{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T15:11:11Z","timestamp":1769613071339,"version":"3.49.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Journal of Tuberculosis"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.ijtb.2025.06.014","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T19:51:47Z","timestamp":1750276307000},"page":"S161-S167","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"S2","title":["Nanoparticle-based biosensor- from existing to advanced tools in diagnosis of tuberculosis"],"prefix":"10.1016","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2674-9146","authenticated-orcid":false,"given":"Karthikeyan","family":"Sundaram","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sathyapriya","family":"Subramani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkataraman","family":"Prabhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijtb.2025.06.014_bib1","series-title":"Global Tuberculosis Report 2024","year":"2024"},{"key":"10.1016\/j.ijtb.2025.06.014_bib2","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-05453-3","article-title":"Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles","volume":"7","author":"Costa-Gouveia","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijtb.2025.06.014_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2021.339037","article-title":"Catalytic ferromagnetic gold nanoparticle immunoassay for the detection and differentiation of Mycobacterium tuberculosis and Mycobacterium bovis","volume":"1184","author":"Gilbride","year":"2021","journal-title":"Anal Chim Acta"},{"key":"10.1016\/j.ijtb.2025.06.014_bib4","doi-asserted-by":"crossref","first-page":"8548","DOI":"10.1039\/D4RA00420E","article-title":"Surface-enhanced Raman spectroscopy for characterization of filtrates of blood serum samples from patients with tuberculosis obtained by 50 kDa filtration devices","volume":"14","author":"Kamran","year":"2024","journal-title":"RSC Adv"},{"key":"10.1016\/j.ijtb.2025.06.014_bib5","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-38740-3","article-title":"Diagnosis of genitourinary tuberculosis: detection of mycobacterial lipoarabinomannan and MPT-64 biomarkers within urine extracellular vesicles by nano-based immuno-PCR assay","volume":"13","author":"Kamra","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijtb.2025.06.014_bib6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jcis.2014.07.014","article-title":"Self-assembled monolayers of mercaptobenzoic acid and magnetite nanoparticles as an efficient support for development of tuberculosis genosensor","volume":"433","author":"Costa","year":"2014","journal-title":"J Colloid Interface Sci"},{"key":"10.1016\/j.ijtb.2025.06.014_bib7","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-85039-2","article-title":"Laser-scribed graphene nanofiber decorated with oil palm lignin capped silver nanoparticles: a green biosensor","volume":"11","author":"Tai","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijtb.2025.06.014_bib8","doi-asserted-by":"crossref","DOI":"10.1186\/s12866-021-02328-6","article-title":"Two target genes based multiple cross displacement amplification combined with a lateral flow biosensor for the detection of Mycobacterium tuberculosis complex","volume":"21","author":"Huang","year":"2021","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.ijtb.2025.06.014_bib9","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3390\/ph16040581","article-title":"An insight into advances in developing nanotechnology based therapeutics, drug delivery, diagnostics and vaccines: multidimensional applications in tuberculosis disease management","volume":"16","author":"Chopra","year":"2023","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.ijtb.2025.06.014_bib10","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.3390\/s18061932","article-title":"Immuno nanosensor for the ultrasensitive naked eye detection of tuberculosis","volume":"18","author":"Bakhori","year":"2018","journal-title":"Sensors"},{"key":"10.1016\/j.ijtb.2025.06.014_bib11","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1373\/clinchem.2017.273698","article-title":"Clinical evaluation of a blood assay to diagnose paucibacillary tuberculosis via bacterial antigens","volume":"64","author":"Liu","year":"2018","journal-title":"Clin Chem"},{"key":"10.1016\/j.ijtb.2025.06.014_bib12","doi-asserted-by":"crossref","first-page":"4303","DOI":"10.2147\/IJN.S163925","article-title":"Antimycobacterial susceptibility evaluation of rifampicin and isoniazid benz-hydrazone in biodegradable polymeric nanoparticles against Mycobacterium tuberculosis H37Rv strain","volume":"13","author":"Hakkimane","year":"2018","journal-title":"Int J Nanomed"},{"key":"10.1016\/j.ijtb.2025.06.014_bib13","doi-asserted-by":"crossref","first-page":"3689","DOI":"10.2147\/IJN.S159839","article-title":"Development of a thermostable nanoemulsion adjuvanted vaccine against tuberculosis using a design-of-experiments approach","volume":"13","author":"Kramer","year":"2018","journal-title":"Int J Nanomed"},{"key":"10.1016\/j.ijtb.2025.06.014_bib14","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3390\/ph16040581","article-title":"An insight into advances in developing nanotechnology based therapeutics, drug delivery, diagnostics and vaccines: multidimensional applications in tuberculosis disease management","volume":"16","author":"Chopra","year":"2023","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.ijtb.2025.06.014_bib15","doi-asserted-by":"crossref","first-page":"3983","DOI":"10.2147\/IJN.S255398","article-title":"Biosynthesis of copper oxide nanoparticles with potential biomedical applications","volume":"15","author":"Rabiee","year":"2020","journal-title":"Int J Nanomed"},{"issue":"2","key":"10.1016\/j.ijtb.2025.06.014_bib16","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s00408-018-00194-0","article-title":"Nanogold assay improves accuracy of conventional TB diagnostics","volume":"197","author":"El-Samadony","year":"2019","journal-title":"Lung"},{"key":"10.1016\/j.ijtb.2025.06.014_bib17","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bioelechem.2012.04.003","article-title":"Development of an electrochemical DNA biosensor with the DNA immobilization based on in situ generation of dithiocarbamate ligands","volume":"88","author":"Wang","year":"2012","journal-title":"Bioelectrochemistry"},{"issue":"9","key":"10.1016\/j.ijtb.2025.06.014_bib18","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1021\/acssensors.7b00450","article-title":"Diagnosis of tuberculosis using colorimetric gold nanoparticles on a paper-based analytical device","volume":"2","author":"Tt","year":"2017","journal-title":"ACS Sens"},{"key":"10.1016\/j.ijtb.2025.06.014_bib19","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-015-0109-1","article-title":"One nanoprobe, two pathogens: gold nanoprobes multiplexing for point-of-care","volume":"13","author":"Veigas","year":"2015","journal-title":"J Nanobiotechnol"},{"key":"10.1016\/j.ijtb.2025.06.014_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2022.1046930","article-title":"Tuberculosis detection from raw sputum samples using Au-electroplated screen-printed electrodes as E-DNA sensor","volume":"10","author":"Sharif","year":"2022","journal-title":"Front Chem"},{"issue":"7-8","key":"10.1016\/j.ijtb.2025.06.014_bib21","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.clinbiochem.2012.12.020","article-title":"Unmodified gold nanoparticles for direct and rapid detection of Mycobacterium tuberculosis complex","volume":"46","author":"Hussain","year":"2013","journal-title":"Clin Biochem"},{"issue":"6","key":"10.1016\/j.ijtb.2025.06.014_bib22","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.bjid.2014.05.015","article-title":"Development of sandwich-form biosensor to detect Mycobacterium tuberculosis complex in clinical sputum specimens","volume":"18","author":"Shojaei","year":"2014","journal-title":"Braz J Infect Dis"},{"key":"10.1016\/j.ijtb.2025.06.014_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2022.103145","article-title":"Surface-enhanced Raman spectroscopy for the characterization of pellets of biofilm forming bacterial strains of Staphylococcus epidermidis","volume":"40","author":"Shakeel","year":"2022","journal-title":"Photodiagnosis Photodyn Ther"},{"key":"10.1016\/j.ijtb.2025.06.014_bib24","article-title":"Spotlight on mycobacterial lipid exploitation using nanotechnology for diagnosis, vaccines, and treatments","volume":"48","author":"Valdemar-Aguilar","year":"2023","journal-title":"Nanomedicine"},{"key":"10.1016\/j.ijtb.2025.06.014_bib25","doi-asserted-by":"crossref","first-page":"7919","DOI":"10.1038\/s41598-022-12018-6","article-title":"Non-volatile organic compounds in exhaled breath particles correspond to active tuberculosis","volume":"12","author":"Chen","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijtb.2025.06.014_bib26","doi-asserted-by":"crossref","first-page":"7751","DOI":"10.1038\/s41467-022-35453-5","article-title":"A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis detection","volume":"13","author":"Mosquera-Restrepo","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.ijtb.2025.06.014_bib27","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/jcm9010111","article-title":"Point-of-care urine LAM tests for tuberculosis diagnosis: a status update","volume":"9","author":"Bulterys","year":"2019","journal-title":"J Clin Med"},{"issue":"3","key":"10.1016\/j.ijtb.2025.06.014_bib28","doi-asserted-by":"crossref","first-page":"568","DOI":"10.3390\/nano10030568","article-title":"In vivo biodistribution of respirable solid lipid nanoparticles surface-decorated with a mannose-based surfactant: a promising tool for pulmonary tuberculosis treatment","volume":"10","author":"Truzzi","year":"2020","journal-title":"Nanomaterials (Basel)"},{"key":"10.1016\/j.ijtb.2025.06.014_bib29","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1002\/jbio.201500271","article-title":"In vivo autofluorescence in the biological windows: the role of pigmentation","volume":"9","author":"Del","year":"2016","journal-title":"J. Biophotonics."},{"key":"10.1016\/j.ijtb.2025.06.014_bib30","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3390\/bios8040128","article-title":"Magnetic nanoparticle-based biosensing assay quantitatively enhances acid-fast bacilli count in paucibacillary pulmonary tuberculosis","volume":"8","author":"Gordillo-Marroqu\u00edn","year":"2018","journal-title":"Biosensors"},{"key":"10.1016\/j.ijtb.2025.06.014_bib31","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3390\/diagnostics9040222","article-title":"Nanoparticle-based biosensing assay for universally accessible low-cost TB detection with comparable sensitivity as culture","volume":"9","author":"Briceno","year":"2019","journal-title":"Diagnostics"},{"key":"10.1016\/j.ijtb.2025.06.014_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/bios9010001","article-title":"Nanoparticle-based biosensing of tuberculosis, an affordable and practical alternative to current methods","volume":"9","author":"Bhusal","year":"2018","journal-title":"Biosensors"},{"key":"10.1016\/j.ijtb.2025.06.014_bib33","doi-asserted-by":"crossref","first-page":"10087","DOI":"10.1039\/C6NR00484A","article-title":"A nucleic acid strand displacement system for the multiplexed detection of tuberculosis-specific mRNA using quantum dots","volume":"8","author":"Gliddon","year":"2016","journal-title":"Nanoscale"},{"key":"10.1016\/j.ijtb.2025.06.014_bib34","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.3390\/diagnostics11112155","article-title":"Controlling droplet marangoni flows to improve microscopy-based TB diagnosis","volume":"11","author":"Pearlman","year":"2021","journal-title":"Diagnostics"},{"key":"10.1016\/j.ijtb.2025.06.014_bib35","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1007\/s42770-021-00520-4","article-title":"Highly specific and sensitive detection of the Mycobacterium tuberculosis complex using multiplex loop-mediated isothermal amplification combined with a nanoparticle-based lateral flow biosensor","volume":"52","author":"Chen","year":"2021","journal-title":"Braz J Microbiol"},{"key":"10.1016\/j.ijtb.2025.06.014_bib36","doi-asserted-by":"crossref","DOI":"10.1186\/1477-3155-11-38","article-title":"Isothermal DNA amplification coupled to Au-nanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis","volume":"11","author":"Veigas","year":"2013","journal-title":"J Nanobiotechnol"},{"key":"10.1016\/j.ijtb.2025.06.014_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2019.02135","article-title":"Development and clinical validation of multiple cross displacement amplification combined with nanoparticles-based biosensor for detection of Mycobacterium tuberculosis: preliminary results","volume":"10","author":"Jiao","year":"2019","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ijtb.2025.06.014_bib38","doi-asserted-by":"crossref","DOI":"10.1186\/s12866-021-02328-6","article-title":"Two target genes based multiple cross displacement amplification combined with a lateral flow biosensor for the detection of Mycobacterium tuberculosis complex","volume":"21","author":"Huang","year":"2021","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.ijtb.2025.06.014_bib39","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3349\/ymj.2016.57.1.88","article-title":"Comparative evaluation of several gene targets for designing a Multiplex-PCR for an early diagnosis of extrapulmonary tuberculosis","volume":"57","author":"Raj","year":"2015","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.ijtb.2025.06.014_bib40","article-title":"Automated diagnosis and phenotyping of tuberculosis using serum metabolic fingerprints","author":"Liu","year":"2024","journal-title":"Adv Sci"},{"key":"10.1016\/j.ijtb.2025.06.014_bib41","doi-asserted-by":"crossref","first-page":"342","DOI":"10.3390\/bios13030342","article-title":"Reduced graphene oxide-polydopamine-gold nanoparticles: a ternary nanocomposite-based electrochemical genosensor for rapid and early Mycobacterium tuberculosis detection","volume":"13","author":"Chaturvedi","year":"2023","journal-title":"Biosensors"},{"key":"10.1016\/j.ijtb.2025.06.014_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2023.1131840","article-title":"Portable paper-based electrochemiluminescence test incorporating lateral-flow immunosensors for detection of interferon-\u03b3 levels","volume":"11","author":"Yuan","year":"2023","journal-title":"Front Bioeng Biotechnol"},{"key":"10.1016\/j.ijtb.2025.06.014_bib43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0238298","article-title":"Direct-from-sputum rapid phenotypic drug susceptibility test for mycobacteria","volume":"15","author":"Butler","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.ijtb.2025.06.014_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.653853","article-title":"Development of ESAT-6 based immunosensor for the detection of Mycobacterium tuberculosis","volume":"12","author":"Omar","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.ijtb.2025.06.014_bib45","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.msec.2016.12.051","article-title":"Detection of ESAT-6 by a label free miniature immuno-electrochemical biosensor as a diagnostic tool for tuberculosis","volume":"74","author":"Diouani","year":"2016","journal-title":"Mater Sci Eng C"},{"key":"10.1016\/j.ijtb.2025.06.014_bib46","doi-asserted-by":"crossref","first-page":"8523","DOI":"10.2147\/IJN.S181052","article-title":"Detection of Mycobacterium tuberculosis purified ESAT-6 (Rv3875) by magnetic bead-coupled gold nanoparticle-based immuno-PCR assay","volume":"13","author":"Singh","year":"2018","journal-title":"Int J Nanomed"},{"key":"10.1016\/j.ijtb.2025.06.014_bib47","doi-asserted-by":"crossref","first-page":"6029","DOI":"10.2147\/IJN.S171400","article-title":"Identification of mycolic acid forms using surface-enhanced Raman scattering as a fast detection method for tuberculosis","volume":"13","author":"Perumal","year":"2018","journal-title":"Int J Nanomed"},{"key":"10.1016\/j.ijtb.2025.06.014_bib48","first-page":"3969","volume":"vol 114","author":"Liu","year":"2017"},{"key":"10.1016\/j.ijtb.2025.06.014_bib49","doi-asserted-by":"crossref","first-page":"7998","DOI":"10.1021\/acs.analchem.6b01152","article-title":"LOC-SERS: a promising closed system for the identification of mycobacteria","volume":"88","author":"M\u00fchlig","year":"2016","journal-title":"Anal Chem"},{"key":"10.1016\/j.ijtb.2025.06.014_bib50","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-019-4259-x","article-title":"Use of nanotechnology for infectious disease diagnostics: application in drug resistant tuberculosis","volume":"19","author":"Karunaratne","year":"2019","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.ijtb.2025.06.014_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.tube.2023.102340","article-title":"Evolution of tuberculosis diagnostics: from molecular strategies to nanodiagnostics","volume":"140","author":"Mukherjee","year":"2023","journal-title":"Tuberculosis"}],"container-title":["Indian Journal of Tuberculosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019570725001404?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0019570725001404?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T19:13:53Z","timestamp":1765134833000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0019570725001404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":51,"alternative-id":["S0019570725001404"],"URL":"https:\/\/doi.org\/10.1016\/j.ijtb.2025.06.014","relation":{},"ISSN":["0019-5707"],"issn-type":[{"value":"0019-5707","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nanoparticle-based biosensor- from existing to advanced tools in diagnosis of tuberculosis","name":"articletitle","label":"Article Title"},{"value":"Indian Journal of Tuberculosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijtb.2025.06.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Tuberculosis Association of India. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}