histological Typing of Urinary Bladder Tumours","first-page":"358","author":"Mostofi","year":"1999"},{"issue":"1","key":"10.1016\/j.ijsu.2018.02.045_bib11","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1745-6215-8-16","article-title":"Practical methods for incorporating summary time-to-event data into meta-analysis","volume":"8","author":"Tierney","year":"2007","journal-title":"Trials"},{"issue":"7414","key":"10.1016\/j.ijsu.2018.02.045_bib12","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"Br. Med. J."},{"issue":"oct18 2","key":"10.1016\/j.ijsu.2018.02.045_bib13","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"issue":"7109","key":"10.1016\/j.ijsu.2018.02.045_bib14","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.ijsu.2018.02.045_bib15","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50","author":"Begg","year":"1994","journal-title":"Biometrics"},{"issue":"12","key":"10.1016\/j.ijsu.2018.02.045_bib16","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1016\/j.jclinepi.2011.01.012","article-title":"GRADE guidelines 6. Rating the quality of evidence\u2013impreCIion","volume":"64","author":"Guyatt","year":"2011","journal-title":"J. Clin. Epidemiol."},{"issue":"12","key":"10.1016\/j.ijsu.2018.02.045_bib17","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/j.jclinepi.2011.04.014","article-title":"GRADE guidelines: 8. Rating the quality of evidence\u2013indirectness","volume":"64","author":"Guyatt","year":"2011","journal-title":"J. Clin. Epidemiol."},{"issue":"12","key":"10.1016\/j.ijsu.2018.02.045_bib18","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.jclinepi.2011.03.017","article-title":"GRADE guidelines: 7. Rating the quality of evidence\u2013inconsistency","volume":"64","author":"Guyatt","year":"2011","journal-title":"J. Clin. Epidemiol."},{"issue":"12","key":"10.1016\/j.ijsu.2018.02.045_bib19","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.jclinepi.2011.01.011","article-title":"GRADE guidelines: 5. Rating the quality of evidence\u2013publication bias","volume":"64","author":"Guyatt","year":"2011","journal-title":"J. Clin. Epidemiol."},{"issue":"12","key":"10.1016\/j.ijsu.2018.02.045_bib20","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jclinepi.2010.07.017","article-title":"GRADE guidelines: 4. Rating the quality of evidence\u2014study limitations (risk of bias)","volume":"64","author":"Guyatt","year":"2011","journal-title":"J. Clin. Epidemiol."},{"issue":"2","key":"10.1016\/j.ijsu.2018.02.045_bib21","doi-asserted-by":"crossref","first-page":"290","DOI":"10.5980\/jpnjurol1989.82.290","article-title":"Intravesical instillation of bacillus Calmette-Guerin for superficial bladder carcinoma: study on significance of additional maintenance instillations of bacillus Calmette-Guerin","volume":"82","author":"Yabusaki","year":"1991","journal-title":"Jpn. J. Urol."},{"issue":"9","key":"10.1016\/j.ijsu.2018.02.045_bib22","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/j.1442-2042.2010.02584.x","article-title":"Maintenance intravesical bacillus Calmette-Guerin instillation for Ta, T1 cancer and carcinoma in situ of the bladder: randomized controlled trial by the BCG Tokyo Strain Study Group","volume":"17","author":"Koga","year":"2010","journal-title":"Int. J. Urol."},{"issue":"2","key":"10.1016\/j.ijsu.2018.02.045_bib23","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1464-410X.2010.09891.x","article-title":"Maintenance therapy with bacillus Calmette-Guerin Connaught strain clearly prolongs recurrence-free survival following transurethral resection of bladder tumour for non-muscle-invasive bladder cancer","volume":"108","author":"Hinotsu","year":"2011","journal-title":"BJU Int."},{"issue":"4","key":"10.1016\/j.ijsu.2018.02.045_bib24","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/S0022-5347(05)67707-5","article-title":"Maintenance bacillus Calmette-Guerin immunotherapy for recurrent TA, T1 and carcinoma in situ transitional cell carcinoma of the bladder: a randomized Southwest Oncology Group Study","volume":"163","author":"Lamm","year":"2000","journal-title":"J. Urol."},{"issue":"10","key":"10.1016\/j.ijsu.2018.02.045_bib25","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1111\/iju.13167","article-title":"Insignificant role of bacillus Calmette\u2013Gu\u00e9rin maintenance therapy after complete transurethral resection of bladder tumor for intermediate- and high-risk non-muscle-invasive bladder cancer: results from a randomized trial","volume":"23","author":"Nakai","year":"2016","journal-title":"Int. J. Urol."},{"issue":"5","key":"10.1016\/j.ijsu.2018.02.045_bib26","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1016\/S0022-5347(05)66333-1","article-title":"Control group and maintenance treatment with bacillus Calmette-Guerin for carcinoma in situ and\/or high grade bladder tumors","volume":"165","author":"Palou","year":"2001","journal-title":"J. Urol."},{"issue":"3","key":"10.1016\/j.ijsu.2018.02.045_bib27","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1200\/JCO.1987.5.3.441","article-title":"A prospective randomized trial of maintenance versus nonmaintenance intravesical bacillus Calmette-Guerin therapy of superficial bladder cancer","volume":"5","author":"Badalament","year":"1987","journal-title":"J. Clin. Oncol."},{"issue":"2","key":"10.1016\/j.ijsu.2018.02.045_bib28","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0022-5347(17)43125-9","article-title":"Single course versus maintenance bacillus Calmette-Guerin therapy for superficial bladder tumors: a prospective, randomized trial","volume":"138","author":"Hudson","year":"1987","journal-title":"J. Urol."},{"issue":"2","key":"10.1016\/j.ijsu.2018.02.045_bib29","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/1097-0142(19950115)75:2<552::AID-CNCR2820750219>3.0.CO;2-H","article-title":"Bacillus Calmette-Guerin treatment of existing papillary bladder cancer and carcinoma in situ of the bladder. Four-year results. The Bladder Cancer BCG Study Group","volume":"75","author":"Akaza","year":"1995","journal-title":"Cancer"},{"issue":"5","key":"10.1016\/j.ijsu.2018.02.045_bib30","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1016\/S0022-5347(05)64273-5","article-title":"Intravesical bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: a meta-analysis of the published results of randomized clinical trials","volume":"168","author":"Sylvester","year":"2002","journal-title":"J. Urol."},{"issue":"4","key":"10.1016\/j.ijsu.2018.02.045_bib31","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.urology.2003.11.049","article-title":"Intravesical bacille Calmette-Guerin versus mitomycin C in superficial bladder cancer: formal meta-analysis of comparative studies on tumor progression","volume":"63","author":"Bohle","year":"2004","journal-title":"Urology"},{"issue":"1","key":"10.1016\/j.ijsu.2018.02.045_bib32","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0895-4356(94)00106-Z","article-title":"Cumulative meta-analysis of clinical trials builds evidence for exemplary medical care","volume":"48","author":"Lau","year":"1995","journal-title":"J. Clin. Epidemiol."},{"issue":"7","key":"10.1016\/j.ijsu.2018.02.045_bib33","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/j.1464-410X.2003.04764.x","article-title":"Bacillus Calmette-Guerin therapy in stage Ta\/T1 bladder cancer: prognostic factors for time to recurrence and progression","volume":"93","author":"Andius","year":"2015","journal-title":"BJU Int."},{"issue":"3","key":"10.1016\/j.ijsu.2018.02.045_bib34","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.eururo.2012.10.039","article-title":"Final results of an EORTC-GU cancers group randomized study of maintenance bacillus Calmette-Gu\u00e9rin in intermediate- and high-risk Ta, T1 papillary carcinoma of the urinary bladder: one-third dose versus full dose and 1 year versus 3 years of maintenance","volume":"63","author":"Oddens","year":"2013","journal-title":"Eur. Urol."},{"issue":"5","key":"10.1016\/j.ijsu.2018.02.045_bib35","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.eururo.2009.12.024","volume":"57","author":"Sylvester","year":"2010","journal-title":"Eur. Urol."}],"container-title":["International Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1743919118305764?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1743919118305764?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T16:04:08Z","timestamp":1677081848000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1743919118305764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":35,"alternative-id":["S1743919118305764"],"URL":"https:\/\/doi.org\/10.1016\/j.ijsu.2018.02.045","relation":{},"ISSN":["1743-9191"],"issn-type":[{"value":"1743-9191","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maintenance versus non-maintenance intravesical Bacillus Calmette-Guerin instillation for non-muscle invasive bladder cancer: A systematic review and meta-analysis of randomized clinical trials","name":"articletitle","label":"Article Title"},{"value":"International Journal of Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijsu.2018.02.045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 IJS Publishing Group Ltd. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}