{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:40:53Z","timestamp":1784133653100,"version":"3.55.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.imlet.2018.09.002","type":"journal-article","created":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T14:26:04Z","timestamp":1536157564000},"page":"1-5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"special_numbering":"C","title":["Myokines, physical activity, insulin resistance and autoimmune diseases"],"prefix":"10.1016","volume":"203","author":[{"given":"Buenaventura Brito","family":"D\u00edaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delia Almeida","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadoua","family":"Gannar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Cristo Rodr\u00edguez","family":"P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Cabrera","family":"de Le\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2018.09.002_bib0005","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1254\/jphs.14R02CP","article-title":"Skeletal muscle is an endocrine organ","volume":"125","author":"Lizuka","year":"2014","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.imlet.2018.09.002_bib0010","doi-asserted-by":"crossref","first-page":"S384","DOI":"10.1097\/CCM.0b013e3181b6f8a5","article-title":"Muscle in defense","volume":"37","author":"Lightfoot","year":"2009","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.imlet.2018.09.002_bib0015","doi-asserted-by":"crossref","first-page":"E453","DOI":"10.1152\/ajpendo.00553.2012","article-title":"Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications","volume":"304","author":"Pillon","year":"2013","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.imlet.2018.09.002_bib0020","doi-asserted-by":"crossref","DOI":"10.1155\/2010\/520258","article-title":"The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases","volume":"2010","author":"Brandt","year":"2010","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0025","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3109\/13813455.2010.535835","article-title":"Secreted proteins from adipose tissue and skeletal muscle-adipokines, myokines and adipose\/muscle cross-talk","volume":"117","author":"Trayhurn","year":"2011","journal-title":"Arch. Physiol. Biochem."},{"key":"10.1016\/j.imlet.2018.09.002_bib0030","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1023\/A:1026070911202","article-title":"Searching for the exercise factor: is IL-6 a candidate?","volume":"24","author":"Pedersen","year":"2003","journal-title":"J. Muscle Res. Cell. Motil."},{"key":"10.1016\/j.imlet.2018.09.002_bib0035","first-page":"265","article-title":"Physiological roles of muscle-derived interleukin-6 in response to exercise","volume":"10","author":"Pedersen","year":"2007","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.imlet.2018.09.002_bib0040","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1079\/PNS2004338","article-title":"The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor?","volume":"63","author":"Pedersen","year":"2004","journal-title":"Proc. Nutr. Soc."},{"key":"10.1016\/j.imlet.2018.09.002_bib0045","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.bbi.2005.04.008","article-title":"Muscle-derived interleukin-6-a possible link between skeletal muscle, adipose tissue, liver, and brain","volume":"19","author":"Pedersen","year":"2005","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.imlet.2018.09.002_bib0050","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1113\/expphysiol.2012.068189","article-title":"The regulation of interleukin-6 implicates skeletal muscle as an integrative stress sensor and endocrine organ","volume":"98","author":"Welc","year":"2013","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0055","doi-asserted-by":"crossref","first-page":"E191","DOI":"10.1152\/ajpendo.90506.2008","article-title":"Oversecretion of interleukin-15 from skeletal muscle reduces adiposity","volume":"296","author":"Quinn","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.imlet.2018.09.002_bib0060","doi-asserted-by":"crossref","first-page":"200","DOI":"10.4161\/adip.20877","article-title":"Regulation of tissue cross-talk by skeletal muscle-derived myonectin and other myokines","volume":"1","author":"Seldin","year":"2012","journal-title":"Adipocyte"},{"key":"10.1016\/j.imlet.2018.09.002_bib0065","doi-asserted-by":"crossref","first-page":"11968","DOI":"10.1074\/jbc.M111.336834","article-title":"Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis","volume":"287","author":"Seldin","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imlet.2018.09.002_bib0070","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nrendo.2012.49","article-title":"Muscles, exercise and obesity: skeletal muscle as a secretory organ","volume":"8","author":"Pedersen","year":"2012","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0075","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nature10777","article-title":"A PGC1-\u03b1-dependent myokine that drives brown-fat-like development of white fat and thermogenesis","volume":"481","author":"Bostr\u00f6m","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.imlet.2018.09.002_bib0080","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1007\/s00125-014-3224-x","article-title":"Myokines in insulin resistance and type 2 diabetes","volume":"57","author":"Eckardt","year":"2014","journal-title":"Diabetologia"},{"key":"10.1016\/j.imlet.2018.09.002_bib0085","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1017\/S1751731110000601","article-title":"Ontogenesis of muscle and adipose tissues and their interactions in ruminants and other species","volume":"4","author":"Bonnet","year":"2010","journal-title":"Animal"},{"key":"10.1016\/j.imlet.2018.09.002_bib0090","doi-asserted-by":"crossref","first-page":"26","DOI":"10.5493\/wjem.v3.i3.26","article-title":"Interplay of adipokines and myokines in cancer pathophysiology: emerging therapeutic implications","volume":"3","author":"Dalamaga","year":"2013","journal-title":"World J. Exp. Med."},{"key":"10.1016\/j.imlet.2018.09.002_bib0095","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/320724","article-title":"Adipo-myokines: two sides of the same coin--mediators of inflammation and mediators of exercise","volume":"2013","author":"Raschke","year":"2013","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.imlet.2018.09.002_bib0100","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1189\/jlb.0505247","article-title":"Physical activity and modulation of systemic low-level inflammation","volume":"78","author":"Bruunsgaard","year":"2005","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0105","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/dom.12156","article-title":"The effect of physical activity on mediators of inflammation","volume":"15","author":"Nimmo","year":"2013","journal-title":"Diabetes Obes. Metab."},{"issue":"2007","key":"10.1016\/j.imlet.2018.09.002_bib0110","first-page":"1093","article-title":"Role of myokines in exercise and metabolism","volume":"103","author":"Pedersen","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0115","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.tips.2007.02.002","article-title":"Beneficial health effects of exercise\u2014the role of IL-6 as a myokine","volume":"28","author":"Pedersen","year":"2007","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.imlet.2018.09.002_bib0120","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1152\/physrev.90100.2007","article-title":"Muscle as an endocrine organ: focus on muscle-derived interleukin-6","volume":"88","author":"Pedersen","year":"2008","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.imlet.2018.09.002_bib0125","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.coph.2008.02.005","article-title":"Skeletal muscle as an immunogenic organ","volume":"8","author":"Nielsen","year":"2008","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0130","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1097\/BOR.0000000000000337","article-title":"The role of myokines in muscle health and disease","volume":"28","author":"Lightfoot","year":"2016","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0135","doi-asserted-by":"crossref","first-page":"4326","DOI":"10.2174\/138161212802481192","article-title":"Effects of physical exercise on inflammatory markers of atherosclerosis","volume":"18","author":"Pinto","year":"2012","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.imlet.2018.09.002_bib0140","doi-asserted-by":"crossref","first-page":"R667","DOI":"10.1152\/ajpregu.00336.2011","article-title":"Resistance exercise increases NF-\u03baB activity in human skeletal muscle","volume":"302","author":"Vella","year":"2012","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0145","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.tem.2008.12.002","article-title":"ROS and myokines promote muscle adaptation to exercise","volume":"20","author":"Scheele","year":"2009","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.imlet.2018.09.002_bib0150","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s40279-013-0017-1","article-title":"Potential mechanisms for a role of metabolic stress in hypertrophic adaptations to resistance training","volume":"43","author":"Schoenfeld","year":"2013","journal-title":"Sports Med."},{"key":"10.1016\/j.imlet.2018.09.002_bib0155","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1253\/circj.CJ-08-0961","article-title":"Adipokines, myokines and cardiovascular disease","volume":"73","author":"Walsh","year":"2009","journal-title":"Circ. J."},{"key":"10.1016\/j.imlet.2018.09.002_bib0160","first-page":"448","article-title":"The effects of different exercise intensity on myokine and angiogenesis factors","volume":"52","author":"Yeo","year":"2012","journal-title":"J. Sports Med. Phys. Fitness"},{"issue":"2008","key":"10.1016\/j.imlet.2018.09.002_bib0165","first-page":"853","article-title":"Muscle-derived ROS and thiol regulation in muscle fatigue","volume":"104","author":"Ferreira","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0170","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/00005768-200103000-00008","article-title":"Redox regulation of skeletal muscle glucose transport","volume":"33","author":"Balon","year":"2001","journal-title":"Med. Sci. Sports Exerc."},{"key":"10.1016\/j.imlet.2018.09.002_bib0175","first-page":"365","article-title":"Myokines-muscle tissue hormones","volume":"61","author":"Str\u00e1nsk\u00e1","year":"2015","journal-title":"Vnitr. Lek."},{"key":"10.1016\/j.imlet.2018.09.002_bib0180","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1042\/BST0351295","article-title":"IL-6 signalling in exercise and disease","volume":"35","author":"Pedersen","year":"2007","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.imlet.2018.09.002_bib0185","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1111\/j.1469-7793.1998.949bp.x","article-title":"Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running","volume":"508","author":"Ostrowski","year":"1998","journal-title":"J. Physiol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0190","doi-asserted-by":"crossref","first-page":"E433","DOI":"10.1152\/ajpendo.00074.2003","article-title":"IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans","volume":"285","author":"Steensberg","year":"2003","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.imlet.2018.09.002_bib0195","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1469-7793.2000.00237.x","article-title":"Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6","volume":"529","author":"Steensberg","year":"2000","journal-title":"J. Physiol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0200","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.1469-7793.2001.00633.x","article-title":"Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content","volume":"537","author":"Steensberg","year":"2001","journal-title":"J. Physiol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0205","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1096\/fj.03-1259fje","article-title":"Skeletal myocytes are a source of interleukin-6 mRNA expression and protein release during contraction: evidence of fiber type specificity","volume":"18","author":"Hiscock","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.imlet.2018.09.002_bib0210","doi-asserted-by":"crossref","first-page":"10771","DOI":"10.1074\/jbc.M111.310581","article-title":"Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase\/activator protein-1","volume":"287","author":"Whitham","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.imlet.2018.09.002_bib0215","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.2337\/diabetes.53.7.1643","article-title":"Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction","volume":"53","author":"Febbraio","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.imlet.2018.09.002_bib0220","doi-asserted-by":"crossref","DOI":"10.1155\/2008\/109502","article-title":"Exercise as a mean to control low-grade systemic inflammation","volume":"2008","author":"Mathur","year":"2008","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.imlet.2018.09.002_bib0225","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.bbi.2011.02.010","article-title":"Exercise-induced myokines and their role in chronic diseases","volume":"25","author":"Pedersen","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.imlet.2018.09.002_bib0230","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1042\/bse0420105","article-title":"The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control","volume":"42","author":"Pedersen","year":"2006","journal-title":"Essays Biochem."},{"key":"10.1016\/j.imlet.2018.09.002_bib0235","first-page":"11","article-title":"Skeletal muscle: an endocrine organ","volume":"10","author":"Pratesi","year":"2013","journal-title":"Clin. Cases Miner. Bone Metab."},{"key":"10.1016\/j.imlet.2018.09.002_bib0240","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1242\/jeb.048074","article-title":"Muscles and their myokines","volume":"214","author":"Pedersen","year":"2011","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0245","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000281883","article-title":"PGC-1\u03b1 and myokines in the aging muscle - a mini-review","volume":"57","author":"Arnold","year":"2011","journal-title":"Gerontology"},{"key":"10.1016\/j.imlet.2018.09.002_bib0250","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1111\/acel.12126","article-title":"The influence of skeletal muscle on systemic aging and lifespan","volume":"12","author":"Demontis","year":"2013","journal-title":"Aging Cell"},{"key":"10.1016\/j.imlet.2018.09.002_bib0255","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1503\/cmaj.150684","article-title":"Prescribing exercise interventions for patients with chronic conditions","volume":"188","author":"Hoffmann","year":"2016","journal-title":"CMAJ"},{"issue":"2005","key":"10.1016\/j.imlet.2018.09.002_bib0260","first-page":"1154","article-title":"The anti-inflammatory effect of exercise","volume":"98","author":"Petersen","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0265","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/icb.2014.16","article-title":"From cytokine to myokine: the emerging role of interleukin-6 in metabolic regulation","volume":"92","author":"Pal","year":"2014","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0270","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/icb.2015.101","article-title":"Exercise and type 2 diabetes: focus on metabolism and inflammation","volume":"94","author":"Karstoft","year":"2016","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0275","doi-asserted-by":"crossref","first-page":"355","DOI":"10.2337\/db11-1790","article-title":"Altered response of skeletal muscle to IL-6 in type 2 diabetic patients","volume":"62","author":"Jiang","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.imlet.2018.09.002_bib0280","doi-asserted-by":"crossref","first-page":"E657","DOI":"10.1152\/ajpendo.00186.2009","article-title":"Functional significance of skeletal muscle adiponectin production, changes in animal models of obesity and diabetes, and regulation by rosiglitazone treatment","volume":"297","author":"Liu","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.imlet.2018.09.002_bib0285","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1007\/s00125-015-3584-x","article-title":"Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery","volume":"58","author":"Hansen","year":"2015","journal-title":"Diabetologia"},{"key":"10.1016\/j.imlet.2018.09.002_bib0290","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1463-1326.2012.01641.x","article-title":"Bimodal impact of skeletal muscle on pancreatic \u03b2-cell function in health and disease","volume":"14","author":"Plomgaard","year":"2012","journal-title":"Diabetes Obes. Metab."},{"key":"10.1016\/j.imlet.2018.09.002_bib0295","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.mehy.2011.11.021","article-title":"Can multiple intramuscular injections of mesenchymal stromal cells overcome insulin resistance offering an alternative mode of cell therapy for type 2 diabetes?","volume":"78","author":"Gopurappilly","year":"2012","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.imlet.2018.09.002_bib0300","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/obr.12166","article-title":"Potential role of skeletal muscle glucose metabolism on the regulation of insulin secretion","volume":"15","author":"Mizgier","year":"2014","journal-title":"Obes. Rev."},{"key":"10.1016\/j.imlet.2018.09.002_bib0305","doi-asserted-by":"crossref","first-page":"5315","DOI":"10.1021\/pr200573b","article-title":"Proteomic analysis of tumor necrosis factor-alpha (TNF-\u03b1)-induced L6 myotube secretome reveals novel TNF-\u03b1-dependent myokines in diabetic skeletal muscle","volume":"10","author":"Yoon","year":"2011","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.imlet.2018.09.002_bib0310","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/nrrheum.2014.193","article-title":"Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation","volume":"11","author":"Benatti","year":"2015","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.imlet.2018.09.002_bib0315","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.autrev.2017.11.010","article-title":"Physical activity and autoimmune diseases: get moving and manage the disease","volume":"17","author":"Sharif","year":"2018","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.imlet.2018.09.002_bib0320","first-page":"143","article-title":"The impact of physical activity and nutrition on inflammatory bowel disease: the potential role of cross talk between adipose tissue and skeletal muscle","volume":"64","author":"Bilski","year":"2013","journal-title":"J. Physiol. Pharmacol."}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016524781830302X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016524781830302X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T07:34:33Z","timestamp":1759044873000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016524781830302X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":64,"alternative-id":["S016524781830302X"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2018.09.002","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Myokines, physical activity, insulin resistance and autoimmune diseases","name":"articletitle","label":"Article Title"},{"value":"Immunology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imlet.2018.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 European Federation of Immunological Societies. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}