{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:02:50Z","timestamp":1759104170893,"version":"3.44.0"},"reference-count":7,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.imlet.2010.08.004","type":"journal-article","created":{"date-parts":[[2010,8,15]],"date-time":"2010-08-15T04:41:38Z","timestamp":1281847298000},"page":"115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Spatio-temporal dual effects of I\u03baB\u03b6 dictates the caution on visual disturbance resulting from I\u03baB\u03b6 deficiency"],"prefix":"10.1016","volume":"133","author":[{"given":"Mayumi","family":"Ueta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junji","family":"Hamuro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2010.08.004_bib0005","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1038\/nature08922","article-title":"IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors","volume":"464","author":"Okamoto","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.imlet.2010.08.004_bib0010","doi-asserted-by":"crossref","first-page":"3387","DOI":"10.1167\/iovs.08-1691","article-title":"Stat6-independent tissue inflammation occurs selectively on the ocular surface and perioral skin of IkappaBzeta\u2212\/\u2212 mice","volume":"49","author":"Ueta","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.imlet.2010.08.004_bib0015","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/nature02738","article-title":"Regulation of Toll\/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta","volume":"430","author":"Yamamoto","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.imlet.2010.08.004_bib0020","doi-asserted-by":"crossref","first-page":"7444","DOI":"10.1074\/jbc.M412738200","article-title":"Positive and negative regulation of nuclear factor-kappaB-mediated transcription by IkappaB-zeta, an inducible nuclear protein","volume":"280","author":"Motoyama","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.imlet.2010.08.004_bib0025","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1167\/iovs.04-1055","article-title":"Spontaneous ocular surface inflammation and goblet cell disappearance in I kappa B zeta gene-disrupted mice","volume":"46","author":"Ueta","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.imlet.2010.08.004_bib0030","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.brainresbull.2009.10.001","article-title":"Innate immunity of the ocular surface","volume":"81","author":"Ueta","year":"2010","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.imlet.2010.08.004_bib0035","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.ophtha.2006.10.029","article-title":"New grading system for the evaluation of chronic ocular manifestations in patients with Stevens\u2013Johnson syndrome","volume":"114","author":"Sotozono","year":"2007","journal-title":"Ophthalmology"}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247810001987?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247810001987?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T07:30:22Z","timestamp":1759044622000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247810001987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["S0165247810001987"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2010.08.004","relation":{},"ISSN":["0165-2478"],"issn-type":[{"type":"print","value":"0165-2478"}],"subject":[],"published":{"date-parts":[[2010,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spatio-temporal dual effects of I\u03baB\u03b6 dictates the caution on visual disturbance resulting from I\u03baB\u03b6 deficiency","name":"articletitle","label":"Article Title"},{"value":"Immunology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imlet.2010.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}