{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T20:25:51Z","timestamp":1793219151656,"version":"4.5.0"},"reference-count":76,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["715271"],"award-info":[{"award-number":["715271"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009139","name":"Deutsches Zentrum f\u00fcr Infektionsforschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009139","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005156","name":"Alexander von Humboldt-Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","award":["765492"],"award-info":[{"award-number":["765492"]}],"id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000011","name":"Howard Hughes Medical Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000011","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018515","name":"Hamburger Krebsgesellschaft eV","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018515","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003042","name":"Else Kr\u00f6ner-Fresenius-Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003042","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005972","name":"Deutsche Krebshilfe","doi-asserted-by":"publisher","award":["70112504"],"award-info":[{"award-number":["70112504"]}],"id":[{"id":"10.13039\/501100005972","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005972","name":"Deutsche Krebshilfe","doi-asserted-by":"publisher","award":["834974"],"award-info":[{"award-number":["834974"]}],"id":[{"id":"10.13039\/501100005972","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007013","name":"F. Hoffmann-La Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004038","name":"Jung Foundation for Science and Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017519","name":"Werner Otto Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017519","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008272","name":"Novartis Pharmaceuticals Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB841"],"award-info":[{"award-number":["SFB841"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB1328"],"award-info":[{"award-number":["SFB1328"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["LA3373\/6-1"],"award-info":[{"award-number":["LA3373\/6-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["50552-1"],"award-info":[{"award-number":["50552-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB-TRR 338\/1 2021\\u2013452881907"],"award-info":[{"award-number":["SFB-TRR 338\/1 2021\\u2013452881907"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"European Research Council","doi-asserted-by":"publisher","award":["CoG 865466"],"award-info":[{"award-number":["CoG 865466"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"European Research Council","doi-asserted-by":"publisher","award":["StG 756017"],"award-info":[{"award-number":["StG 756017"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010124","name":"Erich und Gertrud Roggenbuck Stiftung zur Forderung der Krebsforschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010124","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["800924"],"award-info":[{"award-number":["800924"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.immuni.2022.12.014","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T13:10:36Z","timestamp":1673356236000},"page":"125-142.e12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"title":["Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22"],"prefix":"10.1016","volume":"56","author":[{"given":"Anastasios D.","family":"Giannou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Kempski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Mustafa","family":"Shiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6081-479X","authenticated-orcid":false,"given":"J\u00f6ran","family":"L\u00fccke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitra E.","family":"Zazara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0176-067X","authenticated-orcid":false,"given":"Filippo","family":"Cortesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristoffer","family":"Riecken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9631-1249","authenticated-orcid":false,"given":"Maria Carolina","family":"Amezcua Vesely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Siong","family":"Low","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleanna","family":"Kaffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Garcia-Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodora","family":"Agalioti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshito","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1442-4862","authenticated-orcid":false,"given":"Wolfgang","family":"Jungraithmayr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehud","family":"Zigmond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5070-874X","authenticated-orcid":false,"given":"Karl-Frederick","family":"Karstens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babett","family":"Steglich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonie","family":"Konczalla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Carambia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kornelius","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"von Felden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9045-0595","authenticated-orcid":false,"given":"Peter","family":"May","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Briukhovetska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Bedke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonie","family":"Brockmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Starzonek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Koch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Riethdorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penelope","family":"Pelczar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius","family":"B\u00f6ttcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morsal","family":"Sabihi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis J.","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Reeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Kristin","family":"Grass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramez","family":"Wahib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannes","family":"Seese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn-Ole","family":"St\u00fcben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Fard-Aghaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Dupr\u00e9e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Scognamiglio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Plitzko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Meiners","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiwa","family":"Soukou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnes","family":"Wittek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Manthey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis C.","family":"Maroulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2932-926X","authenticated-orcid":false,"given":"Petra C.","family":"Arck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3083-3244","authenticated-orcid":false,"given":"Sotirios G.","family":"Zarogiannis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0185-1459","authenticated-orcid":false,"given":"Till","family":"Strowig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Pasqualini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wadih","family":"Arap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier Su\u00e1rez","family":"Gos\u00e1lvez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Kobold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Immo","family":"Prinz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas H.","family":"Guse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Tachezy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarik","family":"Ghadban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmus","family":"Heumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1553-8105","authenticated-orcid":false,"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel","family":"Melling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob R.","family":"Izbicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Pantel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udo","family":"Schumacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ansgar W.","family":"Lohse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Flavell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Gagliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9325-8227","authenticated-orcid":false,"given":"Samuel","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.immuni.2022.12.014_bib1","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.ccell.2021.03.004","article-title":"Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver","volume":"39","author":"Bertocchi","year":"2021","journal-title":"Cancer Cell"},{"key":"10.1016\/j.immuni.2022.12.014_bib2","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/s41577-019-0271-z","article-title":"Immune crosstalk in cancer progression and metastatic spread: a complex conversation","volume":"20","author":"Garner","year":"2020","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib3","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/ni1240","article-title":"Chemokine receptor CCR7 guides T\u00a0cell exit from peripheral tissues and entry into afferent lymphatics","volume":"6","author":"Bromley","year":"2005","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib4","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.immuni.2016.08.011","article-title":"Liver-resident memory CD8(+) T\u00a0cells form a front-line defense against malaria liver-stage infection","volume":"45","author":"Fernandez-Ruiz","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2022.12.014_bib5","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/s41586-018-0812-9","article-title":"Tissue-resident memory CD8+ T\u00a0cells promote melanoma\u2013immune equilibrium in skin","volume":"565","author":"Park","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2022.12.014_bib6","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1038\/s41591-018-0078-7","article-title":"Single-cell profiling of breast cancer T\u00a0cells reveals a tissue-resident memory subset associated with improved prognosis","volume":"24","author":"Savas","year":"2018","journal-title":"Nat. Med."},{"key":"10.1016\/j.immuni.2022.12.014_bib7","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1146\/annurev-immunol-032713-120243","article-title":"Biology of CD1- and MR1-Restricted T Cells","volume":"32","author":"Salio","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib8","doi-asserted-by":"crossref","first-page":"4031","DOI":"10.1172\/JCI93396","article-title":"Clinically resolved psoriatic lesions contain psoriasis-specific IL-17-producing \u03b1\u03b2 T\u00a0cell clones","volume":"127","author":"Matos","year":"2017","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2022.12.014_bib9","doi-asserted-by":"crossref","first-page":"8816","DOI":"10.1074\/jbc.M111.304758","article-title":"Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages","volume":"287","author":"Paget","year":"2012","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.immuni.2022.12.014_bib10","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/ni.1841","article-title":"Raising the NKT cell family","volume":"11","author":"Godfrey","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cellimm.2008.10.002","article-title":"Murine NKT cells produce Th17 cytokine interleukin-22","volume":"254","author":"Goto","year":"2009","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib12","doi-asserted-by":"crossref","first-page":"4457","DOI":"10.1038\/s41467-020-18262-6","article-title":"Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity","volume":"11","author":"Yang","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.immuni.2022.12.014_bib13","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/imr.12027","article-title":"IL-22, not simply a Th17 cytokine","volume":"252","author":"Rutz","year":"2013","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.immuni.2022.12.014_bib14","doi-asserted-by":"crossref","first-page":"12994","DOI":"10.1073\/pnas.1705165114","article-title":"Cancer cells induce interleukin-22 production from memory CD4(+) T\u00a0cells via interleukin-1 to promote tumor growth","volume":"114","author":"Voigt","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2022.12.014_bib15","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/j.biopha.2018.04.147","article-title":"Analysis of Th22, Th17 and CD4+cells co-producing IL-17\/IL-22 at different stages of human colon cancer","volume":"103","author":"Doulabi","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.immuni.2022.12.014_bib16","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.1038\/s41467-020-16363-w","article-title":"TGF-\u03b2 signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer","volume":"11","author":"Perez","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.immuni.2022.12.014_bib17","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.3389\/fonc.2019.01002","article-title":"TH9, TH17, and TH22 cell subsets and their main cytokine products in the pathogenesis of colorectal cancer","volume":"9","author":"Cui","year":"2019","journal-title":"Front. Oncol."},{"key":"10.1016\/j.immuni.2022.12.014_bib18","first-page":"3573","article-title":"Th22 cells represent a distinct human T\u00a0cell subset involved in epidermal immunity and remodeling","volume":"119","author":"Eyerich","year":"2009","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2022.12.014_bib19","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/s41586-019-0899-7","article-title":"Interleukin-22 protects intestinal stem cells against genotoxic stress","volume":"566","author":"Gronke","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2022.12.014_bib20","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/nature16460","article-title":"Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration","volume":"528","author":"Lindemans","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2022.12.014_bib21","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1084\/jem.20102149","article-title":"Memory\/effector (CD45RB(lo)) CD4 T\u00a0cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology","volume":"208","author":"Kamanaka","year":"2011","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2022.12.014_bib22","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nature11535","article-title":"IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine","volume":"491","author":"Huber","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2022.12.014_bib23","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1084\/jem.20122308","article-title":"Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model","volume":"210","author":"Kirchberger","year":"2013","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2022.12.014_bib24","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.immuni.2014.03.010","article-title":"IL-22(+)CD4(+) T\u00a0cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L","volume":"40","author":"Kryczek","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2022.12.014_bib25","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1158\/2326-6066.CIR-17-0655","article-title":"IL22 promotes Kras-mutant lung cancer by induction of a protumor immune response and protection of stemness properties","volume":"6","author":"Khosravi","year":"2018","journal-title":"Cancer Immunol. Res."},{"key":"10.1016\/j.immuni.2022.12.014_bib26","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1002\/hep.24486","article-title":"Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3","volume":"54","author":"Jiang","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.immuni.2022.12.014_bib27","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2407-13-59","article-title":"IL-22 is related to development of human colon cancer by activation of STAT3","volume":"13","author":"Jiang","year":"2013","journal-title":"BMC Cancer"},{"key":"10.1016\/j.immuni.2022.12.014_bib28","doi-asserted-by":"crossref","first-page":"4313","DOI":"10.1158\/1078-0432.CCR-19-1086","article-title":"The interleukin 22 Pathway interacts with mutant KRAS to promote poor prognosis in colon cancer","volume":"26","author":"McCuaig","year":"2020","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.immuni.2022.12.014_bib29","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1245\/s10434-013-3322-x","article-title":"High expression of interleukin-22 and its receptor predicts poor prognosis in pancreatic ductal adenocarcinoma","volume":"21","author":"Wen","year":"2014","journal-title":"Ann. Surg Oncol."},{"key":"10.1016\/j.immuni.2022.12.014_bib30","doi-asserted-by":"crossref","first-page":"672","DOI":"10.15252\/emmm.201606978","article-title":"NRAS destines tumor cells to the lungs","volume":"9","author":"Giannou","year":"2017","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.immuni.2022.12.014_bib31","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.4049\/jimmunol.1400588","article-title":"Acute and chronic effects of IL-22 on acetaminophen-induced liver injury","volume":"193","author":"Feng","year":"2014","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib32","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1073\/pnas.0908682107","article-title":"Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment","volume":"107","author":"Hung","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2022.12.014_bib33","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1093\/carcin\/bgq046","article-title":"A new conditional Apc -mutant mouse model for colorectal cancer","volume":"31","author":"Robanus-Maandag","year":"2010","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.immuni.2022.12.014_bib34","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1002\/dvdy.20643","article-title":"VE-Cadherin-Cre-recombinase transgenic mouse: A tool for lineage analysis and gene deletion in endothelial cells","volume":"235","author":"Alva","year":"2006","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.immuni.2022.12.014_bib35","doi-asserted-by":"crossref","first-page":"4078","DOI":"10.4049\/jimmunol.1700587","article-title":"A protective function of IL-22BP in ischemia reperfusion and acetaminophen-induced liver injury","volume":"199","author":"Kleinschmidt","year":"2017","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib36","doi-asserted-by":"crossref","first-page":"20717","DOI":"10.1073\/pnas.1321139110","article-title":"CD13-positive bone marrow-derived myeloid cells promote angiogenesis, tumor growth, and metastasis","volume":"110","author":"Dondossola","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2022.12.014_bib37","doi-asserted-by":"crossref","first-page":"23682","DOI":"10.1038\/srep23682","article-title":"ROR\u03b3t+ cells selectively express redundant cation channels linked to the Golgi apparatus","volume":"6","author":"Drujont","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.immuni.2022.12.014_bib38","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.cell.2019.07.032","article-title":"Effector TH17 cells give rise to long-lived TRM cells that are essential for an immediate response against bacterial infection","volume":"178","author":"Amezcua Vesely","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2022.12.014_bib39","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41392-020-0134-x","article-title":"Molecular principles of metastasis: a hallmark of cancer revisited","volume":"5","author":"Fares","year":"2020","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.immuni.2022.12.014_bib40","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/nature10138","article-title":"CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis","volume":"475","author":"Qian","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2022.12.014_bib41","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.immuni.2013.10.003","article-title":"Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer","volume":"39","author":"Bindea","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2022.12.014_bib42","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/nature14282","article-title":"IL-17-producing \u03b3\u03b4 T\u00a0cells and neutrophils conspire to promote breast cancer metastasis","volume":"522","author":"Coffelt","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2022.12.014_bib43","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.immuni.2016.02.025","article-title":"Integrative analyses of colorectal cancer show immunoscore is a stronger predictor of patient survival than microsatellite instability","volume":"44","author":"Mlecnik","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2022.12.014_bib44","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1073\/pnas.1120790109","article-title":"Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment","volume":"109","author":"Guzman-Rojas","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2022.12.014_bib45","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1371\/journal.pbio.0030113","article-title":"Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids","volume":"3","author":"Geissmann","year":"2005","journal-title":"PLoS Biol."},{"key":"10.1016\/j.immuni.2022.12.014_bib46","doi-asserted-by":"crossref","first-page":"eaan5931","DOI":"10.1126\/science.aan5931","article-title":"Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells","volume":"360","author":"Ma","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.immuni.2022.12.014_bib47","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1161\/CIRCULATIONAHA.119.041433","article-title":"Single-cell RNA sequencing unveils unique transcriptomic signatures of organ-specific endothelial cells","volume":"142","author":"Paik","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.immuni.2022.12.014_bib48","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/cam4.2673","article-title":"Metastatic patterns and survival outcomes in patients with stage IV colon cancer: A population-based analysis","volume":"9","author":"Wang","year":"2020","journal-title":"Cancer Med."},{"key":"10.1016\/j.immuni.2022.12.014_bib49","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1242\/jcs.069443","article-title":"Visualizing extravasation dynamics of metastatic tumor cells","volume":"123","author":"Stoletov","year":"2010","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.immuni.2022.12.014_bib50","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.jaad.2018.01.016","article-title":"Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double-blind, phase 2a trial","volume":"78","author":"Guttman-Yassky","year":"2018","journal-title":"J.\u00a0Am. Acad. Dermatol."},{"key":"10.1016\/j.immuni.2022.12.014_bib51","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1038\/nbt.2858","article-title":"Development and function of human innate immune cells in a humanized mouse model","volume":"32","author":"Rongvaux","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.immuni.2022.12.014_bib52","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.clim.2013.02.007","article-title":"Elevated serum IL-22 levels correlate with chemoresistant condition of colorectal cancer","volume":"147","author":"Wu","year":"2013","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib53","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1084\/jem.20102630","article-title":"PLZF induces an intravascular surveillance program mediated by long-lived LFA-1\u2013ICAM-1 interactions","volume":"208","author":"Thomas","year":"2011","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2022.12.014_bib54","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1084\/jem.20181483","article-title":"A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets","volume":"216","author":"Salou","year":"2019","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2022.12.014_bib55","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1158\/2159-8290.CD-19-0569","article-title":"MAIT cells promote tumor initiation, growth, and metastases via tumor MR1","volume":"10","author":"Yan","year":"2020","journal-title":"Cancer Discov."},{"key":"10.1016\/j.immuni.2022.12.014_bib56","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/mi.2017.34","article-title":"Unique invariant natural killer T\u00a0cells promote intestinal polyps by suppressing TH1 immunity and promoting regulatory T\u00a0cells","volume":"11","author":"Wang","year":"2018","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib57","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.3389\/fimmu.2019.01126","article-title":"\u03b1-GalCer and iNKT cell-based cancer immunotherapy: realizing the therapeutic potentials","volume":"10","author":"Zhang","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.immuni.2022.12.014_bib58","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nature24293","article-title":"IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity","volume":"551","author":"Molgora","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2022.12.014_bib59","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/mt.2008.6","article-title":"A multicolor panel of novel lentiviral \u201cGene Ontology\u201d (LeGO) vectors for functional gene analysis","volume":"16","author":"Weber","year":"2008","journal-title":"Mol. Ther."},{"key":"10.1016\/j.immuni.2022.12.014_bib60","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1053\/j.gastro.2016.11.019","article-title":"Inhibitor of apoptosis protein-1 regulates tumor necrosis factor\u2013mediated destruction of intestinal epithelial cells","volume":"152","author":"Grabinger","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.immuni.2022.12.014_bib61","doi-asserted-by":"crossref","first-page":"e106921","DOI":"10.1371\/journal.pone.0106921","article-title":"Radioimmunoimaging of liver metastases with PET using a 64Cu-labeled CEA antibody in transgenic mice","volume":"9","author":"Nittka","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.immuni.2022.12.014_bib62","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/1476-4598-13-244","article-title":"Perforin-dependent direct cytotoxicity in natural killer cells induces considerable knockdown of spontaneous lung metastases and computer modelling-proven tumor cell dormancy in a HT29 human colon cancer xenograft mouse model","volume":"13","author":"Brodbeck","year":"2014","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.immuni.2022.12.014_bib63","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1158\/0008-5472.CAN-17-3415","article-title":"Blockade of myeloid-derived suppressor cell expansion with all-trans retinoic acid increases the efficacy of antiangiogenic therapy","volume":"78","author":"Bauer","year":"2018","journal-title":"Cancer Res."},{"key":"10.1016\/j.immuni.2022.12.014_bib64","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/nature10228","article-title":"Control of TH17 cells occurs in the small intestine","volume":"475","author":"Esplugues","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2022.12.014_bib65","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.immuni.2011.01.020","article-title":"Th17 cells express interleukin-10 receptor and are controlled by Foxp3\u207b and Foxp3+ regulatory CD4+ T\u00a0cells in an interleukin-10-dependent manner","volume":"34","author":"Huber","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2022.12.014_bib66","doi-asserted-by":"crossref","first-page":"5126","DOI":"10.1073\/pnas.0501701102","article-title":"Identifying Foxp3-expressing suppressor T\u00a0cells with a bicistronic reporter","volume":"102","author":"Wan","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2022.12.014_bib67","first-page":"51677","article-title":"A preclinical murine model of hepatic metastases","author":"Soares","year":"2014","journal-title":"JoVE"},{"key":"10.1016\/j.immuni.2022.12.014_bib68","doi-asserted-by":"crossref","first-page":"4529","DOI":"10.1172\/JCI82826","article-title":"PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response","volume":"125","author":"Liao","year":"2015","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2022.12.014_bib69","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1126\/science.aah5903","article-title":"A pathogenic role for T cell\u2013derived IL-22BP in inflammatory bowel disease","volume":"354","author":"Pelczar","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.immuni.2022.12.014_bib70","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00418-011-0804-4","article-title":"Adhesion of small cell lung cancer cells to E- and P-Selectin under physiological flow conditions: implications for metastasis formation","volume":"135","author":"Richter","year":"2011","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.immuni.2022.12.014_bib71","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.jtcvs.2008.10.007","article-title":"A mouse model of orthotopic, single-lung transplantation","volume":"137","author":"Jungraithmayr","year":"2009","journal-title":"J.\u00a0Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.immuni.2022.12.014_bib72","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1172\/JCI79840","article-title":"Mast cells mediate malignant pleural effusion formation","volume":"125","author":"Giannou","year":"2015","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.immuni.2022.12.014_bib73","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nbt.4096","article-title":"Integrating single-cell transcriptomic data across different conditions, technologies, and species","volume":"36","author":"Butler","year":"2018","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.immuni.2022.12.014_bib74","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1186\/s13059-019-1874-1","article-title":"Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression","volume":"20","author":"Hafemeister","year":"2019","journal-title":"Genome Biol."},{"key":"10.1016\/j.immuni.2022.12.014_bib75","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1016\/j.cell.2019.05.031","article-title":"Comprehensive Integration of Single-Cell Data","volume":"177","author":"Stuart","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2022.12.014_bib76","doi-asserted-by":"crossref","first-page":"eaas9673","DOI":"10.1126\/sciimmunol.aas9673","article-title":"Location, location, location: tissue resident memory T\u00a0cells in mice and humans","volume":"4","author":"Szabo","year":"2019","journal-title":"Sci. Immunol."}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761322006501?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761322006501?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T12:10:55Z","timestamp":1778587855000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761322006501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":76,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S1074761322006501"],"URL":"https:\/\/doi.org\/10.1016\/j.immuni.2022.12.014","relation":{},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22","name":"articletitle","label":"Article Title"},{"value":"Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2022.12.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2022.12.010","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}