{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:25:11Z","timestamp":1762521911087,"version":"build-2065373602"},"reference-count":169,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI114710","AI118161","AI119327","AI114790","AI111728"],"award-info":[{"award-number":["AI114710","AI118161","AI119327","AI114790","AI111728"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunobiology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.imbio.2016.05.016","type":"journal-article","created":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T02:30:05Z","timestamp":1464748205000},"page":"1110-1123","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: Lessons from the pathogenic Neisseriae"],"prefix":"10.1016","volume":"221","author":[{"given":"Sanjay","family":"Ram","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jutamas","family":"Shaughnessy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosane B.","family":"DeOliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa A.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunita","family":"Gulati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A.","family":"Rice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.imbio.2016.05.016_bib0005","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.molimm.2010.11.015","article-title":"Interactions between Bordetella pertussis and the complement inhibitor factor H","volume":"48","author":"Amdahl","year":"2011","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0010","doi-asserted-by":"crossref","unstructured":"Anderson, R.M., May, R.M., 1991. Infectious Diseases of Humans: Dynamics and Control Oxford Science Publications, 768.","DOI":"10.1093\/oso\/9780198545996.001.0001"},{"key":"10.1016\/j.imbio.2016.05.016_bib0015","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1021\/bi00167a032","article-title":"Lipopolysaccharides of Campylobacter jejuni serotype O:19: structures of core oligosaccharide regions from the serostrain and two bacterial isolates from patients with the Guillain-Barre syndrome","volume":"33","author":"Aspinall","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/j.imbio.2016.05.016_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.coi.2015.04.002","article-title":"Host-pathogen interaction during bacterial vaccination","volume":"36","author":"Barnett","year":"2015","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0025","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1128\/IAI.01037-07","article-title":"The opportunistic human pathogenic fungus Aspergillus fumigatus evades the host complement system","volume":"76","author":"Behnsen","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0030","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1189\/jlb.0807526","article-title":"Subversion of complement activation at the bacterial surface promotes serum resistance and opsonophagocytosis of Francisella tularensis","volume":"84","author":"Ben Nasr","year":"2008","journal-title":"J. Leukoc. Biol."},{"issue":"8","key":"10.1016\/j.imbio.2016.05.016_bib0035","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1093\/infdis\/jiu241","article-title":"Outer membrane protein OlpA contributes to moraxella catarrhalis serum resistance via interaction with factor H and the alternative pathway","volume":"210","author":"Bernhard","year":"2014","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.imbio.2016.05.016_bib0040","doi-asserted-by":"crossref","first-page":"18685","DOI":"10.1074\/jbc.M113.459040","article-title":"Structural basis for complement evasion by Lyme disease pathogen Borrelia burgdorferi","volume":"288","author":"Bhattacharjee","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0045","doi-asserted-by":"crossref","first-page":"4520","DOI":"10.1016\/j.jprot.2012.04.013","article-title":"Variable regions in the sushi domains 6\u20137 and 19\u201320 of factor H in animals and human lead to change in the affinity to factor H binding protein of Borrelia","volume":"75","author":"Bhide","year":"2012","journal-title":"J. Proteom."},{"key":"10.1016\/j.imbio.2016.05.016_bib0050","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.1128\/IAI.00313-08","article-title":"Characterization of complement factor H binding to Yersinia enterocolitica serotype O:3","volume":"76","author":"Biedzka-Sarek","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0055","doi-asserted-by":"crossref","first-page":"3520","DOI":"10.1016\/S0021-9258(19)70850-3","article-title":"Biosynthesis of sialic acids by Neisseria meningitidis","volume":"237","author":"Blacklow","year":"1962","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0060","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nchembio.1696","article-title":"Structural basis for sialic acid-mediated self-recognition by complement factor H","volume":"11","author":"Blaum","year":"2015","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0065","doi-asserted-by":"crossref","first-page":"5093","DOI":"10.1016\/j.vaccine.2006.03.091","article-title":"Neisseria meningitidis group B correlates of protection and assay standardization\u2014international meeting report emory university, Atlanta, Georgia, United States, 16\u201317 march 2005","volume":"24","author":"Borrow","year":"2006","journal-title":"Vaccine"},{"key":"10.1016\/j.imbio.2016.05.016_bib0070","article-title":"Antibiotic resistance threats in the United States, 2013, department of health and human services","author":"CDC","year":"2013","journal-title":"Cent. Dis. Control Prev."},{"key":"10.1016\/j.imbio.2016.05.016_bib0075","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1002\/eji.1830191126","article-title":"Regulation of the human alternative complement pathway: formation of a ternary complex between factor H, surface-bound C3b and chemical groups on nonactivating surfaces","volume":"19","author":"Carreno","year":"1989","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0080","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1093\/infdis\/jir875","article-title":"Leptospiral immunoglobulin-like proteins interact with human complement regulators factor H, FHL-1, FHR-1, and C4BP","volume":"205","author":"Castiblanco-Valencia","year":"2012","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.imbio.2016.05.016_bib0085","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1086\/382752","article-title":"Variable degree of alternative complement pathway-mediated hemolysis in Indian visceral leishmaniasis induced by differential expression of 9-O-acetylated sialoglycans","volume":"189","author":"Chava","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.imbio.2016.05.016_bib0090","doi-asserted-by":"crossref","first-page":"19111","DOI":"10.1073\/pnas.0605668103","article-title":"West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H","volume":"103","author":"Chung","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.imbio.2016.05.016_bib0095","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/1574-6976.12056","article-title":"Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules","volume":"38","author":"Cress","year":"2014","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.imbio.2016.05.016_bib0100","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1099\/13500872-141-4-913","article-title":"Effect of sialylation of lipopolysaccharide of Neisseria gonorrhoeae on recognition and complement-mediated killing by monoclonal antibodies directed against different outer-membrane antigens","volume":"141","author":"de la Paz","year":"1995","journal-title":"Microbiology"},{"key":"10.1016\/j.imbio.2016.05.016_bib0105","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.1128\/IAI.68.7.3894-3899.2000","article-title":"The lipopolysaccharide structures of Salmonella enterica serovar Typhimurium and Neisseria gonorrhoeae determine the attachment of human mannose-binding lectin to intact organisms","volume":"68","author":"Devyatyarova-Johnson","year":"2000","journal-title":"Infect. Immun."},{"issue":"Suppl","key":"10.1016\/j.imbio.2016.05.016_bib0110","first-page":"66","article-title":"Interaction of human factor H with PspC of Streptococcus pneumoniae","volume":"119","author":"Dave","year":"2004","journal-title":"Indian J. Med. Res."},{"key":"10.1016\/j.imbio.2016.05.016_bib0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2249.2007.03552.x","article-title":"Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H","volume":"151","author":"de Cordoba","year":"2008","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0120","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.imbio.2012.07.021","article-title":"Complement dysregulation and disease: from genes and proteins to diagnostics and drugs","volume":"217","author":"de Cordoba","year":"2012","journal-title":"Immunobiology"},{"key":"10.1016\/j.imbio.2016.05.016_bib0125","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/sji.12070","article-title":"Humoral pattern recognition and the complement system","volume":"78","author":"Degn","year":"2013","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0130","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1093\/ndt\/gft470","article-title":"Outbreak of Escherichia coli O104:H4 haemolytic uraemic syndrome in France: outcome with eculizumab","volume":"29","author":"Delmas","year":"2014","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.imbio.2016.05.016_bib0135","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2146\/ajhp140134","article-title":"Safe and effective use of eculizumab in the treatment of severe Shiga toxin Escherichia coli-associated hemolytic uremic syndrome","volume":"72","author":"Dinh","year":"2015","journal-title":"Am. J. Health Syst. Pharm."},{"key":"10.1016\/j.imbio.2016.05.016_bib0140","doi-asserted-by":"crossref","first-page":"5604","DOI":"10.1128\/IAI.70.10.5604-5611.2002","article-title":"The human complement regulator factor H binds pneumococcal surface protein PspC via short consensus repeats 13\u201315","volume":"70","author":"Duthy","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0145","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1126\/science.1110189","article-title":"Complement factor H polymorphism and age-related macular degeneration","volume":"308","author":"Edwards","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.imbio.2016.05.016_bib0150","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1111\/j.1365-2958.1992.tb01439.x","article-title":"Antibodies to N-terminal peptides of gonococcal porin are bactericidal when gonococcal lipopolysaccharide is not sialylated","volume":"6","author":"Elkins","year":"1992","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0155","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/BF00873691","article-title":"Kinetics of conversion of Neisseria gonorrhoeae to resistance to complement by cytidine 5'-monophospho-N-acetyl neuraminic acid","volume":"67","author":"Emond","year":"1995","journal-title":"Antonie Van Leeuwenhoek"},{"key":"10.1016\/j.imbio.2016.05.016_bib0160","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1093\/hmg\/ddi066","article-title":"Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32","volume":"14","author":"Esparza-Gordillo","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.imbio.2016.05.016_bib0165","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1016\/j.molimm.2005.11.008","article-title":"Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree","volume":"43","author":"Esparza-Gordillo","year":"2006","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0170","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1073\/pnas.75.4.1971","article-title":"Regulation by membrane sialic acid of beta1H-dependent decay- dissociation of amplification C3 convertase of the alternative complement pathway","volume":"75","author":"Fearon","year":"1978","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.imbio.2016.05.016_bib0175","doi-asserted-by":"crossref","first-page":"7009","DOI":"10.4049\/jimmunol.0804031","article-title":"The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome","volume":"182","author":"Ferreira","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0180","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1128\/CMR.4.3.359","article-title":"Infectious diseases associated with complement deficiencies","volume":"4","author":"Figueroa","year":"1991","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.imbio.2016.05.016_bib0185","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/BF02918259","article-title":"Complement deficiency states and meningococcal disease","volume":"12","author":"Figueroa","year":"1993","journal-title":"Immunol. Res."},{"key":"10.1016\/j.imbio.2016.05.016_bib0190","doi-asserted-by":"crossref","first-page":"5913","DOI":"10.4049\/jimmunol.1303449","article-title":"Identification of a Haemophilus influenzae factor H-binding lipoprotein involved in serum resistance","volume":"192","author":"Fleury","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0195","doi-asserted-by":"crossref","first-page":"4948","DOI":"10.1182\/blood-2008-01-133702","article-title":"Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome","volume":"112","author":"Fremeaux-Bacchi","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.imbio.2016.05.016_bib0200","doi-asserted-by":"crossref","first-page":"8624","DOI":"10.4049\/jimmunol.181.12.8624","article-title":"Factor H binding as a complement evasion mechanism for an anaerobic pathogen, Fusobacterium necrophorum","volume":"181","author":"Friberg","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0205","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1084\/jem.160.6.1640","article-title":"C3b covalently bound to IgG demonstrates a reduced rate of inactivation by factors H and I","volume":"160","author":"Fries","year":"1984","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0210","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1073\/pnas.86.5.1669","article-title":"Molecular characterization and expression in Escherichia coli of the gene complex encoding the polysaccharide capsule of Neisseria meningitidis group B","volume":"86","author":"Frosch","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"Suppl. 2","key":"10.1016\/j.imbio.2016.05.016_bib0215","doi-asserted-by":"crossref","first-page":"S150","DOI":"10.1093\/infdis\/174.Supplement_2.S150","article-title":"Sexually transmitted diseases and sexual behavior: insights from mathematical models","volume":"174","author":"Garnett","year":"1996","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.imbio.2016.05.016_bib0220","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1128\/IAI.02984-14","article-title":"Binding of complement factor H to PorB3 and NspA enhances resistance of Neisseria meningitidis to anti-factor H binding protein bactericidal activity","volume":"83","author":"Giuntini","year":"2015","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0225","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1093\/infdis\/174.6.1223","article-title":"Immunogenicity of Neisseria gonorrhoeae lipooligosaccharide epitope 2C7, widely expressed in vivo with no immunochemical similarity to human glycosphingolipids","volume":"174","author":"Gulati","year":"1996","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.imbio.2016.05.016_bib0230","doi-asserted-by":"crossref","first-page":"4078","DOI":"10.4049\/jimmunol.168.8.4078","article-title":"Regulation of the Mannan-binding lectin pathway of complement on Neisseria gonorrhoeae by C1-inhibitor and alpha(2)-macroglobulin","volume":"168","author":"Gulati","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0235","doi-asserted-by":"crossref","first-page":"7390","DOI":"10.1128\/IAI.73.11.7390-7397.2005","article-title":"Enhanced factor H binding to sialylated Gonococci is restricted to the sialylated lacto-N-neotetraose lipooligosaccharide species: implications for serum resistance and evidence for a bifunctional lipooligosaccharide sialyltransferase in Gonococci","volume":"73","author":"Gulati","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0240","doi-asserted-by":"crossref","first-page":"3416","DOI":"10.4049\/jimmunol.1102746","article-title":"Properdin is critical for antibody-dependent bactericidal activity against Neisseria gonorrhoeae that recruit C4b-binding protein","volume":"188","author":"Gulati","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0245","doi-asserted-by":"crossref","first-page":"e1003559","DOI":"10.1371\/journal.ppat.1003559","article-title":"Immunization against a saccharide epitope accelerates clearance of experimental Gonococcal infection","volume":"9","author":"Gulati","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.imbio.2016.05.016_bib0250","doi-asserted-by":"crossref","first-page":"e1005290","DOI":"10.1371\/journal.ppat.1005290","article-title":"Utilizing CMP-sialic acid analogs to unravel Neisseria gonorrhoeae lipooligosaccharide-mediated complement resistance and design novel therapeutics","volume":"11","author":"Gulati","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.imbio.2016.05.016_bib0255","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1126\/science.1110359","article-title":"Complement factor H variant increases the risk of age-related macular degeneration","volume":"308","author":"Haines","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.imbio.2016.05.016_bib0260","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/978-3-319-18603-0_4","article-title":"Complement involvement in periodontitis: molecular mechanisms and rational therapeutic approaches","volume":"865","author":"Hajishengallis","year":"2015","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0265","doi-asserted-by":"crossref","first-page":"537","DOI":"10.4049\/jimmunol.181.1.537","article-title":"Haemophilus influenzae interacts with the human complement inhibitor factor H","volume":"181","author":"Hallstrom","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0270","doi-asserted-by":"crossref","first-page":"4939","DOI":"10.4049\/jimmunol.1200386","article-title":"Dihydrolipoamide dehydrogenase of Pseudomonas aeruginosa is a surface-exposed immune evasion protein that binds three members of the factor H family and plasminogen","volume":"189","author":"Hallstrom","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0275","doi-asserted-by":"crossref","first-page":"5848","DOI":"10.4049\/jimmunol.178.9.5848","article-title":"The host immune regulator factor H interacts via two contact sites with the PspC protein of Streptococcus pneumoniae and mediates adhesion to host epithelial cells","volume":"178","author":"Hammerschmidt","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0280","doi-asserted-by":"crossref","first-page":"8427","DOI":"10.1074\/jbc.M007994200","article-title":"The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi","volume":"276","author":"Hellwage","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0285","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1042\/CS20090513","article-title":"Cellular and molecular biology of Neisseria meningitidis colonization and invasive disease","volume":"118","author":"Hill","year":"2010","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.imbio.2016.05.016_bib0290","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.4049\/jimmunol.1001244","article-title":"Human complement factor H binds to outer membrane protein Rck of Salmonella","volume":"185","author":"Ho","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0295","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.4049\/jimmunol.1201145","article-title":"The Yersinia pseudotuberculosis outer membrane protein Ail recruits the human complement regulatory protein factor H","volume":"189","author":"Ho","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0300","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1055\/s-0034-1375297","article-title":"Complement factor H-antibody-associated hemolytic uremic syndrome: pathogenesis, clinical presentation, and treatment","volume":"40","author":"Hofer","year":"2014","journal-title":"Semin. Thromb. Hemost."},{"issue":"6286","key":"10.1016\/j.imbio.2016.05.016_bib0305","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1126\/science.aad8373","article-title":"Complement and microglia mediate early synapse loss in Alzheimer mouse models","volume":"352","author":"Hong","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.imbio.2016.05.016_bib0310","doi-asserted-by":"crossref","first-page":"12361","DOI":"10.1074\/jbc.M110.181750","article-title":"Lipooligosaccharide of Campylobacter jejuni: similarity with multiple types of mammalian glycans beyond gangliosides","volume":"286","author":"Houliston","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0315","first-page":"211","article-title":"Serum bactericidal action and activation of the classic and alternate complement pathways by Neisseria gonorrhoeae","volume":"92","author":"Ingwer","year":"1978","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0320","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.vetmic.2012.07.008","article-title":"Decoration of Histophilus somni lipooligosaccharide with N-acetyl-5-neuraminic acid enhances bacterial binding of complement factor H and resistance to killing by serum and polymorphonuclear leukocytes","volume":"161","author":"Inzana","year":"2012","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0325","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.4049\/jimmunol.168.4.1886","article-title":"Streptococcus pneumoniae evades complement attack and opsonophagocytosis by expressing the pspC locus-encoded Hic protein that binds to short consensus repeats 8\u201311 of factor H","volume":"168","author":"Jarva","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0330","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0161-5890(99)00104-2","article-title":"Assembly and regulation of the complement amplification loop in blood: the role of C3b-C3b-IgG complexes","volume":"36","author":"Jelezarova","year":"1999","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0335","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1042\/bj3490217","article-title":"Interaction of C3b(2)\u2014IgG complexes with complement proteins properdin, factor B and factor H: implications for amplification","volume":"349","author":"Jelezarova","year":"2000","journal-title":"Biochem. J."},{"key":"10.1016\/j.imbio.2016.05.016_bib0340","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3389\/fmicb.2011.00107","article-title":"Estradiol-treated female mice as surrogate hosts for Neisseria gonorrhoeae genital tract infections","volume":"2","author":"Jerse","year":"2011","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0345","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1073\/pnas.1017087108","article-title":"Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement","volume":"108","author":"Kajander","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"year":"2000","series-title":"Pneumococcal Polysaccharides: A Chemical View","author":"Kamerling","key":"10.1016\/j.imbio.2016.05.016_bib0350"},{"key":"10.1016\/j.imbio.2016.05.016_bib0355","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1007\/s00467-010-1555-5","article-title":"Genetics and complement in atypical HUS","volume":"25","author":"Kavanagh","year":"2010","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0360","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1084\/jem.150.5.1202","article-title":"Surface-associated heparin inhibits zymosan-induced activation of the human alternative complement pathway by augmenting the regulatory action of the control proteins on particle-bound C3b","volume":"150","author":"Kazatchkine","year":"1979","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0365","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1111\/j.1574-6968.2009.01820.x","article-title":"Serum resistance of Acinetobacter baumannii through the binding of factor H to outer membrane proteins","volume":"301","author":"Kim","year":"2009","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.imbio.2016.05.016_bib0370","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1126\/science.1109557","article-title":"Complement factor H polymorphism in age-related macular degeneration","volume":"308","author":"Klein","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.imbio.2016.05.016_bib0375","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1002\/1521-4141(200106)31:6<1674::AID-IMMU1674>3.0.CO;2-2","article-title":"Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1\/reconectin and Factor H","volume":"31","author":"Kraiczy","year":"2001","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0380","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.4049\/jimmunol.179.5.2979","article-title":"Immune evasion of the human pathogen Pseudomonas aeruginosa: elongation factor Tuf is a factor H and plasminogen binding protein","volume":"179","author":"Kunert","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0385","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1056\/NEJMc1100859","article-title":"Eculizumab in severe shiga-toxin-associated HUS","volume":"364","author":"Lapeyraque","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0390","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1128\/IAI.00613-07","article-title":"Defining targets for complement components C4b and C3b on the pathogenic neisseriae","volume":"76","author":"Lewis","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0395","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1128\/IAI.01280-08","article-title":"Phosphoethanolamine substitution of lipid A and resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides and complement-mediated killing by normal human serum","volume":"77","author":"Lewis","year":"2009","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0400","doi-asserted-by":"crossref","first-page":"e1001027","DOI":"10.1371\/journal.ppat.1001027","article-title":"The meningococcal vaccine candidate neisserial surface protein a (NspA) binds to factor H and enhances meningococcal resistance to complement","volume":"6","author":"Lewis","year":"2010","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.imbio.2016.05.016_bib0405","doi-asserted-by":"crossref","first-page":"5063","DOI":"10.4049\/jimmunol.1103748","article-title":"The relative roles of factor H binding protein, neisserial surface protein A, and lipooligosaccharide sialylation in regulation of the alternative pathway of complement on meningococci","volume":"188","author":"Lewis","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0410","unstructured":"Lewis, L.A., Carter, M., Burbage, J., Chaves, B., Beluchukwu, A., Gulati, S., Rice, P.A., Ram, S., 2012. The role of gonococcal Neisserial surface protein A in serum resistance and comparison of its factor H binding properties with that of its meningococcal counterpart, Wuerzburg, Germany, 389 pp."},{"key":"10.1016\/j.imbio.2016.05.016_bib0415","doi-asserted-by":"crossref","first-page":"e00339","DOI":"10.1128\/mBio.00339-13","article-title":"Factor H-dependent alternative pathway inhibition mediated by porin B contributes to virulence of Neisseria meningitidis","volume":"4","author":"Lewis","year":"2013","journal-title":"MBio"},{"key":"10.1016\/j.imbio.2016.05.016_bib0420","doi-asserted-by":"crossref","first-page":"e02465","DOI":"10.1128\/mBio.02465-14","article-title":"Alpha-2,3-sialyltransferase expression level impacts the kinetics of lipooligosaccharide sialylation, complement resistance, and the ability of Neisseria gonorrhoeae to colonize the murine genital tract","volume":"6","author":"Lewis","year":"2015","journal-title":"MBio"},{"key":"10.1016\/j.imbio.2016.05.016_bib0425","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1098\/rsif.2007.0229","article-title":"Patterns of antigenic diversity and the mechanisms that maintain them","volume":"4","author":"Lipsitch","year":"2007","journal-title":"J. R. Soc. Interface"},{"key":"10.1016\/j.imbio.2016.05.016_bib0430","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s40246-015-0029-z","article-title":"Complement regulator CD46: genetic variants and disease associations","volume":"9","author":"Liszewski","year":"2015","journal-title":"Hum. Genom."},{"key":"10.1016\/j.imbio.2016.05.016_bib0435","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1750-1172-6-60","article-title":"Atypical hemolytic uremic syndrome","volume":"6","author":"Loirat","year":"2011","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.imbio.2016.05.016_bib0440","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1128\/CVI.00055-11","article-title":"Characterization of Neisseria meningitidis isolates that do not express the virulence factor and vaccine antigen factor H binding protein","volume":"18","author":"Lucidarme","year":"2011","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0445","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1086\/340649","article-title":"Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H","volume":"185","author":"Meri","year":"2002","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.imbio.2016.05.016_bib0450","doi-asserted-by":"crossref","first-page":"501","DOI":"10.4049\/jimmunol.177.1.501","article-title":"The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance","volume":"177","author":"Madico","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0455","doi-asserted-by":"crossref","first-page":"4489","DOI":"10.4049\/jimmunol.178.7.4489","article-title":"Factor H binding and function in sialylated pathogenic neisseriae is influenced by gonococcal, but not meningococcal, porin","volume":"178","author":"Madico","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0460","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/S0171-2985(11)80352-9","article-title":"Lipo-oligosaccharides (LOS) of mucosal pathogens: molecular mimicry and host-modification of LOS","volume":"187","author":"Mandrell","year":"1993","journal-title":"Immunobiology"},{"key":"10.1016\/j.imbio.2016.05.016_bib0465","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1084\/jem.168.1.107","volume":"168","author":"Mandrell","year":"1988","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0470","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1084\/jem.171.5.1649","article-title":"In vitro and in vivo modification of Neisseria gonorrhoeae lipooligosaccharide epitope structure by sialylation","volume":"171","author":"Mandrell","year":"1990","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0475","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.1128\/jb.173.9.2823-2832.1991","article-title":"Endogenous sialylation of the lipooligosaccharides of Neisseria meningitidis","volume":"173","author":"Mandrell","year":"1991","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0480","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1128\/iai.60.7.3017-3020.1992","article-title":"Further antigenic similarities of Neisseria gonorrhoeae lipooligosaccharides and human glycosphingolipids","volume":"60","author":"Mandrell","year":"1992","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0485","doi-asserted-by":"crossref","first-page":"3967","DOI":"10.1096\/fj.09-138149","article-title":"Acquisition of factor H by a novel surface protein on group B Streptococcus promotes complement degradation","volume":"23","author":"Maruvada","year":"2009","journal-title":"FASEB J."},{"key":"10.1016\/j.imbio.2016.05.016_bib0490","doi-asserted-by":"crossref","first-page":"7126","DOI":"10.1128\/IAI.73.11.7126-7132.2005","article-title":"Demonstration of factor H-like protein 1 binding to Treponema denticola, a pathogen associated with periodontal disease in humans","volume":"73","author":"McDowell","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0495","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.molimm.2015.02.032","article-title":"Age-related macular degeneration and the role of the complement system","volume":"67","author":"McHarg","year":"2015","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0500","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1086\/314545","article-title":"Complement processing and immunoglobulin binding to Neisseria gonorrhoeae determined in vitro simulates in vivo effects","volume":"179","author":"McQuillen","year":"1999","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.imbio.2016.05.016_bib0505","doi-asserted-by":"crossref","first-page":"3982","DOI":"10.1073\/pnas.87.10.3982","article-title":"Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid\/polyanion binding site on factor H","volume":"87","author":"Meri","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.imbio.2016.05.016_bib0510","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1006\/bbrc.1994.1008","article-title":"Regulation of alternative pathway complement activation by glycosaminoglycans: specificity of the polyanion binding site on factor H","volume":"198","author":"Meri","year":"1994","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0515","doi-asserted-by":"crossref","first-page":"4157","DOI":"10.1128\/IAI.00007-06","article-title":"Relapsing fever spirochetes Borrelia recurrentis and B. duttonii acquire complement regulators C4b-binding protein and factor H","volume":"74","author":"Meri","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0520","doi-asserted-by":"crossref","first-page":"e1003308","DOI":"10.1371\/journal.ppat.1003308","article-title":"Microbes bind complement inhibitor factor H via a common site","volume":"9","author":"Meri","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.imbio.2016.05.016_bib0525","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.4049\/jimmunol.140.5.1588","article-title":"Inhibition of the alternative pathway of human complement by structural analogues of sialic acid","volume":"140","author":"Michalek","year":"1988","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0530","first-page":"3295","article-title":"Cytidine 5\u2032-monophospho-N-acetylneuraminic acid or a related compound is the low Mr factor from human red blood cells which induces gonococcal resistance to killing by human serum","volume":"134","author":"Nairn","year":"1988","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0535","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.molimm.2015.03.246","article-title":"Atypical aHUS: State of the art","volume":"67","author":"Nester","year":"2015","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0540","doi-asserted-by":"crossref","first-page":"3426","DOI":"10.4049\/jimmunol.180.5.3426","article-title":"Human factor H interacts selectively with Neisseria gonorrhoeae and results in species-specific complement evasion","volume":"180","author":"Ngampasutadol","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0545","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1056\/NEJM198504253121704","article-title":"Deficiency of the complement regulatory protein, decay-accelerating factor, on membranes of granulocytes, monocytes, and platelets in paroxysmal nocturnal hemoglobinuria","volume":"312","author":"Nicholson-Weller","year":"1985","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0550","doi-asserted-by":"crossref","first-page":"7119","DOI":"10.1128\/IAI.71.12.7119-7128.2003","article-title":"Recruitment of complement factor H-like protein 1 promotes intracellular invasion by group A streptococci","volume":"71","author":"Pandiripally","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0555","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1073\/pnas.75.5.2416","article-title":"Complement C3 convertase: cell surface restriction of beta1 H control and generation of restriction on neuraminidase-treated cells","volume":"75","author":"Pangburn","year":"1978","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.imbio.2016.05.016_bib0560","doi-asserted-by":"crossref","first-page":"5430","DOI":"10.1073\/pnas.80.17.5430","article-title":"Deficiency of an erythrocyte membrane protein with complement regulatory activity in paroxysmal nocturnal hemoglobinuria","volume":"80","author":"Pangburn","year":"1983","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.imbio.2016.05.016_bib0565","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0882-4010(88)90103-9","article-title":"Cytidine 5\u2032-monophospho-N-acetyl neuraminic acid and a low molecular weight factor from human red blood cells induce lipopolysaccharide alteration in gonococci when conferring resistance to killing by human serum","volume":"5","author":"Parsons","year":"1988","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.imbio.2016.05.016_bib0570","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0882-4010(89)90112-5","article-title":"Sialylation of lipopolysaccharide and loss of absorption of bactericidal antibody during conversion of gonococci to serum resistance by cytidine 5\u2032-monophospho-N-acetyl neuraminic acid","volume":"7","author":"Parsons","year":"1989","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.imbio.2016.05.016_bib0575","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1006\/mpat.1993.1032","article-title":"Identification by mass spectrometry of CMP-NANA in diffusible material released from high M(r) blood cell fractions that confers serum resistance on gonococci","volume":"14","author":"Parsons","year":"1993","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.imbio.2016.05.016_bib0580","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1006\/mpat.1994.1041","article-title":"Sialylation of lipopolysaccharide by CMP-NANA in viable gonococci is enhanced by low Mr material released from blood cell extracts but not by some UDP sugars","volume":"16","author":"Parsons","year":"1994","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.imbio.2016.05.016_bib0585","doi-asserted-by":"crossref","first-page":"14146","DOI":"10.1016\/S0021-9258(19)85220-1","article-title":"Structure of the sialylated L3 lipopolysaccharide of Neisseria meningitidis","volume":"268","author":"Pavliak","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0590","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1128\/IAI.06294-11","article-title":"Fhb, a novel factor H-binding surface protein, contributes to the antiphagocytic ability and virulence of Streptococcus suis","volume":"80","author":"Pian","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0595","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/j.1365-2249.2007.03574.x","article-title":"Translational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals","volume":"151","author":"Pickering","year":"2008","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0600","doi-asserted-by":"crossref","first-page":"37537","DOI":"10.1074\/jbc.M707280200","article-title":"Gpm1p is a factor H-, FHL-1-, and plasminogen-binding surface protein of Candida albicans","volume":"282","author":"Poltermann","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0605","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1084\/jem.187.5.743","article-title":"A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae","volume":"187","author":"Ram","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0610","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1128\/CMR.00048-09","article-title":"Infections of people with complement deficiencies and patients who have undergone splenectomy","volume":"23","author":"Ram","year":"2010","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.imbio.2016.05.016_bib0615","doi-asserted-by":"crossref","first-page":"8297","DOI":"10.1074\/jbc.M110.184838","article-title":"Meningococcal group W-135 and Y capsular polysaccharides paradoxically enhance activation of the alternative pathway of complement","volume":"286","author":"Ram","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0620","doi-asserted-by":"crossref","first-page":"4881","DOI":"10.4049\/jimmunol.1003623","article-title":"Novel blocking human IgG directed against the pentapeptide repeat motifs of Neisseria meningitidis Lip\/H.8 and Laz lipoproteins","volume":"186","author":"Ray","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0625","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.clim.2015.08.009","article-title":"Applying complement therapeutics to rare diseases","volume":"161","author":"Reis","year":"2015","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0630","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1084\/jem.164.5.1735","article-title":"Immunoglobulin G antibodies directed against protein III block killing of serum-resistant Neisseria gonorrhoeae by immune serum","volume":"164","author":"Rice","year":"1986","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0635","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1055\/s-0034-1375296","article-title":"Genetics of atypical hemolytic uremic syndrome (aHUS)","volume":"40","author":"Rodriguez de Cordoba","year":"2014","journal-title":"Semin. Thromb. Hemost."},{"key":"10.1016\/j.imbio.2016.05.016_bib0640","first-page":"p34","article-title":"New functional and structural insights from updated mutational databases for complement factor H factor I, membrane cofactor protein and C3","author":"Rodriguez","year":"2014","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.imbio.2016.05.016_bib0645","article-title":"The Plasmodium falciparum blood stages acquire factor h family proteins to evade destruction by human complement","author":"Rosa","year":"2015","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0650","doi-asserted-by":"crossref","first-page":"7292","DOI":"10.4049\/jimmunol.178.11.7292","article-title":"Dual binding specificity of a Borrelia hermsii-associated complement regulator-acquiring surface protein for factor H and plasminogen discloses a putative virulence factor of relapsing fever spirochetes","volume":"178","author":"Rossmann","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0655","doi-asserted-by":"crossref","first-page":"e111194","DOI":"10.1371\/journal.pone.0111194","article-title":"Pasteurella pneumotropica evades the human complement system by acquisition of the complement regulators factor H and C4BP","volume":"9","author":"Sahagun-Ruiz","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.imbio.2016.05.016_bib0660","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1084\/jem.174.6.1601","article-title":"Expression of paragloboside-like lipooligosaccharides may be a necessary component of gonococcal pathogenesis in men","volume":"174","author":"Schneider","year":"1991","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0665","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1038\/nature07769","article-title":"Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates","volume":"458","author":"Schneider","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.imbio.2016.05.016_bib0670","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1128\/IAI.00089-10","article-title":"Molecular characterization of the interaction of Borrelia parkeri and Borrelia turicatae with human complement regulators","volume":"78","author":"Schott","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0675","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.molimm.2014.06.032","article-title":"Genetic variants in the complement system predisposing to age-related macular degeneration: a review","volume":"61","author":"Schramm","year":"2014","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0680","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1172\/JCI113897","article-title":"Interaction of Neisseria gonorrhoeae with classical complement components, C1-inhibitor, and a monoclonal antibody directed against the Neisserial H.8 antigen","volume":"83","author":"Schweinle","year":"1989","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.imbio.2016.05.016_bib0685","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/nature16549","article-title":"Schizophrenia risk from complex variation of complement component 4","volume":"530","author":"Sekar","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.imbio.2016.05.016_bib0690","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1128\/IAI.00691-09","article-title":"Functional characterization of Borrelia spielmanii outer surface proteins that interact with distinct members of the human factor H protein family and with plasminogen","volume":"78","author":"Seling","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0695","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1128\/iai.65.2.484-487.1997","article-title":"Localization by site-directed mutagenesis of the site in human complement factor H that binds to Streptococcus pyogenes M protein","volume":"65","author":"Sharma","year":"1997","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0700","doi-asserted-by":"crossref","first-page":"e38407","DOI":"10.1371\/journal.pone.0038407","article-title":"Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tactic","volume":"7","author":"Sharp","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.imbio.2016.05.016_bib0705","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1128\/IAI.01561-08","article-title":"Functional comparison of the binding of factor H short consensus repeat 6 (SCR 6) to factor H binding protein from Neisseria meningitidis and the binding of factor H SCR 18\u201320 to Neisseria gonorrhoeae porin","volume":"77","author":"Shaughnessy","year":"2009","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0710","doi-asserted-by":"crossref","first-page":"22235","DOI":"10.1074\/jbc.M111.225516","article-title":"Molecular characterization of the interaction between sialylated Neisseria gonorrhoeae and factor H","volume":"286","author":"Shaughnessy","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0715","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1128\/CVI.00444-14","article-title":"Fusion protein comprising factor H domains 6 and 7 and human IgG1 Fc as an antibacterial immunotherapeutic","volume":"21","author":"Shaughnessy","year":"2014","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0720","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.4049\/jimmunol.1500292","article-title":"A novel factor H-Fc chimeric immunotherapeutic molecule against Neisseria gonorrhoeae","volume":"196","author":"Shaughnessy","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0725","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.chom.2012.11.013","article-title":"Malaria parasites co-opt human factor H to prevent complement-mediated lysis in the mosquito midgut","volume":"13","author":"Simon","year":"2013","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.imbio.2016.05.016_bib0730","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1574-6968.1992.tb05717.x","article-title":"The sialylation of gonococcal lipopolysaccharide by host factors: a major impact on pathogenicity","volume":"79","author":"Smith","year":"1992","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.imbio.2016.05.016_bib0735","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1128\/iai.44.2.452-458.1984","article-title":"Antibody-dependent alternative pathway killing of Haemophilus influenzae type b","volume":"44","author":"Steele","year":"1984","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0740","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00002030-199501000-00003","article-title":"Interaction of several complement proteins with gp120 and gp41, the two envelope glycoproteins of HIV-1","volume":"9","author":"Stoiber","year":"1995","journal-title":"AIDS"},{"key":"10.1016\/j.imbio.2016.05.016_bib0745","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1073\/pnas.94.1.271","article-title":"Capsule switching of Neisseria meningitidis","volume":"94","author":"Swartley","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.imbio.2016.05.016_bib0750","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.4049\/jimmunol.128.4.1772","article-title":"The requirement of specific anticapsular IgG for killing of Haemophilus influenzae by the alternative pathway of complement activation","volume":"128","author":"Tarr","year":"1982","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0755","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.chom.2008.05.004","article-title":"Bacterial genome variability and its impact on vaccine design","volume":"3","author":"Telford","year":"2008","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.imbio.2016.05.016_bib0760","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/978-1-4419-0901-5_5","article-title":"Humoral pattern recognition molecules: Mannan-binding lectin and ficolins","volume":"653","author":"Thiel","year":"2009","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0765","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.4049\/jimmunol.176.3.1305","article-title":"The central role of the alternative complement pathway in human disease","volume":"176","author":"Thurman","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0770","doi-asserted-by":"crossref","first-page":"3604","DOI":"10.1128\/iai.59.10.3604-3609.1991","article-title":"Eight lipooligosaccharides of Neisseria meningitidis react with a monoclonal antibody which binds lacto-N-neotetraose (Gal beta 1\u20134GlcNAc beta 1\u20133Gal beta 1\u20134Glc)","volume":"59","author":"Tsai","year":"1991","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0775","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1128\/CMR.00010-14","article-title":"Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future","volume":"27","author":"Unemo","year":"2014","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.imbio.2016.05.016_bib0780","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1084\/jem.152.3.532","article-title":"An autosomal dominant gene regulates the extent of 9-O-acetylation of murine erythrocyte sialic acids. A probable explanation for the variation in capacity to activate the human alternate complement pathway","volume":"152","author":"Varki","year":"1980","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0785","doi-asserted-by":"crossref","first-page":"158","DOI":"10.4161\/hv.4.2.4871","article-title":"Meningococcal B vaccine development and evaluation of efficacy","volume":"4","author":"van Alphen","year":"2008","journal-title":"Hum. Vaccin"},{"key":"10.1016\/j.imbio.2016.05.016_bib0790","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1046\/j.1432-1327.1998.2540626.x","article-title":"Structure of an alpha-2,6-sialylated lipooligosaccharide from Neisseria meningitidis immunotype L1","volume":"254","author":"Wakarchuk","year":"1998","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0795","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1128\/IAI.73.4.2351-2359.2005","article-title":"Identification and functional characterization of complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes Borrelia afzelii and Borrelia garinii","volume":"73","author":"Wallich","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0800","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/227382a0","article-title":"Gonococci in urethral exudates possess a virulence factor lost on subculture","volume":"227","author":"Ward","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.imbio.2016.05.016_bib0805","doi-asserted-by":"crossref","first-page":"3527","DOI":"10.1016\/S0021-9258(19)70851-5","article-title":"The biosynthesis of cytidine 5\u2032-monophospho-n-acetylneuraminic acid by an enzyme from Neisseria meningitidis","volume":"237","author":"Warren","year":"1962","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imbio.2016.05.016_bib0810","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s10719-015-9624-4","article-title":"Preparation of legionaminic acid analogs of sialo-glycoconjugates by means of mammalian sialyltransferases","volume":"32","author":"Watson","year":"2015","journal-title":"Glycoconj. J."},{"key":"10.1016\/j.imbio.2016.05.016_bib0815","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/nature10449","article-title":"Complement factor H binds malondialdehyde epitopes and protects from oxidative stress","volume":"478","author":"Weismann","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.imbio.2016.05.016_bib0820","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1128\/iai.60.1.39-43.1992","article-title":"Gonococcal lipooligosaccharide sialylation prevents complement- dependent killing by immune sera","volume":"60","author":"Wetzler","year":"1992","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0825","article-title":"Defining the binding region in factor H to develop a therapeutic factor H-Fc fusion protein against nontypeable Haemophilus influenzae","author":"Wong","year":"2016","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.imbio.2016.05.016_bib0830","doi-asserted-by":"crossref","first-page":"4094","DOI":"10.1128\/IAI.00433-06","article-title":"Alpha-2,3-sialyltransferase enhances Neisseria gonorrhoeae survival during experimental murine genital tract infection","volume":"74","author":"Wu","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2016.05.016_bib0835","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1084\/jem.178.5.1771","article-title":"A bacterium lipopolysaccharide that elicits Guillain-Barre syndrome has a GM1 ganglioside-like structure","volume":"178","author":"Yuki","year":"1993","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imbio.2016.05.016_bib0840","doi-asserted-by":"crossref","first-page":"11404","DOI":"10.1073\/pnas.0402391101","article-title":"Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome","volume":"101","author":"Yuki","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"year":"1996","series-title":"Sialylation of LOS Inhibits Gonococcal Killing Primarily Through an Effect on Classical Pathway Activation.","author":"Zaleski","key":"10.1016\/j.imbio.2016.05.016_bib0845"}],"container-title":["Immunobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298516300870?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298516300870?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T16:42:32Z","timestamp":1759250552000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171298516300870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":169,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S0171298516300870"],"URL":"https:\/\/doi.org\/10.1016\/j.imbio.2016.05.016","relation":{},"ISSN":["0171-2985"],"issn-type":[{"type":"print","value":"0171-2985"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: Lessons from the pathogenic Neisseriae","name":"articletitle","label":"Article Title"},{"value":"Immunobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imbio.2016.05.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}