{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T19:07:46Z","timestamp":1761419266847},"reference-count":9,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:00:00Z","timestamp":1574208000000},"content-version":"vor","delay-in-days":384,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.immuni.2018.11.002","type":"journal-article","created":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T10:37:12Z","timestamp":1542710232000},"page":"796-798","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Are Neuropeptide-Reactive T Cells behind Narcolepsy?"],"prefix":"10.1016","volume":"49","author":[{"given":"M. Elizabeth","family":"Deerhake","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William E.","family":"Barclay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari L.","family":"Shinohara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.immuni.2018.11.002_bib1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/s41586-018-0540-1","article-title":"T cells in patients with narcolepsy target self-antigens of hypocretin neurons","volume":"562","author":"Latorre","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2018.11.002_bib2","first-page":"1012","article-title":"HLA DQB1\u22170602 is associated with cataplexy in 509 narcoleptic patients","volume":"20","author":"Mignot","year":"1997","journal-title":"Sleep"},{"key":"10.1016\/j.immuni.2018.11.002_bib3","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/nri3294","article-title":"Unconventional recognition of peptides by T\u00a0cells and the implications for autoimmunity","volume":"12","author":"Mohan","year":"2012","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.immuni.2018.11.002_bib4","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1002\/ana.1130","article-title":"Low cerebrospinal fluid hypocretin (Orexin) and altered energy homeostasis in human narcolepsy","volume":"50","author":"Nishino","year":"2001","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.immuni.2018.11.002_bib5","doi-asserted-by":"crossref","first-page":"e33536","DOI":"10.1371\/journal.pone.0033536","article-title":"AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland","volume":"7","author":"Nohynek","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.immuni.2018.11.002_bib6","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/S1474-4422(14)70075-4","article-title":"Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination","volume":"13","author":"Partinen","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.immuni.2018.11.002_bib7","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.immuni.2017.01.007","article-title":"Dysregulation of the cytokine GM-CSF induces spontaneous phagocyte invasion and immunopathology in the central nervous system","volume":"46","author":"Spath","year":"2017","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2018.11.002_bib8","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0896-6273(00)00058-1","article-title":"Reduced number of hypocretin neurons in human narcolepsy","volume":"27","author":"Thannickal","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.immuni.2018.11.002_bib9","doi-asserted-by":"crossref","first-page":"220","DOI":"10.3389\/fnmol.2018.00220","article-title":"The orexin\/receptor system: Molecular mechanism and therapeutic potential for neurological diseases","volume":"11","author":"Wang","year":"2018","journal-title":"Front. Mol. Neurosci."}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761318304837?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761318304837?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T21:22:58Z","timestamp":1574198578000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761318304837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["S1074761318304837"],"URL":"https:\/\/doi.org\/10.1016\/j.immuni.2018.11.002","relation":{},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Are Neuropeptide-Reactive T Cells behind Narcolepsy?","name":"articletitle","label":"Article Title"},{"value":"Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2018.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}