{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T17:03:57Z","timestamp":1781024637128,"version":"3.54.1"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006507","name":"Funda\u00e7\u00e3o Oswaldo Cruz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006507","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.imlet.2025.107098","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T16:18:37Z","timestamp":1759421917000},"page":"107098","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Immunological features driving distinct repigmentation patterns in patients with stable vitiligo submitted to the autologous keratinocyte\/melanocyte transplantation"],"prefix":"10.1016","volume":"277","author":[{"given":"Bruna Estef\u00e2nia Diniz","family":"Frias","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta Oliveira","family":"Prado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9232-7857","authenticated-orcid":false,"given":"Mariana Gontijo","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nath\u00e1lia Werneck C\u00e9zar de","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Fortes de","family":"Ara\u00fajo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4466-8868","authenticated-orcid":false,"given":"Liliane Martins dos","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila Gontijo","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila Bechara","family":"Kall\u00e1s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria S\u00edlvia Laborne Alves de","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8691-7669","authenticated-orcid":false,"given":"Ismael Artur","family":"Costa-Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0248-1138","authenticated-orcid":false,"given":"Joaquim Pedro","family":"Brito-de-Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel Basques","family":"Caligiorne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Ant\u00f4nio","family":"Pascoal-Xavier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Peruhype-Magalh\u00e3es","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Gontijo","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9a","family":"Teixeira-Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5494-4889","authenticated-orcid":false,"given":"Olindo Assis","family":"Martins-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2025.107098_bib0001","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1346-8138.2010.01139.x","article-title":"Vitiligo: a review of the published work","volume":"38","author":"Yaghoobi","year":"2011","journal-title":"J. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0002","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1111\/bjd.13423","article-title":"Hypochromic vitiligo: delineation of a new entity","volume":"172","author":"Ezzedine","year":"2015","journal-title":"Br J. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0003","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1146\/annurev-immunol-100919-023531","article-title":"Vitiligo: mechanisms of Pathogenesis and Treatment","volume":"38","author":"Frisoli","year":"2020","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.imlet.2025.107098_bib0004","doi-asserted-by":"crossref","first-page":"216","DOI":"10.3109\/14764172.2014.1003241","article-title":"Carbon dioxide laser plus topical 5-fluorouracil: a new combination therapeutic modality for acral vitiligo","volume":"17","author":"Mohamed","year":"2015","journal-title":"J. Cosmet. Laser. Ther."},{"key":"10.1016\/j.imlet.2025.107098_bib0005","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1111\/j.1365-4632.2005.02226.x","article-title":"Long-term follow-up study of 142 patients with vitiligo vulgaris treated by autologous, non-cultured melanocyte-keratinocyte cell transplantation","volume":"44","author":"Mulekar","year":"2005","journal-title":"Int. J. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0006","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1046\/j.1365-4362.2003.01628.x","article-title":"Melanocyte-keratinocyte cell transplantation for stable vitiligo","volume":"42","author":"Mulekar","year":"2003","journal-title":"Int. J. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0007","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.jaad.2011.05.002","article-title":"Melanocyte-keratinocyte transplantation procedure in the treatment of vitiligo: the experience of an academic medical center in the United States","volume":"66","author":"Huggins","year":"2012","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0008","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/196537","article-title":"Immunological Parameters Associated With Vitiligo Treatments: a Literature Review Based on Clinical Studies","author":"Abreu","year":"2015","journal-title":"Autoimmune Dis."},{"key":"10.1016\/j.imlet.2025.107098_bib0009","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1590\/abd1806-4841.20175700","article-title":"Evaluation of treatment response to autologous transplantation of noncultured melanocyte\/keratinocyte cell suspension in patients with stable vitiligo","volume":"92","author":"Ramos","year":"2017","journal-title":"An Bras. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0010","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.abd.2021.09.008","article-title":"Update on the pathogenesis of vitiligo","volume":"97","author":"Marchioro","year":"2022","journal-title":"An Bras. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0011","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1080\/09546634.2020.1793885","article-title":"Outcomes of autologous non-cultured melanocyte keratinocyte transplantation in vitiligo and nevus depigmentosus","volume":"33","author":"Sritanyarat","year":"2022","journal-title":"J. Dermatolog. Treat."},{"key":"10.1016\/j.imlet.2025.107098_bib0012","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/DSS.0000000000001641","article-title":"Laser Ablation of the Recipient Area With Platelet-Rich Plasma-Enriched Epidermal Suspension Transplant in Vitiligo Surgery: a Pilot Study","volume":"45","author":"Garg","year":"2019","journal-title":"Dermatol. Surg."},{"key":"10.1016\/j.imlet.2025.107098_bib0013","first-page":"419","article-title":"Noncultured Epidermal Suspension in Vitiligo-A Review of Origins, Modifications, and Innovations for this","volume":"19","author":"Mhatre","year":"2021","journal-title":"Surgic. Masterstrok. Skinmed."},{"key":"10.1016\/j.imlet.2025.107098_bib0014","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.jaad.2016.04.007","article-title":"Twelve-month and sixty-month outcomes of noncultured cellular grafting for vitiligo","volume":"75","author":"Gan","year":"2016","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0015","doi-asserted-by":"crossref","first-page":"521","DOI":"10.2147\/CCID.S151503","article-title":"Autologous non-cultured melanocyte-keratinocyte transplantation in the treatment of vitiligo: patient selection and perspectives","volume":"11","author":"Bassiouny","year":"2018","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0016","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1111\/j.1365-2230.2011.04065.x","article-title":"Noncultured epidermal suspension transplantation for the treatment of stable vitiligo in children and adolescents","volume":"36","author":"Sahni","year":"2011","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0017","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.abd.2021.08.003","article-title":"Treatment of recalcitrant vitiligo by autologous non-cultured and trypsinized melanocyte grafting in the west of Iran","volume":"97","author":"Ghorbani","year":"2022","journal-title":"An Bras Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0018","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1590\/abd1806-4841.20132054","article-title":"Non-cultured melanocyte\/keratinocyte transplantation for the treatment of stable vitiligo on the face: report of two cases","volume":"88","author":"Ramos","year":"2013","journal-title":"An Bras. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0019","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/exd.14157","article-title":"Decreased suppression of CD8+ and CD4+ T cells by peripheral regulatory T cells in generalized vitiligo due to reduced NFATC1 and FOXP3 proteins","volume":"29","author":"Giri","year":"2020","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0020","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1111\/bjd.12691","article-title":"Inflammasome activation and vitiligo\/nonsegmental vitiligo progression","volume":"170","author":"Marie","year":"2014","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0021","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-019-09963-8","article-title":"Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo","volume":"10","author":"M.K.Tulic","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.imlet.2025.107098_bib0022","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.det.2016.11.007","article-title":"Medical and Maintenance Treatments for Vitiligo","volume":"35","author":"Passeron","year":"2017","journal-title":"Dermatol. Clin."},{"key":"10.1016\/j.imlet.2025.107098_bib0023","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00592-008-0040-0","article-title":"Neutrophil surface expression of CD11b and CD62L in diabetic microangiopathy","volume":"45","author":"Mastej","year":"2008","journal-title":"Acta Diabetol."},{"key":"10.1016\/j.imlet.2025.107098_bib0024","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.250340","article-title":"L-selectin regulates human neutrophil transendothelial migration","volume":"134","author":"Rahman","year":"2021","journal-title":"J. Cell Sci."},{"issue":"12","key":"10.1016\/j.imlet.2025.107098_bib0025","article-title":"Targeting Innate Immunity to Combat Cutaneous Stress: the Vitiligo Perspective","volume":"14","author":"Boniface","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.imlet.2025.107098_bib0026","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00403-019-01996-9","article-title":"Predominant role of innate pro-inflammatory cytokines in vitiligo disease","volume":"312","author":"Gholijani","year":"2020","journal-title":"Arch Dermatol. Res."},{"key":"10.1016\/j.imlet.2025.107098_bib0027","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1038\/jid.2009.32","article-title":"Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients","volume":"129","author":"Van den Boorn","year":"2009","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0028","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1111\/j.1365-2133.2010.10014.x","article-title":"Long-term results of noncultured epidermal cellular grafting in vitiligo, halo naevi, piebaldism and naevus depigmentosus","volume":"163","author":"Van Geel","year":"2010","journal-title":"British J. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0029","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/518090","article-title":"Nonsegmental vitiligo and autoimmune mechanism","author":"Oiso","year":"2011","journal-title":"Dermatol. Res. Pract."},{"key":"10.1016\/j.imlet.2025.107098_bib0030","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1111\/j.1365-2133.2012.10886.x","article-title":"Study of clinical, biochemical and immunological factors determining stability of disease in patients with generalized vitiligo undergoing melanocyte transplantation","volume":"166","author":"Rao","year":"2012","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0031","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jid.2016.09.016","article-title":"Keratinocyte-Derived Chemokines Orchestrate T-Cell Positioning in the Epidermis during Vitiligo and May Serve as Biomarkers of Disease","volume":"137","author":"Richmond","year":"2017","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0032","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/1744666X.2019.1550358","article-title":"Cytokines: the yin and yang of vitiligo pathogenesis","volume":"15","author":"Singh","year":"2019","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.imlet.2025.107098_bib0033","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1038\/jid.2009.143","article-title":"Genetic polymorphisms of glutathione S-transferase and risk of vitiligo in the Chinese population","volume":"129","author":"Liu","year":"2009","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.imlet.2025.107098_bib0034","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.154585","article-title":"Multimodal analyses of vitiligo skin identify tissue characteristics of stable disease","volume":"7","author":"Shiu","year":"2022","journal-title":"JCI Insight."},{"key":"10.1016\/j.imlet.2025.107098_bib0035","unstructured":"K. Wolf, R.A. Johnson, A.P. Saavedra, E.K. Roh, Dermatologia De Fitzpatrick : atlas e Texto. 7th ed. Porto Alegre, 2015."},{"key":"10.1016\/j.imlet.2025.107098_bib0036","first-page":"1027","article-title":"Autologous cultured melanocytes in vitiligo treatment","volume":"33","author":"Czajkowski","year":"2007","journal-title":"Dermatol. Surg."},{"key":"10.1016\/j.imlet.2025.107098_bib0037","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/cei\/uxab002","article-title":"Patho-immunological mechanisms of vitiligo: the role of the innate and adaptive immunities and environmental stress factors","volume":"207","author":"Faraj","year":"2022","journal-title":"Clin. Exp. Immunol."}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247825001312?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247825001312?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T16:51:57Z","timestamp":1781023917000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247825001312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":37,"alternative-id":["S0165247825001312"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2025.107098","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immunological features driving distinct repigmentation patterns in patients with stable vitiligo submitted to the autologous keratinocyte\/melanocyte transplantation","name":"articletitle","label":"Article Title"},{"value":"Immunology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imlet.2025.107098","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 European Federation of Immunological Societies. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107098"}}