{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T02:18:45Z","timestamp":1783045125263,"version":"3.54.6"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010877","name":"Science, Technology and Innovation Commission of Shenzhen Municipality","doi-asserted-by":"publisher","award":["JCYJ20240813150301002"],"award-info":[{"award-number":["JCYJ20240813150301002"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010877","name":"Science, Technology and Innovation Commission of Shenzhen Municipality","doi-asserted-by":"publisher","award":["JCYJ20250604143719026"],"award-info":[{"award-number":["JCYJ20250604143719026"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010877","name":"Science, Technology and Innovation Commission of Shenzhen Municipality","doi-asserted-by":"publisher","award":["JCYJ20210324123003009"],"award-info":[{"award-number":["JCYJ20210324123003009"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010877","name":"Science, Technology and Innovation Commission of Shenzhen Municipality","doi-asserted-by":"publisher","award":["JCYJ20220530144814032"],"award-info":[{"award-number":["JCYJ20220530144814032"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82202579"],"award-info":[{"award-number":["82202579"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82372312"],"award-info":[{"award-number":["82372312"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunology Letters"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.imlet.2026.107181","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:04:26Z","timestamp":1777590266000},"page":"107181","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Upregulated Macrophage-Inducible C-Type Lectin on Intermediate Monocytes Facilitates T Helper 17 Cell Differentiation in Systemic Lupus Erythematosus"],"prefix":"10.1016","volume":"280","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0651-9095","authenticated-orcid":false,"given":"Shuping","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Sui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhizhuang Joe","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihua","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.imlet.2026.107181_bib0001","doi-asserted-by":"crossref","DOI":"10.1038\/srep15049","article-title":"Induction of Mincle by Helicobacter pylori and consequent anti-inflammatory signaling denote a bacterial survival strategy","volume":"5","author":"Devi","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.imlet.2026.107181_bib0002","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.3389\/fimmu.2017.01662","article-title":"Sensing lipids with Mincle: structure and function","volume":"8","author":"Williams","year":"2017","journal-title":"Front. Immunol."},{"issue":"29","key":"10.1016\/j.imlet.2026.107181_bib0003","doi-asserted-by":"crossref","first-page":"18656","DOI":"10.1074\/jbc.273.29.18656","article-title":"Cloning of a novel C-type lectin expressed by murine macrophages","volume":"273","author":"Balch","year":"1998","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.imlet.2026.107181_bib0004","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/intimm\/dxy028","article-title":"20 years of a versatile sensor of insults","volume":"30","author":"X","year":"2018","journal-title":"Int. Immunol."},{"issue":"7","key":"10.1016\/j.imlet.2026.107181_bib0005","doi-asserted-by":"crossref","first-page":"3148","DOI":"10.4049\/jimmunol.1502355","article-title":"Mincle activation and the syk\/Card9 signaling axis are Central to the development of autoimmune disease of the eye","volume":"196","author":"Lee","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.imlet.2026.107181_bib0006","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.phymed.2018.09.210","article-title":"Curcumin relieved cisplatin-induced kidney inflammation through inhibiting mincle-maintained M1 macrophage phenotype","volume":"52","author":"Tan","year":"2019","journal-title":"Phytomedicine"},{"issue":"2","key":"10.1016\/j.imlet.2026.107181_bib0007","doi-asserted-by":"crossref","DOI":"10.1038\/emm.2017.256","article-title":"Integrin CD11b negatively regulates Mincle-induced signaling via the Lyn-SIRPalpha-SHP1 complex","volume":"50","author":"Zhang","year":"2018","journal-title":"Exp. Mol. Med."},{"issue":"1","key":"10.1016\/j.imlet.2026.107181_bib0008","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1038\/s41598-018-37318-8","article-title":"Essential roles of C-type lectin Mincle in induction of neuropathic pain in mice","volume":"9","author":"Ishikawa","year":"2019","journal-title":"Sci. Rep."},{"issue":"9","key":"10.1016\/j.imlet.2026.107181_bib0009","doi-asserted-by":"crossref","first-page":"5039","DOI":"10.4049\/jimmunol.163.9.5039","article-title":"A novel LPS-inducible C-type lectin is a transcriptional target of NF-IL6 in macrophages","volume":"163","author":"Matsumoto","year":"1999","journal-title":"J. Immunol."},{"issue":"11","key":"10.1016\/j.imlet.2026.107181_bib0010","doi-asserted-by":"crossref","first-page":"7404","DOI":"10.4049\/jimmunol.180.11.7404","article-title":"The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans","volume":"180","author":"Wells","year":"2008","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.imlet.2026.107181_bib0011","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/icb.2012.24","article-title":"Mincle polarizes human monocyte and neutrophil responses to Candida albicans","volume":"90","author":"Vijayan","year":"2012","journal-title":"Immunol. Cell Biol."},{"issue":"7","key":"10.1016\/j.imlet.2026.107181_bib0012","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/s00251-004-0714-x","article-title":"Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex","volume":"56","author":"Flornes","year":"2004","journal-title":"Immunogenetics"},{"issue":"1","key":"10.1016\/j.imlet.2026.107181_bib0013","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1128\/IAI.02500-14","article-title":"Macrophage-inducible C-type lectin mincle-expressing dendritic cells contribute to control of splenic mycobacterium bovis BCG infection in mice","volume":"83","author":"Behler","year":"2015","journal-title":"Infect. Immun."},{"issue":"10","key":"10.1016\/j.imlet.2026.107181_bib0014","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1038\/ni.1651","article-title":"Mincle is an ITAM-coupled activating receptor that senses damaged cells","volume":"9","author":"Yamasaki","year":"2008","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.imlet.2026.107181_bib0015","doi-asserted-by":"crossref","first-page":"861","DOI":"10.3389\/fimmu.2017.00861","article-title":"Macrophage inducible C-type lectin As a multifunctional player in immunity","volume":"8","author":"Patin","year":"2017","journal-title":"Front. Immunol."},{"issue":"14","key":"10.1016\/j.imlet.2026.107181_bib0016","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1161\/CIRCULATIONAHA.116.022668","article-title":"Necrotic cell sensor Clec4e promotes a proatherogenic macrophage phenotype through activation of the unfolded protein response","volume":"134","author":"Clement","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.imlet.2026.107181_bib0017","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1146\/annurev.immunol.021908.132557","article-title":"Blood monocytes: development, heterogeneity, and relationship with dendritic cells","volume":"27","author":"Auffray","year":"2009","journal-title":"Annu. Rev. Immunol."},{"issue":"11","key":"10.1016\/j.imlet.2026.107181_bib0018","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/nri3070","article-title":"Monocyte recruitment during infection and inflammation","volume":"11","author":"Shi","year":"2011","journal-title":"Nat. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.imlet.2026.107181_bib0019","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1182\/blood-2010-12-326355","article-title":"Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets","volume":"118","author":"Wong","year":"2011","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.imlet.2026.107181_bib0020","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/ni.3777","article-title":"The monogenic autoinflammatory diseases define new pathways in human innate immunity and inflammation","volume":"18","author":"Manthiram","year":"2017","journal-title":"Nat. Immunol."},{"issue":"1","key":"10.1016\/j.imlet.2026.107181_bib0021","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s12967-023-03943-9","article-title":"Xing S. Bioinformatics analyses of combined databases identify shared differentially expressed genes in cancer and autoimmune disease","volume":"21","author":"Sui","year":"2023","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.imlet.2026.107181_bib0022","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s13059-016-0948-6","article-title":"Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations","volume":"17","author":"Walsh","year":"2016","journal-title":"Genome Biol."},{"issue":"12","key":"10.1016\/j.imlet.2026.107181_bib0023","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1038\/ng.3434","article-title":"Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus","volume":"47","author":"Bentham","year":"2015","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.imlet.2026.107181_bib0024","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1172\/JCI125116","article-title":"Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis","volume":"129","author":"Kuriakose","year":"2019","journal-title":"J. Clin. Invest."},{"issue":"8","key":"10.1016\/j.imlet.2026.107181_bib0025","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1038\/nrrheum.2016.91","article-title":"Macrophage heterogeneity in the context of rheumatoid arthritis","volume":"12","author":"Udalova","year":"2016","journal-title":"Nat. Rev. Rheumatol."},{"issue":"9","key":"10.1016\/j.imlet.2026.107181_bib0026","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/s41419-021-04052-5","article-title":"C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1(+) M-MDSCs in relieving lupus-like symptoms","volume":"12","author":"Li","year":"2021","journal-title":"Cell Death. Dis."},{"key":"10.1016\/j.imlet.2026.107181_bib0027","doi-asserted-by":"crossref","first-page":"512","DOI":"10.3389\/fimmu.2016.00512","article-title":"CD16(+) Monocyte subset was enriched and functionally exacerbated in driving T-cell activation and B-cell response in systemic Lupus erythematosus","volume":"7","author":"Zhu","year":"2016","journal-title":"Front. Immunol."},{"key":"10.1016\/j.imlet.2026.107181_bib0028","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.coi.2014.12.002","article-title":"C-type lectins in immunity: recent developments","volume":"32","author":"IM","year":"2015","journal-title":"Curr. Opin. Immunol."},{"issue":"5","key":"10.1016\/j.imlet.2026.107181_bib0029","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.4049\/jimmunol.1500102","article-title":"Contribution of MINCLE-SYK signaling to activation of primary Human APCs by mycobacterial cord factor and the novel adjuvant TDB","volume":"195","author":"Ostrop","year":"2015","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.imlet.2026.107181_bib0030","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.4049\/jimmunol.0904013","article-title":"Cutting edge: mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate","volume":"184","author":"Schoenen","year":"2010","journal-title":"J. Immunol."},{"issue":"24","key":"10.1016\/j.imlet.2026.107181_bib0031","doi-asserted-by":"crossref","first-page":"6179","DOI":"10.1111\/j.1742-4658.2005.05031.x","article-title":"The C-type lectin-like domain superfamily","volume":"272","author":"Zelensky","year":"2005","journal-title":"FEBS. J."},{"issue":"Suppl 2","key":"10.1016\/j.imlet.2026.107181_bib0032","article-title":"Neutrophil phenotypes in health and disease","volume":"48","author":"Hellebrekers","year":"2018","journal-title":"Eur. J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.imlet.2026.107181_bib0033","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40348-018-0083-4","article-title":"Anti-inflammatory monocytes-interplay of innate and adaptive immunity","volume":"5","author":"Varga","year":"2018","journal-title":"Mol. Cell Pediatr."},{"key":"10.1016\/j.imlet.2026.107181_bib0034","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.3389\/fimmu.2020.01070","article-title":"Human monocyte subset distinctions and function: insights from gene expression analysis","volume":"11","author":"Cormican","year":"2020","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.imlet.2026.107181_bib0035","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/hep.26016","article-title":"Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics","volume":"57","author":"Liaskou","year":"2013","journal-title":"Hepatology"},{"issue":"12","key":"10.1016\/j.imlet.2026.107181_bib0036","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1042\/CS20170009","article-title":"Monocyte subtypes and the CCR2 chemokine receptor in cardiovascular disease","volume":"131","author":"Fran\u00e7a","year":"2017","journal-title":"Clin. Sci. (Lond.)"},{"issue":"4","key":"10.1016\/j.imlet.2026.107181_bib0037","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002817","article-title":"Circulating CD14brightCD16+ 'intermediate' monocytes exhibit enhanced parasite pattern recognition in human helminth infection","volume":"8","author":"Turner","year":"2014","journal-title":"PLoS. Negl. Trop. Dis."},{"issue":"11","key":"10.1016\/j.imlet.2026.107181_bib0038","doi-asserted-by":"crossref","first-page":"5150","DOI":"10.4049\/jimmunol.1402409","article-title":"CD14++CD16+ Monocytes are enriched by glucocorticoid treatment and are functionally attenuated in driving effector T cell responses","volume":"194","author":"Liu","year":"2015","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.imlet.2026.107181_bib0039","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12865-019-0319-7","article-title":"Foxp3(+)Helios(+) regulatory T cells are associated with monocyte subsets and their PD-1 expression during acute HIV-1 infection","volume":"20","author":"Liu","year":"2019","journal-title":"BMC. Immunol."},{"issue":"5","key":"10.1016\/j.imlet.2026.107181_bib0040","doi-asserted-by":"crossref","first-page":"749","DOI":"10.3899\/jrheum.140630","article-title":"Surface APRIL is elevated on myeloid cells and is associated with disease activity in patients with rheumatoid arthritis","volume":"42","author":"Weldon","year":"2015","journal-title":"J. Rheumatol."},{"issue":"1","key":"10.1016\/j.imlet.2026.107181_bib0041","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1053\/j.ajkd.2007.04.012","article-title":"Elevated levels of fractalkine expression and accumulation of CD16+ monocytes in glomeruli of active lupus nephritis","volume":"50","author":"Yoshimoto","year":"2007","journal-title":"Am. J. Kidney Dis."},{"issue":"10188","key":"10.1016\/j.imlet.2026.107181_bib0042","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1016\/S0140-6736(19)30237-5","article-title":"Management strategies and future directions for systemic lupus erythematosus in adults","volume":"393","author":"Durcan","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.imlet.2026.107181_bib0043","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.3389\/fimmu.2020.01572","article-title":"Targeting the protective arm of the Renin-Angiotensin system to reduce systemic lupus erythematosus related pathologies in MRL-lpr mice","volume":"11","author":"Soto","year":"2020","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.imlet.2026.107181_bib0044","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0034080","article-title":"Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of toll like receptors and the Clec4e","volume":"7","author":"Thiyagarajan","year":"2012","journal-title":"PLoS. One"},{"issue":"17","key":"10.1016\/j.imlet.2026.107181_bib0045","first-page":"3115","article-title":"Macrophage-inducible C-type lectin is associated with anti-cyclic citrullinated peptide antibodies-positive rheumatoid arthritis in men","volume":"125","author":"Wu","year":"2012","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.imlet.2026.107181_bib0046","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.589200","article-title":"C-reactive protein suppresses the Th17 response indirectly by attenuating the antigen presentation ability of monocyte derived dendritic cells in experimental autoimmune encephalomyelitis","volume":"12","author":"Shen","year":"2021","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.imlet.2026.107181_bib0047","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1093\/rheumatology\/keaa625","article-title":"Monocytic MDSCs skew Th17 cells toward a pro-osteoclastogenic phenotype and potentiate bone erosion in rheumatoid arthritis","volume":"60","author":"Chen","year":"2021","journal-title":"Rheumatology"},{"issue":"8","key":"10.1016\/j.imlet.2026.107181_bib0048","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1002\/cmdc.202000775","article-title":"Design of trehalose-based amide\/sulfonamide C-type lectin receptor signaling compounds","volume":"16","author":"Rasheed","year":"2021","journal-title":"ChemMedChem"},{"issue":"2","key":"10.1016\/j.imlet.2026.107181_bib0049","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.immuni.2018.12.020","article-title":"Microbiota sensing by Mincle-Syk axis in dendritic cells regulates interleukin-17 and -22 production and promotes intestinal barrier integrity","volume":"50","author":"Mart\u00ednez-L\u00f3pez","year":"2019","journal-title":"Immunity"},{"issue":"11","key":"10.1016\/j.imlet.2026.107181_bib0050","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1093\/intimm\/dxz036","article-title":"Monocyte subsets involved in the development of systemic lupus erythematosus and rheumatoid arthritis","volume":"31","author":"Hirose","year":"2019","journal-title":"Int. Immunol."},{"issue":"4","key":"10.1016\/j.imlet.2026.107181_bib0051","first-page":"469","article-title":"Peripheral classic and intermediate monocyte subsets as immune biomarkers of systemic Lupus Erythematosus Disease activity","volume":"56","author":"Oehadian","year":"2024","journal-title":"Acta Med. Indones."},{"issue":"1","key":"10.1016\/j.imlet.2026.107181_bib0052","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s10067-023-06832-0","article-title":"Utility of peripheral blood monocyte subsets, circulating immune complexes and serum cytokines in assessment of SLE activity: an observational, cross-sectional study","volume":"43","author":"Jha","year":"2024","journal-title":"Clin. Rheumatol."},{"issue":"7","key":"10.1016\/j.imlet.2026.107181_bib0053","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1136\/ard-2023-225433","article-title":"Disease activity drives divergent epigenetic and transcriptomic reprogramming of monocyte subpopulations in systemic lupus erythematosus","volume":"83","author":"Ferret\u00e9-Bonastre","year":"2024","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.imlet.2026.107181_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2023.109765","article-title":"Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus","volume":"255","author":"Stergioti","year":"2023","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.imlet.2026.107181_bib0055","article-title":"Transcobalamin 2 orchestrates monocyte proliferation and TLR4-driven inflammation in systemic lupus erythematosus via folate one-carbon metabolism","volume":"15","author":"Liu","year":"2024","journal-title":"Front. Immunol."},{"issue":"15","key":"10.1016\/j.imlet.2026.107181_bib0056","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25158278","article-title":"Peripheral blood mononuclear cells and serum cytokines in patients with Lupus nephritis after COVID-19","volume":"25","author":"Lisowska","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.imlet.2026.107181_bib0057","article-title":"CLEC4E as a molecular biomarker in systemic lupus erythematosus: integrating bioinformatics and clinical data to assess its prognostic value","volume":"16","author":"Ma","year":"2025","journal-title":"Front. Immunol."}],"container-title":["Immunology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247826000544?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165247826000544?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:48:49Z","timestamp":1783043329000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165247826000544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":57,"alternative-id":["S0165247826000544"],"URL":"https:\/\/doi.org\/10.1016\/j.imlet.2026.107181","relation":{},"ISSN":["0165-2478"],"issn-type":[{"value":"0165-2478","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Upregulated Macrophage-Inducible C-Type Lectin on Intermediate Monocytes Facilitates T Helper 17 Cell Differentiation in Systemic Lupus Erythematosus","name":"articletitle","label":"Article Title"},{"value":"Immunology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imlet.2026.107181","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 European Federation of Immunological Societies. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107181"}}