{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:32:56Z","timestamp":1791894776861,"version":"4.3.4"},"reference-count":101,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,20]],"date-time":"2016-10-20T00:00:00Z","timestamp":1476921600000},"content-version":"vor","delay-in-days":385,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.immuni.2015.09.013","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T12:00:19Z","timestamp":1445342419000},"page":"634-645","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":333,"title":["Natural Killer Cell Memory"],"prefix":"10.1016","volume":"43","author":[{"given":"Timothy\u00a0E.","family":"O\u2019Sullivan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph\u00a0C.","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis\u00a0L.","family":"Lanier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.immuni.2015.09.013_bib1","doi-asserted-by":"crossref","first-page":"e32821","DOI":"10.1371\/journal.pone.0032821","article-title":"Genital HSV-2 infection induces short-term NK cell memory","volume":"7","author":"Abdul-Careem","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.immuni.2015.09.013_bib2","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1126\/science.1070884","article-title":"Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors","volume":"296","author":"Arase","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.immuni.2015.09.013_bib3","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/nature14189","article-title":"The biology of innate lymphoid cells","volume":"517","author":"Artis","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2015.09.013_bib4","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/ni.2876","article-title":"The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection","volume":"15","author":"Beaulieu","year":"2014","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib5","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/eji.201141826","article-title":"CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients","volume":"42","author":"B\u00e9ziat","year":"2012","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib6","doi-asserted-by":"crossref","first-page":"2678","DOI":"10.1182\/blood-2012-10-459545","article-title":"NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs","volume":"121","author":"B\u00e9ziat","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib7","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s00430-015-0412-3","article-title":"Immunoregulatory cytokine networks: 60 years of learning from murine cytomegalovirus","volume":"204","author":"Biron","year":"2015","journal-title":"Med. Microbiol. Immunol. (Berl.)"},{"key":"10.1016\/j.immuni.2015.09.013_bib8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1084\/jem.20100762","article-title":"Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus","volume":"208","author":"Bj\u00f6rkstr\u00f6m","year":"2011","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib9","doi-asserted-by":"crossref","first-page":"e27664","DOI":"10.1371\/journal.pone.0027664","article-title":"Characterization of natural killer cell phenotype and\u00a0function during recurrent human HSV-2 infection","volume":"6","author":"Bj\u00f6rkstr\u00f6m","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.immuni.2015.09.013_bib10","doi-asserted-by":"crossref","first-page":"3638","DOI":"10.4049\/jimmunol.0803580","article-title":"Decreased NK cell frequency and function is associated with increased risk of KIR3DL allele polymorphism in simian immunodeficiency virus-infected rhesus macaques with high viral loads","volume":"182","author":"Bostik","year":"2009","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib11","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1007\/s00018-012-0968-7","article-title":"Homeostatic maintenance of T\u00a0cells and natural killer cells","volume":"69","author":"Boyman","year":"2012","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.immuni.2015.09.013_bib12","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1126\/science.1060042","article-title":"Vital involvement of a natural killer cell activation receptor in resistance to viral infection","volume":"292","author":"Brown","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.immuni.2015.09.013_bib13","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/QAD.0b013e3283328d1f","article-title":"Chronic HIV-1 viremia reverses NKG2A\/NKG2C ratio on natural killer cells in patients with human cytomegalovirus co-infection","volume":"24","author":"Brunetta","year":"2010","journal-title":"AIDS"},{"key":"10.1016\/j.immuni.2015.09.013_bib14","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/nm.3521","article-title":"Essential role for autophagy in the maintenance of immunological memory against influenza infection","volume":"20","author":"Chen","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib15","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1073\/pnas.0813192106","article-title":"Cytokine-induced memory-like natural killer cells","volume":"106","author":"Cooper","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2015.09.013_bib16","doi-asserted-by":"crossref","first-page":"4487","DOI":"10.4049\/jimmunol.1303469","article-title":"Cutting edge: Salivary gland NK cells develop independently of Nfil3 in steady-state","volume":"192","author":"Cortez","year":"2014","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib17","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1084\/jem.194.1.29","article-title":"Murine cytomegalovirus is regulated by a discrete subset of natural killer cells reactive with monoclonal antibody to Ly49H","volume":"194","author":"Daniels","year":"2001","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib18","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1084\/jem.20131560","article-title":"T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow","volume":"211","author":"Daussy","year":"2014","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib19","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1182\/blood-2011-08-372003","article-title":"Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus?","volume":"119","author":"Della Chiesa","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib20","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1146\/annurev.immunol.24.021605.090700","article-title":"Natural killer cell developmental pathways: a question of balance","volume":"24","author":"Di Santo","year":"2006","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib21","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1038\/ni714","article-title":"Specific and nonspecific NK cell activation during virus infection","volume":"2","author":"Dokun","year":"2001","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib22","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.4049\/jimmunol.178.5.2688","article-title":"NKp46 and\u00a0NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to influenza infection","volume":"178","author":"Draghi","year":"2007","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib23","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1084\/jem.20130417","article-title":"Nfil3-independent lineage maintenance and antiviral response of natural killer cells","volume":"210","author":"Firth","year":"2013","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib24","doi-asserted-by":"crossref","first-page":"5082","DOI":"10.4049\/jimmunol.1201964","article-title":"Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in\u00a0vivo in response to recipient CMV antigen","volume":"189","author":"Foley","year":"2012","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib25","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1182\/blood-2011-10-386995","article-title":"Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function","volume":"119","author":"Foley","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib26","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/ni1322","article-title":"Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1","volume":"7","author":"Gazit","year":"2006","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib27","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1128\/JVI.74.4.1648-1657.2000","article-title":"Cytokine expression, natural killer cell activation, and phenotypic changes in lymphoid cells from rhesus macaques during acute infection with pathogenic simian immunodeficiency virus","volume":"74","author":"Giavedoni","year":"2000","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.immuni.2015.09.013_bib28","doi-asserted-by":"crossref","first-page":"e1002141","DOI":"10.1371\/journal.ppat.1002141","article-title":"Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes","volume":"7","author":"Gillard","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.immuni.2015.09.013_bib29","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1182\/blood-2014-05-576124","article-title":"Rapid NK cell differentiation in a population with near-universal human cytomegalovirus infection is attenuated by NKG2C deletions","volume":"124","author":"Goodier","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib30","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1615\/CritRevImmunol.v21.i5.30","article-title":"Induction and regulation of T-cell priming for contact hypersensitivity","volume":"21","author":"Gorbachev","year":"2001","journal-title":"Crit. Rev. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib31","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.immuni.2011.11.016","article-title":"The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation","volume":"36","author":"Gordon","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2015.09.013_bib32","doi-asserted-by":"crossref","first-page":"3950","DOI":"10.4049\/jimmunol.164.8.3950","article-title":"Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T\u00a0cells","volume":"164","author":"Grayson","year":"2000","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib33","doi-asserted-by":"crossref","first-page":"3664","DOI":"10.1182\/blood-2004-05-2058","article-title":"Imprint of human cytomegalovirus infection on the NK cell receptor repertoire","volume":"104","author":"Gum\u00e1","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib34","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1182\/blood-2005-09-3682","article-title":"Expansion of CD94\/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts","volume":"107","author":"Gum\u00e1","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib35","doi-asserted-by":"crossref","first-page":"4492","DOI":"10.4049\/jimmunol.1303211","article-title":"Cutting edge: NKG2C(hi)CD57+ NK cells respond specifically to acute infection with cytomegalovirus and not Epstein-Barr virus","volume":"192","author":"Hendricks","year":"2014","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib36","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S1074-7613(02)00322-9","article-title":"Activated T\u00a0cell death in\u00a0vivo mediated by proapoptotic bcl-2 family member bim","volume":"16","author":"Hildeman","year":"2002","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2015.09.013_bib37","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1038\/ni1487","article-title":"Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1","volume":"8","author":"Huntington","year":"2007","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib38","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1093\/intimm\/dxs080","article-title":"Identification of human NK cells that are deficient for signaling adaptor FcR\u03b3 and specialized for antibody-dependent immune functions","volume":"24","author":"Hwang","year":"2012","journal-title":"Int. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib39","doi-asserted-by":"crossref","first-page":"864","DOI":"10.4049\/jimmunol.172.2.864","article-title":"Turnover and proliferation of NK cells in steady state and lymphopenic conditions","volume":"172","author":"Jamieson","year":"2004","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib40","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.immuni.2007.08.007","article-title":"Heterogeneity and cell-fate decisions in effector and memory CD8+ T\u00a0cell differentiation during viral infection","volume":"27","author":"Kaech","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2015.09.013_bib41","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.celrep.2014.12.025","article-title":"Homeostatic control of memory cell progenitors in the natural killer cell lineage","volume":"10","author":"Kamimura","year":"2015","journal-title":"Cell Rep."},{"key":"10.1016\/j.immuni.2015.09.013_bib42","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.cell.2014.08.026","article-title":"The RAG recombinase dictates functional heterogeneity and cellular fitness in natural killer cells","volume":"159","author":"Karo","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2015.09.013_bib43","doi-asserted-by":"crossref","first-page":"4754","DOI":"10.4049\/jimmunol.1201742","article-title":"Murine NK cell intrinsic cytokine-induced memory-like responses are maintained following homeostatic proliferation","volume":"190","author":"Keppel","year":"2013","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib44","doi-asserted-by":"crossref","first-page":"5949","DOI":"10.4049\/jimmunol.0802830","article-title":"CD8 T\u00a0cells producing IL-17 and IFN-gamma initiate the innate immune response required for responses to antigen skin challenge","volume":"182","author":"Kish","year":"2009","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib45","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.cell.2014.03.030","article-title":"Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages","volume":"157","author":"Klose","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2015.09.013_bib46","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0092-8674(00)80453-5","article-title":"Identification of clonogenic common lymphoid progenitors in mouse bone marrow","volume":"91","author":"Kondo","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2015.09.013_bib47","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1182\/blood-2008-05-157354","article-title":"Human NK cells can control CMV infection in the absence of T\u00a0cells","volume":"112","author":"Kuijpers","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib48","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1146\/annurev.immunol.23.021704.115526","article-title":"NK cell recognition","volume":"23","author":"Lanier","year":"2005","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib49","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1038\/342803a0","article-title":"Co-association of CD3 zeta with\u00a0a\u00a0receptor (CD16) for IgG Fc on human natural killer cells","volume":"342","author":"Lanier","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2015.09.013_bib50","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.immuni.2015.02.013","article-title":"Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals","volume":"42","author":"Lee","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2015.09.013_bib51","first-page":"676198","article-title":"Natural killer cells in human cancer: from biological functions to clinical applications","volume":"2011","author":"Levy","year":"2011","journal-title":"J.\u00a0Biomed. Biotechnol."},{"key":"10.1016\/j.immuni.2015.09.013_bib52","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1182\/blood-2010-04-282301","article-title":"CD57 defines a\u00a0functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset","volume":"116","author":"Lopez-Verg\u00e8s","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib53","doi-asserted-by":"crossref","first-page":"14725","DOI":"10.1073\/pnas.1110900108","article-title":"Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection","volume":"108","author":"Lopez-Verg\u00e8s","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2015.09.013_bib54","doi-asserted-by":"crossref","first-page":"e1004441","DOI":"10.1371\/journal.ppat.1004441","article-title":"Human cytomegalovirus drives epigenetic imprinting of the IFNG locus in NKG2Chi natural killer cells","volume":"10","author":"Luetke-Eversloh","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.immuni.2015.09.013_bib55","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.4049\/jimmunol.1402001","article-title":"Cutting edge: stage-specific requirement of IL-18 for antiviral NK cell expansion","volume":"194","author":"Madera","year":"2015","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib56","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/imm.12120","article-title":"Natural killer cell-mediated contact sensitivity develops rapidly and depends on interferon-\u03b1, interferon-\u03b3 and interleukin-12","volume":"140","author":"Majewska-Szczepanik","year":"2013","journal-title":"Immunology"},{"key":"10.1016\/j.immuni.2015.09.013_bib57","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1146\/annurev.immunol.22.012703.104554","article-title":"Control of T\u00a0cell viability","volume":"22","author":"Marrack","year":"2004","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib58","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/ng2035","article-title":"Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1","volume":"39","author":"Martin","year":"2007","journal-title":"Nat. Genet."},{"key":"10.1016\/j.immuni.2015.09.013_bib59","doi-asserted-by":"crossref","first-page":"4496","DOI":"10.1128\/JVI.05788-11","article-title":"The human immunodeficiency virus type 1 Nef and Vpu proteins downregulate the natural killer cell-activating ligand PVR","volume":"86","author":"Matusali","year":"2012","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.immuni.2015.09.013_bib60","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1084\/jem.20132459","article-title":"Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection","volume":"211","author":"Min-Oo","year":"2014","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib61","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1084\/jem.20141172","article-title":"Cytomegalovirus generates long-lived antigen-specific NK cells with diminished bystander activation to heterologous infection","volume":"211","author":"Min-Oo","year":"2014","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib62","doi-asserted-by":"crossref","first-page":"3268","DOI":"10.1002\/eji.201343773","article-title":"NKG2C zygosity influences CD94\/NKG2C receptor function and the NK-cell compartment redistribution in response to human cytomegalovirus","volume":"43","author":"Muntasell","year":"2013","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib63","doi-asserted-by":"crossref","first-page":"5948","DOI":"10.4049\/jimmunol.1500424","article-title":"IL-33 receptor ST2 amplifies the expansion of NK cells and enhances host defense during mouse cytomegalovirus infection","volume":"194","author":"Nabekura","year":"2015","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib64","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.immuni.2013.12.011","article-title":"Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection","volume":"40","author":"Nabekura","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2015.09.013_bib65","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1084\/jem.20140798","article-title":"Antigen-specific expansion and differentiation of natural killer cells by alloantigen stimulation","volume":"211","author":"Nabekura","year":"2014","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib66","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1084\/jem.20120944","article-title":"Sustained effector function of IL-12\/15\/18-preactivated NK cells against established tumors","volume":"209","author":"Ni","year":"2012","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib67","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/ni1332","article-title":"T cell- and B cell-independent adaptive immunity mediated by natural killer cells","volume":"7","author":"O\u2019Leary","year":"2006","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib68","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.immuni.2015.07.012","article-title":"BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory","volume":"43","author":"O\u2019Sullivan","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2015.09.013_bib69","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S1286-4579(02)00038-2","article-title":"Human natural killer cell deficiencies and susceptibility to infection","volume":"4","author":"Orange","year":"2002","journal-title":"Microbes Infect."},{"key":"10.1016\/j.immuni.2015.09.013_bib70","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.cell.2010.08.031","article-title":"Natural killer cell education and tolerance","volume":"142","author":"Orr","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2015.09.013_bib71","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.beha.2006.06.004","article-title":"Natural-killer-cell-based treatment in haematopoietic stem-cell transplantation","volume":"19","author":"Passweg","year":"2006","journal-title":"Best Pract. Res. Clin. Haematol."},{"key":"10.1016\/j.immuni.2015.09.013_bib72","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1038\/ni.1953","article-title":"Critical role for the chemokine receptor CXCR6 in NK cell-mediated\u00a0antigen-specific memory of haptens and viruses","volume":"11","author":"Paust","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib73","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1172\/JCI66381","article-title":"Liver-resident NK cells confer adaptive immunity in skin-contact inflammation","volume":"123","author":"Peng","year":"2013","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2015.09.013_bib74","doi-asserted-by":"crossref","first-page":"e1002268","DOI":"10.1371\/journal.ppat.1002268","article-title":"Unconventional repertoire profile is imprinted during acute chikungunya infection for natural killer cells polarization toward cytotoxicity","volume":"7","author":"Petitdemange","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.immuni.2015.09.013_bib75","doi-asserted-by":"crossref","first-page":"16689","DOI":"10.1073\/pnas.0808997105","article-title":"Exploring regulatory mechanisms of CD8+ T\u00a0cell contraction","volume":"105","author":"Prlic","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2015.09.013_bib76","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1084\/jem.20021847","article-title":"In\u00a0vivo survival\u00a0and homeostatic proliferation of natural killer cells","volume":"197","author":"Prlic","year":"2003","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib77","doi-asserted-by":"crossref","first-page":"3","DOI":"10.7554\/eLife.03706","article-title":"Autophagy is a critical regulator of memory CD8(+) T\u00a0cell formation","volume":"3","author":"Puleston","year":"2014","journal-title":"eLife"},{"key":"10.1016\/j.immuni.2015.09.013_bib78","doi-asserted-by":"crossref","first-page":"4887","DOI":"10.1182\/blood-2002-11-3392","article-title":"IL-15 is an essential mediator of peripheral NK-cell homeostasis","volume":"101","author":"Ranson","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib79","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/ni.3227","article-title":"Antigen-specific NK cell memory in rhesus macaques","volume":"16","author":"Reeves","year":"2015","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib80","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/ni.3094","article-title":"Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets","volume":"16","author":"Robinette","year":"2015","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib81","doi-asserted-by":"crossref","first-page":"5305","DOI":"10.1172\/JCI77440","article-title":"IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansion","volume":"124","author":"R\u00f6lle","year":"2014","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2015.09.013_bib82","doi-asserted-by":"crossref","first-page":"4751","DOI":"10.1182\/blood-2012-04-419283","article-title":"Cytokine activation induces human memory-like NK cells","volume":"120","author":"Romee","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2015.09.013_bib83","doi-asserted-by":"crossref","first-page":"13446","DOI":"10.1128\/JVI.02382-13","article-title":"Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells","volume":"87","author":"Saghafian-Hedengren","year":"2013","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.immuni.2015.09.013_bib84","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.immuni.2015.02.008","article-title":"Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function","volume":"42","author":"Schlums","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2015.09.013_bib85","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.chom.2010.10.008","article-title":"Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu","volume":"8","author":"Shah","year":"2010","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.immuni.2015.09.013_bib86","doi-asserted-by":"crossref","first-page":"8826","DOI":"10.1073\/pnas.092258599","article-title":"Recognition of a virus-encoded ligand by a natural killer cell activation receptor","volume":"99","author":"Smith","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2015.09.013_bib87","doi-asserted-by":"crossref","first-page":"e01659","DOI":"10.7554\/eLife.01659","article-title":"Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells","volume":"3","author":"Sojka","year":"2014","journal-title":"eLife"},{"key":"10.1016\/j.immuni.2015.09.013_bib88","doi-asserted-by":"crossref","first-page":"297ra115","DOI":"10.1126\/scitranslmed.aac5722","article-title":"Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility","volume":"7","author":"Strauss-Albee","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib89","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1084\/jem.20100479","article-title":"Homeostatic proliferation generates long-lived natural killer cells that respond against viral infection","volume":"208","author":"Sun","year":"2011","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib90","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nature07665","article-title":"Adaptive immune features of natural killer cells","volume":"457","author":"Sun","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2015.09.013_bib91","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1600-065X.2010.00900.x","article-title":"Immune memory redefined: characterizing the longevity of natural killer cells","volume":"236","author":"Sun","year":"2010","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.immuni.2015.09.013_bib92","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/nri3044","article-title":"NK cell development, homeostasis and function: parallels with CD8+ T\u00a0cells","volume":"11","author":"Sun","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib93","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.4049\/jimmunol.1003035","article-title":"NK cells and immune \u201cmemory\u201d","volume":"186","author":"Sun","year":"2011","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib94","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1084\/jem.20111760","article-title":"Proinflammatory cytokine signaling required for the generation of natural killer cell memory","volume":"209","author":"Sun","year":"2012","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2015.09.013_bib95","doi-asserted-by":"crossref","first-page":"e1003929","DOI":"10.1371\/journal.ppat.1003929","article-title":"In\u00a0vivo administration of a JAK3 inhibitor during acute SIV infection leads to significant increases in viral load during chronic infection","volume":"10","author":"Takahashi","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.immuni.2015.09.013_bib96","doi-asserted-by":"crossref","first-page":"e52027","DOI":"10.1371\/journal.pone.0052027","article-title":"CCR2 defines a distinct population of NK cells and mediates their migration during influenza virus infection in mice","volume":"7","author":"van Helden","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.immuni.2015.09.013_bib97","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1146\/annurev.immunol.25.022106.141548","article-title":"Effector and memory CTL differentiation","volume":"25","author":"Williams","year":"2007","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib98","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1038\/ni.3025","article-title":"Autophagy is essential for effector CD8(+) T\u00a0cell survival and memory formation","volume":"15","author":"Xu","year":"2014","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2015.09.013_bib99","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1101\/sqb.2013.78.020354","article-title":"Tissue-resident natural killer cells","volume":"78","author":"Yokoyama","year":"2013","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"10.1016\/j.immuni.2015.09.013_bib100","doi-asserted-by":"crossref","first-page":"6967","DOI":"10.1073\/pnas.1304410110","article-title":"Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155","volume":"110","author":"Zawislak","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2015.09.013_bib101","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.4049\/jimmunol.1203034","article-title":"Cutting edge: antibody-dependent memory-like NK cells distinguished by FcR\u03b3 deficiency","volume":"190","author":"Zhang","year":"2013","journal-title":"J.\u00a0Immunol."}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761315003982?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761315003982?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,18]],"date-time":"2018-09-18T12:24:50Z","timestamp":1537273490000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761315003982"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":101,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S1074761315003982"],"URL":"https:\/\/doi.org\/10.1016\/j.immuni.2015.09.013","relation":{},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Natural Killer Cell Memory","name":"articletitle","label":"Article Title"},{"value":"Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2015.09.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}