{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:54:56Z","timestamp":1761540896358},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.imlet.2008.12.008","type":"journal-article","created":{"date-parts":[[2009,1,29]],"date-time":"2009-01-29T09:16:17Z","timestamp":1233220577000},"page":"185-192","source":"Crossref","is-referenced-by-count":9,"title":["Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia"],"prefix":"10.1016","volume":"122","author":[{"given":"Karel","family":"Svojgr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"Burjanivova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Vaskova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomas","family":"Kalina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Stary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Trka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Zuna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2008.12.008_bib1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/nri1414","article-title":"Transmembrane adaptor proteins: organizers of immunoreceptor signalling","volume":"4","author":"Horejsi","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.imlet.2008.12.008_bib2","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/nrm1925","article-title":"Lipid rafts: contentious only from simplistic standpoints","volume":"7","author":"Hancock","year":"2006","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.imlet.2008.12.008_bib3","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1084\/jem.191.9.1591","article-title":"Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase Csk and is involved in regulation of T cell activation","volume":"191","author":"Brdicka","year":"2000","journal-title":"J Exp Med"},{"key":"10.1016\/j.imlet.2008.12.008_bib4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.imlet.2003.10.013","article-title":"Transmembrane adaptor proteins in membrane microdomains: important regulators of immunoreceptor signaling","volume":"92","author":"Horejsi","year":"2004","journal-title":"Immunol Lett"},{"key":"10.1016\/j.imlet.2008.12.008_bib5","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/eji.200636664","article-title":"A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration","volume":"38","author":"Posevitz-Fejfar","year":"2008","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.imlet.2008.12.008_bib6","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1182\/blood-2006-07-038752","article-title":"A novel negative regulatory function of the phosphoprotein associated with glycosphingolipid-enriched microdomains: blocking Ras activation","volume":"110","author":"Smida","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2008.12.008_bib7","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.imlet.2005.05.002","article-title":"Expression pattern of adaptor protein PAG: correlation between secondary lymphatic follicle and histogenetically related malignant lymphomas","volume":"100","author":"Svec","year":"2005","journal-title":"Immunol Lett"},{"key":"10.1016\/j.imlet.2008.12.008_bib8","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1182\/blood-2002-02-0456","article-title":"Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes","volume":"101","author":"Baumgartner","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2008.12.008_bib9","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S1074-7613(00)80032-1","article-title":"Essential role of LAT in T cell development","volume":"10","author":"Zhang","year":"1999","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2008.12.008_bib10","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S1074-7613(03)00202-4","article-title":"LAT links the pre-BCR to calcium signaling","volume":"19","author":"Su","year":"2003","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2008.12.008_bib11","doi-asserted-by":"crossref","first-page":"3614","DOI":"10.1002\/eji.200425445","article-title":"The molecular requirements for LAT-mediated differentiation and the role of LAT in limiting pre-B cell expansion","volume":"34","author":"Su","year":"2004","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.imlet.2008.12.008_bib12","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1084\/jem.20021405","article-title":"Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling","volume":"196","author":"Brdicka","year":"2002","journal-title":"J Exp Med"},{"key":"10.1016\/j.imlet.2008.12.008_bib13","doi-asserted-by":"crossref","first-page":"4455","DOI":"10.1128\/MCB.25.11.4455-4465.2005","article-title":"Single and combined deletions of the NTAL\/LAB and LAT adaptors minimally affect B-cell development and function","volume":"25","author":"Wang","year":"2005","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.imlet.2008.12.008_bib14","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.immuni.2004.09.007","article-title":"Grb2 and the non-T cell activation linker NTAL constitute a Ca(2+)-regulating signal circuit in B lymphocytes","volume":"21","author":"Stork","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2008.12.008_bib15","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.immuni.2006.08.025","article-title":"Negative regulation of T cell activation and autoimmunity by the transmembrane adaptor protein LAB","volume":"25","author":"Zhu","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2008.12.008_bib16","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.4049\/jimmunol.178.4.2336","article-title":"The N terminus of the non-T cell activation linker (NTAL) confers inhibitory effects on pre-B cell differentiation","volume":"178","author":"Herzog","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.imlet.2008.12.008_bib17","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/intimm\/dxl118","article-title":"Activation-induced endocytosis of the raft-associated transmembrane adaptor protein LAB\/NTAL in B lymphocytes: evidence for a role in internalization of the B cell receptor","volume":"19","author":"Mutch","year":"2007","journal-title":"Int Immunol"},{"key":"10.1016\/j.imlet.2008.12.008_bib18","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1084\/jem.20031484","article-title":"LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling","volume":"198","author":"Brdickova","year":"2003","journal-title":"J Exp Med"},{"key":"10.1016\/j.imlet.2008.12.008_bib19","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1084\/jem.20030232","article-title":"LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activation","volume":"198","author":"Hur","year":"2003","journal-title":"J Exp Med"},{"key":"10.1016\/j.imlet.2008.12.008_bib20","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1182\/blood-2005-05-1859","article-title":"LIME acts as a transmembrane adapter mediating BCR-dependent B-cell activation","volume":"107","author":"Ahn","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2008.12.008_bib21","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1182\/blood-2005-06-2273","article-title":"Transmembrane adaptor molecules: a new category of lymphoid-cell markers","volume":"107","author":"Tedoldi","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2008.12.008_bib22","first-page":"1783","article-title":"Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL)","volume":"9","author":"Bene","year":"1995","journal-title":"Leukemia"},{"key":"10.1016\/j.imlet.2008.12.008_bib23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1634\/stemcells.19-3-165","article-title":"Transcriptional control of T lymphocyte differentiation","volume":"19","author":"Staal","year":"2001","journal-title":"Stem Cells"},{"key":"10.1016\/j.imlet.2008.12.008_bib24","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal Biochem"},{"key":"10.1016\/j.imlet.2008.12.008_bib25","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/sj.leu.2404047","article-title":"Wilms\u2019 tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: a wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring","volume":"20","author":"Boublikova","year":"2006","journal-title":"Leukemia"},{"key":"10.1016\/j.imlet.2008.12.008_bib26","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1038\/sj.leu.2403136","article-title":"Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using \u2018real-time\u2019 quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR)\u2014a Europe against cancer program","volume":"17","author":"Beillard","year":"2003","journal-title":"Leukemia"},{"key":"10.1016\/j.imlet.2008.12.008_bib27","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1182\/blood-2003-08-2769","article-title":"NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation","volume":"104","author":"Tkaczyk","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2008.12.008_bib28","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/1097-0320(20011101)45:3<194::AID-CYTO1163>3.0.CO;2-C","article-title":"Spectral compensation for flow cytometry: visualization artifacts, limitations, and caveats","volume":"45","author":"Roederer","year":"2001","journal-title":"Cytometry"},{"key":"10.1016\/j.imlet.2008.12.008_bib29","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.exphem.2006.01.018","article-title":"CD27 expression in malignant and normal human B precursors: a confirmed phenomenon. Reply to Nilsson and colleagues","volume":"34","author":"Vaskova","year":"2006","journal-title":"Exp Hematol"},{"key":"10.1016\/j.imlet.2008.12.008_bib30","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.leukres.2004.11.007","article-title":"TEL\/AML1 and immunoreceptor gene rearrangements-which comes first?","volume":"29","author":"Zuna","year":"2005","journal-title":"Leuk Res"},{"key":"10.1016\/j.imlet.2008.12.008_bib31","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1749-6632.2003.tb06045.x","article-title":"Gene expression dynamics during germinal center transit in B cells","volume":"987","author":"Klein","year":"2003","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.imlet.2008.12.008_bib32","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1399-0039.2007.00968.x","article-title":"CD44 and CD27 delineate B-precursor stages with different recombination status and with an uneven distribution in nonmalignant and malignant hematopoiesis","volume":"71","author":"Vaskova","year":"2008","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.imlet.2008.12.008_bib33","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S1074-7613(00)80659-7","article-title":"LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway","volume":"9","author":"Finco","year":"1998","journal-title":"Immunity"}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247809000042?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247809000042?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T18:19:05Z","timestamp":1710008345000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247809000042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S0165247809000042"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2008.12.008","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}