{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T20:13:50Z","timestamp":1792872830074,"version":"4.5.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"vor","delay-in-days":373,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012245","name":"Science and Technology Planning Project of Guangdong Province","doi-asserted-by":"publisher","award":["2022A0505050040"],"award-info":[{"award-number":["2022A0505050040"]}],"id":[{"id":"10.13039\/501100012245","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32200721"],"award-info":[{"award-number":["32200721"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022706","name":"Cole Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022706","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005326","name":"Yale University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005326","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"CIHR","doi-asserted-by":"publisher","award":["PJT166140"],"award-info":[{"award-number":["PJT166140"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"CIHR","doi-asserted-by":"publisher","award":["PJT178296"],"award-info":[{"award-number":["PJT178296"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007824","name":"Soochow University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007824","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019310","name":"Feinstein Institutes for Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019310","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.immuni.2024.04.023","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T10:35:06Z","timestamp":1715942106000},"page":"1603-1617.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation"],"prefix":"10.1016","volume":"57","author":[{"given":"Xin","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weili","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengxing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liying","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Calderon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenhua","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woong-Kyung","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tengfei","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongrui","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe-Xiong","family":"Lian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.immuni.2024.04.023_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2016.39","article-title":"Systemic lupus erythematosus","volume":"2","author":"Kaul","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.immuni.2024.04.023_bib2","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.immuni.2006.08.010","article-title":"Type I interferon in systemic lupus erythematosus and other autoimmune diseases","volume":"25","author":"Banchereau","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib3","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41586-022-04642-z","article-title":"TLR7 gain-of-function genetic variation causes human lupus","volume":"605","author":"Brown","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2024.04.023_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.02496","article-title":"Monogenic lupus: A developing paradigm of disease","volume":"9","author":"Alperin","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib5","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/art.39020","article-title":"Circulating follicular helper-like T\u00a0cells in systemic lupus erythematosus: association with disease activity","volume":"67","author":"Choi","year":"2015","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.immuni.2024.04.023_bib6","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.immuni.2014.10.004","article-title":"T follicular helper cell differentiation, function, and roles in disease","volume":"41","author":"Crotty","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib7","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1038\/cmi.2010.18","article-title":"Multiple checkpoints keep follicular helper T\u00a0cells under control to prevent autoimmunity","volume":"7","author":"Yu","year":"2010","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib8","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nrrheum.2012.58","article-title":"Follicular helper T\u00a0cells in immunity and systemic autoimmunity","volume":"8","author":"Craft","year":"2012","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.immuni.2024.04.023_bib9","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1084\/jem.20081886","article-title":"Follicular helper T\u00a0cells are required for systemic autoimmunity","volume":"206","author":"Linterman","year":"2009","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2024.04.023_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.immuni.2018.12.023","article-title":"The transcription factor Ets1 suppresses T follicular helper type 2 cell differentiation to halt the onset of systemic lupus erythematosus","volume":"50","author":"Kim","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib11","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/nature03555","article-title":"A RING-type ubiquitin ligase family member required to repress follicular helper T\u00a0cells and autoimmunity","volume":"435","author":"Vinuesa","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2024.04.023_bib12","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1146\/annurev-immunol-031210-101400","article-title":"Follicular helper CD4 T\u00a0cells (TFH)","volume":"29","author":"Crotty","year":"2011","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib13","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.immuni.2011.09.009","article-title":"Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells","volume":"35","author":"Pepper","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib14","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.immuni.2009.07.002","article-title":"The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment","volume":"31","author":"Yu","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib15","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1126\/science.1175870","article-title":"Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation","volume":"325","author":"Johnston","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.immuni.2024.04.023_bib16","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1126\/science.1176676","article-title":"Bcl6 mediates the development of T follicular helper cells","volume":"325","author":"Nurieva","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.immuni.2024.04.023_bib17","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1038\/ni.3226","article-title":"LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6","volume":"16","author":"Choi","year":"2015","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib18","doi-asserted-by":"crossref","first-page":"3997","DOI":"10.1182\/blood-2011-11-392985","article-title":"Functional STAT3 deficiency compromises the generation of human T follicular helper cells","volume":"119","author":"Ma","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.immuni.2024.04.023_bib19","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.4049\/jimmunol.1203032","article-title":"Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation","volume":"190","author":"Choi","year":"2013","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib20","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1084\/jem.20111174","article-title":"STAT5 is a potent negative regulator of TFH cell differentiation","volume":"209","author":"Johnston","year":"2012","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.immuni.2024.04.023_bib21","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.immuni.2015.01.017","article-title":"ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation","volume":"42","author":"Stone","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib22","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.tcb.2012.05.006","article-title":"Chaperone-mediated autophagy: a unique way to enter the lysosome world","volume":"22","author":"Kaushik","year":"2012","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.immuni.2024.04.023_bib23","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0968-0004(90)90019-8","article-title":"Peptide sequences that target cytosolic proteins for lysosomal proteolysis","volume":"15","author":"Dice","year":"1990","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.immuni.2024.04.023_bib24","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/s41580-018-0001-6","article-title":"The coming of age of chaperone-mediated autophagy","volume":"19","author":"Kaushik","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.immuni.2024.04.023_bib25","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/ncb0910-823","article-title":"Autophagy in mammalian development and differentiation","volume":"12","author":"Mizushima","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.immuni.2024.04.023_bib26","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.mam.2011.09.001","article-title":"Autophagy, nutrition and immunology","volume":"33","author":"Cuervo","year":"2012","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.immuni.2024.04.023_bib27","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1038\/ni.3003","article-title":"Chaperone-mediated autophagy regulates T\u00a0cell responses through targeted degradation of negative regulators of T\u00a0cell activation","volume":"15","author":"Valdor","year":"2014","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib28","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.immuni.2004.06.012","article-title":"The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling","volume":"21","author":"Duan","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib29","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1038\/ni855","article-title":"c-Cbl and Cbl-b regulate T\u00a0cell responsiveness by promoting ligand-induced TCR down-modulation","volume":"3","author":"Naramura","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib30","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.immuni.2006.08.021","article-title":"Establishment of the major compatibility complex-dependent development of CD4+ and CD8+ T\u00a0cells by the Cbl family proteins","volume":"25","author":"Huang","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib31","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.immuni.2007.03.015","article-title":"Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b","volume":"26","author":"Kitaura","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib32","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1177\/0961203310394896","article-title":"Expression and function of Cbl-b in T\u00a0cells from patients with systemic lupus erythematosus, and detection of the 2126 A\/G Cblb gene polymorphism in the Mexican mestizo population","volume":"20","author":"Don\u00edz-Padilla","year":"2011","journal-title":"Lupus"},{"key":"10.1016\/j.immuni.2024.04.023_bib33","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1177\/0961203314567750","article-title":"Circulating CXCR5+CD4+helper T\u00a0cells in systemic lupus erythematosus patients share phenotypic properties with germinal center follicular helper T\u00a0cells and promote antibody production","volume":"24","author":"Zhang","year":"2015","journal-title":"Lupus"},{"key":"10.1016\/j.immuni.2024.04.023_bib34","doi-asserted-by":"crossref","DOI":"10.1126\/science.abf1970","article-title":"Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus","volume":"376","author":"Perez","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.immuni.2024.04.023_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.670637","article-title":"The OX40\/OX40L axis regulates T follicular helper cell differentiation: implications for autoimmune diseases","volume":"12","author":"Fu","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib36","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.immuni.2011.03.023","article-title":"ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6","volume":"34","author":"Choi","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib37","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.molimm.2007.08.002","article-title":"The Cbl-b RING finger domain has a limited role in regulating inflammatory cytokine production by IgE-activated mast cells","volume":"45","author":"Oksvold","year":"2008","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000301","article-title":"Proteome-wide analysis of chaperone-mediated autophagy targeting motifs","volume":"17","author":"Kirchner","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.immuni.2024.04.023_bib39","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202001031","article-title":"Inhibition of class I PI3K enhances chaperone-mediated autophagy","volume":"219","author":"Endicott","year":"2020","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.immuni.2024.04.023_bib40","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.molcel.2015.05.030","article-title":"Lysosomal mTORC2\/PHLPP1\/Akt regulate chaperone-mediated autophagy","volume":"59","author":"Arias","year":"2015","journal-title":"Mol. Cell"},{"key":"10.1016\/j.immuni.2024.04.023_bib41","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2000046","article-title":"PKC-theta modulates the strength of T\u00a0cell responses by targeting Cbl-b for ubiquitination and degradation","volume":"2","author":"Gruber","year":"2009","journal-title":"Sci. Signal."},{"key":"10.1016\/j.immuni.2024.04.023_bib42","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.4049\/jimmunol.169.5.2236","article-title":"Cutting edge: regulation of T\u00a0cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquitination","volume":"169","author":"Zhang","year":"2002","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib43","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.immuni.2019.04.011","article-title":"T follicular helper cell biology: A decade of discovery and diseases","volume":"50","author":"Crotty","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2024.04.023_bib44","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/s41590-020-0706-5","article-title":"Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits","volume":"21","author":"Choi","year":"2020","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib45","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.it.2021.02.002","article-title":"Bcl6-Mediated Transcriptional Regulation of Follicular Helper T\u00a0cells (T(FH))","volume":"42","author":"Choi","year":"2021","journal-title":"Trends Immunol."},{"key":"10.1016\/j.immuni.2024.04.023_bib46","doi-asserted-by":"crossref","first-page":"13324","DOI":"10.1073\/pnas.1507312112","article-title":"Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3","volume":"112","author":"Nance","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.immuni.2024.04.023_bib47","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.immuni.2018.03.006","article-title":"Cbl ubiquitin ligases control B cell exit from the germinal-center reaction","volume":"48","author":"Li","year":"2018","journal-title":"Immunity"}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761324002280?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761324002280?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T07:48:39Z","timestamp":1763365719000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761324002280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":47,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S1074761324002280"],"URL":"https:\/\/doi.org\/10.1016\/j.immuni.2024.04.023","relation":{},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation","name":"articletitle","label":"Article Title"},{"value":"Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2024.04.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}