{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T22:39:41Z","timestamp":1791758381563,"version":"4.3.4"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.imlet.2016.04.012","type":"journal-article","created":{"date-parts":[[2016,4,29]],"date-time":"2016-04-29T16:32:19Z","timestamp":1461947539000},"page":"53-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Association study of inflammatory genes with rheumatic heart disease in North Indian population: A multi-analytical approach"],"prefix":"10.1016","volume":"174","author":[{"given":"Usha","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Snober S.","family":"Mir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveen","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surendra K.","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shantanu","family":"Pande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balraj","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2\u20133","key":"10.1016\/j.imlet.2016.04.012_bib0005","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1365-3083.2007.01974.x","article-title":"Rheumatic fever and rheumatic heart disease: genetics and pathogenesis","volume":"66","author":"Guilherme","year":"2007","journal-title":"Scand. J. Immunol."},{"issue":"9","key":"10.1016\/j.imlet.2016.04.012_bib0010","doi-asserted-by":"crossref","first-page":"e25326","DOI":"10.1371\/journal.pone.0025326","article-title":"Genetic susceptibility to acute rheumatic fever: a systematic review and meta-analysis of twin studies","volume":"6","author":"Engel","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0015","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s10875-009-9332-6","article-title":"Rheumatic fever and rheumatic heart disease: cellular mechanisms leading autoimmune reactivity and disease","volume":"30","author":"Guilherme","year":"2010","journal-title":"J. Clin. Immunol."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0020","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000157039","article-title":"Biologic activities of interleukin-1 relevant to rheumatic diseases","volume":"6","author":"Miller","year":"1987","journal-title":"Pathol. Immunopathol. Res."},{"issue":"5","key":"10.1016\/j.imlet.2016.04.012_bib0025","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/S0002-9440(10)63415-3","article-title":"Rheumatic heart disease: proinflammatory cytokines play a role in the progression and maintenance of valvular lesions","volume":"165","author":"Guilherme","year":"2004","journal-title":"Am. J. Pathol."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0030","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1046\/j.1365-2249.1999.00853.x","article-title":"Superantigen-induced T cell responses in acute rheumatic fever and chronic rheumatic heart disease patients","volume":"116","author":"Bhatnagar","year":"1999","journal-title":"Clin. Exp. Immunol."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0035","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nrcardio.2012.157","article-title":"Screening for rheumatic heart disease: current approaches and controversies","volume":"10","author":"Roberts","year":"2013","journal-title":"Nat. Rev. Cardiol."},{"issue":"6","key":"10.1016\/j.imlet.2016.04.012_bib0040","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/j.1399-0039.2009.01347.x","article-title":"Cytotoxic T lymphocyte-associated antigen-4 polymorphism in patients with rheumatic heart disease","volume":"74","author":"Duzgun","year":"2009","journal-title":"Tissue Antigens"},{"issue":"5","key":"10.1016\/j.imlet.2016.04.012_bib0045","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s00246-006-0002-7","article-title":"Gene polymorphisms of TNF-alpha(-308), IL-10(-1082), IL-6(-174), and IL-1Ra(VNTR) related to susceptibility and severity of rheumatic heart disease","volume":"28","author":"Settin","year":"2007","journal-title":"Pediatr. Cardiol."},{"issue":"2","key":"10.1016\/j.imlet.2016.04.012_bib0050","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.cyto.2012.10.020","article-title":"A study on the association of TNF-alpha(-308), IL-6(-174), IL-10(-1082) and IL-1Ra(VNTR) gene polymorphisms with rheumatic heart disease in Pakistani patients","volume":"61","author":"Rehman","year":"2013","journal-title":"Cytokine"},{"issue":"4","key":"10.1016\/j.imlet.2016.04.012_bib0055","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/S0008-6363(01)00534-X","article-title":"Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein","volume":"53","author":"Vickers","year":"2002","journal-title":"Cardiovasc. Res."},{"issue":"24","key":"10.1016\/j.imlet.2016.04.012_bib0060","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1053\/euhj.2001.2678","article-title":"The interleukin-6-174 G\/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men","volume":"22","author":"Humphries","year":"2001","journal-title":"Eur. Heart J."},{"issue":"5","key":"10.1016\/j.imlet.2016.04.012_bib0065","first-page":"944","article-title":"Polymorphisms in the IL6 gene in Asian Indian families with premature coronary artery disease\u2014the Indian Atherosclerosis Research Study","volume":"99","author":"Maitra","year":"2008","journal-title":"Thromb. Haemost."},{"issue":"4","key":"10.1016\/j.imlet.2016.04.012_bib0070","first-page":"863","article-title":"The interleukin-6-174 G\/C promoter polymorphism and arterial stiffness; the Rotterdam Study","volume":"4","author":"Sie","year":"2008","journal-title":"Vasc. Health Risk Manage."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0075","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1590\/S0100-879X2006005000190","article-title":"Association between the \u2212174 G\/C promoter polymorphism of the interleukin-6 gene and cardiovascular disease risk factors in Brazilian older women","volume":"41","author":"Tonet","year":"2008","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"7","key":"10.1016\/j.imlet.2016.04.012_bib0080","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1172\/JCI2629","article-title":"The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis","volume":"102","author":"Fishman","year":"1998","journal-title":"J. Clin. Investig."},{"issue":"14","key":"10.1016\/j.imlet.2016.04.012_bib0085","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1161\/01.CIR.97.14.1382","article-title":"Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats","volume":"97","author":"Bozkurt","year":"1998","journal-title":"Circulation"},{"issue":"23","key":"10.1016\/j.imlet.2016.04.012_bib0090","doi-asserted-by":"crossref","first-page":"12746","DOI":"10.1073\/pnas.97.23.12746","article-title":"Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy","volume":"97","author":"Li","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.imlet.2016.04.012_bib0095","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/01.psy.0000130903.78444.7d","article-title":"Elevated plasma C-reactive protein in chronically distressed subjects who carry the A allele of the TNF-alpha \u2212308 G\/A polymorphism","volume":"66","author":"Jeanmonod","year":"2004","journal-title":"Psychosom. Med."},{"issue":"4","key":"10.1016\/j.imlet.2016.04.012_bib0100","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1515\/CCLM.2003.077","article-title":"The \u2212308 G\/A tumor necrosis factor-alpha gene dimorphism: a risk factor for unstable angina","volume":"41","author":"Bernard","year":"2003","journal-title":"Clin. Chem. Lab. Med."},{"issue":"5","key":"10.1016\/j.imlet.2016.04.012_bib0105","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1165\/ajrcmb.21.5.3755","article-title":"Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice","volume":"21","author":"Stampfli","year":"1999","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"11","key":"10.1016\/j.imlet.2016.04.012_bib0110","doi-asserted-by":"crossref","first-page":"3941","DOI":"10.1182\/blood.V94.11.3941","article-title":"Recipient tumor necrosis factor-alpha and interleukin-10 gene polymorphisms associate with early mortality and acute graft-versus-host disease severity in HLA-matched sibling bone marrow transplants","volume":"94","author":"Cavet","year":"1999","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0115","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s11033-011-0712-7","article-title":"Associations between interleukin-10 polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis","volume":"39","author":"Lee","year":"2012","journal-title":"Mol. Biol. Rep."},{"issue":"2","key":"10.1016\/j.imlet.2016.04.012_bib0120","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1744-313X.2011.01072.x","article-title":"Association between the Interleukin 10-1082G>A polymorphism and coronary heart disease risk in a Caucasian population: a meta-analysis","volume":"39","author":"Wang","year":"2012","journal-title":"Int. J. Immunogenet."},{"issue":"20","key":"10.1016\/j.imlet.2016.04.012_bib0125","doi-asserted-by":"crossref","first-page":"11008","DOI":"10.1073\/pnas.93.20.11008","article-title":"Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice","volume":"93","author":"Hirsch","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.imlet.2016.04.012_bib0130","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/BF00217368","article-title":"Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat","volume":"91","author":"Tarlow","year":"1993","journal-title":"Hum. Genet."},{"issue":"4","key":"10.1016\/j.imlet.2016.04.012_bib0135","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1046\/j.1365-2370.2002.00319.x","article-title":"The interleukin-1 receptor antagonist gene: a single-copy variant of the intron 2 variable number tandem repeat (VNTR) polymorphism","volume":"29","author":"Vamvakopoulos","year":"2002","journal-title":"Eur. J. Immunogenet."},{"issue":"18","key":"10.1016\/j.imlet.2016.04.012_bib0140","doi-asserted-by":"crossref","first-page":"5095","DOI":"10.1093\/nar\/19.18.5095","article-title":"Length variation within intron 2 of the human IL-1 receptor antagonist protein gene (IL1RN)","volume":"19","author":"Steinkasserer","year":"1991","journal-title":"Nucleic Acids Res."},{"issue":"2","key":"10.1016\/j.imlet.2016.04.012_bib0145","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1086\/338261","article-title":"Influence of interleukin-1 receptor antagonist gene polymorphism on disease","volume":"34","author":"Witkin","year":"2002","journal-title":"Clin. Infect. Dis."},{"issue":"11","key":"10.1016\/j.imlet.2016.04.012_bib0150","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1161\/01.ATV.15.11.1951","article-title":"In vivo effect of TGF-beta 1. Enhanced intimal thickening by administration of TGF-beta 1 in rabbit arteries injured with a balloon catheter","volume":"15","author":"Kanzaki","year":"1995","journal-title":"Arteriosclerosis Thromb. Vasc. Biol."},{"issue":"12","key":"10.1016\/j.imlet.2016.04.012_bib0155","doi-asserted-by":"crossref","first-page":"6983","DOI":"10.1073\/pnas.95.12.6983","article-title":"Overexpression of transforming growth factor beta1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia","volume":"95","author":"Schulick","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5483\/BMBRep.2005.38.1.001","article-title":"Transforming growth factor-beta: biology and clinical relevance","volume":"38","author":"Kim","year":"2005","journal-title":"J. Biochem. Mol. Biol."},{"issue":"7","key":"10.1016\/j.imlet.2016.04.012_bib0165","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1096\/fj.03-1273rev","article-title":"TGF-beta signaling and the fibrotic response","volume":"18","author":"Leask","year":"2004","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0170","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/hmg\/8.1.93","article-title":"Genetic control of the circulating concentration of transforming growth factor type beta1","volume":"8","author":"Grainger","year":"1999","journal-title":"Hum. Mol. Genet."},{"issue":"2","key":"10.1016\/j.imlet.2016.04.012_bib0175","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1164\/rccm.200307-973OC","article-title":"Transforming growth factor-beta1 promoter polymorphism C-509T is associated with asthma","volume":"169","author":"Silverman","year":"2004","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"24","key":"10.1016\/j.imlet.2016.04.012_bib0180","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1161\/01.CIR.101.24.2783","article-title":"Association of a T29-->C polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to myocardial infarction in Japanese","volume":"101","author":"Yokota","year":"2000","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.imlet.2016.04.012_bib0185","first-page":"3479","article-title":"Transforming growth factor-beta 1 hyperexpression in African\u2013American hypertensives: a novel mediator of hypertension and\/or target organ damage","volume":"97","author":"Suthanthiran","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.imlet.2016.04.012_bib0190","first-page":"2610","article-title":"A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer","volume":"63","author":"Dunning","year":"2003","journal-title":"Cancer Res."},{"key":"10.1016\/j.imlet.2016.04.012_bib0195","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.0105-2896.2005.00249.x","article-title":"CTLA4 gene polymorphism and autoimmunity","volume":"204","author":"Gough","year":"2005","journal-title":"Immunol. Rev."},{"issue":"10","key":"10.1016\/j.imlet.2016.04.012_bib0200","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/S0198-8859(03)00171-X","article-title":"CTLA4 polymorphism in Spanish patients with systemic lupus erythematosus","volume":"64","author":"Aguilar","year":"2003","journal-title":"Hum. Immunol."},{"issue":"2\u20133","key":"10.1016\/j.imlet.2016.04.012_bib0205","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.clim.2005.09.017","article-title":"Genetic analysis and functional evaluation of the C\/T(-318) and A\/G(-1661) polymorphisms of the CTLA-4 gene in patients affected with Graves' disease","volume":"118","author":"Chistiakov","year":"2006","journal-title":"Clin. Immunol."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0210","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1365-2249.1997.t01-1-512-ce1410.x","article-title":"CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. The Belgian Diabetes Registry","volume":"110","author":"Van der Auwera","year":"1997","journal-title":"Clin. Exp. Immunol."},{"issue":"2","key":"10.1016\/j.imlet.2016.04.012_bib0215","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1093\/rheumatology\/41.2.180","article-title":"An association between the CTLA4 exon 1 polymorphism and early rheumatoid arthritis with autoimmune endocrinopathies","volume":"41","author":"Vaidya","year":"2002","journal-title":"Rheumatology"},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0220","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/sj.gene.6363816","article-title":"CDS1 and promoter single nucleotide polymorphisms of the CTLA-4 gene in human myasthenia gravis","volume":"3","author":"Wang","year":"2002","journal-title":"Genes Immun."},{"issue":"3","key":"10.1016\/j.imlet.2016.04.012_bib0225","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1469-8749.1992.tb15000.x","article-title":"Visual hallucinations after acute visual loss in a young child","volume":"34","author":"White","year":"1992","journal-title":"Dev. Med. Child Neurol."},{"issue":"2","key":"10.1016\/j.imlet.2016.04.012_bib0230","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0198-8859(02)00782-6","article-title":"CTLA-4 +49 A\/G dimorphism in Italian patients with celiac disease","volume":"64","author":"Mora","year":"2003","journal-title":"Hum. Immunol."},{"issue":"5402","key":"10.1016\/j.imlet.2016.04.012_bib0235","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1136\/bmj.2.5402.177","article-title":"Human experimentation. Code of ethics of the World Medical Association. Declaration of Helsinki","volume":"2","author":"Rickham","year":"1964","journal-title":"Br. Med. J."},{"key":"10.1016\/j.imlet.2016.04.012_bib0240","volume":"vol. 10","author":"Douglas","year":"2015"},{"key":"10.1016\/j.imlet.2016.04.012_bib0245","first-page":"1446","volume":"vol. 9","author":"Douglas","year":"2015"},{"issue":"17","key":"10.1016\/j.imlet.2016.04.012_bib0250","doi-asserted-by":"crossref","first-page":"E88","DOI":"10.1093\/nar\/29.17.e88","article-title":"An efficient procedure for genotyping single nucleotide polymorphisms","volume":"29","author":"Ye","year":"2001","journal-title":"Nucleic Acids Res."},{"issue":"2","key":"10.1016\/j.imlet.2016.04.012_bib0255","doi-asserted-by":"crossref","first-page":"177","DOI":"10.2143\/AC.65.2.2047051","article-title":"Transforming growth factor-beta1 gene C-509T and T869C polymorphisms as possible risk factors in rheumatic heart disease in Egypt","volume":"65","author":"Kamal","year":"2010","journal-title":"Acta Cardiol."},{"issue":"6","key":"10.1016\/j.imlet.2016.04.012_bib0260","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1089\/dna.2008.0842","article-title":"Transforming growth factor-B1 and matrix metalloproteinase-7 promoter variants induce risk for Helicobacter pylori-associated gastric precancerous lesions","volume":"28","author":"Achyut","year":"2009","journal-title":"DNA Cell Biol."},{"issue":"3","key":"10.1016\/j.imlet.2016.04.012_bib0265","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1093\/bioinformatics\/btf869","article-title":"Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions","volume":"19","author":"Hahn","year":"2003","journal-title":"Bioinformatics"},{"issue":"7","key":"10.1016\/j.imlet.2016.04.012_bib0270","doi-asserted-by":"crossref","first-page":"e40162","DOI":"10.1371\/journal.pone.0040162","article-title":"Significant role of estrogen and progesterone receptor sequence variants in gallbladder cancer predisposition: a multi-analytical strategy","volume":"7","author":"Srivastava","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0275","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.ahj.2004.03.032","article-title":"Association between transforming growth factor-beta1 gene C-509T and T869C polymorphisms and rheumatic heart disease","volume":"148","author":"Chou","year":"2004","journal-title":"Am. Heart J."},{"issue":"10","key":"10.1016\/j.imlet.2016.04.012_bib0280","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1359\/jbmr.1998.13.10.1569","article-title":"Association of a polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to osteoporosis in postmenopausal Japanese women","volume":"13","author":"Yamada","year":"1998","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.imlet.2016.04.012_bib0285","first-page":"175381","article-title":"Transforming growth factor-beta1 as a common target molecule for development of cardiovascular diseases renal insufficiency and metabolic syndrome","volume":"2011","author":"Aihara","year":"2010","journal-title":"Cardiol. Res. Pract."},{"key":"10.1016\/j.imlet.2016.04.012_bib0290","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1161\/01.HYP.33.1.271","article-title":"TGF-beta1 DNA polymorphisms protein levels, and blood pressure","volume":"33","author":"Li","year":"1999","journal-title":"Hypertension"},{"issue":"8","key":"10.1016\/j.imlet.2016.04.012_bib0295","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.molimm.2006.10.001","article-title":"Association of polymorphisms within the promoter region of the tumor necrosis factor-alpha with clinical outcomes of rheumatic fever","volume":"44","author":"Ramasawmy","year":"2007","journal-title":"Mol. Immunol."},{"issue":"2","key":"10.1016\/j.imlet.2016.04.012_bib0300","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jaut.2005.05.005","article-title":"TNF-alpha G-308A polymorphism is associated with rheumatic fever and correlates with increased TNF-alpha production","volume":"25","author":"Sallakci","year":"2005","journal-title":"J. Autoimmun."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0305","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0896-8411(03)00079-9","article-title":"Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with rheumatic heart disease","volume":"21","author":"Hernandez-Pacheco","year":"2003","journal-title":"J. Autoimmun."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0310","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.1365-2249.2007.03394.x","article-title":"Association of \u2212318C\/T and +49 A\/G cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms with a clinical subset of Italian patients with systemic sclerosis","volume":"149","author":"Balbi","year":"2007","journal-title":"Clin. Exp. Immunol."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0315","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1469-1809.2010.00604.x","article-title":"Model-based multifactor dimensionality reduction for detecting epistasis in case-control data in the presence of noise","volume":"75","author":"Cattaert","year":"2011","journal-title":"Ann. Hum. Genet."},{"issue":"1","key":"10.1016\/j.imlet.2016.04.012_bib0320","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1086\/321276","article-title":"Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer","volume":"69","author":"Ritchie","year":"2001","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.imlet.2016.04.012_bib0325","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1471-2156-5-32","article-title":"Screening large-scale association study data: exploiting interactions using random forests","volume":"5","author":"Lunetta","year":"2004","journal-title":"BMC Genet."}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247816300633?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247816300633?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,19]],"date-time":"2020-09-19T03:53:39Z","timestamp":1600487619000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247816300633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":65,"alternative-id":["S0165247816300633"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2016.04.012","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association study of inflammatory genes with rheumatic heart disease in North Indian population: A multi-analytical approach","name":"articletitle","label":"Article Title"},{"value":"Immunology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imlet.2016.04.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Published by Elsevier B.V. on behalf of European Federation of Immunological Societies.","name":"copyright","label":"Copyright"}]}}