{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T21:44:07Z","timestamp":1789767847780,"version":"4.0.1"},"reference-count":77,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunobiology"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.imbio.2005.10.007","type":"journal-article","created":{"date-parts":[[2005,10,21]],"date-time":"2005-10-21T07:13:38Z","timestamp":1129878818000},"page":"761-768","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Annexin A5 in cardiovascular disease and systemic lupus erythematosus"],"prefix":"10.1016","volume":"210","author":[{"given":"Anna","family":"Cederholm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Frosteg\u00e5rd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.imbio.2005.10.007_bib1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S1054-8807(04)00004-3","article-title":"The vulnerable atherosclerotic plaque: pathogenesis and therapeutic approach","volume":"13","author":"Aikawa","year":"2004","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.imbio.2005.10.007_bib2","doi-asserted-by":"crossref","first-page":"17907","DOI":"10.1016\/S0021-9258(19)37128-5","article-title":"Clustering of lipid-bound annexin V may explain its anticoagulant effect","volume":"267","author":"Andree","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2005.10.007_bib3","doi-asserted-by":"crossref","first-page":"4634","DOI":"10.1021\/bi00068a022","article-title":"Aggregation of phospholipid vesicles by a chimeric protein with the N-terminus of annexin I and the core of annexin V","volume":"32","author":"Andree","year":"1993","journal-title":"Biochemistry"},{"key":"10.1016\/j.imbio.2005.10.007_bib4","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1021\/pr049968a","article-title":"Nuclear medicine in the era of genomics and proteomics: lessons from annexin V","volume":"3","author":"Belhocine","year":"2004","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.imbio.2005.10.007_bib5","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1038\/nm1102-1218","article-title":"Innate and acquired immunity in atherogenesis","volume":"8","author":"Binder","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.imbio.2005.10.007_bib6","first-page":"713","article-title":"Cardiovascular disease a hazard despite improved prognosis in patients with systemic lupus erythematosus: results from a Swedish population based study 1964\u201395","volume":"31","author":"Bjornadal","year":"2004","journal-title":"J. Rheumatol"},{"key":"10.1016\/j.imbio.2005.10.007_bib7","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1378\/chest.117.3.834","article-title":"Radionuclide imaging of acute lung transplant rejection with annexin V","volume":"117","author":"Blankenberg","year":"2000","journal-title":"Chest"},{"key":"10.1016\/j.imbio.2005.10.007_bib8","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1128\/MCB.23.8.2907-2913.2003","article-title":"Annexin A5 is not essential for skeletal development","volume":"23","author":"Brachvogel","year":"2003","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.imbio.2005.10.007_bib9","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1073\/pnas.93.4.1624","article-title":"Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus","volume":"93","author":"Casciola-Rosen","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.imbio.2005.10.007_bib10","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1161\/01.ATV.0000150415.18759.36","article-title":"Decreased binding of annexin v to endothelial cells: a potential mechanism in atherothrombosis of patients with systemic lupus erythematosus","volume":"25","author":"Cederholm","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.imbio.2005.10.007_bib11","doi-asserted-by":"crossref","unstructured":"Cervera, R., Asherson, R.A., 2005. Antiphospholipid syndrome associated with infections: clinical and microbiological characteristics. Immunobiology, this issue.","DOI":"10.1016\/j.imbio.2005.10.003"},{"key":"10.1016\/j.imbio.2005.10.007_bib12","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1006\/geno.1994.1201","article-title":"Organization of the human annexin V (ANX5) gene","volume":"20","author":"Cookson","year":"1994","journal-title":"Genomics"},{"key":"10.1016\/j.imbio.2005.10.007_bib13","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1016\/S0021-9258(17)40901-X","article-title":"Identification and purification of an adrenal medullary protein (synexin) that causes calcium-dependent aggregation of isolated chromaffin granules","volume":"253","author":"Creutz","year":"1978","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2005.10.007_bib14","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1182\/blood-2004-03-1095","article-title":"Tissue factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation","volume":"106","author":"Del Conde","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.imbio.2005.10.007_bib15","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1042\/BST0330418","article-title":"The role of blood cells and their microparticles in blood coagulation","volume":"33","author":"Eilertsen","year":"2005","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.imbio.2005.10.007_bib16","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1002\/1529-0131(200110)44:10<2331::AID-ART395>3.0.CO;2-I","article-title":"Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosus","volume":"44","author":"Esdaile","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.imbio.2005.10.007_bib17","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0167-4838(99)00266-6","article-title":"Regulation of blood coagulation","volume":"1477","author":"Esmon","year":"2000","journal-title":"Biochim. Biophys. Acta,"},{"key":"10.1016\/j.imbio.2005.10.007_bib18","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S1568-9972(02)00144-1","article-title":"Antiphospholipid syndrome: pathogenic mechanisms","volume":"2","author":"Espinosa","year":"2003","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.imbio.2005.10.007_bib19","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0021-9150(99)00011-8","article-title":"Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines","volume":"145","author":"Frostegard","year":"1999","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.imbio.2005.10.007_bib20","doi-asserted-by":"crossref","first-page":"5572","DOI":"10.1021\/bi00391a053","article-title":"Human placental anticoagulant protein: isolation and characterization","volume":"26","author":"Funakoshi","year":"1987","journal-title":"Biochemistry"},{"key":"10.1016\/j.imbio.2005.10.007_bib21","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1152\/physrev.00030.2001","article-title":"Annexins: from structure to function","volume":"82","author":"Gerke","year":"2002","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.imbio.2005.10.007_bib22","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nrm1661","article-title":"Annexins: linking Ca (2+) signalling to membrane dynamics","volume":"6","author":"Gerke","year":"2005","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.imbio.2005.10.007_bib23","first-page":"45","article-title":"Immunocytochemical analyses of annexin V (CaBP33) in a human-derived glioma cell line","volume":"323","author":"Giambanco","year":"1993","journal-title":"Expression of annexin V depends on cellular growth state. FEBS Lett."},{"key":"10.1016\/j.imbio.2005.10.007_bib24","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1182\/blood.V100.6.2081","article-title":"A common polymorphism in the annexin V Kozak sequence (-1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients","volume":"100","author":"Gonzalez-Conejero","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.imbio.2005.10.007_bib25","first-page":"169","article-title":"Detection of activated T lymphocytes in the human atherosclerotic plaque","volume":"135","author":"Hansson","year":"1989","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.imbio.2005.10.007_bib26","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1161\/01.RES.0000029784.15893.10","article-title":"Innate and adaptive immunity in the pathogenesis of atherosclerosis","volume":"91","author":"Hansson","year":"2002","journal-title":"Circ. Res."},{"key":"10.1016\/j.imbio.2005.10.007_bib27","doi-asserted-by":"crossref","unstructured":"Harel, M., Aron-Maor, A., Sherer, Y., Blank, M., Shoenfeld, Y., 2005. The infectious etiology of the antiphospholipid syndrome: links betweeen infection and autoimmunity. Immunobiology, this issue.","DOI":"10.1016\/j.imbio.2005.10.004"},{"key":"10.1016\/j.imbio.2005.10.007_bib28","doi-asserted-by":"crossref","first-page":"3867","DOI":"10.1002\/j.1460-2075.1990.tb07605.x","article-title":"The crystal and molecular structure of human annexin V, an anticoagulant protein that binds to calcium and membranes","volume":"9","author":"Huber","year":"1990","journal-title":"EMBO J"},{"key":"10.1016\/j.imbio.2005.10.007_bib29","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/jb\/mvh071","article-title":"Human annexin V binds to sulfatide: contribution to regulation of blood coagulation","volume":"135","author":"Ida","year":"2004","journal-title":"J. Biochem. (Tokyo),"},{"key":"10.1016\/j.imbio.2005.10.007_bib30","first-page":"540","article-title":"A study of human annexin V derivative: its effects of anticoagulation and antithrombosis","volume":"25","author":"Ju","year":"2004","journal-title":"Zhonghua Xue Ye Xue Za Zhi"},{"key":"10.1016\/j.imbio.2005.10.007_bib31","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1007\/BF01745240","article-title":"Purification of cardiac annexin V from the beagle dog heart and changes in its localization in the ischemic rat heart","volume":"9","author":"Kaneko","year":"1994","journal-title":"Heart Vessels"},{"key":"10.1016\/j.imbio.2005.10.007_bib32","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0009-8981(96)06294-8","article-title":"Measurement of plasma annexin V by ELISA in the early detection of acute myocardial infarction","volume":"251","author":"Kaneko","year":"1996","journal-title":"Clin. Chim. Acta,"},{"key":"10.1016\/j.imbio.2005.10.007_bib33","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1111\/j.1538-7836.2003.0543g.x","article-title":"The C-1T mutation in the annexin A5 Kozak sequence slightly increases the risk of myocardial infarction in men","volume":"1","author":"Kenis","year":"2003","journal-title":"J. Thromb. Haemostasis,"},{"key":"10.1016\/j.imbio.2005.10.007_bib34","doi-asserted-by":"crossref","first-page":"52623","DOI":"10.1074\/jbc.M409009200","article-title":"Cell surface-expressed phosphatidylserine and annexin A5 open a novel portal of cell entry","volume":"279","author":"Kenis","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2005.10.007_bib35","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0014-5793(00)02326-7","article-title":"Differential effects of annexins I, II, III, and V on cytosolic phospholipase A2 activity: specific interaction model","volume":"489","author":"Kim","year":"2001","journal-title":"FEBS Lett."},{"key":"10.1016\/j.imbio.2005.10.007_bib36","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1053\/joca.1999.0304","article-title":"Activation of annexin II and V expression, terminal differentiation, mineralization and apoptosis in human osteoarthritic cartilage","volume":"8","author":"Kirsch","year":"2000","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.imbio.2005.10.007_bib37","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0955-3886(97)00013-1","article-title":"Annexin V, a new marker of platelet storage lesion: correlation with dMPV","volume":"18","author":"Krailadsiri","year":"1997","journal-title":"Transfusion Sci."},{"key":"10.1016\/j.imbio.2005.10.007_bib38","first-page":"309","article-title":"Feasibility of 99mTc-annexin V for repetitive detection of apoptotic tumor response to chemotherapy: an experimental study using a rat tumor model","volume":"45","author":"Kuge","year":"2004","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.imbio.2005.10.007_bib39","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1038\/nm1102-1257","article-title":"Stabilization of atherosclerotic plaques: new mechanisms and clinical targets","volume":"8","author":"Libby","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.imbio.2005.10.007_bib40","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1097\/00001721-199310000-00011","article-title":"Intrinsic procoagulant surface induced by hypercholesterolaemia on rabbit aortic endothelium","volume":"4","author":"Lupu","year":"1993","journal-title":"Blood Coagul. Fibrin."},{"key":"10.1016\/j.imbio.2005.10.007_bib41","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/28204","article-title":"Reduction of atherosclerosis in mice by inhibition of CD40 signalling","volume":"394","author":"Mach","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.imbio.2005.10.007_bib42","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1161\/01.CIR.101.8.841","article-title":"Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes","volume":"101","author":"Mallat","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.imbio.2005.10.007_bib43","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1136\/ard.59.5.321","article-title":"Inflammation-mediated rheumatic diseases and atherosclerosis","volume":"59","author":"Manzi","year":"2000","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imbio.2005.10.007_bib44","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1093\/oxfordjournals.aje.a009122","article-title":"Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study","volume":"145","author":"Manzi","year":"1997","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.imbio.2005.10.007_bib45","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0009-8981(00)00218-7","article-title":"Measurement of urinary annexin V by ELISA and its significance as a new urinary-marker of kidney disease","volume":"298","author":"Matsuda","year":"2000","journal-title":"Clin. Chim. Acta,"},{"key":"10.1016\/j.imbio.2005.10.007_bib46","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1016\/S0140-6736(97)11084-4","article-title":"Acute respiratory-tract infections and risk of first-time acute myocardial infarction","volume":"351","author":"Meier","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.imbio.2005.10.007_bib47","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1056\/NEJM199904013401303","article-title":"Annexin II and bleeding in acute promyelocytic leukemia","volume":"340","author":"Menell","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imbio.2005.10.007_bib48","doi-asserted-by":"crossref","first-page":"10474","DOI":"10.1074\/jbc.272.16.10474","article-title":"Inhibition of cytosolic phospholipase A2 by annexin V in differentiated permeabilized HL-60 cells. Evidence of crucial importance of domain I type II Ca2+-binding site in the mechanism of inhibition","volume":"272","author":"Mira","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2005.10.007_bib49","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/gb-2004-5-4-219","article-title":"The annexins","volume":"5","author":"Moss","year":"2004","journal-title":"Genome Biol."},{"key":"10.1016\/j.imbio.2005.10.007_bib50","first-page":"517","article-title":"Annexin V does not represent a diagnostic alternative to myoglobin for early detection of myocardial infarction","volume":"48","author":"Peetz","year":"2002","journal-title":"Clin. Lab."},{"key":"10.1016\/j.imbio.2005.10.007_bib51","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/0002-9343(92)90578-Y","article-title":"Risk factors for coronary artery disease in patients with systemic lupus erythematosus","volume":"93","author":"Petri","year":"1992","journal-title":"Am. J. Med."},{"key":"10.1016\/j.imbio.2005.10.007_bib52","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1146\/annurev.biochem.69.1.419","article-title":"Platelet-activating factor and related lipid mediators","volume":"69","author":"Prescott","year":"2000","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.imbio.2005.10.007_bib53","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1042\/bj3170343","article-title":"Phosphatidylserine-mediated adhesion of T-cells to endothelial cells","volume":"317","author":"Qu","year":"1996","journal-title":"Biochem. J."},{"key":"10.1016\/j.imbio.2005.10.007_bib54","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1056\/NEJM199904013401310","article-title":"\u201cAnnexinopathies\u201d\u2014a new class of diseases","volume":"340","author":"Rand","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imbio.2005.10.007_bib55","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1161\/hh0102.102795","article-title":"Molecular pathogenesis of the antiphospholipid syndrome","volume":"90","author":"Rand","year":"2002","journal-title":"Circ. Res."},{"key":"10.1016\/j.imbio.2005.10.007_bib56","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/S0002-9440(10)63479-7","article-title":"Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: evidence from atomic force microscopy and functional assay","volume":"163","author":"Rand","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.imbio.2005.10.007_bib57","doi-asserted-by":"crossref","first-page":"6028","DOI":"10.1074\/jbc.M411710200","article-title":"Annexin A5 down-regulates surface expression of tissue factor: a novel mechanism of regulating the membrane receptor repertoir","volume":"280","author":"Ravassa","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2005.10.007_bib58","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0304-4157(94)90019-1","article-title":"Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins","volume":"1197","author":"Raynal","year":"1994","journal-title":"Biochim. Biophys. Acta,"},{"key":"10.1016\/j.imbio.2005.10.007_bib59","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/j.1432-1033.1985.tb09150.x","article-title":"Isolation and partial purification of a novel anticoagulant from arteries of human umbilical cord","volume":"151","author":"Reutelingsperger","year":"1985","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.imbio.2005.10.007_bib60","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1078\/0171-2985-00211","article-title":"Endothelium as a target for antiphospholipid antibodies","volume":"207","author":"Riboldi","year":"2003","journal-title":"Immunobiology"},{"key":"10.1016\/j.imbio.2005.10.007_bib61","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis\u2014an inflammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imbio.2005.10.007_bib62","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/S0140-6736(00)04239-2","article-title":"Systemic lupus erythematosus","volume":"357","author":"Ruiz-Irastorza","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.imbio.2005.10.007_bib63","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.thromres.2004.04.012","article-title":"Annexin V inhibits lipopolysaccharide-induced procoagulant activity on human monocytes","volume":"114","author":"Sato","year":"2004","journal-title":"Thromb. Res."},{"key":"10.1016\/j.imbio.2005.10.007_bib64","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1006\/jmbi.1993.1627","article-title":"The crystal structure of a new high-calcium form of annexin V","volume":"234","author":"Sopkova","year":"1993","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.imbio.2005.10.007_bib65","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/00005792-199207000-00004","article-title":"Cardiovascular disease in systemic lupus erythematosus. A study of 75 patients form a defined population","volume":"71","author":"Sturfelt","year":"1992","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.imbio.2005.10.007_bib66","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1161\/hc4101.097518","article-title":"Risk factors for cardiovascular disease in systemic lupus erythematosus","volume":"104","author":"Svenungsson","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.imbio.2005.10.007_bib67","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1191\/0961203303lu412oa","article-title":"TNF-alpha: a link between hypertriglyceridaemia and inflammation in SLE patients with cardiovascular disease","volume":"12","author":"Svenungsson","year":"2003","journal-title":"Lupus"},{"key":"10.1016\/j.imbio.2005.10.007_bib68","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1002\/art.11264","article-title":"Elevated triglycerides and low levels of high-density lipoprotein as markers of disease activity in association with up-regulation of the tumor necrosis factor alpha\/tumor necrosis factor receptor system in systemic lupus erythematosus","volume":"48","author":"Svenungsson","year":"2003","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.imbio.2005.10.007_bib69","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1161\/01.CIR.96.7.2339","article-title":"Inhibition of arterial thrombosis by recombinant annexin V in a rabbit carotid artery injury model","volume":"96","author":"Thiagarajan","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.imbio.2005.10.007_bib70","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0002-9343(76)90431-9","article-title":"The bimodal mortality pattern of systemic lupus erythematosus","volume":"60","author":"Urowitz","year":"1976","journal-title":"Am. J. Med."},{"key":"10.1016\/j.imbio.2005.10.007_bib71","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1161\/01.CIR.91.1.23","article-title":"Anti-cardiolipin antibodies and risk of myocardial infarction in a prospective cohort of middle-aged men","volume":"91","author":"Vaarala","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.imbio.2005.10.007_bib72","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1007\/BF01322533","article-title":"Membrane related effects in endothelial cells induced by human cytomegalovirus","volume":"140","author":"van Geelen","year":"1995","journal-title":"Arch. Virol."},{"key":"10.1016\/j.imbio.2005.10.007_bib73","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1182\/blood-2003-01-0187","article-title":"The -1C>T mutation in the annexin A5 gene does not affect plasma levels of annexin A5","volume":"101","author":"van Heerde","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.imbio.2005.10.007_bib74","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1161\/01.ATV.0000157979.51673.2c","article-title":"C-reactive protein and annexin A5 bind to distinct sites of negatively charged phospholipids present in oxidized low-density lipoprotein","volume":"25","author":"van Tits","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.imbio.2005.10.007_bib75","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0022-1759(95)00072-I","article-title":"A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V","volume":"184","author":"Vermes","year":"1995","journal-title":"J. Immunol. Methods,"},{"key":"10.1016\/j.imbio.2005.10.007_bib76","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1002\/1531-8257(199911)14:6<1008::AID-MDS1015>3.0.CO;2-E","article-title":"Decreased concentration of annexin V in parkinsonian cerebrospinal fluid: speculation on the underlying cause","volume":"14","author":"Vermes","year":"1999","journal-title":"Movement Disord."},{"key":"10.1016\/j.imbio.2005.10.007_bib77","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S1471-4906(01)02089-0","article-title":"Atherosclerosis as an autoimmune disease: an update","volume":"22","author":"Wick","year":"2001","journal-title":"Trends Immunol."}],"container-title":["Immunobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298505001452?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298505001452?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T16:20:57Z","timestamp":1759249257000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171298505001452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":77,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0171298505001452"],"URL":"https:\/\/doi.org\/10.1016\/j.imbio.2005.10.007","relation":{},"ISSN":["0171-2985"],"issn-type":[{"value":"0171-2985","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Annexin A5 in cardiovascular disease and systemic lupus erythematosus","name":"articletitle","label":"Article Title"},{"value":"Immunobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imbio.2005.10.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}