{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T20:48:36Z","timestamp":1773953316637,"version":"3.50.1"},"reference-count":61,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunobiology"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.imbio.2022.152194","type":"journal-article","created":{"date-parts":[[2022,3,6]],"date-time":"2022-03-06T23:02:45Z","timestamp":1646607765000},"page":"152194","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Opportunistic pneumonia caused by E. cuniculi in mice immunosuppressed with cyclophosphamide"],"prefix":"10.1016","volume":"227","author":[{"given":"Iramirton","family":"Figuer\u00eado Moreira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuska","family":"Marcelino Alvares-Saraiva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Cristina P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Guilherme Xavier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diva","family":"Denelle Spadacci-Morena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronalda","family":"Silva de Ara\u00fajo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Ricardo Dell'Armelina Rocha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Anete Lallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.imbio.2022.152194_b0005","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1046\/j.1439-0450.2002.00588.x","article-title":"Fox encephalitozoonosis: isolation of the agent from an outbreak in farmed blue foxes (Alopex lagopus) in Finland and some hitherto unreported pathologic lesions","volume":"49","author":"Akerstedt","year":"2002","journal-title":"J. Vet. Med."},{"issue":"1","key":"10.1016\/j.imbio.2022.152194_b0010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1093\/cid\/ciz156","article-title":"Invasive fungal infection after lung transplantation: epidemiology in the setting of antifungal prophylaxis","volume":"70","author":"Baker","year":"2020","journal-title":"Clin. Infect. Dis."},{"issue":"7","key":"10.1016\/j.imbio.2022.152194_b0015","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1093\/cid\/cir531","article-title":"The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America","volume":"53","author":"Bradley","year":"2011","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.imbio.2022.152194_b0020","first-page":"91","article-title":"Cytokine response to infection with the microsporidian, Encephalitozoon cuniculi","volume":"46","author":"Braunfuchsov\u00e1","year":"1999","journal-title":"Folia Parasitol."},{"key":"10.1016\/j.imbio.2022.152194_b0025","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s12026-009-8149-y","article-title":"High-dose cyclophosphamide for autoimmunity and alloimmunity","volume":"47","author":"Brodsky","year":"2010","journal-title":"Immunol. Res."},{"issue":"1","key":"10.1016\/j.imbio.2022.152194_b0030","first-page":"1","article-title":"Alveolar macrophages prevent lethal influenza pneumonia by inhibiting infection of type-1 alveolar epithelial cells","volume":"13","author":"Cardani","year":"2017","journal-title":"PlosPathog."},{"key":"10.1016\/j.imbio.2022.152194_b0035","doi-asserted-by":"crossref","first-page":"555","DOI":"10.2174\/1381612805666230110214512","article-title":"An overview of cyclophosphamide development and clinical applications","volume":"5","author":"Colvin","year":"1999","journal-title":"Curr. Pharm. Des."},{"issue":"2","key":"10.1016\/j.imbio.2022.152194_b0040","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.imbio.2016.09.018","article-title":"B-1 cell decreases susceptibility to encephalitozoonosis in mice","volume":"222","author":"da Costa","year":"2017","journal-title":"Immunobiol."},{"key":"10.1016\/j.imbio.2022.152194_b0045","unstructured":"Dezern, A.E., Styler, M.J., Drachman, D.B., Hummers, L.K., Jones, R.J., Brodsky, R.A., 2013. Repeated treatment with high dose cyclophosphamide for severe autoimmune diseases. Am J Blood Res. 3, 84\u201390. PMID: 23358715; PMCID: PMC3555191."},{"issue":"9","key":"10.1016\/j.imbio.2022.152194_b0050","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1093\/cid\/ciy723","article-title":"Prevalence and etiology of community-acquired pneumonia in immunocompromised patients","volume":"68","author":"Di Pasquale","year":"2019","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.imbio.2022.152194_b0055","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1128\/EC.00302-08","article-title":"Overview of the presentations on microsporidia and free-living amebae at the 10th International Workshops on Opportunistic Protists","volume":"6","author":"Didier","year":"2009","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.imbio.2022.152194_b0060","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/nrclinonc.2009.146","article-title":"Cyclophosphamide and cancer: golden anniversary","volume":"6","author":"Emadi","year":"2009","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.imbio.2022.152194_b0065","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/j.1574-6976.2011.00318.x","article-title":"T cell response and persistence of the microsporidia","volume":"36","author":"Ghosh","year":"2012","journal-title":"FEMS Microbiol. Rev."},{"issue":"4","key":"10.1016\/j.imbio.2022.152194_b0070","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.apjtm.2017.03.017","article-title":"Microsporidiosis in Iran: a systematic review and meta-analysis","volume":"10","author":"Ghoyounchi","year":"2017","journal-title":"Asian Pac. J. Trop. Med."},{"key":"10.1016\/j.imbio.2022.152194_b0075","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1517\/14740338.2012.712111","article-title":"Safety and interactions of new antifungals in stem cell transplant recipients","volume":"11","author":"Girmenia","year":"2012","journal-title":"Expert Opin. Drug Saf."},{"key":"10.1016\/j.imbio.2022.152194_b0080","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/S0092-8674(02)01201-1","article-title":"Pattern recognition receptors: doubling up for the innate immune response","volume":"111","author":"Gordon","year":"2002","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.imbio.2022.152194_b0085","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-018-3565-z","article-title":"Atypical pathogens in hospitalized patients with community-acquired pneumonia: a worldwide perspective","volume":"18","author":"Gramegna","year":"2018","journal-title":"BMC Infect. Dis."},{"issue":"2","key":"10.1016\/j.imbio.2022.152194_b0090","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.FUNK-0018-2016","article-title":"Microsporidia: obligate intracellular pathogens within the fungal kingdom","volume":"5","author":"Han","year":"2017","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.imbio.2022.152194_b0095","doi-asserted-by":"crossref","first-page":"11612","DOI":"10.1073\/pnas.89.23.11612","article-title":"CD8 T cell can protect against an intracellular bacterium in an interferon g-independent fashion","volume":"89","author":"Harty","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.imbio.2022.152194_b0100","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.1128\/IAI.70.6.2959-2964.2002","article-title":"Induction of Interleukin-12 and Gamma Interferon equires Tumor Necrosis Factor Alpha for Protective T1-Cell-Mediated Immunity to Pulmonary Cryptococcus neoformans Infection","volume":"70","author":"Herring","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2022.152194_b0105","doi-asserted-by":"crossref","first-page":"3507","DOI":"10.4049\/jimmunol.155.7.3507","article-title":"Downregulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans","volume":"155","author":"Huffnagle","year":"1985","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2022.152194_b0110","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nri3600","article-title":"Alveolar macrophages: plasticity in a tissue-specific context","volume":"14","author":"Hussell","year":"2014","journal-title":"Nat. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.imbio.2022.152194_b0115","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1056\/NEJMoa1500245","article-title":"Community-acquired pneumonia requiring hospitalization among U.S. adults","volume":"373","author":"Jain","year":"2015","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.imbio.2022.152194_b0120","doi-asserted-by":"crossref","DOI":"10.1186\/s43008-021-00074-y","article-title":"Fungi of entomopathogenic potential in Chytridiomycota and Blastocladiomycota, and in fungal allies of the Oomycota and Microsporidia","volume":"12","author":"Kaczmarek","year":"2021","journal-title":"IMA Fungus"},{"issue":"2","key":"10.1016\/j.imbio.2022.152194_b0125","doi-asserted-by":"crossref","first-page":"941","DOI":"10.4049\/jimmunol.165.2.941","article-title":"IL-18 contributes to host resistance against infection with Cryptococcus neoformans in mice with defective IL-12 synthesis through induction of IFN \u03b3 production by NK cells","volume":"165","author":"Kawakami","year":"2000","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.imbio.2022.152194_b0130","doi-asserted-by":"crossref","first-page":"462.e5","DOI":"10.1016\/j.cmi.2016.01.014","article-title":"Prevalence and molecular characteristics of urinary and intestinal microsporidia infections in renal transplant recipients","volume":"22","author":"Kicia","year":"2016","journal-title":"Clin. Microbiol. Infect."},{"issue":"8","key":"10.1016\/j.imbio.2022.152194_b0135","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1093\/cid\/ciy256","article-title":"Disseminated Infection of Encephalitozoon cuniculi associated with osteolysis of hip periprosthetic tissue","volume":"67","author":"Kicia","year":"2018","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.imbio.2022.152194_b0140","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ijid.2018.10.016","article-title":"Symptomatic respiratory Encephalitozoon cuniculi infection in renal transplant recipients","volume":"79","author":"Kicia","year":"2019","journal-title":"Int. J. Infect. Dis."},{"issue":"4","key":"10.1016\/j.imbio.2022.152194_b0145","doi-asserted-by":"crossref","first-page":"e60941","DOI":"10.1371\/journal.pone.0060941","article-title":"Latent microsporidiosis caused by Encephalitozoon cuniculi in immunocompetent hosts: a murine model demonstrating the ineffectiveness of the immune system and treatment with albendazole","volume":"8","author":"Kotkova","year":"2013","journal-title":"PLoS ONE"},{"issue":"3","key":"10.1016\/j.imbio.2022.152194_b0150","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.exppara.2012.04.019","article-title":"Encephalitozoonosis in pharmacologically immunosuppressed mice","volume":"131","author":"Lallo","year":"2012","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.imbio.2022.152194_b0155","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1128\/AAC.00157-13","article-title":"Effect of three drugs against Encephalitozoon cuniculi infection in immunosuppressed mice","volume":"57","author":"Lallo","year":"2013","journal-title":"Antimicrobial Agents Chemother."},{"issue":"11","key":"10.1016\/j.imbio.2022.152194_b0160","doi-asserted-by":"crossref","first-page":"5457","DOI":"10.1128\/IAI.66.11.5457-5461.1998","article-title":"Gamma Interferon production by cytotoxic T lymphocytes is required for resolution of Chlamydia trachomatis infection","volume":"66","author":"Lampe","year":"1998","journal-title":"Infect. Immun."},{"issue":"3","key":"10.1016\/j.imbio.2022.152194_b0165","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.micinf.2017.11.004","article-title":"B-1 cells upregulate CD8 T lymphocytes and increase proinflammatory cytokines serum levels in oral encephalitozoonosis","volume":"20","author":"Langanke Dos Santos","year":"2018","journal-title":"Microbes Infect."},{"key":"10.1016\/j.imbio.2022.152194_b0170","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1159\/000337434","article-title":"Heterogeneity of lung mononuclear phagocytes in chronic obstructive pulmonar disease","volume":"4","author":"Lee","year":"2012","journal-title":"J. Innate Immun."},{"issue":"1","key":"10.1016\/j.imbio.2022.152194_b0175","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1177\/1040638712466394","article-title":"Value of histopathology, immunohistochemistry, and real-time polymerase chainreaction in the confirmatory diagnosis of Encephalitozoon cuniculi infection in rabbits","volume":"25","author":"Leipig","year":"2013","journal-title":"J. Vet. Diagn. Invest."},{"key":"10.1016\/j.imbio.2022.152194_b0180","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1172\/JCI5212","article-title":"GM-CSF\u2013deficient mice are susceptible to pulmonary group B streptococcal infection","volume":"103","author":"LeVine","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.imbio.2022.152194_b0185","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1128\/iai.62.5.1975-1981.1994","article-title":"Production of tumor necrosis factor alpha in human leukocytes stimulated by Cryptococcus neoformans","volume":"62","author":"Levitz","year":"1994","journal-title":"Infect. Immun."},{"issue":"1","key":"10.1016\/j.imbio.2022.152194_b0190","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1164\/rccm.2008-740ST","article-title":"An official American Thoracic Society statement: treatment of fungal infections in adult pulmonary and critical care patients","volume":"183","author":"Limper","year":"2011","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.imbio.2022.152194_b0195","doi-asserted-by":"crossref","first-page":"847","DOI":"10.2353\/ajpath.2006.050522","article-title":"Compartmentalization of CD4+ T-Cell effector function versus proliferative capacity during pulmonary cryptococcosis","volume":"168","author":"Lindell","year":"2006","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.imbio.2022.152194_b0200","doi-asserted-by":"crossref","first-page":"7389","DOI":"10.4049\/jimmunol.166.12.7389","article-title":"\u03b3\u03b4 T cell-deficient mice have a down-regulated CD8+ T cell immune response against Encephalitozoon cuniculi infection","volume":"166","author":"Moretto","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2022.152194_b0205","doi-asserted-by":"crossref","first-page":"4402","DOI":"10.4049\/jimmunol.172.7.4402","article-title":"Induction of a rapid and strong antigen-specific intraepithelial lymphocyte response during oral Encephalitozoon cuniculi infection","volume":"172","author":"Moretto","year":"2004","journal-title":"J. Immunol."},{"issue":"12","key":"10.1016\/j.imbio.2022.152194_b0210","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1128\/IAI.00820-15","article-title":"Interleukin-12-producing CD103+ CD11b\u2212 CD8+ dendritic cells are responsible for eliciting gut intraepithelial lymphocyte response against Encephalitozoon cuniculi","volume":"83","author":"Moretto","year":"2015","journal-title":"Infect. Immun."},{"key":"10.1016\/j.imbio.2022.152194_b0215","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1080\/01913120590951257","article-title":"Fatal pulmonary microsporidiosis due to Encephalitozoon cuniculi following allogeneic bone marrow transplantation for acute myelogenous leukemia","volume":"29","author":"Orenstein","year":"2005","journal-title":"Ultrastruct. Pathol."},{"issue":"1","key":"10.1016\/j.imbio.2022.152194_b0220","doi-asserted-by":"crossref","first-page":"9","DOI":"10.5578\/tt.10207","article-title":"Evaluation of pulmonary microsporidiosis in iatrogenically immunosuppressed patients","volume":"64","author":"\u00d6zko\u00e7","year":"2016","journal-title":"Tuberk Toraks."},{"issue":"3","key":"10.1016\/j.imbio.2022.152194_b0225","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1128\/JCM.01147-10","article-title":"Unapparent microsporidial infection among immunocompetent humans in the Czech Republic","volume":"49","author":"Sak","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.imbio.2022.152194_b0230","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1182\/blood.V99.4.1246","article-title":"Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage\u2013colony-stimulating factor gene transfer","volume":"99","author":"Santosuosso","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.imbio.2022.152194_b0235","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/BF00436059","article-title":"The relative contribution of resident pulmonary alveolar macrophage and inflammatory polymorphonuclear neutrophils in host resistance to pulmonary infection by Candida albicans","volume":"108","author":"Sawyer","year":"1989","journal-title":"Mycopathol."},{"key":"10.1016\/j.imbio.2022.152194_b0240","doi-asserted-by":"crossref","unstructured":"Scott, J.A., Wonodi, C., Mo\u00efsi, J.C., Deloria-Knoll, M., DeLuca, A.N., Karron, R.A., et al., 2012. The definition of pneumonia, the assessment of severity, and clinical standardization in the Pneumonia Etiology Research for Child Health study. Clin Infect Dis. 54 (Suppl 2), S109\u2013116. doi: 10.1093\/cid\/cir1065. PMID: 22403224; PMCID: PMC3297550.","DOI":"10.1093\/cid\/cir1065"},{"key":"10.1016\/j.imbio.2022.152194_b0245","doi-asserted-by":"crossref","first-page":"353","DOI":"10.4049\/jimmunol.165.1.353","article-title":"CD8+ CTL from Lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages","volume":"165","author":"Serbina","year":"2000","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.imbio.2022.152194_b0250","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1038\/jid.2012.444","article-title":"Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanoma","volume":"133","author":"Sevko","year":"2013","journal-title":"J, Invest. Dermatol."},{"key":"10.1016\/j.imbio.2022.152194_b0255","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s00281-011-0245-0","article-title":"Immunomodulatory effects of cyclophosphamide and implementations for vaccine design","volume":"33","author":"Sistigu","year":"2011","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.imbio.2022.152194_b0260","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/imr.12289","article-title":"Bacterial recognition pathways that lead to inflammasome activation","volume":"265","author":"Storek","year":"2015","journal-title":"Immunol. Rev."},{"issue":"2","key":"10.1016\/j.imbio.2022.152194_b0265","doi-asserted-by":"crossref","first-page":"e55984","DOI":"10.1371\/journal.pone.0055984","article-title":"Dendritic cells are the major antigen presenting cells in inflammatory lesions of murine mycoplasma respiratory disease","volume":"8","author":"Sun","year":"2013","journal-title":"PLoSOne."},{"issue":"2","key":"10.1016\/j.imbio.2022.152194_b0270","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00134-019-05519-y","article-title":"Challenges in severe community-acquired pneumonia: a point-of-view review","volume":"45","author":"Torres","year":"2019","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.imbio.2022.152194_b0275","doi-asserted-by":"crossref","first-page":"7629","DOI":"10.4049\/jimmunol.172.12.7629","article-title":"Accumulation of T Cells in the Lungs and Their Regulatory Roles in Th1 Response and Host Defense against Pulmonary Infection with Cryptococcus neoformans","volume":"172","author":"Uezu","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2022.152194_b0280","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1128\/CMR.15.3.401-413.2002","article-title":"In vitro cultivation of microsporidia of clinical importance","volume":"15","author":"Visvesvara","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.imbio.2022.152194_b0285","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1128\/IAI.00297-09","article-title":"Cytokine signaling regulates the outcome of intracellular macrophage parasitism by Cryptococcus neoformans","volume":"77","author":"Voelz","year":"2009","journal-title":"Infect. Immun."},{"issue":"1","key":"10.1016\/j.imbio.2022.152194_b0290","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/imr.12266","article-title":"Macrophage defense mechanisms against intracellular bacteria","volume":"264","author":"Weiss","year":"2015","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imbio.2022.152194_b0295","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s15010-001-1164-0","article-title":"Dual Microsporidial Infection with Encephalitozoon cuniculi and Enterocytozoon bieneusi in an HIV-Positive Patient","volume":"29","author":"Weitzel","year":"2001","journal-title":"Infect."},{"key":"10.1016\/j.imbio.2022.152194_b0300","unstructured":"World Health Organization WHO Model list of Essential Medicine 2013 http:\/\/www.who.int\/medicines\/publications\/essentialmedicines\/18th_EML.pdf."},{"issue":"2","key":"10.1016\/j.imbio.2022.152194_b0305","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1164\/rccm.200507-1034OC","article-title":"Mast cells protect mice from Mycoplasma pneumonia","volume":"173","author":"Xu","year":"2006","journal-title":"Am. J. Respir. Crit. Care Med."}],"container-title":["Immunobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298522000201?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298522000201?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T16:49:12Z","timestamp":1759250952000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171298522000201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":61,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S0171298522000201"],"URL":"https:\/\/doi.org\/10.1016\/j.imbio.2022.152194","relation":{},"ISSN":["0171-2985"],"issn-type":[{"value":"0171-2985","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Opportunistic pneumonia caused by E. cuniculi in mice immunosuppressed with cyclophosphamide","name":"articletitle","label":"Article Title"},{"value":"Immunobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imbio.2022.152194","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"152194"}}