{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:10:06Z","timestamp":1761743406903,"version":"build-2065373602"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunobiology"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1016\/j.imbio.2010.08.004","type":"journal-article","created":{"date-parts":[[2010,8,20]],"date-time":"2010-08-20T06:39:37Z","timestamp":1282286377000},"page":"528-534","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Complement mediated hepatocytes injury in a model of autoantibody induced hepatitis"],"prefix":"10.1016","volume":"216","author":[{"given":"Zhidan","family":"Tu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Shiue","family":"Chou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Chuang","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Meyerson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion G.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Bu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John J.","family":"Fung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiguang","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.imbio.2010.08.004_bib0005","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.humpath.2007.12.014","article-title":"An immunohistochemical evaluation of C4d deposition in pediatric inflammatory liver diseases","volume":"39","author":"Bouron-Dal Soglio","year":"2008","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0010","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jaut.2008.04.015","article-title":"Hepatitis resulting from liver-specific expression and recognition of self-antigen","volume":"31","author":"Buxbaum","year":"2008","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.imbio.2010.08.004_bib0015","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/MOG.0b013e3282f57268","article-title":"Autoimmune liver disease","volume":"24","author":"Czaja","year":"2008","journal-title":"Curr. Opin. Gastroenterol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0020","first-page":"549","article-title":"Progress in the diagnosis and treatment of autoimmune hepatitis","volume":"99","author":"Czaja","year":"2008","journal-title":"Minerva Med."},{"key":"10.1016\/j.imbio.2010.08.004_bib0025","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/MOG.0b013e328324ed06","article-title":"Autoimmune liver disease","volume":"25","author":"Czaja","year":"2009","journal-title":"Curr. Opin. Gastroenterol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0030","doi-asserted-by":"crossref","first-page":"3665","DOI":"10.1073\/pnas.70.12.3665","article-title":"Activation of human complement by human lymphoid cells sensitized with histocompatibility alloantisera","volume":"70","author":"Ferrone","year":"1973","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.imbio.2010.08.004_bib0035","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1002\/eji.1830230630","article-title":"Mouse Crry\/p65 is a regulator of the alternative pathway of complement activation","volume":"23","author":"Foley","year":"1993","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0040","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1016\/j.molimm.2009.04.005","article-title":"Primary human hepatocytes are protected against complement by multiple regulators","volume":"46","author":"Halme","year":"2009","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0045","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0022-1759(88)90427-9","article-title":"Measurement of cytotoxicity by target cell release and retention of the fluorescent dye bis-carboxyethyl-carboxyfluorescein (BCECF)","volume":"108","author":"Kolber","year":"1988","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.imbio.2010.08.004_bib0050","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1056\/NEJMra050408","article-title":"Autoimmune hepatitis","volume":"354","author":"Krawitt","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imbio.2010.08.004_bib0055","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.expneurol.2006.06.003","article-title":"Deficiency of decay accelerating factor and CD59 leads to crisis in experimental myasthenia","volume":"202","author":"Kaminski","year":"2006","journal-title":"Minerva Exp. Neurol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0060","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.bbrc.2009.03.025","article-title":"Mouse CD4+ CD25+ T regulatory cells are protected from autologous complement mediated injury by Crry and CD59","volume":"382","author":"Li","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.imbio.2010.08.004_bib0065","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1046\/j.1365-2567.2001.01287.x","article-title":"Tissue distribution of products of the mouse decay-accelerating factor (DAF) genes. Exploitation of a Daf1 knock-out mouse and site-specific monoclonal antibodies","volume":"104","author":"Lin","year":"2001","journal-title":"Immunology"},{"key":"10.1016\/j.imbio.2010.08.004_bib0070","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/abbi.2001.2488","article-title":"Bulk production and functional analyses of mouse CD55's native and deglycosylated active domains","volume":"393","author":"Lin","year":"2001","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.imbio.2010.08.004_bib0075","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1365-2249.1992.tb03037.x","article-title":"Liver-infiltrating T helper cells in autoimmune chronic active hepatitis stimulate the production of autoantibodies against the human asialoglycoprotein receptor in vitro","volume":"88","author":"Lohr","year":"1992","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0080","doi-asserted-by":"crossref","first-page":"4295","DOI":"10.4049\/jimmunol.151.8.4295","article-title":"Mouse Crry\/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF","volume":"151","author":"Li","year":"1993","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0085","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1172\/JCI0216086","article-title":"Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay-accelerating factor protection","volume":"110","author":"Lin","year":"2002","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.imbio.2010.08.004_bib0090","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1084\/jem.160.5.1558","article-title":"Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes","volume":"160","author":"Medof","year":"1984","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2010.08.004_bib0095","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s002510050447","article-title":"Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1","volume":"48","author":"Miwa","year":"1998","journal-title":"Immunogenetics"},{"key":"10.1016\/j.imbio.2010.08.004_bib0100","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1155\/2008\/642432","article-title":"Autoimmune hepatitis in a North American Aboriginal\/First Nations population","volume":"22","author":"Minuk","year":"2008","journal-title":"Can. J. Gastroenterol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0105","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.4049\/jimmunol.137.4.1275","article-title":"Natural killer cells are deficient in the surface expression of the complement regulatory protein, decay accelerating factor (DAF)","volume":"137","author":"Nicholson-Weller","year":"1986","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0110","first-page":"333","article-title":"The complement system in liver diseases","volume":"3","author":"Qin","year":"2006","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0115","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1002\/eji.1830180821","article-title":"Distribution of membrane cofactor protein of complement on human peripheral blood cells. An altered form is found on granulocytes","volume":"18","author":"Seya","year":"1988","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0120","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0016-5085(94)90178-3","article-title":"Expression of complement-regulatory proteins in normal and UW-preserved human liver","volume":"107","author":"Scoazec","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1016\/j.imbio.2010.08.004_bib0125","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1046\/j.1365-2249.2000.01305.x","article-title":"Cytokine-mediated up-regulation of CD55 and CD59 protects human hepatoma cells from complement attack","volume":"121","author":"Spiller","year":"2000","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.imbio.2010.08.004_bib0130","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1084\/jem.163.4.837","article-title":"Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b","volume":"163","author":"Seya","year":"1986","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2010.08.004_bib0135","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0162-3109(00)80299-4","article-title":"Complement inhibitors: a resurgent concept in anti-inflammatory therapeutics","volume":"49","author":"Sahu","year":"2000","journal-title":"Immunopharmacology"},{"key":"10.1016\/j.imbio.2010.08.004_bib0140","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0022-1759(99)00008-3","article-title":"Efficient generation of monoclonal antibodies against surface-expressed proteins by hyperexpression in rodent cells","volume":"224","author":"Spiller","year":"1999","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.imbio.2010.08.004_bib0145","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/0016-5085(94)90129-5","article-title":"Demographics of anti-asialoglycoprotein receptor autoantibodies in autoimmune hepatitis","volume":"107","author":"Treichel","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1016\/j.imbio.2010.08.004_bib0150","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/hep.20377","article-title":"A novel IgM class autoantibody to a hepatocyte-related 190kDa molecule in patients with type 1 autoimmune hepatitis","volume":"40","author":"Yamauchi","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.imbio.2010.08.004_bib0155","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/S0016-5085(03)01066-7","article-title":"Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement","volume":"125","author":"Zhao","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.imbio.2010.08.004_bib0160","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/hep.20726","article-title":"A murine model of acute liver injury induced by human monoclonal autoantibody","volume":"42","author":"Yamauchi","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.imbio.2010.08.004_bib0165","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1084\/jem.166.4.947","article-title":"Inhibition of antibody-dependent lymphocyte cytotoxicity by homologous restriction factor incorporated into target cell membranes","volume":"166","author":"Zalman","year":"1987","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2010.08.004_bib0170","doi-asserted-by":"crossref","first-page":"8562","DOI":"10.4049\/jimmunol.179.12.8562","article-title":"Anti-C5 antibody treatment ameliorates weakness in experimentally acquired myasthenia gravis","volume":"179","author":"Zhou","year":"2007","journal-title":"J. Immunol."}],"container-title":["Immunobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298510001403?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298510001403?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T16:26:35Z","timestamp":1759249595000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171298510001403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["S0171298510001403"],"URL":"https:\/\/doi.org\/10.1016\/j.imbio.2010.08.004","relation":{},"ISSN":["0171-2985"],"issn-type":[{"type":"print","value":"0171-2985"}],"subject":[],"published":{"date-parts":[[2011,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Complement mediated hepatocytes injury in a model of autoantibody induced hepatitis","name":"articletitle","label":"Article Title"},{"value":"Immunobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imbio.2010.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}