{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T04:02:24Z","timestamp":1778126544359,"version":"3.51.4"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1016\/j.imlet.2008.10.002","type":"journal-article","created":{"date-parts":[[2008,11,5]],"date-time":"2008-11-05T11:02:21Z","timestamp":1225882941000},"page":"134-139","source":"Crossref","is-referenced-by-count":26,"title":["Increased bone resorption and osteopenia are a part of the lymphoproliferative phenotype of mice with systemic over-expression of interleukin-7 gene driven by MHC class II promoter"],"prefix":"10.1016","volume":"121","author":[{"given":"Daniela","family":"Salopek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danka","family":"Gr\u010devi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vedran","family":"Katavi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nata\u0161a","family":"Kova\u010di\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan Kre\u0161imir","family":"Luki\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Maru\u0161i\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2008.10.002_bib1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/cmi.2008.10","article-title":"Interleukin-7 receptor signaling network: an integrated systems perspective","volume":"2","author":"Palmer","year":"2008","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib2","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/eji.1830210230","article-title":"Development of lymphocytes in interleukin 7-transgenic mice","volume":"21","author":"Samaridis","year":"1991","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib3","first-page":"66","article-title":"Lymphoproliferative disorders in an IL-7 transgenic mouse line","volume":"2","author":"Fisher","year":"1993","journal-title":"Leukemia"},{"key":"10.1016\/j.imlet.2008.10.002_bib4","doi-asserted-by":"crossref","first-page":"3524","DOI":"10.1210\/en.2002-221057","article-title":"Interleukin-7 is a direct inhibitor of in vitro osteoclastogenesis","volume":"144","author":"Lee","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.imlet.2008.10.002_bib5","doi-asserted-by":"crossref","first-page":"9360","DOI":"10.1073\/pnas.94.17.9360","article-title":"Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: similarity to estrogen deficiency","volume":"94","author":"Miyaura","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.imlet.2008.10.002_bib6","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1172\/JCI15687","article-title":"Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency","volume":"110","author":"Weitzmann","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1016\/j.imlet.2008.10.002_bib7","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1359\/jbmr.060117","article-title":"Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss","volume":"23","author":"Lee","year":"2006","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.imlet.2008.10.002_bib8","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.0105-2896.2005.00339.x","article-title":"Role of interleukin-7 in bone and T-cell homeostasis","volume":"208","author":"Lee","year":"2005","journal-title":"Immunol Rev"},{"key":"10.1016\/j.imlet.2008.10.002_bib9","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3109\/08830189809042998","article-title":"Interleukin-7, a non-redundant potent cytokine whose over-expression massively perturbs B-lymphopoiesis","volume":"16","author":"Mertsching","year":"1998","journal-title":"Int Rev Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib10","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.4049\/jimmunol.179.3.1549","article-title":"Regulation of MHC class II expression and antigen processing in murine and human mesenchymal stromal cells by IFN-gamma, TGF-beta, and cell density","volume":"179","author":"Romieu-Mourez","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib11","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S8756-3282(03)00097-8","article-title":"The surface antigen CD45R identifies a population of estrogen-regulated murine marrow cells that contain osteoclast precursors","volume":"32","author":"Katavic","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.imlet.2008.10.002_bib12","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.4049\/jimmunol.170.3.1540","article-title":"Increased bone mass is a part of the generalized lymphoproliferative disorder phenotype in the mouse","volume":"170","author":"Katavic","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib13","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1365-2249.2006.03181.x","article-title":"Activated T lymphocytes suppress osteoclastogenesis by diverting early monocyte\/macrophage progenitor lineage commitment towards dendritic cell differentiation through down-regulation of receptor activator of nuclear factor-kappaB and c-Fos","volume":"146","author":"Grcevic","year":"2006","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib14","doi-asserted-by":"crossref","first-page":"3379","DOI":"10.4049\/jimmunol.178.6.3379","article-title":"The Fas\/Fas ligand system inhibits differentiation of murine OBLs but has a limited role in OBL and osteoclast apoptosis","volume":"178","author":"Kovacic","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib15","doi-asserted-by":"crossref","first-page":"4231","DOI":"10.4049\/jimmunol.165.8.4231","article-title":"Depletion of CD4 and CD8 T lymphocytes in mice in vivo enhances 1,25-dihydroxyvitamin D3-stimulated osteoclast-like cell formation in vitro by a mechanism that is dependent on prostaglandin synthesis","volume":"165","author":"Grcevic","year":"2000","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib16","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.4049\/jimmunol.149.4.1276","article-title":"Administration of human recombinant IL-7 to normal and irradiated mice increases the numbers of lymphocytes and some immature cells of the myeloid lineage","volume":"149","author":"Faltynek","year":"1992","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2008.10.002_bib17","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1210\/er.2007-0038","article-title":"Osteoimmunology: interactions of the bone and immune system","volume":"29","author":"Lorenzo","year":"2008","journal-title":"Endocr Rev"},{"key":"10.1016\/j.imlet.2008.10.002_bib18","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00774-006-0723-y","article-title":"Production of IL-7 is increased in ovariectomized mice, but not RANKL mRNA expression by OBLs\/stromal cells in bone, and IL-7 enhances generation of osteoclast precursors in vitro","volume":"25","author":"Sato","year":"2007","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.imlet.2008.10.002_bib19","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1073\/pnas.0136772100","article-title":"IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor \u03baB ligand and tumor necrosis factor \u03b1 from T cells","volume":"100","author":"Toraldo","year":"2003","journal-title":"PNAS"},{"key":"10.1016\/j.imlet.2008.10.002_bib20","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1359\/jbmr.2001.16.12.2215","article-title":"Generation of bone-resorbing osteoclasts from B220+ cells: its role in accelerated osteoclastogenesis due to estrogen deficiency","volume":"16","author":"Sato","year":"2001","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.imlet.2008.10.002_bib21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1359\/JBMR.051007","article-title":"Identification of multiple osteoclast precursor population in murine bone marrow","volume":"21","author":"Jacquin","year":"2006","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.imlet.2008.10.002_bib22","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1084\/jem.191.1.5","article-title":"The development of B cells in the bone marrow is controlled by the balance between cell-autonomous mechanisms and signals from the microenvironment","volume":"191","author":"Carsetti","year":"2000","journal-title":"J Exp Med"},{"key":"10.1016\/j.imlet.2008.10.002_bib23","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1182\/blood-2002-01-0062","article-title":"Functional interleukin-7 receptors (IL-7Rs) are expressed by marrow stromal cells: binding of IL-7 increases levels of IL-6 mRNA and secreted protein","volume":"100","author":"Iwata","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2008.10.002_bib24","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/01.bor.0000231913.32364.32","article-title":"Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease","volume":"18","author":"Boyce","year":"2006","journal-title":"Curr Opin Rheumatol"}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247808002241?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247808002241?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:50:41Z","timestamp":1684619441000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247808002241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["S0165247808002241"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2008.10.002","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2008,12]]}}}