{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:21:13Z","timestamp":1786990873077,"version":"build-2736575974"},"reference-count":16,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.imlet.2005.06.004","type":"journal-article","created":{"date-parts":[[2005,7,13]],"date-time":"2005-07-13T15:40:17Z","timestamp":1121269217000},"page":"226-230","source":"Crossref","is-referenced-by-count":128,"title":["Activated inflammatory T cells correlate with lesion size in human cutaneous leishmaniasis"],"prefix":"10.1016","volume":"101","author":[{"given":"Lis R.V.","family":"Antonelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walderez O.","family":"Dutra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roque P.","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Bacellar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar M.","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J.","family":"Gollob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2005.06.004_bib1","doi-asserted-by":"crossref","first-page":"651","DOI":"10.4269\/ajtmh.1997.57.651","article-title":"A low-dose antimony treatment in 159 patients with American cutaneous leishmaniasis: extensive follow-up studies (up to 10 years)","volume":"57","author":"Oliveira-Neto","year":"1997","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.imlet.2005.06.004_bib2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0165-2478(98)00131-X","article-title":"Immune effector mechanism in parasitic infections","volume":"65","author":"Liew","year":"1999","journal-title":"Immunol Lett"},{"key":"10.1016\/j.imlet.2005.06.004_bib3","doi-asserted-by":"crossref","first-page":"5858","DOI":"10.4049\/jimmunol.164.11.5858","article-title":"IL-12p70 production by Leishmania major-harboring human dendritic cells is a CD40\/CD40 ligand-dependent process","volume":"164","author":"Marovich","year":"2000","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2005.06.004_bib4","doi-asserted-by":"crossref","first-page":"6734","DOI":"10.1128\/IAI.70.12.6734-6740.2002","article-title":"Up-regulation of Th1-type responses in mucosal leishmaniasis patients","volume":"70","author":"Bacellar","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2005.06.004_bib5","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1365-2249.2004.02426.x","article-title":"Antigen specific correlations of cellular immune responses in human leishmaniasis suggests mechanisms for immunoregulation","volume":"136","author":"Antonelli","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.imlet.2005.06.004_bib6","unstructured":"Guedes C, Cuce L, Furtado T. Avaliacao imunologica e histopatologica da reacao de Montenegro. In: An Brasil de Dermatologia. 66 ed.; 1990, p. 34S\u201340S."},{"key":"10.1016\/j.imlet.2005.06.004_bib7","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1080\/00034983.1985.11811917","article-title":"An experimental vaccine against American dermal leishmaniasis: experience in the State of Espirito Santo, Brazil","volume":"79","author":"Mayrink","year":"1985","journal-title":"Ann Trop Med Parasitol"},{"key":"10.1016\/j.imlet.2005.06.004_bib8","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.1128\/IAI.69.5.3232-3239.2001","article-title":"Flow cytometric determination of cellular sources and frequencies of key cytokine-producing lymphocytes directed against recombinant LACK and soluble Leishmania antigen in human cutaneous leishmaniasis","volume":"69","author":"Bottrel","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2005.06.004_bib9","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1590\/S0036-46651989000400008","article-title":"Histological observations on Montenegro's reaction in man","volume":"31","author":"Mayrink","year":"1989","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"10.1016\/j.imlet.2005.06.004_bib10","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1046\/j.1365-3156.1997.d01-236.x","article-title":"The epidemiology of cutaneous leishmaniasis in subtropical Ecuador","volume":"2","author":"Armijos","year":"1997","journal-title":"Trop Med Int Health"},{"key":"10.1016\/j.imlet.2005.06.004_bib11","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1046\/j.1365-3024.2002.00488.x","article-title":"Endemically exposed asymptomatic individuals show no increase in the specific Leishmania (Viannia) panamensis-Th1 immune response in comparison to patients with localized cutaneous leishmaniasis","volume":"24","author":"Trujillo","year":"2002","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.imlet.2005.06.004_bib12","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1128\/IAI.62.6.2614-2618.1994","article-title":"Leishmania-reactive CD4+ and CD8+ T cells associated with cure of human cutaneous leishmaniasis","volume":"62","author":"Da-Cruz","year":"1994","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2005.06.004_bib13","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/nature01152","article-title":"CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity","volume":"420","author":"Belkaid","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.imlet.2005.06.004_bib14","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1086\/315071","article-title":"Down-regulation of Th1 type of response in early human American cutaneous leishmaniasis","volume":"180","author":"Rocha","year":"1999","journal-title":"J Infect Dis"},{"key":"10.1016\/j.imlet.2005.06.004_bib15","doi-asserted-by":"crossref","first-page":"6734","DOI":"10.1128\/IAI.70.12.6734-6740.2002","article-title":"Up-regulation of Th1-type responses in mucosal leishmaniasis patients","volume":"70","author":"Bacellar","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2005.06.004_bib16","doi-asserted-by":"crossref","first-page":"2821","DOI":"10.4049\/jimmunol.163.5.2821","article-title":"Altered immune responses and susceptibility to Leishmania major and Staphylococcus aureus infection in IL-18-deficient mice","volume":"163","author":"Wei","year":"1999","journal-title":"J Immunol"}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247805001410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247805001410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T14:57:03Z","timestamp":1683125823000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247805001410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0165247805001410"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2005.06.004","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]}}}