{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:07:50Z","timestamp":1791259670789,"version":"4.1.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunobiology"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.imbio.2013.06.008","type":"journal-article","created":{"date-parts":[[2013,6,25]],"date-time":"2013-06-25T16:16:07Z","timestamp":1372176967000},"page":"17-24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["IDO expressing fibroblasts promote the expansion of antigen specific regulatory T cells"],"prefix":"10.1016","volume":"219","author":[{"given":"Terry-Ann","family":"Curran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza Baradar","family":"Jalili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Farrokhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aziz","family":"Ghahary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.imbio.2013.06.008_bib0015","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1182\/blood-2008-11-191197","article-title":"Indoleamine 2,3-dioxygenase\u2013expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells","volume":"114","author":"Chung","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.imbio.2013.06.008_bib0020","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1182\/blood-2006-07-036863","article-title":"Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25\u2212 into CD25+ T regulatory cells","volume":"109","author":"Curti","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.imbio.2013.06.008_bib0025","doi-asserted-by":"crossref","first-page":"19871","DOI":"10.1016\/S0021-9258(17)45453-6","article-title":"Regulation of indoleamine 2,3-dioxygenase gene expression in human fibroblasts by interferon-gamma. Upstream control region discriminates between interferon-gamma and interferon-alpha","volume":"265","author":"Dai","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2013.06.008_bib0030","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1160\/TH09-04-0250","article-title":"Antimicrobial and immunoregulatory effector mechanisms in human endothelial cells","volume":"102","author":"Daubener","year":"2009","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.imbio.2013.06.008_bib0035","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.humimm.2008.05.006","article-title":"Regulatory T cells after organ transplantation: where does their action take place?","volume":"3","author":"Dijke","year":"2008","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.imbio.2013.06.008_bib0040","doi-asserted-by":"crossref","first-page":"6499","DOI":"10.4049\/jimmunol.1101398","article-title":"Inducible CD4+LAP+Foxp3\u2212 regulatory T cells suppress allergic inflammation","volume":"187","author":"Duan","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2013.06.008_bib0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11010-007-9635-y","article-title":"Differential immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO) on primary human CD4+ and CD8+ T cells","volume":"309","author":"Forouzandeh","year":"2008","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.imbio.2013.06.008_bib0050","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1524-475X.2008.00377.x","article-title":"Skin cells, but not T cells, are resistant to indoleamine 2,3-dioxygenase (IDO) expressed by allogeneic fibroblasts","volume":"16","author":"Forouzandeh","year":"2008","journal-title":"Wound Repair Regen."},{"key":"10.1016\/j.imbio.2013.06.008_bib0055","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1111\/j.1524-475X.2010.00635.x","article-title":"Local expression of indoleamine 2,3-dioxygenase suppresses T-cell-mediated rejection of an engineered bilayer skin substitute","volume":"18","author":"Forouzandeh","year":"2010","journal-title":"Wound Repair Regen."},{"key":"10.1016\/j.imbio.2013.06.008_bib0070","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.2337\/db09-1560","article-title":"Local expression of indoleamine 2,3 dioxygenase in syngeneic fibroblasts significantly prolongs survival of an engineered three-dimensional islet allograft","volume":"59","author":"Jalili","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.imbio.2013.06.008_bib0080","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.1182\/blood-2008-12-195073","article-title":"Interferon-\u03b3-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells","volume":"114","author":"J\u00fcrgens","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.imbio.2013.06.008_bib0085","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.1600-065X.2008.00610.x","article-title":"Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape","volume":"222","author":"Katz","year":"2008","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imbio.2013.06.008_bib0090","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1016\/j.biocel.2007.01.004","article-title":"Molecules in focus: indoleamine 2,3-dioxygenase","volume":"39","author":"King","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.imbio.2013.06.008_bib0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1440-1711.1999.00795.x","article-title":"The role of CTLA-4 in the regulation of T cell immune responses","volume":"77","author":"McCoy","year":"1999","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.imbio.2013.06.008_bib0110","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1038\/nri1485","article-title":"Regulatory T cells: friend or foe in immunity to infection?","volume":"4","author":"Mills","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.imbio.2013.06.008_bib0115","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.immuni.2005.03.013","article-title":"GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase","volume":"22","author":"Munn","year":"2005","journal-title":"Immunity"},{"key":"10.1016\/j.imbio.2013.06.008_bib0120","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1126\/science.281.5380.1191","article-title":"Prevention of allogeneic fetal rejection by tryptophan catabolism","volume":"281","author":"Munn","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.imbio.2013.06.008_bib0130","doi-asserted-by":"crossref","first-page":"5608","DOI":"10.4049\/jimmunol.0804116","article-title":"Constitutive expression of IDO by dendritic cells of mesenteric lymph nodes: functional involvement of the CTLA-4\/B7 and CCL22\/CCR4 interactions","volume":"183","author":"Onodera","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2013.06.008_bib0145","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1089\/jir.1986.6.267","article-title":"Characterisation of an indolamine 2,3-dioxygenase induced by gamma-interferon in cultured human fibroblasts","volume":"6","author":"Pfefferkorn","year":"1986","journal-title":"J. Interferon Res."},{"key":"10.1016\/j.imbio.2013.06.008_bib0150","doi-asserted-by":"crossref","first-page":"5968","DOI":"10.4049\/jimmunol.177.9.5968","article-title":"Subepithelial myofibroblasts are novel nonprofessional APCs in the human colonic mucosa","volume":"177","author":"Saada","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2013.06.008_bib0160","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/S0960-9822(95)00219-3","article-title":"Antigen-presenting cells. Professionals and amateurs","volume":"5","author":"Sprent","year":"1995","journal-title":"Curr. Biol."},{"key":"10.1016\/j.imbio.2013.06.008_bib0165","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1073\/pnas.0508996103","article-title":"Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase","volume":"103","author":"Sugimoto","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.imbio.2013.06.008_bib0170","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1111\/j.1600-6143.2007.01960.x","article-title":"Role of IFN\u03b3 in allograft tolerance mediated by CD4+CD25+ regulatory T cells by induction of IDO in endothelial cells","volume":"7","author":"Thebault","year":"2007","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.imbio.2013.06.008_bib0175","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/1074-7613(94)90071-X","article-title":"CTLA-4 can function as a negative regulator of T cell activation","volume":"1","author":"Walunas","year":"1994","journal-title":"Immunity"}],"container-title":["Immunobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298513001216?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298513001216?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T16:35:57Z","timestamp":1759250157000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171298513001216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S0171298513001216"],"URL":"https:\/\/doi.org\/10.1016\/j.imbio.2013.06.008","relation":{},"ISSN":["0171-2985"],"issn-type":[{"value":"0171-2985","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"IDO expressing fibroblasts promote the expansion of antigen specific regulatory T cells","name":"articletitle","label":"Article Title"},{"value":"Immunobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imbio.2013.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier GmbH. Published by Elsevier GmbH All rights reserved.","name":"copyright","label":"Copyright"}]}}