{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:13:03Z","timestamp":1790403183616,"version":"4.1.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T00:00:00Z","timestamp":1667952000000},"content-version":"vor","delay-in-days":373,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.immuni.2021.10.016","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T11:52:53Z","timestamp":1636458773000},"page":"2439-2441","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Coagulation and immunity: Caught in the fibrin web"],"prefix":"10.1016","volume":"54","author":[{"given":"Elif G.","family":"Sozmen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina","family":"Akassoglou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.immuni.2021.10.016_bib1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0092-8674(00)81390-2","article-title":"Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency","volume":"87","author":"Bugge","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2021.10.016_bib2","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/35025229","article-title":"Thrombin signalling and protease-activated receptors","volume":"407","author":"Coughlin","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2021.10.016_bib3","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00281-011-0290-8","article-title":"Fibrinogen as a key regulator of inflammation in disease","volume":"34","author":"Davalos","year":"2012","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.immuni.2021.10.016_bib4","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1038\/ncomms2230","article-title":"Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation","volume":"3","author":"Davalos","year":"2012","journal-title":"Nat. Commun."},{"key":"10.1016\/j.immuni.2021.10.016_bib5","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1046\/j.1538-7836.2003.00261.x","article-title":"Inflammation and thrombosis","volume":"1","author":"Esmon","year":"2003","journal-title":"J.\u00a0Thromb. Haemost."},{"key":"10.1016\/j.immuni.2021.10.016_bib6","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1182\/blood-2018-07-818211","article-title":"The multifaceted role of fibrinogen in tissue injury and inflammation","volume":"133","author":"Luyendyk","year":"2019","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2021.10.016_bib7","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0140-6736(63)92808-3","article-title":"Reaction to antigens in\u00a0vivo of the peritoneal macrophages of guinea-pigs with delayed type hypersensitivity. Effects of anticoagulants and other drugs","volume":"2","author":"Nelson","year":"1963","journal-title":"Lancet"},{"key":"10.1016\/j.immuni.2021.10.016_bib8","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/nrn.2018.13","article-title":"Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics","volume":"19","author":"Petersen","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.immuni.2021.10.016_bib9","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1016\/j.immuni.2021.10.007","article-title":"Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity","volume":"54","author":"Vega-P\u00e9rez","year":"2021","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2021.10.016_bib10","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1084\/jem.20182024","article-title":"Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity","volume":"216","author":"Zhang","year":"2019","journal-title":"J.\u00a0Exp. Med."}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761321004532?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761321004532?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T08:12:48Z","timestamp":1761034368000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761321004532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S1074761321004532"],"URL":"https:\/\/doi.org\/10.1016\/j.immuni.2021.10.016","relation":{},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coagulation and immunity: Caught in the fibrin web","name":"articletitle","label":"Article Title"},{"value":"Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2021.10.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2021.10.007","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}