{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:01:37Z","timestamp":1744156897044},"reference-count":46,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1016\/j.imlet.2007.04.010","type":"journal-article","created":{"date-parts":[[2007,5,24]],"date-time":"2007-05-24T07:39:32Z","timestamp":1179992372000},"page":"26-35","source":"Crossref","is-referenced-by-count":21,"title":["Mucosal prime-boost vaccination for tuberculosis based on TLR triggering OprI lipoprotein from Pseudomonas aeruginosa fused to mycolyl-transferase Ag85A"],"prefix":"10.1016","volume":"111","author":[{"given":"Tatiana","family":"Gartner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martijn","family":"Baeten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Otieno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilde","family":"Revets","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"De Baetselier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kris","family":"Huygen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2007.04.010_bib1","unstructured":"WHO. http:\/\/www.who.int\/mediacentre\/factsheets\/fs104\/en; 2004."},{"key":"10.1016\/j.imlet.2007.04.010_bib2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1146\/annurev.publhealth.23.100901.140519","volume":"23","author":"Tiruviluamala","year":"2002","journal-title":"Annu Rev Public Health"},{"key":"10.1016\/j.imlet.2007.04.010_bib3","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/nrmicro1419","article-title":"Advances in tuberculosis vaccine strategies","volume":"4","author":"Skeiky","year":"2006","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.imlet.2007.04.010_bib4","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/nri1920","article-title":"Envisioning future strategies for vaccination against tuberculosis","volume":"6","author":"Kaufmann","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib5","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.4049\/jimmunol.171.3.1602","article-title":"Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guerin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus Ankara","volume":"171","author":"Goonetilleke","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib6","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1128\/IAI.72.1.238-246.2004","article-title":"Single intranasal mucosal Mycobacterium bovis BCG vaccination confers improved protection compared to subcutaneous vaccination against pulmonary tuberculosis","volume":"72","author":"Chen","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib7","doi-asserted-by":"crossref","first-page":"7986","DOI":"10.4049\/jimmunol.174.12.7986","article-title":"Mechanisms of mucosal and parenteral tuberculosis vaccinations: adenoviral-based mucosal immunization preferentially elicits sustained accumulation of immune protective CD4 and CD8 T cells within the airway lumen","volume":"174","author":"Santosuosso","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib8","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S1286-4579(03)00013-3","article-title":"Regulation of the generation and maintenance of T-cell memory: a direct, default pathway from effectors to memory cells","volume":"5","author":"Swain","year":"2003","journal-title":"Microbes Infect"},{"key":"10.1016\/j.imlet.2007.04.010_bib9","doi-asserted-by":"crossref","first-page":"7759","DOI":"10.1128\/IAI.73.11.7759-7764.2005","article-title":"Memory T lymphocytes generated by Mycobacterium bovis BCG vaccination reside within a CD4 CD44lo CD62 Ligandhi population","volume":"73","author":"Kipnis","year":"2005","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib10","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/ni832","article-title":"Distinct lineages of T(H)1 cells have differential capacities for memory cell generation in vivo","volume":"3","author":"Wu","year":"2002","journal-title":"Nat Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib11","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1016\/j.vaccine.2005.12.066","article-title":"Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv","volume":"24","author":"Romano","year":"2006","journal-title":"Vaccine"},{"key":"10.1016\/j.imlet.2007.04.010_bib12","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.4049\/jimmunol.174.2.1097","article-title":"Lipoprotein I, a TLR2\/4 ligand modulates Th2-driven allergic immune responses","volume":"174","author":"Revets","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib13","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1128\/IAI.70.1.240-248.2002","article-title":"Bacterial lipoprotein-based vaccines induce tumor necrosis factor-dependent type 1 protective immunity against Leishmania major","volume":"70","author":"Cote-Sierra","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib14","doi-asserted-by":"crossref","first-page":"4757","DOI":"10.1016\/j.vaccine.2006.03.028","article-title":"Efficacy and functionality of lipoprotein OprI from Pseudomonas aeruginosa as adjuvant for a subunit vaccine against classical swine fever","volume":"24","author":"Rau","year":"2006","journal-title":"Vaccine"},{"key":"10.1016\/j.imlet.2007.04.010_bib15","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/72413","article-title":"Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines","volume":"7","author":"Ronning","year":"2000","journal-title":"Nat Struct Biol"},{"key":"10.1016\/j.imlet.2007.04.010_bib16","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1128\/MMBR.56.4.648-661.1992","article-title":"The antigen 85 complex: a major secretion product of Mycobacterium tuberculosis","volume":"56","author":"Wiker","year":"1992","journal-title":"Microbiol Rev"},{"key":"10.1016\/j.imlet.2007.04.010_bib17","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1128\/IAI.66.6.2951-2959.1998","article-title":"Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis","volume":"66","author":"Baldwin","year":"1998","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib18","doi-asserted-by":"crossref","first-page":"4174","DOI":"10.1128\/IAI.69.6.4174-4176.2001","article-title":"Priming by DNA immunization augments protective efficacy of Mycobacterium bovis bacille Calmette-Guerin against tuberculosis","volume":"69","author":"Feng","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib19","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1038\/nm0896-893","article-title":"Immunogenicity and protective efficacy of a tuberculosis DNA vaccine","volume":"2","author":"Huygen","year":"1996","journal-title":"Nat Med"},{"key":"10.1016\/j.imlet.2007.04.010_bib20","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1086\/425931","article-title":"Comparative analysis of different vaccine constructs expressing defined antigens from Mycobacterium tuberculosis","volume":"190","author":"Doherty","year":"2004","journal-title":"J Infect Dis"},{"key":"10.1016\/j.imlet.2007.04.010_bib21","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1038\/nm1128","article-title":"Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans","volume":"10","author":"McShane","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.imlet.2007.04.010_bib22","doi-asserted-by":"crossref","first-page":"4634","DOI":"10.1128\/IAI.00517-06","article-title":"Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosis","volume":"74","author":"Santosuosso","year":"2006","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib23","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1128\/IAI.69.4.2714-2717.2001","article-title":"Boosting vaccine for tuberculosis","volume":"69","author":"Brooks","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib24","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.1128\/IAI.69.5.3041-3047.2001","article-title":"Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting","volume":"69","author":"Tanghe","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib25","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0378-1119(98)00437-5","article-title":"A new membrane-bound OprI lipoprotein expression vector. High production of heterologous fusion proteins in Gram (\u2212) bacteria and the implications for oral vaccination","volume":"221","author":"Cote-Sierra","year":"1998","journal-title":"Gene"},{"key":"10.1016\/j.imlet.2007.04.010_bib26","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nbt0296-203","article-title":"Development of new cloning vectors for the production of immunogenic outer membrane fusion proteins in Escherichia coli","volume":"14","author":"Cornelis","year":"1996","journal-title":"Biotechnology (NY)"},{"key":"10.1016\/j.imlet.2007.04.010_bib27","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1365-2958.1989.tb00187.x","article-title":"Cloning and analysis of the gene for the major outer membrane lipoprotein from Pseudomonas aeruginosa","volume":"3","author":"Cornelis","year":"1989","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.imlet.2007.04.010_bib28","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1128\/IAI.66.4.1527-1533.1998","article-title":"Vaccination with plasmid DNA encoding mycobacterial antigen 85A stimulates a CD4+ and CD8+ T-cell epitopic repertoire broader than that stimulated by Mycobacterium tuberculosis H37Rv infection","volume":"66","author":"Denis","year":"1998","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib29","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0882-4010(87)90077-5","article-title":"Purification, characterization and identification of a 32kDa protein antigen of Mycobacterium bovis BCG","volume":"2","author":"De Bruyn","year":"1987","journal-title":"Microb Pathog"},{"key":"10.1016\/j.imlet.2007.04.010_bib30","doi-asserted-by":"crossref","first-page":"2880","DOI":"10.1128\/IAI.60.7.2880-2886.1992","article-title":"Spleen cell cytokine secretion in Mycobacterium bovis BCG-infected mice","volume":"60","author":"Huygen","year":"1992","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib31","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1128\/IAI.71.1.483-493.2003","article-title":"Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis","volume":"71","author":"D'Souza","year":"2003","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib32","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1128\/IAI.62.2.363-370.1994","article-title":"Mapping of TH1 helper T-cell epitopes on major secreted mycobacterial antigen 85A in mice infected with live Mycobacterium bovis BCG","volume":"62","author":"Huygen","year":"1994","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib33","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.4049\/jimmunol.162.2.1113","article-title":"Immunogenicity and protective efficacy of tuberculosis DNA vaccines encoding putative phosphate transport receptors","volume":"162","author":"Tanghe","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib34","doi-asserted-by":"crossref","first-page":"6308","DOI":"10.4049\/jimmunol.174.10.6308","article-title":"The mucosal adjuvant macrophage-activating lipopeptide-2 directly stimulates B lymphocytes via the TLR2 without the need of accessory cells","volume":"174","author":"Borsutzky","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib35","doi-asserted-by":"crossref","first-page":"6639","DOI":"10.4049\/jimmunol.174.11.6639","article-title":"Role of TLR in B cell development: signaling through TLR4 promotes B cell maturation and is inhibited by TLR2","volume":"174","author":"Hayashi","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinf.2005.12.017","article-title":"Protective efficacy of intranasal vaccination with Mycobacterium bovis BCG against airway Mycobacterium tuberculosis challenge in mice","author":"Giri","year":"2006","journal-title":"J Infect"},{"key":"10.1016\/j.imlet.2007.04.010_bib37","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.1128\/IAI.68.10.5657-5662.2000","article-title":"Mycobacterium bovis BCG induces similar immune responses and protection by rectal and parenteral immunization routes","volume":"68","author":"Abolhassani","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib38","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/S0264-410X(99)00386-2","article-title":"Immunogenicity and protective capacity of Mycobacterium bovis BCG after oral or intragastric administration in mice","volume":"18","author":"Lagranderie","year":"2000","journal-title":"Vaccine"},{"key":"10.1016\/j.imlet.2007.04.010_bib39","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1365-2249.2004.02648.x","article-title":"Intranasal bacille Calmette-Guerin (BCG) vaccine dosage needs balancing between protection and lung pathology","volume":"138","author":"Tree","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib40","doi-asserted-by":"crossref","first-page":"6357","DOI":"10.4049\/jimmunol.173.10.6357","article-title":"Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis","volume":"173","author":"Wang","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib41","doi-asserted-by":"crossref","first-page":"6622","DOI":"10.1128\/IAI.72.11.6622-6632.2004","article-title":"The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs","volume":"72","author":"Brandt","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib42","doi-asserted-by":"crossref","first-page":"6353","DOI":"10.4049\/jimmunol.177.9.6353","article-title":"Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity","volume":"177","author":"Dietrich","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib43","article-title":"The combined CTA1-DD\/ISCOMs vector is an effective intranasal adjuvant for boosting prior BCG immunity to Mycobacterium tuberculosis","author":"Andersen","year":"2006","journal-title":"Infect Immun"},{"key":"10.1016\/j.imlet.2007.04.010_bib44","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1146\/annurev.immunol.20.081501.125851","article-title":"Genetic dissection of immunity to mycobacteria: the human model","volume":"20","author":"Casanova","year":"2002","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.imlet.2007.04.010_bib45","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1084\/jem.178.6.2243","article-title":"Disseminated tuberculosis in interferon gamma gene-disrupted mice","volume":"178","author":"Cooper","year":"1993","journal-title":"J Exp Med"},{"key":"10.1016\/j.imlet.2007.04.010_bib46","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.vaccine.2004.11.010","article-title":"Mucosal adjuvants","volume":"23","author":"Freytag","year":"2005","journal-title":"Vaccine"}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247807000818?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247807000818?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T23:46:29Z","timestamp":1683848789000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247807000818"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["S0165247807000818"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2007.04.010","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}