{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:14:07Z","timestamp":1792786447493,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T00:00:00Z","timestamp":1531872000000},"content-version":"vor","delay-in-days":382,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Kyoto University Foundation","id":[{"id":"https:\/\/ror.org\/02kpeqv85","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000069","name":"NIAMS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Nagahama City, Shiga, Japan"},{"name":"Mitsubishi Tanabe Pharma Co.","id":[{"id":"https:\/\/ror.org\/038ehsm73","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Chugai Pharmaceutical Co. Ltd","id":[{"id":"https:\/\/ror.org\/01v743b94","id-type":"ROR","asserted-by":"crossref"}]},{"name":"UCB Japan Co. Ltd"},{"name":"AYUMI Pharmaceutical Co.","id":[{"id":"https:\/\/ror.org\/03gh8db12","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.immuni.2017.06.018","type":"journal-article","created":{"date-parts":[[2017,7,18]],"date-time":"2017-07-18T18:46:29Z","timestamp":1500403589000},"page":"66-79.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"title":["Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis"],"prefix":"10.1016","volume":"47","author":[{"given":"Koichi","family":"Murata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celestia","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chikashi","family":"Terao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenia G.","family":"Giannopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye Ji","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Joon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se-Hwan","family":"Mun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyeon","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoxi","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritoshi","family":"Furu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromu","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Ohmura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichi","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuneyo","family":"Mimori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumihiko","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Hyun","family":"Park-Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel B.","family":"Ivashkiv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.immuni.2017.06.018_bib1","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1016\/j.bbadis.2013.09.014","article-title":"Tuning NF-\u03baB activity: a touch of COMMD proteins","volume":"1832","author":"Bartuzi","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.immuni.2017.06.018_bib2","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1158\/0008-5472.CAN-14-2173","article-title":"Emerging links between E2F control and mitochondrial function","volume":"75","author":"Benevolenskaya","year":"2015","journal-title":"Cancer Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib3","doi-asserted-by":"crossref","first-page":"4587","DOI":"10.1093\/nar\/gkp425","article-title":"An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia","volume":"37","author":"Benita","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib4","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1002\/art.27504","article-title":"Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis","volume":"62","author":"Cejka","year":"2010","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.immuni.2017.06.018_bib5","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/nm.1860","article-title":"Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption","volume":"14","author":"Chang","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.immuni.2017.06.018_bib6","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/jbmr.531","article-title":"Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP)","volume":"27","author":"Chiu","year":"2012","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib7","doi-asserted-by":"crossref","first-page":"R86","DOI":"10.1186\/gb-2010-11-8-r86","article-title":"Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences","volume":"11","author":"Goecks","year":"2010","journal-title":"Genome Biol."},{"key":"10.1016\/j.immuni.2017.06.018_bib8","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/jhg.2016.12","article-title":"Human genetic variation database, a reference database of genetic variations in the Japanese population","volume":"61","author":"Higasa","year":"2016","journal-title":"J.\u00a0Hum. Genet."},{"key":"10.1016\/j.immuni.2017.06.018_bib9","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1002\/jbmr.1976","article-title":"Metabolic regulation of osteoclast differentiation and function","volume":"28","author":"Indo","year":"2013","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nm.1910","article-title":"Coordination of PGC-1\u03b2 and iron uptake in mitochondrial biogenesis and osteoclast activation","volume":"15","author":"Ishii","year":"2009","journal-title":"Nat. Med."},{"key":"10.1016\/j.immuni.2017.06.018_bib11","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1038\/nm.3815","article-title":"Metabolic-epigenetic coupling in osteoclast differentiation","volume":"21","author":"Ivashkiv","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.immuni.2017.06.018_bib12","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/cr.2015.68","article-title":"Metabolic reprogramming in macrophages and dendritic cells in innate immunity","volume":"25","author":"Kelly","year":"2015","journal-title":"Cell Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib13","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.1172\/JCI26132","article-title":"M-CSF mediates TNF-induced inflammatory osteolysis","volume":"115","author":"Kitaura","year":"2005","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2017.06.018_bib14","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/nrrheum.2011.205","article-title":"Hypoxia--a key regulator of angiogenesis and inflammation in rheumatoid arthritis","volume":"8","author":"Konisti","year":"2012","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.immuni.2017.06.018_bib15","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S1074-7613(00)80045-X","article-title":"From systemic T\u00a0cell self-reactivity to organ-specific autoimmune disease via immunoglobulins","volume":"10","author":"Korganow","year":"1999","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2017.06.018_bib16","doi-asserted-by":"crossref","first-page":"16568","DOI":"10.1073\/pnas.1308755110","article-title":"HIF1\u03b1 is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis","volume":"110","author":"Miyauchi","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2017.06.018_bib17","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1083\/jcb.200806139","article-title":"Identification of cell cycle-arrested quiescent osteoclast precursors in\u00a0vivo","volume":"184","author":"Mizoguchi","year":"2009","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.immuni.2017.06.018_bib18","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/ng1180","article-title":"PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes","volume":"34","author":"Mootha","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.immuni.2017.06.018_bib19","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1600-0854.2009.00892.x","article-title":"Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity","volume":"10","author":"Muller","year":"2009","journal-title":"Traffic"},{"key":"10.1016\/j.immuni.2017.06.018_bib20","doi-asserted-by":"crossref","first-page":"2978","DOI":"10.1002\/jbmr.490","article-title":"Lineage-committed osteoclast precursors circulate in blood and settle down into bone","volume":"26","author":"Muto","year":"2011","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib21","doi-asserted-by":"crossref","first-page":"E13","DOI":"10.1111\/j.1749-6632.2011.06373.x","article-title":"New regulation mechanisms of osteoclast differentiation","volume":"1240","author":"Nakashima","year":"2011","journal-title":"Ann. N Y Acad. Sci."},{"key":"10.1016\/j.immuni.2017.06.018_bib22","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.ceb.2013.07.012","article-title":"The multiple connections between pRB and cell metabolism","volume":"25","author":"Nicolay","year":"2013","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.immuni.2017.06.018_bib23","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/nm.3774","article-title":"DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine-producing metabolic pathway","volume":"21","author":"Nishikawa","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.immuni.2017.06.018_bib24","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1146\/annurev.pathmechdis.3.121806.151431","article-title":"The osteoclast: friend or foe?","volume":"3","author":"Novack","year":"2008","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.immuni.2017.06.018_bib25","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.immuni.2014.09.008","article-title":"HIF transcription factors, inflammation, and immunity","volume":"41","author":"Palazon","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2017.06.018_bib26","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/jbmr.5650020617","article-title":"Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee","volume":"2","author":"Parfitt","year":"1987","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib27","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/jbmr.1739","article-title":"Negative regulation of osteoclast precursor differentiation by CD11b and \u03b22 integrin-B-cell lymphoma 6 signaling","volume":"28","author":"Park-Min","year":"2013","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib28","doi-asserted-by":"crossref","first-page":"5418","DOI":"10.1038\/ncomms6418","article-title":"Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation","volume":"5","author":"Park-Min","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.immuni.2017.06.018_bib29","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1093\/bioinformatics\/btq419","article-title":"LocusZoom: regional visualization of genome-wide association scan results","volume":"26","author":"Pruim","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.immuni.2017.06.018_bib30","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/nrrheum.2012.153","article-title":"Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment","volume":"8","author":"Schett","year":"2012","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.immuni.2017.06.018_bib31","doi-asserted-by":"crossref","first-page":"3664","DOI":"10.1172\/JCI67230","article-title":"HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations","volume":"123","author":"Semenza","year":"2013","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2017.06.018_bib32","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s00774-006-0725-9","article-title":"Characterization of osteoclasts derived from CD14+ monocytes isolated from peripheral blood","volume":"25","author":"S\u00f8rensen","year":"2007","journal-title":"J.\u00a0Bone Miner. Metab."},{"key":"10.1016\/j.immuni.2017.06.018_bib33","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2017.06.018_bib34","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.1002\/art.39306","article-title":"Rheumatoid factor is associated with the distribution of hand joint destruction in rheumatoid arthritis","volume":"67","author":"Terao","year":"2015","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.immuni.2017.06.018_bib35","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1093\/bioinformatics\/btp120","article-title":"TopHat: discovering splice junctions with RNA-Seq","volume":"25","author":"Trapnell","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.immuni.2017.06.018_bib36","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/nbt.1621","article-title":"Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation","volume":"28","author":"Trapnell","year":"2010","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.immuni.2017.06.018_bib37","doi-asserted-by":"crossref","first-page":"4142","DOI":"10.1128\/MCB.01932-06","article-title":"Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice","volume":"27","author":"van de Sluis","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.immuni.2017.06.018_bib38","doi-asserted-by":"crossref","first-page":"e7332","DOI":"10.1371\/journal.pone.0007332","article-title":"COMMD1 promotes pVHL and O2-independent proteolysis of HIF-1alpha via HSP90\/70","volume":"4","author":"van de Sluis","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.immuni.2017.06.018_bib39","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1172\/JCI40583","article-title":"COMMD1 disrupts HIF-1alpha\/beta dimerization and inhibits human tumor cell invasion","volume":"120","author":"van de Sluis","year":"2010","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2017.06.018_bib40","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/0092-8674(93)90510-W","article-title":"Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity","volume":"74","author":"van Deursen","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2017.06.018_bib41","doi-asserted-by":"crossref","first-page":"e29183","DOI":"10.1371\/journal.pone.0029183","article-title":"Liver-specific Commd1 knockout mice are susceptible to hepatic copper accumulation","volume":"6","author":"Vonk","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.immuni.2017.06.018_bib42","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.cmet.2010.04.015","article-title":"PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss","volume":"11","author":"Wei","year":"2010","journal-title":"Cell Metab."},{"key":"10.1016\/j.immuni.2017.06.018_bib43","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1038\/ng.2756","article-title":"Systematic identification of trans eQTLs as putative drivers of known disease associations","volume":"45","author":"Westra","year":"2013","journal-title":"Nat. Genet."},{"key":"10.1016\/j.immuni.2017.06.018_bib44","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/nrc3064","article-title":"Targeting hypoxia in cancer therapy","volume":"11","author":"Wilson","year":"2011","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.immuni.2017.06.018_bib45","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1038\/nrc2501","article-title":"Hypoxia signalling through mTOR and the unfolded protein response in cancer","volume":"8","author":"Wouters","year":"2008","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.immuni.2017.06.018_bib46","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1152\/physrev.2000.80.3.1107","article-title":"Creatine and creatinine metabolism","volume":"80","author":"Wyss","year":"2000","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.immuni.2017.06.018_bib47","doi-asserted-by":"crossref","first-page":"11846","DOI":"10.1074\/jbc.M512624200","article-title":"Tumor necrosis factor-\u03b1 increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression","volume":"281","author":"Yao","year":"2006","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.immuni.2017.06.018_bib48","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1002\/jbmr.2584","article-title":"Alternative NF-\u03baB regulates RANKL-induced osteoclast differentiation and mitochondrial biogenesis via independent mechanisms","volume":"30","author":"Zeng","year":"2015","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.immuni.2017.06.018_bib49","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1186\/ar3379","article-title":"Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors","volume":"13","author":"Zhao","year":"2011","journal-title":"Arthritis Res. Ther."}],"updated-by":[{"DOI":"10.1016\/j.immuni.2022.10.007","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T00:00:00Z","timestamp":1667865600000}}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761317302789?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761317302789?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T16:54:51Z","timestamp":1580489691000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761317302789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["S1074761317302789"],"URL":"https:\/\/doi.org\/10.1016\/j.immuni.2017.06.018","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.727821431.793534667","asserted-by":"object"}]},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis","name":"articletitle","label":"Article Title"},{"value":"Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2017.06.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}