{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T21:24:44Z","timestamp":1779139484584,"version":"3.51.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian Journal of Tuberculosis"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.ijtb.2018.07.006","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T13:15:28Z","timestamp":1533820528000},"page":"322-328","source":"Crossref","is-referenced-by-count":8,"title":["Time to sputum culture conversion and treatment outcome among the first cohort of multidrug resistant tuberculosis patients in a high burden country"],"prefix":"10.1016","volume":"65","author":[{"given":"O.M.","family":"Ige","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina E.","family":"Oladokun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijtb.2018.07.006_bib1","unstructured":"World Health Organization. Multidrug and extensively drug resistant TB (M\/XDR-TB): 2014 global report. http:\/\/www.who.int\/tb\/publications\/global_report\/en\/. Accessed 12 November 2014."},{"key":"10.1016\/j.ijtb.2018.07.006_bib2","series-title":"National Drug Resistance TB Prevalence Survey Report","author":"Federal Ministry of Health, Nigeria","year":"2012"},{"issue":"suppl","key":"10.1016\/j.ijtb.2018.07.006_bib3","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1086\/518665","article-title":"HIV Infection and multidrug-resistant tuberculosis \u2013 the perfect storm","volume":"196","author":"Wells","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib4","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/1471-2334-13-137","article-title":"Prevalence of multidrug resistance in Mycobacterium tuberculosis isolates from HIV seropositive and seronegative patients with pulmonary tuberculosis in north India","volume":"13","author":"Sethi","year":"2013","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib5","series-title":"National Tuberculosis and Leprosy Control Programme","author":"Federal Ministry of Health, Nigeria","year":"2010"},{"key":"10.1016\/j.ijtb.2018.07.006_bib6","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1183\/09031936.00073611","article-title":"WHO guidelines for the programmatic management of drug-resistant tuberculosis: 2011 update","volume":"38","author":"Falzon","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ijtb.2018.07.006_bib7","series-title":"Guidelines for the Clinical Management and Control of Drug Resistant Tuberculosis","first-page":"34","year":"2011"},{"key":"10.1016\/j.ijtb.2018.07.006_bib8","series-title":"Guidelines for Establishing DOTS-plus Pilot Projects for the Management of Multidrug-resistant Tuberculosis (MDR-TB)","author":"World Health Organization","year":"2000"},{"key":"10.1016\/j.ijtb.2018.07.006_bib9","doi-asserted-by":"crossref","first-page":"650","DOI":"10.7326\/0003-4819-144-9-200605020-00008","article-title":"Time to sputum culture conversion in multidrug-resistant tuberculosis and relationship to treatment outcome","volume":"144","author":"Holtz","year":"2006","journal-title":"Ann Intern Med"},{"issue":"3","key":"10.1016\/j.ijtb.2018.07.006_bib10","doi-asserted-by":"crossref","first-page":"348","DOI":"10.5588\/ijtld.12.0100","article-title":"Impact of the human immunodeficiency virus on early multidrug-resistant tuberculosis treatment outcomes in Botswana","volume":"17","author":"Hafkin","year":"2013","journal-title":"Int J Tuberc Lung Dis"},{"issue":"1","key":"10.1016\/j.ijtb.2018.07.006_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0015841","article-title":"Culture conversion among HIV co-infected multidrug-resistant tuberculosis patients in Tugela Ferry, South Africa","volume":"6","author":"Brust","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.ijtb.2018.07.006_bib12","first-page":"877","article-title":"Outcome of chemotherapy in 107 patients with pulmonary tuberculosis resistant to isoniazid and rifampin","volume":"2","author":"Park","year":"1998","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib13","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0140-6736(05)70196-3","article-title":"Clinical outcome of individualised treatment of multidrug-resistant tuberculosis in Latvia: a retrospective cohort study","volume":"365","author":"Leimane","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.ijtb.2018.07.006_bib14","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1164\/rccm.200308-1159OC","article-title":"Treatment and outcome analysis of 205 patients with multidrug-resistant tuberculosis","volume":"169","author":"Chan","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ijtb.2018.07.006_bib15","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1056\/NEJM200107193450303","article-title":"The treatment of multidrug-resistant tuberculosis in Turkey","volume":"345","author":"Tahao\u011flu","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijtb.2018.07.006_bib16","doi-asserted-by":"crossref","first-page":"650","DOI":"10.7326\/0003-4819-144-9-200605020-00008","article-title":"Time to sputum culture conversion in multidrug-resistant tuberculosis: predictors and relationship to treatment outcome","volume":"144","author":"Holtz","year":"2006","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ijtb.2018.07.006_bib17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1473-3099(09)70041-6","article-title":"Treatment outcome among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis","volume":"9","author":"Orenstein","year":"2009","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib18","first-page":"529","article-title":"Outcome of standardized treatment for patients with MDR-TB from Tamil Nadu, India","volume":"133","author":"Joseph","year":"2011","journal-title":"Indian J Med Res"},{"issue":"10","key":"10.1016\/j.ijtb.2018.07.006_bib19","first-page":"694","article-title":"Treatment outcome of multi-drug resistant tuberculosis in a tertiary care hospital in Karachi","volume":"59","author":"Rao","year":"2009","journal-title":"J Pak Med Assoc"},{"key":"10.1016\/j.ijtb.2018.07.006_bib20","first-page":"361","article-title":"Self-administered standardized regimens for multi drug resistant tuberculosis in South Korea","volume":"8","author":"Park","year":"2004","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib21","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1183\/09031936.06.00125705","article-title":"Outcome of pulmonary multidrug- resistant tuberculosis: a 6-year follow-up study","volume":"28","author":"Ching","year":"2006","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ijtb.2018.07.006_bib22","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1016\/S0140-6736(02)08830-X","article-title":"Feasibility and cost-effectiveness of standardized second- line drug treatment for chronic tuberculosis patients: a national cohort study in Peru","volume":"359","author":"Sua'rez","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.ijtb.2018.07.006_bib23","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1086\/318489","article-title":"Clinical outcomes of Estonian patients with primary multidrug resistant versus drug-susceptible tuberculosis","volume":"32","author":"Lockman","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib24","first-page":"1129","article-title":"Ambulatory treatment of multidrug resistant pulmonary tuberculosis patients at a chest clinic","volume":"5","author":"Kim","year":"2001","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib25","first-page":"35","article-title":"Long term treatment outcome in multi drug resistant tuberculosis (MDR-TB)","volume":"126 836S","author":"Prasad","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.ijtb.2018.07.006_bib26","first-page":"976","article-title":"Seven-year DOTS-Plus pilot experience in India: results, constraints and issues","volume":"13","author":"Singla","year":"2009","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib27","first-page":"156","article-title":"Management of multidrug-resistant tuberculosis: a survival guide for physicians and pediatricians","volume":"3","author":"Schaaf","year":"2011","journal-title":"Public Health Action"},{"issue":"9","key":"10.1016\/j.ijtb.2018.07.006_bib28","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.5588\/ijtld.10.0781","article-title":"Household contact investigation of multidrug-resistant and extensively drug-resistant tuberculosis in a high HIV prevalence setting","volume":"15","author":"Vella","year":"2011","journal-title":"Int J Tuberc Lung Dis"},{"issue":"9","key":"10.1016\/j.ijtb.2018.07.006_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0006914","article-title":"Treatment outcomes of multidrug-resistant tuberculosis: a systematic review and meta-Analysis","volume":"4","author":"Johnston","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.ijtb.2018.07.006_bib30","article-title":"Ambulatory multi-drug resistant tuberculosis treatment outcomes in a cohort of HIV-infected patients in a slum setting in Mumbai, India","volume":"12","author":"Isaakidis","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.ijtb.2018.07.006_bib31","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.5588\/ijtld.14.0100","article-title":"Successful \u20189-month Bangladesh regimen\u2019 for multidrug-resistant tuberculosis among over 500 consecutive patients","volume":"18","author":"Aung","year":"2014","journal-title":"Int J Tuberc Lung Dis"},{"issue":"10","key":"10.1016\/j.ijtb.2018.07.006_bib32","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.5588\/ijtld.13.0075","article-title":"High cure rate with standardised short-course multidrug-resistant tuberculosis treatment in Niger: no relapses","volume":"18","author":"Piubello","year":"2014","journal-title":"Int J Tuberc Lung Dis"},{"issue":"5","key":"10.1016\/j.ijtb.2018.07.006_bib33","doi-asserted-by":"crossref","first-page":"517","DOI":"10.5588\/ijtld.14.0535","article-title":"High effectiveness of a 12-month regimen for MDR-TB patients in Cameron","volume":"19","author":"Kuaban","year":"2015","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.ijtb.2018.07.006_bib34","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/1745-6215-15-353","article-title":"Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial","volume":"15","author":"Nunn","year":"2014","journal-title":"Trials"},{"key":"10.1016\/j.ijtb.2018.07.006_bib35","unstructured":"WHO treatment guidelines for drug-resistant tuberculosis, 2016 update. http:\/\/apps.who.int\/iris\/handle\/10665\/250125\/."},{"key":"10.1016\/j.ijtb.2018.07.006_bib36","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ijid.2016.10.021","article-title":"Applicability of the shorter \u2018Bangladesh regimen\u2019 in high multidrug-resistant tuberculosis settings","volume":"56","author":"Sotgiu","year":"2017","journal-title":"Int J Infect Dis"}],"container-title":["Indian Journal of Tuberculosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019570718301768?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019570718301768?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T16:34:46Z","timestamp":1543854886000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0019570718301768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0019570718301768"],"URL":"https:\/\/doi.org\/10.1016\/j.ijtb.2018.07.006","relation":{},"ISSN":["0019-5707"],"issn-type":[{"value":"0019-5707","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}