{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T01:36:01Z","timestamp":1791509761617,"version":"4.3.4"},"reference-count":45,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,3]],"date-time":"2013-10-03T00:00:00Z","timestamp":1380758400000},"content-version":"vor","delay-in-days":397,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.immuni.2012.05.029","type":"journal-article","created":{"date-parts":[[2012,8,30]],"date-time":"2012-08-30T12:19:49Z","timestamp":1346329189000},"page":"549-562","source":"Crossref","is-referenced-by-count":261,"title":["Inflammatory Monocytes Activate Memory CD8+ T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion"],"prefix":"10.1016","volume":"37","author":[{"given":"Sa\u00efdi\u00a0M'Homa","family":"Soudja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u00a0L.","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien\u00a0C.","family":"Marie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gr\u00e9goire","family":"Lauvau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.immuni.2012.05.029_bib1","doi-asserted-by":"crossref","first-page":"e11524","DOI":"10.1371\/journal.pone.0011524","article-title":"Visualizing early splenic memory CD8+ T\u00a0cells reactivation against intracellular bacteria in the mouse","volume":"5","author":"Baj\u00e9noff","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.immuni.2012.05.029_bib2","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/nature05762","article-title":"Herpesvirus latency confers symbiotic protection from bacterial infection","volume":"447","author":"Barton","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2012.05.029_bib3","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1084\/jem.20031051","article-title":"Memory CD8+ T\u00a0cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen","volume":"198","author":"Berg","year":"2003","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2012.05.029_bib4","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.4049\/jimmunol.1004210","article-title":"Cutting Edge: A dual role for type I IFNs during polyinosinic-polycytidylic acid-induced NK cell activation","volume":"187","author":"Beuneu","year":"2011","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib5","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1084\/jem.20041389","article-title":"Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T\u00a0cell homeostasis","volume":"200","author":"Burkett","year":"2004","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2012.05.029_bib6","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.4049\/jimmunol.181.3.1627","article-title":"Cutting edge: Priming of NK cells by IL-18","volume":"181","author":"Chaix","year":"2008","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib7","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/nri3087","article-title":"Studying the mononuclear phagocyte system in the molecular age","volume":"11","author":"Chow","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib8","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.4049\/jimmunol.167.4.2004","article-title":"The source of early IFN-gamma that plays a role in Th1 priming","volume":"167","author":"Das","year":"2001","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib9","doi-asserted-by":"crossref","first-page":"e6510","DOI":"10.1371\/journal.pone.0006510","article-title":"Malarial hemozoin is a Nalp3 inflammasome activating danger signal","volume":"4","author":"Dostert","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.immuni.2012.05.029_bib10","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.immuni.2011.06.012","article-title":"CD8\u03b1(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes","volume":"35","author":"Edelson","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib11","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/nature07815","article-title":"IFNalpha activates dormant haematopoietic stem cells in\u00a0vivo","volume":"458","author":"Essers","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2012.05.029_bib12","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1074-7613(03)00174-2","article-title":"Blood monocytes consist of two principal subsets with distinct migratory properties","volume":"19","author":"Geissmann","year":"2003","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib13","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1126\/science.1178331","article-title":"Development of monocytes, macrophages, and dendritic cells","volume":"327","author":"Geissmann","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.immuni.2012.05.029_bib14","doi-asserted-by":"crossref","first-page":"7859","DOI":"10.4049\/jimmunol.180.12.7859","article-title":"Dependency of caspase-1 activation induced in macrophages by\u00a0Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm","volume":"180","author":"Hara","year":"2008","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib15","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.chom.2009.10.007","article-title":"Inflammatory monocytes facilitate adaptive CD4 T\u00a0cell responses during respiratory fungal infection","volume":"6","author":"Hohl","year":"2009","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.immuni.2012.05.029_bib16","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1038\/ni1268","article-title":"Effector and memory CD8+ T\u00a0cell fate coupled by T-bet and eomesodermin","volume":"6","author":"Intlekofer","year":"2005","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib17","doi-asserted-by":"crossref","first-page":"e2404","DOI":"10.1371\/journal.pone.0002404","article-title":"An IFN-gamma-IL-18 signaling loop accelerates memory CD8+ T\u00a0cell proliferation","volume":"3","author":"Iwai","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1016\/j.immuni.2012.05.029_bib18","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1126\/science.1183021","article-title":"Regulation of adaptive immunity by the innate immune system","volume":"327","author":"Iwasaki","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.immuni.2012.05.029_bib19","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S1074-7613(02)00365-5","article-title":"In\u00a0vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T\u00a0cells by exogenous cell-associated antigens","volume":"17","author":"Jung","year":"2002","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib20","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.immuni.2009.11.010","article-title":"Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T\u00a0cells favors terminal-effector differentiation in\u00a0vivo","volume":"32","author":"Kalia","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib21","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.4049\/jimmunol.170.5.2399","article-title":"Memory CD8+ T\u00a0cells provide an early source of IFN-gamma","volume":"170","author":"Kambayashi","year":"2003","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib22","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.immuni.2010.06.016","article-title":"Type I interferons regulate cytolytic activity of memory CD8(+) T\u00a0cells in the lung airways during respiratory virus challenge","volume":"33","author":"Kohlmeier","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib23","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1126\/science.7535475","article-title":"Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme","volume":"267","author":"Kuida","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.immuni.2012.05.029_bib24","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/ni.2195","article-title":"NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8\u207a T\u00a0cells","volume":"13","author":"Kupz","year":"2012","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib25","doi-asserted-by":"crossref","first-page":"6192","DOI":"10.1073\/pnas.092675799","article-title":"IL-15 mimics T\u00a0cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T\u00a0cells","volume":"99","author":"Liu","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2012.05.029_bib26","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.immuni.2007.03.006","article-title":"Dendritic cells prime natural killer cells by trans-presenting interleukin 15","volume":"26","author":"Lucas","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib27","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1172\/JCI31990","article-title":"Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigens","volume":"117","author":"Miyake","year":"2007","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2012.05.029_bib28","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1084\/jem.20071913","article-title":"IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation","volume":"205","author":"Mortier","year":"2008","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2012.05.029_bib29","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.immuni.2009.09.017","article-title":"Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T\u00a0cell subsets","volume":"31","author":"Mortier","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib30","doi-asserted-by":"crossref","first-page":"e1002457","DOI":"10.1371\/journal.ppat.1002457","article-title":"Inflammatory monocytes and neutrophils are licensed to kill during memory responses in\u00a0vivo","volume":"7","author":"Narni-Mancinelli","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.immuni.2012.05.029_bib31","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.immuni.2006.07.017","article-title":"CD8alpha+ dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen","volume":"25","author":"Neuenhahn","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib32","doi-asserted-by":"crossref","first-page":"4279","DOI":"10.4049\/jimmunol.169.8.4279","article-title":"Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection","volume":"169","author":"Nguyen","year":"2002","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib33","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1084\/jem.20061297","article-title":"Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in\u00a0vivo","volume":"203","author":"Ohteki","year":"2006","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2012.05.029_bib34","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.immuni.2009.11.012","article-title":"Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T\u00a0cells","volume":"32","author":"Pipkin","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib35","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1365-2249.2005.02868.x","article-title":"Histological analysis of CD11c-DTR\/GFP mice after in\u00a0vivo depletion of dendritic cells","volume":"141","author":"Probst","year":"2005","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib36","doi-asserted-by":"crossref","first-page":"6537","DOI":"10.4049\/jimmunol.173.11.6537","article-title":"Cutting edge: transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15R alpha by the same cells","volume":"173","author":"Sandau","year":"2004","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib37","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/ni1309","article-title":"Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2","volume":"7","author":"Serbina","year":"2006","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib38","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S1074-7613(03)00171-7","article-title":"TNF\/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection","volume":"19","author":"Serbina","year":"2003","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib39","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/nri3070","article-title":"Monocyte recruitment during infection and inflammation","volume":"11","author":"Shi","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib40","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1128\/IAI.01269-07","article-title":"Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in\u00a0vitro: a novel function of pneumolysin in caspase-1 activation","volume":"76","author":"Shoma","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.immuni.2012.05.029_bib41","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/jlb.45.2.97","article-title":"Macrophage subset repopulation in the spleen: differential kinetics after liposome-mediated elimination","volume":"45","author":"van Rooijen","year":"1989","journal-title":"J.\u00a0Leukoc. Biol."},{"key":"10.1016\/j.immuni.2012.05.029_bib42","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1002\/eji.201040730","article-title":"Secondary CD8+ T-cell responses are controlled by systemic inflammation","volume":"41","author":"Wirth","year":"2011","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib43","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.4049\/jimmunol.174.6.3590","article-title":"A novel role of IL-15 in early activation of memory CD8+ CTL after reinfection","volume":"174","author":"Yajima","year":"2005","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2012.05.029_bib44","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.immuni.2005.03.005","article-title":"Dendritic cells maximize the memory CD8 T\u00a0cell response to infection","volume":"22","author":"Zammit","year":"2005","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2012.05.029_bib45","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S1074-7613(00)80564-6","article-title":"Potent and selective stimulation of memory-phenotype CD8+ T\u00a0cells in\u00a0vivo by IL-15","volume":"8","author":"Zhang","year":"1998","journal-title":"Immunity"}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761312003688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761312003688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T03:16:29Z","timestamp":1562123789000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761312003688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S1074761312003688"],"URL":"https:\/\/doi.org\/10.1016\/j.immuni.2012.05.029","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717955601.793464312","asserted-by":"object"}]},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}