{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:22:08Z","timestamp":1786990928345,"version":"build-2736575974"},"reference-count":244,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T00:00:00Z","timestamp":1686528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["456067883"],"award-info":[{"award-number":["456067883"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["09150162010166"],"award-info":[{"award-number":["09150162010166"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005039","name":"Leids Universitair Medisch Centrum","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005039","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.imlet.2023.06.005","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T11:17:23Z","timestamp":1686568643000},"page":"44-57","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Targeting plasma cells in systemic autoimmune rheumatic diseases \u2013 Promises and pitfalls"],"prefix":"10.1016","volume":"260","author":[{"given":"Tobit D.","family":"Steinmetz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwenny M.","family":"Verstappen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolien","family":"Suurmond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frans G.M.","family":"Kroese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2023.06.005_bib0001","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.immuni.2010.06.015","article-title":"Development and migration of plasma cells in the mouse lymph node","volume":"33","author":"Fooksman","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0002","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/imr.12992","article-title":"Biochemical coordination of plasma cell genesis","volume":"303","author":"Gaudette","year":"2021","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0003","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/imr.13010","article-title":"Cell fate dynamics and genomic programming of plasma cell precursors","volume":"303","author":"Manakkat Vijay","year":"2021","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0004","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/imr.12988","article-title":"The gene regulatory network controlling plasma cell function","volume":"303","author":"Trezise","year":"2021","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0005","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/nri3795","article-title":"The generation of antibody-secreting plasma cells","volume":"15","author":"Nutt","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0006","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1038\/s41467-017-01901-w","article-title":"Plasma cell survival in the absence of B cell memory","volume":"8","author":"Hammarlund","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0007","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1084\/jem.20161590","article-title":"Antibody-secreting plasma cells persist for decades in human intestine","volume":"214","author":"Landsverk","year":"2017","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0008","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/40540","article-title":"Lifetime of plasma cells in the bone marrow","volume":"388","author":"Manz","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.imlet.2023.06.005_bib0009","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1196\/annals.1313.014","article-title":"Long-lived plasma cells and their contribution to autoimmunity","volume":"1050","author":"Hoyer","year":"2005","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.imlet.2023.06.005_bib0010","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/nrrheum.2011.1","article-title":"Long-lived autoreactive plasma cells drive persistent autoimmune inflammation","volume":"7","author":"Hiepe","year":"2011","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0011","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.coi.2019.09.005","article-title":"Pathogenic memory plasma cells in autoimmunity","volume":"61","author":"Chang","year":"2019","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0012","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1177\/0961203306076223","article-title":"Cardiovascular autonomic dysfunction in systemic lupus, rheumatoid arthritis, primary Sj\u00f6gren syndrome and other autoimmune diseases","volume":"16","author":"Stojanovich","year":"2007","journal-title":"Lupus"},{"key":"10.1016\/j.imlet.2023.06.005_bib0013","series-title":"Handb. Clin. Neurol","first-page":"463","article-title":"Chapter 30 - connective tissue disorders: systemic lupus erythematosus, Sj\u00f6gren's syndrome, and scleroderma","author":"Streifler","year":"2014"},{"key":"10.1016\/j.imlet.2023.06.005_bib0014","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1055\/s-0038-1639473","article-title":"Musculoskeletal manifestations of non-RA connective tissue diseases: scleroderma, systemic lupus erythematosus, still's disease, dermatomyositis\/polymyositis, Sj\u00f6gren's syndrome, and mixed connective tissue disease","volume":"22","author":"Jacques","year":"2018","journal-title":"Semin. Musculoskelet. Radiol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0015","doi-asserted-by":"crossref","first-page":"h6819","DOI":"10.1136\/bmj.h6819","article-title":"Management of interstitial lung disease associated with connective tissue disease","volume":"352","author":"Mathai","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.imlet.2023.06.005_bib0016","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1741-7015-11-95","article-title":"Renal involvement in autoimmune connective tissue diseases","volume":"11","author":"Kronbichler","year":"2013","journal-title":"BMC Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0017","first-page":"344","article-title":"Skin involvement in systemic autoimmune diseases","volume":"10","author":"Rashtak","year":"2008","journal-title":"Dermatol. Immun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0018","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/art.41927","article-title":"Defective early B cell tolerance checkpoints in patients with systemic sclerosis allow the production of self antigen\u2013specific clones","volume":"74","author":"Glauzy","year":"2022","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0019","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1038\/s41590-022-01253-8","article-title":"Targeting TFH cells in human diseases and vaccination: rationale and practice","volume":"23","author":"Yu","year":"2022","journal-title":"Nat. Immunol."},{"issue":"Suppl 126","key":"10.1016\/j.imlet.2023.06.005_bib0020","first-page":"271","article-title":"When B cells break bad: development of pathogenic B cells in Sj\u00f6gren's syndrome","volume":"38","author":"Reed","year":"2020","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0021","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1136\/ard.2011.150326","article-title":"Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway","volume":"70","author":"Higgs","year":"2011","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0022","doi-asserted-by":"crossref","DOI":"10.55563\/clinexprheumatol\/1iaqnu","article-title":"Immunisation with Coronavirus-2 vaccines induces potent antibody responses and does not aggravate the lymphocyte compartment of primary Sj\u00f6gren's syndrome patients","author":"Steinmetz","year":"2022","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0023","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.immuni.2018.08.015","article-title":"Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus","volume":"49","author":"Jenks","year":"2018","journal-title":"Immunity"},{"issue":"100","key":"10.1016\/j.imlet.2023.06.005_bib0024","first-page":"30","article-title":"Reduced non-switched memory B cell subsets cause imbalance in B cell repertoire in systemic sclerosis","volume":"34","author":"Simon","year":"2016","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0025","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1001\/archinte.165.20.2337","article-title":"The risk of lymphoma development in autoimmune diseases: a meta-analysis","volume":"165","author":"Zintzaras","year":"2005","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0026","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1101\/sqb.2013.78.020057","article-title":"Establishment and maintenance of B Cell identity","volume":"78","author":"Grosschedl","year":"2013","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0027","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/imm.12009","article-title":"Role of recombination activating genes in the generation of antigen receptor diversity and beyond","volume":"137","author":"Nishana","year":"2012","journal-title":"Immunology"},{"key":"10.1016\/j.imlet.2023.06.005_bib0028","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1126\/science.1086907","article-title":"Predominant autoantibody production by early human B cell precursors","volume":"301","author":"Wardemann","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.imlet.2023.06.005_bib0029","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1172\/JCI78083","article-title":"Checkpoints that control B cell development","volume":"125","author":"Melchers","year":"2015","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.imlet.2023.06.005_bib0030","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.3390\/cells10051190","article-title":"B cell activation and escape of tolerance checkpoints: recent insights from studying autoreactive B cells","volume":"10","author":"Bonasia","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.imlet.2023.06.005_bib0031","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/ni1076","article-title":"Receptor editing is the main mechanism of B cell tolerance toward membrane antigens","volume":"5","author":"Halverson","year":"2004","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0032","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1002\/art.39710","article-title":"Checkpoints for autoreactive B cells in the peripheral blood of lupus patients assessed by flow cytometry","volume":"68","author":"Malkiel","year":"2016","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0033","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1016\/j.jaci.2018.10.041","article-title":"Loss of an IgG plasma cell checkpoint in patients with lupus","volume":"143","author":"Suurmond","year":"2019","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0034","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1038\/ni.1946","article-title":"B cell follicles and antigen encounters of the third kind","volume":"11","author":"Cyster","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0035","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.coi.2006.02.005","article-title":"B cell migration and interactions in the early phase of antibody responses","volume":"18","author":"Okada","year":"2006","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0036","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1126\/science.1125703","article-title":"Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells","volume":"312","author":"Qi","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.imlet.2023.06.005_bib0037","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.it.2019.01.012","article-title":"Programming isotype-specific plasma cell function","volume":"40","author":"Higgins","year":"2019","journal-title":"Trends Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0038","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/imr.12741","article-title":"Extrafollicular responses in humans and SLE","volume":"288","author":"Jenks","year":"2019","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0039","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.4049\/jimmunol.0901690","article-title":"Antigen affinity controls rapid T-dependent antibody production by driving the expansion rather than the differentiation or extrafollicular migration of early plasmablasts","volume":"183","author":"Chan","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0040","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1084\/jem.20061254","article-title":"High affinity germinal center B cells are actively selected into the plasma cell compartment","volume":"203","author":"Phan","year":"2006","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0041","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1038\/ni.1914","article-title":"The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88","volume":"11","author":"He","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0042","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S1074-7613(01)00130-3","article-title":"Regulation of the T-independent humoral response by TACI","volume":"14","author":"von B\u00fclow","year":"2001","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0043","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.130062","article-title":"PD-1hiCXCR5\u2013 T peripheral helper cells promote B cell responses in lupus via MAF and IL-21","volume":"4","author":"Bocharnikov","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.imlet.2023.06.005_bib0044","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1084\/jem.20102065","article-title":"B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells","volume":"208","author":"Lee","year":"2011","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0045","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nature20810","article-title":"Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis","volume":"542","author":"Rao","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.imlet.2023.06.005_bib0046","doi-asserted-by":"crossref","first-page":"7305","DOI":"10.1073\/pnas.1917834117","article-title":"Evidence for a pathogenic role of extrafollicular, IL-10\u2013producing CCR6+B helper T cells in systemic lupus erythematosus","volume":"117","author":"Facciotti","year":"2020","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.imlet.2023.06.005_bib0047","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s41591-018-0254-9","article-title":"A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate","volume":"25","author":"Caielli","year":"2019","journal-title":"Nat. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0048","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.immuni.2016.09.001","article-title":"Germinal center B cell dynamics","volume":"45","author":"Mesin","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0049","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.immuni.2007.07.009","article-title":"Germinal-center organization and cellular dynamics","volume":"27","author":"Allen","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0050","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1084\/jem.20161263","article-title":"The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help","volume":"214","author":"Inoue","year":"2017","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0051","doi-asserted-by":"crossref","first-page":"3967","DOI":"10.1182\/blood-2005-10-4170","article-title":"Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells","volume":"107","author":"Cattoretti","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0052","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.molimm.2018.07.018","article-title":"Mechanics of antigen extraction in the B cell synapse","volume":"101","author":"Spillane","year":"2018","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0053","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1083\/jcb.201607064","article-title":"B cell antigen extraction is regulated by physical properties of antigen-presenting cells","volume":"216","author":"Spillane","year":"2016","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0054","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/35078099","article-title":"B cells acquire antigen from target cells after synapse formation","volume":"411","author":"Batista","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.imlet.2023.06.005_bib0055","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1126\/science.aad3439","article-title":"Visualizing antibody affinity maturation in germinal centers","volume":"351","author":"Tas","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.imlet.2023.06.005_bib0056","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1084\/jem.20161533","article-title":"Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells","volume":"214","author":"Kr\u00e4utler","year":"2017","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0057","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.immuni.2018.03.027","article-title":"T follicular helper cell-germinal center B cell interaction strength regulates entry into plasma cell or recycling germinal center cell fate","volume":"48","author":"Ise","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0058","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.immuni.2015.12.004","article-title":"A temporal switch in the germinal center determines differential output of memory B and plasma cells","volume":"44","author":"Weisel","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0059","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20202489","article-title":"Germinal center\u2013dependent and \u2013independent memory B cells produced throughout the immune response","volume":"218","author":"Viant","year":"2021","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0060","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1084\/jem.20060087","article-title":"Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation","volume":"203","author":"Paus","year":"2006","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0061","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.vaccine.2003.09.001","article-title":"Long-term persistence of anti-HBs after vaccination against HBV: an 18 year experience in health care workers","volume":"22","author":"Floreani","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.imlet.2023.06.005_bib0062","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1128\/jvi.69.3.1895-1902.1995","article-title":"Bone marrow is a major site of long-term antibody production after acute viral infection","volume":"69","author":"Slifka","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0063","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1056\/NEJMoa066092","article-title":"Duration of humoral immunity to common viral and vaccine antigens","volume":"357","author":"Amanna","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0064","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1084\/jem.20011626","article-title":"Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population","volume":"195","author":"O'Connor","year":"2002","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0065","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S1074-7613(00)80541-5","article-title":"Humoral immunity due to long-lived plasma cells","volume":"8","author":"Slifka","year":"1998","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0066","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1126\/science.aaz8432","article-title":"Influenza vaccine\u2013induced human bone marrow plasma cells decline within a year after vaccination","volume":"370","author":"Davis","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.imlet.2023.06.005_bib0067","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1126\/science.aao3859","article-title":"Germinal center antibody mutation trajectories are determined by rapid self\/foreign discrimination","volume":"360","author":"Burnett","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.imlet.2023.06.005_bib0068","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/art.40699","article-title":"Recognition of amino acid motifs, rather than specific proteins, by human plasma cell\u2013derived monoclonal antibodies to posttranslationally modified proteins in rheumatoid arthritis","volume":"71","author":"Steen","year":"2019","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0069","doi-asserted-by":"crossref","first-page":"9727","DOI":"10.1073\/pnas.0803644105","article-title":"Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors","volume":"105","author":"Mietzner","year":"2008","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.imlet.2023.06.005_bib0070","doi-asserted-by":"crossref","first-page":"4926","DOI":"10.4049\/jimmunol.1202263","article-title":"Molecular basis of 9G4 B cell autoreactivity in human systemic lupus erythematosus","volume":"191","author":"Richardson","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0071","doi-asserted-by":"crossref","first-page":"3205","DOI":"10.1172\/JCI24179","article-title":"Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus","volume":"115","author":"Cappione","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.imlet.2023.06.005_bib0072","doi-asserted-by":"crossref","first-page":"3540","DOI":"10.4049\/jimmunol.0803588","article-title":"Ectopic germinal centers are rare in Sj\u00f6gren's syndrome salivary glands and do not exclude autoreactive B cells1","volume":"182","author":"Pottier","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0073","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/nm.2425","article-title":"Foxp3+ follicular regulatory T cells control the germinal center response","volume":"17","author":"Linterman","year":"2011","journal-title":"Nat. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0074","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.morpho.2015.02.001","article-title":"Plasma cell morphology in multiple myeloma and related disorders","volume":"99","author":"Ribourtout","year":"2015","journal-title":"Morphologie"},{"key":"10.1016\/j.imlet.2023.06.005_bib0075","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.202101285","article-title":"Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting","volume":"5","author":"Joyner","year":"2022","journal-title":"Life Sci. Alliance."},{"key":"10.1016\/j.imlet.2023.06.005_bib0076","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/imr.12751","article-title":"Plasma cell differentiation during the germinal center reaction","volume":"288","author":"Ise","year":"2019","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0077","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/imr.12201","article-title":"Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network","volume":"261","author":"Igarashi","year":"2014","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0078","doi-asserted-by":"crossref","first-page":"3989","DOI":"10.1038\/s41467-020-17798-x","article-title":"Antibody-secreting cell destiny emerges during the initial stages of B-cell activation","volume":"11","author":"Scharer","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0079","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/eji.201847517","article-title":"Plasma cells: the programming of an antibody-secreting machine","volume":"49","author":"Tellier","year":"2019","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0080","series-title":"Adv. Immunol","first-page":"57","article-title":"Unraveling the mysteries of plasma cells","author":"Schuh","year":"2020"},{"key":"10.1016\/j.imlet.2023.06.005_bib0081","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/imr.13012","article-title":"The special unfolded protein response in plasma cells","volume":"303","author":"Ricci","year":"2021","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0082","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1016\/j.celrep.2019.10.097","article-title":"IRF4 activity is required in established plasma cells to regulate gene transcription and mitochondrial homeostasis","volume":"29","author":"Low","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.imlet.2023.06.005_bib0083","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.4049\/jimmunol.1201042","article-title":"High rate of antibody secretion is not integral to plasma cell differentiation as revealed by XBP-1 deficiency","volume":"189","author":"Taubenheim","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0084","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/ni.3348","article-title":"Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response","volume":"17","author":"Tellier","year":"2016","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0085","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jim.2009.05.005","article-title":"The third dimension of ELISPOTs: quantifying antibody secretion from individual plasma cells","volume":"346","author":"Bromage","year":"2009","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.imlet.2023.06.005_bib0086","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0090-1229(86)90073-5","article-title":"The human IgA system: a reassessment","volume":"40","author":"Mestecky","year":"1986","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0087","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1586\/1744666X.2014.891439","article-title":"B-cell hyperactivity in primary Sj\u00f6gren's syndrome","volume":"10","author":"Kroese","year":"2014","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0088","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1002\/art.41814","article-title":"Anticentromere antibody levels and isotypes and the development of systemic sclerosis","volume":"73","author":"van Leeuwen","year":"2021","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0089","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1006\/jaut.1998.0236","article-title":"Increased serum levels of immunoglobulins, C-reactive protein, type 1 and type 2 cytokines in patients with mixed connective tissue disease","volume":"11","author":"Bakri Hassan","year":"1998","journal-title":"J. Autoimmun."},{"issue":"1972","key":"10.1016\/j.imlet.2023.06.005_bib0090","first-page":"1386","article-title":"Immunoglobulin synthesis by human lymphoid tissues: normal bone marrow as a major site of IgG production","volume":"109","author":"McMillan","year":"1950","journal-title":"J. Immunol. Baltim. Md"},{"key":"10.1016\/j.imlet.2023.06.005_bib0091","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1084\/jem.20040168","article-title":"Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB\/W mice","volume":"199","author":"Hoyer","year":"2004","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0092","doi-asserted-by":"crossref","first-page":"E6826","DOI":"10.1073\/pnas.1712628115","article-title":"Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis","volume":"115","author":"Huang","year":"2018","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.imlet.2023.06.005_bib0093","doi-asserted-by":"crossref","first-page":"5970","DOI":"10.4049\/jimmunol.165.10.5970","article-title":"Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus","volume":"165","author":"Odendahl","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0094","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1136\/annrheumdis-2018-213615","article-title":"TLR4+CXCR4+ plasma cells drive nephritis development in systemic lupus erythematosus","volume":"77","author":"Ma","year":"2018","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0095","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1365-3083.2010.02475.x","article-title":"Phenotypic diversity of peripheral blood plasma cells in primary Sj\u00f6gren's syndrome: phenotypic diversity of plasma cells in pSS","volume":"73","author":"Szyszko","year":"2011","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0096","doi-asserted-by":"crossref","first-page":"R2","DOI":"10.1186\/ar3220","article-title":"Salivary glands of primary Sjogren's syndrome patients express factors vital for plasma cell survival","volume":"13","author":"Szyszko","year":"2011","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.imlet.2023.06.005_bib0097","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1186\/s13075-014-0500-6","article-title":"Constitutively altered frequencies of circulating follicullar helper T cell counterparts and their subsets in rheumatoid arthritis","volume":"16","author":"Arroyo-Villa","year":"2014","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.imlet.2023.06.005_bib0098","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s13075-018-1569-0","article-title":"Characterization of inflammatory cell infiltrate of scleroderma skin: b cells and skin score progression","volume":"20","author":"Bosello","year":"2018","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.imlet.2023.06.005_bib0099","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/nri3857","article-title":"Antibody-independent functions of B cells: a focus on cytokines","volume":"15","author":"Shen","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0100","first-page":"120","volume":"49","author":"Lino","year":"2018"},{"key":"10.1016\/j.imlet.2023.06.005_bib0101","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/nature12979","article-title":"IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases","volume":"507","author":"Shen","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.imlet.2023.06.005_bib0102","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.immuni.2014.10.016","article-title":"Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation","volume":"41","author":"Matsumoto","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0103","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1182\/blood-2014-09-599159","article-title":"CD24hiCD27+ and plasmablast-like regulatory B cells in human chronic graft-versus-host disease","volume":"125","author":"de Masson","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0104","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/ni.2569","article-title":"Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors ROR\u03b3t and Ahr that leads to IL-17 production by activated B cells","volume":"14","author":"Bermejo","year":"2013","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0105","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1126\/science.1215173","article-title":"Innate response activator B cells protect against microbial sepsis","volume":"335","author":"Rauch","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.imlet.2023.06.005_bib0106","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1002\/1521-4141(200204)32:4<923::AID-IMMU923>3.0.CO;2-1","article-title":"Plasma cells for a lifetime?","volume":"32","author":"Manz","year":"2002","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0107","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1182\/blood.V99.6.2154","article-title":"The heterogeneity shown by human plasma cells from tonsil, blood, and bone marrow reveals graded stages of increasing maturity, but local profiles of adhesion molecule expression","volume":"99","author":"Medina","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0108","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1182\/blood-2004-07-2507","article-title":"Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response","volume":"105","author":"Odendahl","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0109","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1182\/blood-2014-02-555169","article-title":"A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow","volume":"125","author":"Mei","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0110","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.3324\/haematol.2009.018689","article-title":"for the M.S.C. Network (MSCNET), Circulating human B and plasma cells. Age-associated changes in counts and detailed characterization of circulating normal CD138\u2212 and CD138+ plasma cells","volume":"95","author":"Caraux","year":"2010","journal-title":"Haematologica"},{"key":"10.1016\/j.imlet.2023.06.005_bib0111","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1002\/eji.201747019","article-title":"A new staining protocol for detection of murine antibody-secreting plasma cell subsets by flow cytometry","volume":"47","author":"Pracht","year":"2017","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0112","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1002\/eji.201970107","article-title":"Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)","volume":"49","author":"Cossarizza","year":"2019","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0113","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1182\/blood-2017-01-761643","article-title":"CD138 mediates selection of mature plasma cells by regulating their survival","volume":"129","author":"McCarron","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0114","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.critrevonc.2014.12.003","article-title":"Advances in the molecular functions of syndecan-1 (SDC1\/CD138) in the pathogenesis of malignancies","volume":"94","author":"Gharbaran","year":"2015","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0115","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.immuni.2015.06.016","article-title":"Long-lived plasma cells are contained within the CD19\u2212CD38hiCD138+ subset in human bone marrow","volume":"43","author":"Halliley","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0116","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1182\/bloodadvances.2017004481","article-title":"Long-lived plasma cells in human bone marrow can be either CD19+ or CD19\u2013","volume":"1","author":"Brynjolfsson","year":"2017","journal-title":"Blood Adv."},{"key":"10.1016\/j.imlet.2023.06.005_bib0117","doi-asserted-by":"crossref","DOI":"10.1016\/j.trim.2022.101726","article-title":"Bone marrow derived long-lived plasma cell phenotypes are heterogeneous and can change in culture","author":"Mujtahedi","year":"2022","journal-title":"Transpl. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0118","article-title":"Differential transcriptome and development of human peripheral plasma cell subsets","volume":"4","author":"Garimalla","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.imlet.2023.06.005_bib0119","first-page":"42422","article-title":"Maturity of circulating antibody-secreting cells is associated with disease features in primary Sj\u00f6gren's syndrome","author":"Steinmetz","year":"2022","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0120","doi-asserted-by":"crossref","DOI":"10.4049\/jimmunol.1103720","article-title":"In vitro generation of long-lived human plasma cells","author":"Cocco","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0121","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.107982","article-title":"Stromal cell-contact dependent PI3K and APRIL induced NF-\u03baB signaling prevent mitochondrial- and ER stress induced death of memory plasma cells","volume":"32","author":"Cornelis","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.imlet.2023.06.005_bib0122","doi-asserted-by":"crossref","first-page":"3698","DOI":"10.1038\/s41467-018-05853-7","article-title":"Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion","volume":"9","author":"Nguyen","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0123","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/nrneph.2016.20","article-title":"Plasma cells as an innovative target in autoimmune disease with renal manifestations","volume":"12","author":"Hiepe","year":"2016","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0124","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.4049\/jimmunol.169.8.4213","article-title":"The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity","volume":"169","author":"Wols","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0125","doi-asserted-by":"crossref","first-page":"361","DOI":"10.4049\/jimmunol.180.1.361","article-title":"Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice","volume":"180","author":"DiLillo","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0126","doi-asserted-by":"crossref","first-page":"7425","DOI":"10.1073\/pnas.1818242116","article-title":"Salmonella SiiE prevents an efficient humoral immune memory by interfering with IgG+ plasma cell persistence in the bone marrow","volume":"116","author":"M\u00e4nne","year":"2019","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.imlet.2023.06.005_bib0127","doi-asserted-by":"crossref","first-page":"7180","DOI":"10.4049\/jimmunol.1002319","article-title":"Basophils support the survival of plasma cells in mice","volume":"185","author":"Gomez","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0128","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1182\/blood-2009-12-259457","article-title":"Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow","volume":"116","author":"Winter","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0129","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.4049\/jimmunol.0802771","article-title":"Dendritic cells and monocyte\/macrophages that create the IL-6\/APRIL-rich lymph node microenvironments where plasmablasts mature","volume":"182","author":"Mohr","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0130","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1182\/blood-2011-01-332940","article-title":"Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow","volume":"118","author":"Matthes","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0131","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.4049\/jimmunol.180.6.3655","article-title":"Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL","volume":"180","author":"Benson","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0132","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1084\/jem.20031330","article-title":"BCMA is essential for the survival of long-lived bone marrow plasma cells","volume":"199","author":"O'Connor","year":"2004","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0133","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1038\/s41467-021-21994-8","article-title":"Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells","volume":"12","author":"Pascual-Reguant","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0134","first-page":"2887","article-title":"APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa","volume":"118","author":"Huard","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.imlet.2023.06.005_bib0135","doi-asserted-by":"crossref","first-page":"917","DOI":"10.2353\/ajpath.2007.070005","article-title":"Sustained secretion of immunoglobulin by long-lived human tonsil plasma cells","volume":"171","author":"van Laar","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0136","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/imr.12980","article-title":"Fantastic IgA plasma cells and where to find them","volume":"303","author":"Isho","year":"2021","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0137","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/j.1600-0714.1990.tb00810.x","article-title":"Quantification of plasma cells in labial salivary glands: increased expression of IgM in Sjogren's syndrome","volume":"19","author":"Speight","year":"1990","journal-title":"J. Oral Pathol. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0138","first-page":"1","article-title":"Kr\u00fcppel-like factor 2 controls IgA plasma cell compartmentalization and IgA responses","author":"Wittner","year":"2022","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0139","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/j.jid.2019.05.009","article-title":"IgM plasma cells reside in healthy skin and accumulate with chronic inflammation","volume":"139","author":"Wilson","year":"2019","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0140","doi-asserted-by":"crossref","first-page":"4448","DOI":"10.4049\/jimmunol.0801920","article-title":"CXCR4\/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus","volume":"182","author":"Wang","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0141","doi-asserted-by":"crossref","first-page":"11876","DOI":"10.1038\/s41598-022-15293-5","article-title":"Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis","volume":"12","author":"Hardt","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.imlet.2023.06.005_bib0142","doi-asserted-by":"crossref","first-page":"3965","DOI":"10.1182\/blood-2004-08-2992","article-title":"Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells","volume":"105","author":"Muehlinghaus","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0143","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.4049\/jimmunol.169.3.1277","article-title":"Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response","volume":"169","author":"Hauser","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0144","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1365-2249.2010.04290.x","article-title":"Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis","volume":"163","author":"Hosomi","year":"2011","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0145","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1365-2249.2005.02850.x","article-title":"Accumulation of plasma cells expressing CXCR3 in the synovial sublining regions of early rheumatoid arthritis in association with production of Mig\/CXCL9 by synovial fibroblasts","volume":"141","author":"Tsubaki","year":"2005","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0146","doi-asserted-by":"crossref","first-page":"3211","DOI":"10.1002\/art.20519","article-title":"Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus","volume":"50","author":"Hutloff","year":"2004","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.imlet.2023.06.005_bib0147","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0008-8749(81)90042-3","article-title":"Migration of IgA-bearing lymphocytes into salivary glands","volume":"63","author":"Jackson","year":"1981","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0148","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1002\/1529-0131(199812)41:12<2238::AID-ART20>3.0.CO;2-V","article-title":"Detection of anti-Ro\/SSA and anti-La\/SSB autoantibody-producing cells in salivary glands from patients with Sj\u00f6gren's syndrome","volume":"41","author":"Tengn\u00e9r","year":"1998","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.imlet.2023.06.005_bib0149","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1080\/030097498440831","article-title":"Expression of the mucosal lymphocyte integrin aE\u00df7 and its ligand E-cadherin in salivary glands of patients with Sj\u00f6gren's syndrome","volume":"27","author":"Kroneld H. Carlsten","year":"1998","journal-title":"Scand. J. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0150","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0003-9969(99)00024-2","article-title":"Cytokine-mediated stimulation of laminin expression and cell-growth arrest in a human submandibular gland duct-cell line (HSG)","volume":"44","author":"Daniels","year":"1999","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0151","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.jaut.2012.01.002","article-title":"Pathogenesis of Sj\u00f6gren's syndrome: what we know and what we should learn","volume":"39","author":"Tzioufas","year":"2012","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0152","first-page":"612","article-title":"Effect of sulfasalazine on B cell hyperactivity in patients with rheumatoid arthritis","volume":"21","author":"Imai","year":"1994","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0153","first-page":"59","article-title":"Polyclonal B lymphocyte activation in progressive systemic sclerosis","volume":"29","author":"Famularo","year":"1989","journal-title":"J. Clin. Lab. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0154","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3109\/08830185.2013.786712","article-title":"Aberrant B cell selection and activation in systemic lupus erythematosus","volume":"32","author":"Kil","year":"2013","journal-title":"Int. Rev. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0155","series-title":"Pathog. Syst. Lupus Erythematosus","first-page":"9","article-title":"Hallmark of systemic lupus erythematosus: role of B cell hyperactivity","author":"Vincent","year":"2021"},{"key":"10.1016\/j.imlet.2023.06.005_bib0156","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1196\/annals.1313.004","article-title":"BAFF overexpression is associated with autoantibody production in autoimmune diseases","volume":"1050","author":"Pers","year":"2005","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.imlet.2023.06.005_bib0157","first-page":"22","article-title":"Serial estimation of interleukin 6 as a measure of systemic disease in rheumatoid arthritis","volume":"19","author":"Dasgupta","year":"1992","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0158","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0889-857X(05)70296-9","article-title":"Immunopathogenesis of systemic sclerosis","volume":"22","author":"White","year":"1996","journal-title":"Rheum. Dis. Clin."},{"key":"10.1016\/j.imlet.2023.06.005_bib0159","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/cei.13385","article-title":"Serum immunoglobulin free light chain levels in systemic autoimmune rheumatic diseases","volume":"199","author":"Gulli","year":"2020","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0160","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.autrev.2014.07.003","article-title":"Serum free light chains of immunoglobulins as biomarkers for systemic sclerosis characteristics, activity and severity","volume":"13","author":"Lanteri","year":"2014","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0161","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1136\/annrheumdis-2015-207392","article-title":"The interferon type I signature is present in systemic sclerosis before overt fibrosis and might contribute to its pathogenesis through high BAFF gene expression and high collagen synthesis","volume":"75","author":"Brkic","year":"2016","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0162","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/s41584-021-00605-2","article-title":"Epithelial\u2013immune cell interplay in primary Sj\u00f6gren syndrome salivary gland pathogenesis","volume":"17","author":"Verstappen","year":"2021","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0163","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/s41584-021-00588-0","article-title":"Skin\u2013kidney crosstalk in SLE","volume":"17","author":"Kolios","year":"2021","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0164","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nrneph.2015.33","article-title":"Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis","volume":"11","author":"Mohan","year":"2015","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0165","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.autrev.2010.08.016","article-title":"Systemic lupus erythematosus: clinical presentations","volume":"10","author":"Smith","year":"2010","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0166","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1093\/rheumatology\/keab781","article-title":"Histopathology, salivary flow and ultrasonography of the parotid gland: three complementary measurements in primary Sj\u00f6gren's syndrome","volume":"61","author":"Mossel","year":"2022","journal-title":"Rheumatology"},{"issue":"118","key":"10.1016\/j.imlet.2023.06.005_bib0167","first-page":"42","article-title":"Presence of intraepithelial B-lymphocytes is associated with the formation of lymphoepithelial lesions in salivary glands of primary Sj\u00f6gren's syndrome patients","volume":"37","author":"van Ginkel","year":"2019","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0168","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1586\/1744666X.2016.1109449","article-title":"on behalf of the EULAR Sj\u00f6gren syndrome task force, early diagnosis of primary Sj\u00f6gren's syndrome: EULAR-SS task force clinical recommendations","volume":"12","author":"Brito-Zer\u00f3n","year":"2016","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0169","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2021.102648","article-title":"A biomarker for lymphoma development in Sjogren's syndrome: salivary gland focus score","volume":"121","author":"Chatzis","year":"2021","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0170","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/s41584-021-00634-x","article-title":"Current and future therapies for primary Sj\u00f6gren syndrome","volume":"17","author":"Seror","year":"2021","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0171","doi-asserted-by":"crossref","first-page":"v69","DOI":"10.1093\/rheumatology\/keaa403","article-title":"Treating systemic lupus erythematosus in the 21st century: new drugs and new perspectives on old drugs","volume":"59","author":"Ruiz-Irastorza","year":"2020","journal-title":"Rheumatology"},{"key":"10.1016\/j.imlet.2023.06.005_bib0172","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.autrev.2014.10.003","article-title":"A volcanic explosion of autoantibodies in systemic lupus erythematosus: a diversity of 180 different antibodies found in SLE patients","volume":"14","author":"Yaniv","year":"2015","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0173","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jaut.2012.03.001","article-title":"Subgroups of Sj\u00f6gren syndrome patients according to serological profiles","volume":"39","author":"Bournia","year":"2012","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0174","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1056\/NEJMoa021933","article-title":"Development of autoantibodies before the clinical onset of systemic lupus erythematosus","volume":"349","author":"Arbuckle","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0175","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1002\/art.39214","article-title":"Prediction of Sj\u00f6gren's syndrome years before diagnosis and identification of patients with early onset and severe disease course by autoantibody profiling","volume":"67","author":"Theander","year":"2015","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0176","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1001\/jama.2013.278448","article-title":"Autoantibodies present before symptom onset in primary Sj\u00f6gren syndrome","volume":"310","author":"Jonsson","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.imlet.2023.06.005_bib0177","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1172\/JCI78084","article-title":"Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity","volume":"125","author":"Suurmond","year":"2015","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.imlet.2023.06.005_bib0178","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/s41584-020-0480-7","article-title":"New insights into the role of antinuclear antibodies in systemic lupus erythematosus","volume":"16","author":"Pisetsky","year":"2020","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0179","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3109\/08916934.2010.541170","article-title":"Nephritogenic antibodies bind in glomeruli through interaction with exposed chromatin fragments and not with renal cross-reactive antigens","volume":"44","author":"Mjelle","year":"2011","journal-title":"Autoimmunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0180","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1093\/rheumatology\/39.12.1316","article-title":"Prognostic parameters for flare in systemic lupus erythematosus","volume":"39","author":"Mirzayan","year":"2000","journal-title":"Rheumatology"},{"key":"10.1016\/j.imlet.2023.06.005_bib0181","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1136\/ard.2008.094508","article-title":"Are laboratory tests useful for monitoring the activity of lupus nephritis? A 6-year prospective study in a cohort of 228 patients with lupus nephritis","volume":"68","author":"Moroni","year":"2009","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0182","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1136\/ard.56.11.661","article-title":"The predictive value of fluctuations in IgM and IgG class anti-dsDNA antibodies for relapses in systemic lupus erythematosus. A prospective long term observation","volume":"56","author":"Bootsma","year":"1997","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0183","doi-asserted-by":"crossref","first-page":"7538","DOI":"10.1073\/pnas.95.13.7538","article-title":"Transfer of human serum IgG to nonobese diabetic Ig\u03bcnull mice reveals a role for autoantibodies in the loss of secretory function of exocrine tissues in Sj\u00f6gren's syndrome","volume":"95","author":"Robinson","year":"1998","journal-title":"Proc. Natl. Acad. Sci"},{"key":"10.1016\/j.imlet.2023.06.005_bib0184","doi-asserted-by":"crossref","first-page":"8409","DOI":"10.4049\/jimmunol.175.12.8409","article-title":"Immunization with short peptides from the 60-kDa Ro antigen recapitulates the serological and pathological findings as well as the salivary gland dysfunction of Sj\u00f6gren's syndrome","volume":"175","author":"Scofield","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0185","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1365-2249.2009.04036.x","article-title":"Activation profile of Toll-like receptors of peripheral blood lymphocytes in patients with systemic lupus erythematosus","volume":"159","author":"Wong","year":"2010","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0186","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.tripleo.2010.01.006","article-title":"Expression of Toll-like receptors 7, 8, and 9 in primary Sj\u00f6gren's syndrome","volume":"109","author":"Zheng","year":"2010","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodontol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0187","doi-asserted-by":"crossref","first-page":"3969","DOI":"10.1182\/blood-2008-10-185421","article-title":"BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation","volume":"113","author":"Eckl-Dorna","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0188","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/ncomms1769","article-title":"BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-\u03baB pathway","volume":"3","author":"Pone","year":"2012","journal-title":"Nat. Commun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0189","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1002\/art.37828","article-title":"Expansion of autoreactive unresponsive CD21\u2212\/low B cells in Sj\u00f6gren's syndrome\u2013associated lymphoproliferation","volume":"65","author":"Saadoun","year":"2013","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.imlet.2023.06.005_bib0190","first-page":"10","article-title":"Single cell based phosphorylation profiling identifies alterations in toll-like receptor 7 and 9 signaling in patients with primary Sj\u00f6gren's syndrome","author":"Davies","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0191","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1038\/s41467-018-03750-7","article-title":"IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE","volume":"9","author":"Wang","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.imlet.2023.06.005_bib0192","first-page":"11","article-title":"CD11c+ B cells are mainly memory cells, precursors of antibody secreting cells in healthy donors","author":"Golinski","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0193","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.semarthrit.2012.07.003","article-title":"The role of ectopic germinal centers in the immunopathology of primary Sj\u00f6gren's syndrome: a systematic review","volume":"42","author":"Risselada","year":"2013","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.imlet.2023.06.005_bib0194","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2021.102980","article-title":"Interplay of immune and kidney resident cells in the formation of tertiary lymphoid structures in lupus nephritis","volume":"20","author":"Jamaly","year":"2021","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0195","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1177\/0961203314567750","article-title":"Circulating CXCR5+CD4+helper T cells in systemic lupus erythematosus patients share phenotypic properties with germinal center follicular helper T cells and promote antibody production","volume":"24","author":"Zhang","year":"2015","journal-title":"Lupus"},{"key":"10.1016\/j.imlet.2023.06.005_bib0196","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.4049\/jimmunol.1401190","article-title":"Cutting edge: circulating plasmablasts induce the differentiation of human T follicular helper cells via IL-6 production","volume":"194","author":"Chavele","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0197","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1136\/annrheumdis-2020-217646","article-title":"Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sj\u00f6gren's syndrome with ectopic germinal centres and MALT lymphoma","volume":"79","author":"Pontarini","year":"2020","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0198","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2020-001442","article-title":"Association between T follicular helper cells and T peripheral helper cells with B-cell biomarkers and disease activity in primary Sj\u00f6gren syndrome","volume":"7","author":"Dupr\u00e9","year":"2021","journal-title":"RMD Open"},{"key":"10.1016\/j.imlet.2023.06.005_bib0199","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.cell.2016.03.008","article-title":"Personalized immunomonitoring uncovers molecular networks that stratify lupus patients","volume":"165","author":"Banchereau","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.imlet.2023.06.005_bib0200","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1016\/j.cell.2022.07.021","article-title":"Distinct transcriptome architectures underlying lupus establishment and exacerbation","volume":"185","author":"Nakano","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.imlet.2023.06.005_bib0201","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.127885","article-title":"Patterns of ANA+ B cells for SLE patient stratification","volume":"4","author":"Suurmond","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.imlet.2023.06.005_bib0202","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1136\/ard.2008.096495","article-title":"HLA-DRhigh\/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus","volume":"69","author":"Jacobi","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0203","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1056\/NEJMoa2023325","article-title":"Targeting CD38 with daratumumab in refractory systemic lupus erythematosus","volume":"383","author":"Ostendorf","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0204","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/ni.3175","article-title":"Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus","volume":"16","author":"Tipton","year":"2015","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0205","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1002\/art.22197","article-title":"Expansion of toll-like receptor 9\u2013expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process","volume":"54","author":"Papadimitraki","year":"2006","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.imlet.2023.06.005_bib0206","doi-asserted-by":"crossref","first-page":"765","DOI":"10.3109\/08860229609047705","article-title":"The role of the kidney biopsy in the treatment of lupus nephritis","volume":"18","author":"Kashgarian","year":"1996","journal-title":"Ren. Fail."},{"key":"10.1016\/j.imlet.2023.06.005_bib0207","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1002\/art.41703","article-title":"Molecular signatures of kidney antibody\u2013secreting cells in lupus patients with active nephritis upon immunosuppressive therapy","volume":"73","author":"Crickx","year":"2021","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0208","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1136\/annrheumdis-2013-203455","article-title":"Autoantibodies from long-lived \u2018memory\u2019 plasma cells of NZB\/W mice drive immune complex nephritis","volume":"72","author":"Cheng","year":"2013","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0209","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1038\/s41590-019-0398-x","article-title":"Accelerating Medicines Partnership in SLE network, the immune cell landscape in kidneys of patients with lupus nephritis","volume":"20","author":"Arazi","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0210","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1016\/j.jaci.2016.01.024","article-title":"Cytometry by time-of-flight immunophenotyping identifies a blood Sj\u00f6gren's signature correlating with disease activity and glandular inflammation","volume":"137","author":"Mingueneau","year":"2016","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0211","first-page":"1988","article-title":"CD4+CXCR5+ follicular helper T cells in salivary gland promote B cells maturation in patients with primary Sjogren's syndrome","volume":"7","author":"Jin","year":"2014","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0212","first-page":"keac304","article-title":"TOX promotes follicular helper T cell differentiation in patients with primary Sj\u00f6gren's syndrome","author":"Liu","year":"2022","journal-title":"Rheumatology"},{"key":"10.1016\/j.imlet.2023.06.005_bib0213","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.coi.2018.10.008","article-title":"The long and the short of it: insights into the cellular source of autoantibodies as revealed by B cell depletion therapy","volume":"55","author":"Hale","year":"2018","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0214","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/art.22536","article-title":"Improvement of Sj\u00f6gren's syndrome after two infusions of rituximab (anti-CD20)","volume":"57","author":"Devauchelle-Pensec","year":"2007","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.imlet.2023.06.005_bib0215","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3899\/jrheum.160313","article-title":"B cell depletion therapy normalizes circulating follicular Th cells in primary Sj\u00f6gren syndrome","volume":"44","author":"Verstappen","year":"2017","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0216","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/nrrheum.2016.208","article-title":"Refining the classification criteria for primary Sj\u00f6gren syndrome","volume":"13","author":"Vissink","year":"2017","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0217","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1080\/08916934.2019.1684475","article-title":"Autoantigen-specific B cells and plasma cells are prominent in areas of fatty infiltration in salivary glands of patients with primary Sj\u00f6gren's syndrome","volume":"52","author":"Skarstein","year":"2019","journal-title":"Autoimmunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0218","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3109\/08916934.2015.1079820","article-title":"Non-proliferating plasma cells detected in the salivary glands and bone marrow of autoimmune NOD.B10.H2b mice, a model for primary Sj\u00f6gren's syndrome","volume":"49","author":"Szyszko","year":"2016","journal-title":"Autoimmunity"},{"key":"10.1016\/j.imlet.2023.06.005_bib0219","article-title":"Monoclonal gammopathy and risk of lymphoma and multiple myeloma in patients with primary Sj\u00f6gren's syndrome","author":"Tomi","year":"2015","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0220","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00296-020-04522-7","article-title":"Prevalence and clinical presentation of lymphoproliferative disorder in patients with primary Sj\u00f6gren's syndrome","volume":"40","author":"Sebastian","year":"2020","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.imlet.2023.06.005_bib0221","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1158\/1055-9965.EPI-13-0695","article-title":"Prior autoimmune disease and risk of monoclonal gammopathy of undetermined significance and multiple myeloma: a systematic review","volume":"23","author":"McShane","year":"2014","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0222","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1136\/annrheumdis-2019-216287","article-title":"Increased risk of multiple myeloma in primary Sj\u00f6gren's syndrome is limited to individuals with Ro\/SSA and La\/SSB autoantibodies","volume":"79","author":"Mofors","year":"2020","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0223","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1136\/annrheumdis-2011-201189","article-title":"Persistence of immunoglobulin-producing cells in parotid salivary glands of patients with primary Sj\u00f6gren's syndrome after B cell depletion therapy","volume":"71","author":"Hamza","year":"2012","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0224","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1136\/annrheumdis-2021-221604","article-title":"Proteogenomic analysis of the autoreactive B cell repertoire in blood and tissues of patients with Sj\u00f6gren's syndrome","volume":"81","author":"Broeren","year":"2022","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0225","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s10555-017-9707-8","article-title":"The proteasome and proteasome inhibitors in multiple myeloma","volume":"36","author":"Gandolfi","year":"2017","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/j.imlet.2023.06.005_bib0226","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1136\/annrheumdis-2014-206016","article-title":"The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus","volume":"74","author":"Alexander","year":"2015","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2023.06.005_bib0227","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1002\/eji.201847492","article-title":"Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors","volume":"48","author":"Alexander","year":"2018","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0228","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.3390\/cancers12092540","article-title":"Non-hematologic toxicity of bortezomib in multiple myeloma: the neuromuscular and cardiovascular adverse effects","volume":"12","author":"Pancheri","year":"2020","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.imlet.2023.06.005_bib0229","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/RHU.0000000000000210","article-title":"Refractory primary Sj\u00f6gren syndrome successfully treated with bortezomib","volume":"21","author":"Jakez-Ocampo","year":"2015","journal-title":"JCR J. Clin. Rheumatol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0230","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1182\/blood-2017-06-740944","article-title":"CD38 antibodies in multiple myeloma: back to the future","volume":"131","author":"van de Donk","year":"2018","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0231","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1056\/NEJMoa1505654","article-title":"Elotuzumab therapy for relapsed or refractory multiple myeloma","volume":"373","author":"Lonial","year":"2015","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0232","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1470-2045(19)30788-0","article-title":"Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study","volume":"21","author":"Lonial","year":"2020","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0233","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.3389\/fimmu.2018.02551","article-title":"Mechanisms of NK cell activation and clinical activity of the therapeutic SLAMF7 antibody, elotuzumab in multiple myeloma","volume":"9","author":"Campbell","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0234","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.1182\/blood-2017-04-778423","article-title":"SLAMF7-CAR T cells eliminate myeloma and confer selective fratricide of SLAMF7+ normal lymphocytes","volume":"130","author":"Gogishvili","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0235","doi-asserted-by":"crossref","first-page":"4076","DOI":"10.18632\/oncotarget.27792","article-title":"T-cell redirecting bispecific antibodies targeting BCMA for the treatment of multiple myeloma","volume":"11","author":"Verkleij","year":"2020","journal-title":"Oncotarget"},{"key":"10.1016\/j.imlet.2023.06.005_bib0236","first-page":"keac393","article-title":"Effective and safe treatment of anti-CD38 therapy in systemic lupus erythematosus\u2013associated refractory cerebral vasculitis induces immune tolerance","author":"Yalcin Mutlu","year":"2022","journal-title":"Rheumatology"},{"key":"10.1016\/j.imlet.2023.06.005_bib0237","doi-asserted-by":"crossref","first-page":"e302","DOI":"10.3324\/haematol.2019.231860","article-title":"Effect of daratumumab on normal plasma cells, polyclonal immunoglobulin levels, and vaccination responses in extensively pre-treated multiple myeloma patients","volume":"105","author":"Frerichs","year":"2020","journal-title":"Haematologica"},{"key":"10.1016\/j.imlet.2023.06.005_bib0238","article-title":"Durable remissions with BCMA-specific chimeric antigen receptor (CAR)-modified T cells in patients with refractory\/relapsed multiple myeloma","volume":"35","author":"(Xiaohu) Fan","year":"2017","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0239","doi-asserted-by":"crossref","first-page":"9543","DOI":"10.1073\/pnas.1819745116","article-title":"Exploratory trial of a biepitopic CAR T-targeting B cell maturation antigen in relapsed\/refractory multiple myeloma","volume":"116","author":"Xu","year":"2019","journal-title":"Proc. Natl. Acad. Sci"},{"key":"10.1016\/j.imlet.2023.06.005_bib0240","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1182\/blood-2016-04-711903","article-title":"T cells expressing an anti\u2013B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma","volume":"128","author":"Ali","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0241","first-page":"1","article-title":"Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus","author":"Mackensen","year":"2022","journal-title":"Nat. Med."},{"key":"10.1016\/j.imlet.2023.06.005_bib0242","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1182\/blood-2016-01-694356","article-title":"Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy","volume":"128","author":"Bhoj","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2023.06.005_bib0243","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1002\/eji.201948144","article-title":"Selective depletion of plasma cells in vivo based on the specificity of their secreted antibodies","volume":"50","author":"Cheng","year":"2020","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.imlet.2023.06.005_bib0244","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/eji.201444993","article-title":"Selection and depletion of plasma cells based on the specificity of the secreted antibody","volume":"45","author":"Taddeo","year":"2015","journal-title":"Eur. J. Immunol."}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247823001086?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247823001086?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T07:42:35Z","timestamp":1759045355000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247823001086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":244,"alternative-id":["S0165247823001086"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2023.06.005","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeting plasma cells in systemic autoimmune rheumatic diseases \u2013 Promises and pitfalls","name":"articletitle","label":"Article Title"},{"value":"Immunology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imlet.2023.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier B.V. on behalf of European Federation of Immunological Societies.","name":"copyright","label":"Copyright"}]}}