{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:25:32Z","timestamp":1777861532510,"version":"3.51.4"},"reference-count":63,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["392715"],"award-info":[{"award-number":["392715"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["392711"],"award-info":[{"award-number":["392711"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunobiology"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.imbio.2023.152334","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T12:24:25Z","timestamp":1673267065000},"page":"152334","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Baculovirus-mediated expression of a Helicobacter pylori protein-based multiepitope hybrid gene induces a potent B cell response in mice"],"prefix":"10.1016","volume":"228","author":[{"given":"Ana G.","family":"Montiel-Mart\u00ednez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roxana Y.","family":"Vargas-Jer\u00f3nimo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania","family":"Flores-Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaime","family":"Moreno-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos C.","family":"Bravo-Reyna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ver\u00f3nica","family":"Luque\u00f1o-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariela","family":"Contreras-Escamilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovani","family":"Zamudio-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana","family":"Mart\u00ednez-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Barr\u00e1n-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan C.","family":"Villegas-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Barrios-Pay\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Ruth","family":"Pastor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura A.","family":"Palomares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Esquivel-Guadarrama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efra\u00edn","family":"Garrido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0602-5191","authenticated-orcid":false,"given":"Miguel A.","family":"Torres-Vega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.imbio.2023.152334_b0005","doi-asserted-by":"crossref","first-page":"412","DOI":"10.4292\/wjgpt.v7.i3.412","article-title":"Chinese Helicobacter pylori vaccine: Solution for an old challenge?","volume":"7","author":"Abadi","year":"2016","journal-title":"World J. Gastrointest. Pharmacol. Therapeut."},{"key":"10.1016\/j.imbio.2023.152334_b0010","first-page":"739","article-title":"Baculovirus: An insect-derived vector for diverse gene transfer applications","volume":"Vol. 21(4","author":"Airenne","year":"2013"},{"key":"10.1016\/j.imbio.2023.152334_b0015","unstructured":"Ansari, H., Tahmasebi-Birgani, M., & Bijanzadeh, M. (2021). DNA vaccine containing Flagellin A gene induces significant immune responses against Helicobacter pylori infection: An in vivo study. Iran. J. Basic Med. Sci., 24(6), 796\u2013804. 10.22038\/ijbms.2021.54415.12227."},{"issue":"4","key":"10.1016\/j.imbio.2023.152334_b0020","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/j.molimm.2007.08.010","article-title":"Vaccination of mice with recombinant baculovirus expressing spike or nucleocapsid protein of SARS-like coronavirus generates humoral and cellular immune responses","volume":"45","author":"Bai","year":"2008","journal-title":"Mol. Immunol."},{"issue":"2","key":"10.1016\/j.imbio.2023.152334_b0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003189","article-title":"Functional Plasticity in the Type IV Secretion System of Helicobacter pylori","volume":"9","author":"Barrozo","year":"2013","journal-title":"PLoS Pathog."},{"issue":"4","key":"10.1016\/j.imbio.2023.152334_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.amepre.2020.06.011","article-title":"Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention","volume":"59","author":"Bartsch","year":"2020","journal-title":"Am. J. Prev. Med."},{"issue":"5","key":"10.1016\/j.imbio.2023.152334_b0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0233520","article-title":"Influenza vaccine efficacy induced by orally administered recombinant baculoviruses","volume":"15","author":"Basak","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.imbio.2023.152334_b0040","doi-asserted-by":"crossref","unstructured":"Campestre, C., de Luca, V., Carradori, S., Grande, R., Carginale, V., Scaloni, A., Supuran, C. T., & Capasso, C. (2021). Carbonic Anhydrases: New Perspectives on Protein Functional Role and Inhibition in Helicobacter pylori. In Frontiers in Microbiology (Vol. 12). Frontiers Media S.A. 10.3389\/fmicb.2021.629163.","DOI":"10.3389\/fmicb.2021.629163"},{"issue":"1","key":"10.1016\/j.imbio.2023.152334_b0045","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-020-00618-1","article-title":"Effect of the cagW-based gene vaccine on the immunologic properties of BALB\/c mouse: An efficient candidate for Helicobacter pylori DNA vaccine","volume":"18","author":"Chehelgerdi","year":"2020","journal-title":"J. Nanobiotechnol."},{"issue":"36","key":"10.1016\/j.imbio.2023.152334_b0050","doi-asserted-by":"crossref","first-page":"5310","DOI":"10.1016\/j.vaccine.2012.06.052","article-title":"Therapeutic vaccination with Salmonella-delivered codon-optimized outer inflammatory protein DNA vaccine enhances protection in Helicobacter pylori infected mice","volume":"30","author":"Chen","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.imbio.2023.152334_b0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.coi.2019.12.005","article-title":"Cross-presentation of exogenous antigens on MHC I molecules","volume":"64","author":"Colbert","year":"2020","journal-title":"Curr. Opin. Immunol."},{"issue":"3","key":"10.1016\/j.imbio.2023.152334_b0060","doi-asserted-by":"crossref","first-page":"186","DOI":"10.5306\/wjco.v13.i3.186","article-title":"From Helicobacter pylori infection to gastric cancer: Current evidence on the immune response","volume":"13","author":"de Souza","year":"2022","journal-title":"World J. Clin. Oncol."},{"key":"10.1016\/j.imbio.2023.152334_b0065","doi-asserted-by":"crossref","unstructured":"Debraekeleer, A., & Remaut, H. (2018). Future perspective for potential Helicobacter pylori eradication therapies. In Future Microbiology (Vol. 13, Issue 6, pp. 671\u2013687). Future Medicine Ltd. 10.2217\/fmb-2017-0115.","DOI":"10.2217\/fmb-2017-0115"},{"key":"10.1016\/j.imbio.2023.152334_b0070","doi-asserted-by":"crossref","unstructured":"dos Santos Viana, I., Cordeiro Santos, M. L., Santos Marques, H., Lima de Souza Gon\u00e7alves, V., Bittencourt de Brito, B., Fran\u00e7a da Silva, F. A., Oliveira e Silva, N., Dantas Pinheiro, F., Fernandes Teixeira, A., Tanajura Costa, D., Oliveira Souza, B., Lima Souza, C., Vasconcelos Oliveira, M., & Freire de Melo, F. (2021). Vaccine development against Helicobacter pylori: from ideal antigens to the current landscape. In Expert Review of Vaccines (Vol. 20, Issue 8, pp. 989\u2013999). Taylor and Francis Ltd. 10.1080\/14760584.2021.1945450.","DOI":"10.1080\/14760584.2021.1945450"},{"issue":"6","key":"10.1016\/j.imbio.2023.152334_b0075","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.5604\/01.3001.0012.7203","article-title":"Gene therapy for treatment of chronic hyperammonemia in a rat model of hepatic encephalopathy","volume":"17","author":"Esp\u00edritu-Ram\u00edrez","year":"2018","journal-title":"Ann. Hepatol."},{"issue":"34","key":"10.1016\/j.imbio.2023.152334_b0080","doi-asserted-by":"crossref","first-page":"5124","DOI":"10.1016\/j.vaccine.2018.07.033","article-title":"Immunization with a recombinant fusion protein protects mice against Helicobacter pylori infection","volume":"36","author":"Ghasemi","year":"2018","journal-title":"Vaccine"},{"issue":"6","key":"10.1016\/j.imbio.2023.152334_b0085","doi-asserted-by":"crossref","DOI":"10.1111\/hel.12428","article-title":"Immunologic properties and therapeutic efficacy of a multivalent epitope-based vaccine against four Helicobacter pylori adhesins (urease, Lpp20, HpaA, and CagL) in Mongolian gerbils","volume":"22","author":"Guo","year":"2017","journal-title":"Helicobacter"},{"issue":"MAY","key":"10.1016\/j.imbio.2023.152334_b0090","article-title":"Therapeutic protection against H. pylori infection in Mongolian gerbils by oral immunization with a tetravalent epitope-based vaccine with polysaccharide adjuvant","volume":"10","author":"Guo","year":"2019","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.imbio.2023.152334_b0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0154824","article-title":"Immunogenicity of virus like particle forming baculoviral DNA vaccine against pandemic influenza H1N1","volume":"11","author":"Gwon","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.imbio.2023.152334_b0100","doi-asserted-by":"crossref","unstructured":"Ilic, M., & Ilic, I. (2022). Epidemiology of stomach cancer. In World Journal of Gastroenterology (Vol. 28, Issue 12, pp. 1187\u20131203). Baishideng Publishing Group Inc. 10.3748\/wjg.v28.i12.1187.","DOI":"10.3748\/wjg.v28.i12.1187"},{"issue":"10","key":"10.1016\/j.imbio.2023.152334_b0105","doi-asserted-by":"crossref","DOI":"10.4049\/jimmunol.1501062","article-title":"Helicobacter pylori \u03b3-Glutamyltranspeptidase Induces Tolerogenic Human Dendritic Cells by Activation of Glutamate Receptors","volume":"196","author":"K\u00e4bisch","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.imbio.2023.152334_b0110","doi-asserted-by":"crossref","unstructured":"Keikha, M., Eslami, M., Yousefi, B., Ghasemian, A., & Karbalaei, M. (2019). Potential antigen candidates for subunit vaccine development against Helicobacter pylori infection. In Journal of Cellular Physiology (Vol. 234, Issue 12, pp. 21460\u201321470). Wiley-Liss Inc. 10.1002\/jcp.28870.","DOI":"10.1002\/jcp.28870"},{"key":"10.1016\/j.imbio.2023.152334_b0115","first-page":"791","article-title":"How Helicobacter pylori senses, targets and interacts with the gastric epithelium","volume":"Vol. 18(3","author":"Keilberg","year":"2016"},{"issue":"3","key":"10.1016\/j.imbio.2023.152334_b0120","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1574-695X.2009.00605.x","article-title":"Oral administration of Lactococcus lactis expressing Helicobacter pylori Cag7-ct383 protein induces systemic anti-Cag7 immune response in mice","volume":"57","author":"Kim","year":"2009","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.imbio.2023.152334_b0125","doi-asserted-by":"crossref","unstructured":"Knoll, M. D., & Wonodi, C. (2021). Oxford\u2013AstraZeneca COVID-19 vaccine efficacy. In The Lancet (Vol. 397, Issue 10269). 10.1016\/S0140-6736(20)32623-4.","DOI":"10.1016\/S0140-6736(20)32623-4"},{"issue":"7164","key":"10.1016\/j.imbio.2023.152334_b0130","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/nature06187","article-title":"Helicobacter exploits integrin for type IV secretion and kinase activation","volume":"449","author":"Kwok","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.imbio.2023.152334_b0135","doi-asserted-by":"crossref","unstructured":"Lavelle, E. C., & Ward, R. W. (2022). Mucosal vaccines \u2014 fortifying the frontiers. In Nature Reviews Immunology (Vol. 22, Issue 4, pp. 236\u2013250). Nature Research. 10.1038\/s41577-021-00583-2.","DOI":"10.1038\/s41577-021-00583-2"},{"key":"10.1016\/j.imbio.2023.152334_b0140","doi-asserted-by":"crossref","unstructured":"Lin, C.-Y., Lu, C.-H., Luo, W.-Y., Chang, Y.-H., Sung, L.-Y., Chiu, H.-Y., & Hu, Y.-C. (2010). Baculovirus as a Gene Delivery Vector for Cartilage and Bone Tissue Engineering. In Current Gene Therapy (Vol. 10).","DOI":"10.2174\/156652310791321242"},{"issue":"1","key":"10.1016\/j.imbio.2023.152334_b0145","doi-asserted-by":"crossref","DOI":"10.1038\/s41541-019-0139-z","article-title":"An oral alpha-galactosylceramide adjuvanted Helicobacter pylori vaccine induces protective IL-1R- and IL-17R-dependent Th1 responses","volume":"4","author":"Longet","year":"2019","journal-title":"npj Vaccines"},{"issue":"22","key":"10.1016\/j.imbio.2023.152334_b0150","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.1016\/j.vaccine.2017.03.104","article-title":"Enhancement of VP6 immunogenicity and protective efficacy against rotavirus by VP2 in a genetic immunization","volume":"36","author":"Lopez-Guerrero","year":"2018","journal-title":"Vaccine"},{"issue":"9","key":"10.1016\/j.imbio.2023.152334_b0155","doi-asserted-by":"crossref","first-page":"4965","DOI":"10.1128\/JVI.03510-12","article-title":"Adaptive Immune Responses Elicited by Baculovirus and Impacts on Subsequent Transgene Expression In Vivo","volume":"87","author":"Luo","year":"2013","journal-title":"J. Virol."},{"issue":"9","key":"10.1016\/j.imbio.2023.152334_b0160","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/cgt.2011.35","article-title":"Baculovirus vectors for antiangiogenesis-based cancer gene therapy","volume":"18","author":"Luo","year":"2011","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.imbio.2023.152334_b0165","doi-asserted-by":"crossref","unstructured":"Margulies D. H., Taylor D. K., Jiang, J., Boyd L. F., Ahmad J., Mage M. G., & Natarajan K. Chaperones and Catalysts: How Antigen Presentation Pathways Cope With Biological Necessity. Front Immunol. 2022 Apr 7;13:859782. doi: 10.3389\/fimmu.2022.859782. eCollection 2022.","DOI":"10.3389\/fimmu.2022.859782"},{"issue":"2","key":"10.1016\/j.imbio.2023.152334_b0170","doi-asserted-by":"crossref","DOI":"10.2144\/03342bm05","article-title":"Titration of non-occluded baculovirus using a cell viability assay","volume":"34","author":"Mena","year":"2003","journal-title":"Biotechniques"},{"key":"10.1016\/j.imbio.2023.152334_b0175","doi-asserted-by":"crossref","unstructured":"Mirzaei, N., Poursina, F., Moghim, S., Rashidi, N., & Ghasemian Safaei, H. (2017). The study of H. pylori putative candidate factors for single- and multi-component vaccine development. In Critical Reviews in Microbiology (Vol. 43, Issue 5, pp. 631\u2013650). Taylor and Francis Ltd. 10.1080\/1040841X.2017.1291578.","DOI":"10.1080\/1040841X.2017.1291578"},{"key":"10.1016\/j.imbio.2023.152334_b0180","first-page":"MDPI","article-title":"Clinical relevance of helicobacter pylori infection. In Journal of","volume":"Vol. 10, Issue 16","author":"Mladenova","year":"2021","journal-title":"Clin. Med."},{"key":"10.1016\/j.imbio.2023.152334_b0185","article-title":"Systematic review of time trends in the prevalence of Helicobacter pylori infection in China and the USA","volume":"8, Issue 1)","author":"Nagy","year":"2016","journal-title":"In Gut Pathogens (Vol."},{"issue":"MAY","key":"10.1016\/j.imbio.2023.152334_b0190","article-title":"Identification of two Lpp20 CD4+ T cell epitopes in Helicobacter pylori-infected subjects","volume":"9","author":"Ning","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.imbio.2023.152334_b0200","first-page":"267","article-title":"Mechanisms of inflammasome signaling, microRNA induction and resolution of inflammation by helicobacter pylori","volume":"Vol. 421","author":"Pachathundikandi","year":"2019"},{"issue":"MAY","key":"10.1016\/j.imbio.2023.152334_b0205","article-title":"Protection against Helicobacter pylori Infection in BALB\/c mouse model by oral administration of multivalent epitope-based vaccine of cholera toxin B Subunit-HUUC","volume":"9","author":"Pan","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.imbio.2023.152334_bib316","unstructured":"Parikh, N.S., Ahlawat, R., 2022. Helicobacter Pylori. 2022 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. PMID: 30480966."},{"key":"10.1016\/j.imbio.2023.152334_b0210","doi-asserted-by":"crossref","unstructured":"Peleteiro, B., Bastos, A., Ferro, A., & Lunet, N. (2014). Prevalence of Helicobacter pylori infection worldwide: A systematic review of studies with national coverage. In Digestive Diseases and Sciences (Vol. 59, Issue 8). 10.1007\/s10620-014-3063-0.","DOI":"10.1007\/s10620-014-3063-0"},{"key":"10.1016\/j.imbio.2023.152334_b0215","doi-asserted-by":"crossref","unstructured":"Pieroni, L., Maione, D., & Monica, N. la. (2001). In Vivo Gene Transfer in Mouse Skeletal Muscle Mediated by Baculovirus Vectors. In HUMAN GENE THERAPY (Vol. 12). Mary Ann Liebert, Inc.","DOI":"10.1089\/104303401750195845"},{"key":"10.1016\/j.imbio.2023.152334_b0220","article-title":"A guide to vaccinology: from basic principles to new developments. In","volume":"Vol. 21, Issue 2","author":"Pollard","year":"2021","journal-title":"Nat. Rev. Immunol."},{"issue":"9","key":"10.1016\/j.imbio.2023.152334_b0225","doi-asserted-by":"crossref","DOI":"10.1128\/CVI.00251-13","article-title":"Long-term protective immunity from an influenza virus-like particle vaccine administered with a microneedle patch","volume":"20","author":"Quan","year":"2013","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.imbio.2023.152334_b0230","author":"Robinson","year":"2021","journal-title":"The Spectrum of Helicobacter-Mediated Diseases."},{"issue":"4","key":"10.1016\/j.imbio.2023.152334_b0235","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nri3818","article-title":"The ins and outs of MHC class II-mediated antigen processing and presentation","volume":"15","author":"Roche","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.imbio.2023.152334_b0240","first-page":"115","article-title":"Baculoviruses in gene therapy and personalized medicine","volume":"Vol. 15","author":"Schaly","year":"2021"},{"key":"10.1016\/j.imbio.2023.152334_b0245","doi-asserted-by":"crossref","unstructured":"Sharndama, H. C., & Mba, I. E. (2022). Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms. In Brazilian Journal of Microbiology (Vol. 53, Issue 1, pp. 33\u201350). Springer Science and Business Media Deutschland GmbH. 10.1007\/s42770-021-00675-0.","DOI":"10.1007\/s42770-021-00675-0"},{"key":"10.1016\/j.imbio.2023.152334_b0250","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2020.01551","article-title":"Defining the Helicobacter pylori Disease-Specific Antigenic Repertoire","volume":"11","author":"Soluri","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.imbio.2023.152334_b0255","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2020.01340","article-title":"Outer Membrane Vesicles of Helicobacter pylori 7.13 as Adjuvants Promote Protective Efficacy Against Helicobacter pylori Infection","volume":"11","author":"Song","year":"2020","journal-title":"Front. Microbiol."},{"issue":"12","key":"10.1016\/j.imbio.2023.152334_b0260","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1007\/s10529-019-02740-z","article-title":"A food-grade engineered Lactococcus lactis strain delivering Helicobacter pylori Lpp20 alleviates bacterial infection in H. pylori-challenged mice","volume":"41","author":"Sun","year":"2019","journal-title":"Biotechnol. Lett"},{"key":"10.1016\/j.imbio.2023.152334_b0265","doi-asserted-by":"crossref","unstructured":"Targovnik, A. M., Simonin, J. A., Mc Callum, G. J., Smith, I., Cuccovia Warlet, F. U., Nugnes, M. V., Miranda, M. V., & Belaich, M. N. (2021). Solutions against emerging infectious and noninfectious human diseases through the application of baculovirus technologies. In Applied Microbiology and Biotechnology (Vol. 105, Issues 21\u201322, pp. 8195\u20138226). Springer Science and Business Media Deutschland GmbH. 10.1007\/s00253-021-11615-1.","DOI":"10.1007\/s00253-021-11615-1"},{"issue":"1","key":"10.1016\/j.imbio.2023.152334_b0270","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/gt.2014.89","article-title":"Delivery of glutamine synthetase gene by baculovirus vectors: A proof of concept for the treatment of acute hyperammonemia","volume":"22","author":"Torres-Vega","year":"2015","journal-title":"Gene Ther."},{"key":"10.1016\/j.imbio.2023.152334_b0275","doi-asserted-by":"crossref","unstructured":"Tshibangu-Kabamba, E., & Yamaoka, Y. (2021). Helicobacter pylori infection and antibiotic resistance \u2014 from biology to clinical implications. In Nature Reviews Gastroenterology and Hepatology (Vol. 18, Issue 9, pp. 613\u2013629). Nature Research. 10.1038\/s41575-021-00449-x.","DOI":"10.1038\/s41575-021-00449-x"},{"issue":"16","key":"10.1016\/j.imbio.2023.152334_b0280","doi-asserted-by":"crossref","DOI":"10.1089\/10430340260355347","article-title":"Insect cells as a factory to produce adeno-associated virus type 2 vectors","volume":"13","author":"Urabe","year":"2002","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.imbio.2023.152334_b0285","unstructured":"Zarei, M., Mosayebi, G., Khansarinejad, B., & Abtahi, H. (2017). Antigenic and immunogenic evaluation of helicobacter pylori flaa epitopes. Iranian Journal of Basic Medical Sciences, 20(8), 920\u2013926. 10.22038\/ijbms.2017.9115."},{"issue":"10002","key":"10.1016\/j.imbio.2023.152334_b0290","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/S0140-6736(15)60310-5","article-title":"Efficacy, safety, and immunogenicity of an oral recombinant Helicobacter pylori vaccine in children in China: a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"386","author":"Zeng","year":"2015","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.imbio.2023.152334_b0295","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130391","article-title":"Immunization with heat shock protein A and \u03b3-Glutamyl transpeptidase induces reduction on the helicobacter pylori colonization in mice","volume":"10","author":"Zhang","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.imbio.2023.152334_b0300","first-page":"1","article-title":"Mechanisms of persistence, innate immune activation and immunomodulation by the gastric pathogen Helicobacter pylori","volume":"Vol. 54","author":"Zhang","year":"2020"},{"key":"10.1016\/j.imbio.2023.152334_b0305","doi-asserted-by":"crossref","unstructured":"Zhang, Q., Wu, W., Zhang, J., & Xia, X. (2020). Eradication of Helicobacter pylori: The power of nanosized formulations. In Nanomedicine (Vol. 15, Issue 5, pp. 527\u2013542). Future Medicine Ltd. 10.2217\/nnm-2019-0329.","DOI":"10.2217\/nnm-2019-0329"},{"issue":"3","key":"10.1016\/j.imbio.2023.152334_b0310","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s10529-017-2502-3","article-title":"Delivery of Helicobacter pylori HpaA to gastrointestinal mucosal immune sites using Lactococcus lactis and its immune efficacy in mice","volume":"40","author":"Zhang","year":"2018","journal-title":"Biotechnol. Lett"},{"key":"10.1016\/j.imbio.2023.152334_b0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104229","article-title":"Oral immunization of BALB\/c mice with recombinant Helicobacter pylori antigens and double mutant heat-labile toxin (dmLT) induces prophylactic protective immunity against H. pylori infection","volume":"145","author":"Zhong","year":"2020","journal-title":"Microb. Pathog."}],"container-title":["Immunobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298523000025?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298523000025?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:23:34Z","timestamp":1777523014000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171298523000025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":63,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S0171298523000025"],"URL":"https:\/\/doi.org\/10.1016\/j.imbio.2023.152334","relation":{},"ISSN":["0171-2985"],"issn-type":[{"value":"0171-2985","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Baculovirus-mediated expression of a Helicobacter pylori protein-based multiepitope hybrid gene induces a potent B cell response in mice","name":"articletitle","label":"Article Title"},{"value":"Immunobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imbio.2023.152334","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"152334"}}