{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:01:09Z","timestamp":1786114869472,"version":"build-2736575974"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K11618"],"award-info":[{"award-number":["24K11618"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.imlet.2025.107123","type":"journal-article","created":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T15:14:39Z","timestamp":1765120479000},"page":"107123","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Potential link between COVID-19 infection\/vaccination and the onsets of TAFRO syndrome and idiopathic multicentric castleman disease"],"prefix":"10.1016","volume":"278","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6647-7130","authenticated-orcid":false,"given":"Masataka","family":"Umeda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1817-396X","authenticated-orcid":false,"given":"Lamiaa","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayaka","family":"Umetsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuna","family":"Otsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7008-2334","authenticated-orcid":false,"given":"Yushiro","family":"Endo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0036-2039","authenticated-orcid":false,"given":"Toshimasa","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichi","family":"Fukui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remi","family":"Sumiyoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Koga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Kawakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2025.107123_bib0001","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1002\/ajh.26292","article-title":"Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease","volume":"96","author":"Nishimura","year":"2021","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.imlet.2025.107123_bib0002","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s12185-020-03008-3","article-title":"Optimal treatments for TAFRO syndrome: a retrospective surveillance study in Japan","volume":"113","author":"Fujimoto","year":"2021","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.imlet.2025.107123_bib0003","article-title":"Expert perspective: diagnosis and treatment of Castleman disease","author":"Chen","year":"2025","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.imlet.2025.107123_bib0004","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1002\/ajh.27612","article-title":"Exploring the clinical diversity of Castleman Disease and TAFRO Syndrome: a Japanese multicenter study on lymph node distribution patterns","volume":"100","author":"Otsuka","year":"2025","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.imlet.2025.107123_bib0005","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1182\/bloodadvances.2024014391","article-title":"Characterizing the heterogeneity of Castleman disease and oligocentric subtype: findings from the ACCELERATE registry","volume":"9","author":"Pierson","year":"2025","journal-title":"Blood Adv."},{"key":"10.1016\/j.imlet.2025.107123_bib0006","first-page":"12","article-title":"TAFRO syndrome and COVID-19","author":"Tane","year":"2024","journal-title":"Biomedicines"},{"key":"10.1016\/j.imlet.2025.107123_bib0007","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1337406","article-title":"New-onset autoimmune disease after COVID-19","volume":"15","author":"Hileman","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.imlet.2025.107123_bib0008","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1080\/14760584.2023.2188950","article-title":"Effectiveness of mRNA COVID-19 vaccines against symptomatic SARS-CoV-2 infections during the SARS-CoV-2 Omicron BA.1 and BA.2 epidemic in Japan: vaccine effectiveness real-time surveillance for SARS-CoV-2 (VERSUS)","volume":"22","author":"Maeda","year":"2023","journal-title":"Expert. Rev. Vaccines."},{"key":"10.1016\/j.imlet.2025.107123_bib0009","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1056\/NEJMoa2101765","article-title":"BNT162b2 mRNA covid-19 vaccine in a nationwide mass vaccination setting","volume":"384","author":"Dagan","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.imlet.2025.107123_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2022.101783","article-title":"Risk of autoimmune diseases in patients with COVID-19: a retrospective cohort study","volume":"56","author":"Chang","year":"2023","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.imlet.2025.107123_bib0011","article-title":"A case of TAFRO syndrome developed after COVID-19 vaccination","volume":"2023","author":"Hirose","year":"2023","journal-title":"Case Rep. Nephrol."},{"key":"10.1016\/j.imlet.2025.107123_bib0012","first-page":"10","article-title":"Idiopathic multicentric Castleman disease occurring shortly after mRNA SARS-CoV-2 vaccine","author":"Hoffmann","year":"2022","journal-title":"Vaccines. (Basel)"},{"key":"10.1016\/j.imlet.2025.107123_bib0013","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s12882-024-03630-x","article-title":"A case of TAFRO syndrome after vaccination, successfully treated with cyclosporine","volume":"25","author":"Mimura","year":"2024","journal-title":"BMC. Nephrol."},{"key":"10.1016\/j.imlet.2025.107123_bib0014","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.jiac.2022.04.005","article-title":"TAFRO syndrome with a fatal clinical course following BNT162b2 mRNA (Pfizer-BioNTech) COVID-19 vaccination: a case report","volume":"28","author":"Yamada","year":"2022","journal-title":"J. Infect. ChemOther"},{"key":"10.1016\/j.imlet.2025.107123_bib0015","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1093\/mrcr\/rxae045","article-title":"Idiopathic multicentric Castleman disease-TAFRO after COVID-19: a case report","volume":"9","author":"Shiina","year":"2025","journal-title":"Mod. Rheumatol. Case Rep."},{"key":"10.1016\/j.imlet.2025.107123_bib0016","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s12185-023-03589-9","article-title":"Severe systemic inflammation mimicking TAFRO syndrome following COVID-19","volume":"118","author":"Tane","year":"2023","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.imlet.2025.107123_bib0017","article-title":"Thrombocytopenia, anasarca, fever, reticulum fibrosis, and organomegaly syndrome triggered by vaccination against SARS-CoV-2 messenger RNA vaccine","volume":"9","author":"Aizawa","year":"2025","journal-title":"Mod. Rheumatol. Case Rep."},{"key":"10.1016\/j.imlet.2025.107123_bib0018","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s12185-019-02780-1","article-title":"2019 Updated diagnostic criteria and disease severity classification for TAFRO syndrome","volume":"111","author":"Masaki","year":"2020","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.imlet.2025.107123_bib0019","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1182\/blood-2016-10-746933","article-title":"International, evidence-based consensus diagnostic criteria for HHV-8-negative\/idiopathic multicentric Castleman disease","volume":"129","author":"Fajgenbaum","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.imlet.2025.107123_bib0020","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00277-022-04762-6","article-title":"Castleman disease and TAFRO syndrome","volume":"101","author":"Masaki","year":"2022","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.imlet.2025.107123_bib0021","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231810301","article-title":"Idiopathic plasmacytic lymphadenopathy forms an independent subtype of Idiopathic multicentric Castleman disease","volume":"23","author":"Nishikori","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.imlet.2025.107123_bib0022","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1080\/14397595.2017.1366093","article-title":"Tentative diagnostic criteria and disease severity classification for Castleman disease: a report of the research group on Castleman disease in Japan","volume":"28","author":"Fujimoto","year":"2018","journal-title":"Mod. Rheumatol."}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247825001567?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247825001567?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T22:36:12Z","timestamp":1785969372000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247825001567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":22,"alternative-id":["S0165247825001567"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2025.107123","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential link between COVID-19 infection\/vaccination and the onsets of TAFRO syndrome and idiopathic multicentric castleman disease","name":"articletitle","label":"Article Title"},{"value":"Immunology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imlet.2025.107123","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V. on behalf of European Federation of Immunological Societies.","name":"copyright","label":"Copyright"}],"article-number":"107123"}}