{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:45:27Z","timestamp":1791924327765,"version":"4.3.4"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["25gm1910006h0002"],"award-info":[{"award-number":["25gm1910006h0002"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP20gm1210006"],"award-info":[{"award-number":["JP20gm1210006"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012331","name":"LEO Fondet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019270","name":"Shimizu Foundation for Immunology and Neuroscience","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["19K15980"],"award-info":[{"award-number":["19K15980"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25K02175"],"award-info":[{"award-number":["25K02175"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20H05697"],"award-info":[{"award-number":["20H05697"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20J00115"],"award-info":[{"award-number":["20J00115"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22K15010"],"award-info":[{"award-number":["22K15010"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25H00442"],"award-info":[{"award-number":["25H00442"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019432","name":"Fujiwara Memorial Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019432","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005926","name":"Cosmetology Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005926","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.immuni.2026.09.010","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:44:09Z","timestamp":1791816249000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Skin-resident CXCR6+ memory CD4+ T cells and dendritic cells form dermal perivascular hubs that drive relapse in allergic dermatitis"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8230-1960","authenticated-orcid":false,"given":"Ryota","family":"Asahina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuuka","family":"Minami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9332-0369","authenticated-orcid":false,"given":"Satoshi","family":"Nakamizo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiya","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4047-3016","authenticated-orcid":false,"given":"Satoru","family":"Yonekura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0683-719X","authenticated-orcid":false,"given":"Toshiaki","family":"Kogame","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1616-1349","authenticated-orcid":false,"given":"Shuto","family":"Kanameishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9585-5885","authenticated-orcid":false,"given":"Kosuke","family":"Katsuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5892-6138","authenticated-orcid":false,"given":"Hiroyuki","family":"Irie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0831-1447","authenticated-orcid":false,"given":"Saeko","family":"Nakajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4004-1339","authenticated-orcid":false,"given":"Takashi","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Kitoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6101-4719","authenticated-orcid":false,"given":"Gyohei","family":"Egawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0773-0554","authenticated-orcid":false,"given":"Kenji","family":"Kabashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.immuni.2026.09.010_bib1","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/s41577-023-00853-1","article-title":"Assessing the generation of tissue resident memory T cells by vaccines","volume":"23","author":"Rotrosen","year":"2023","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib2","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/nm.3883","article-title":"The emerging role of resident memory T cells in protective immunity and inflammatory disease","volume":"21","author":"Park","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.immuni.2026.09.010_bib3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/nri.2015.3","article-title":"Tissue-resident memory T cells: local specialists in immune defence","volume":"16","author":"Mueller","year":"2016","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib4","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aas9673","article-title":"Location, location, location: Tissue resident memory T cells in mice and humans","volume":"4","author":"Szabo","year":"2019","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib5","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/ni.1718","article-title":"Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus","volume":"10","author":"Gebhardt","year":"2009","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/nature10851","article-title":"Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity","volume":"483","author":"Jiang","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2026.09.010_bib7","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1126\/science.1254536","article-title":"T cell memory. Resident memory CD8 T cells trigger protective innate and adaptive immune responses","volume":"346","author":"Schenkel","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.immuni.2026.09.010_bib8","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3010641","article-title":"Resident memory T cells in human health and disease","volume":"7","author":"Clark","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.immuni.2026.09.010_bib9","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1038\/s41577-019-0162-3","article-title":"T cells and the skin: from protective immunity to inflammatory skin disorders","volume":"19","author":"Ho","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.01214","article-title":"Niches for the Long-Term Maintenance of Tissue-Resident Memory T Cells","volume":"9","author":"Takamura","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib11","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.immuni.2017.01.009","article-title":"CD49a Expression Defines Tissue-Resident CD8(+) T Cells Poised for Cytotoxic Function in Human Skin","volume":"46","author":"Cheuk","year":"2017","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2026.09.010_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.imlet.2022.02.009","article-title":"Heterogeneity of tissue resident memory T cells","volume":"245","author":"Konjar","year":"2022","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.immuni.2026.09.010_bib13","article-title":"Heterogeneity and plasticity of tissue-resident memory T cells in skin diseases and homeostasis: a review","volume":"15","author":"Liu","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib14","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/imr.13213","article-title":"Functional heterogeneity of human skin-resident memory T cells in health and disease","volume":"316","author":"Strobl","year":"2023","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.immuni.2026.09.010_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/cells10010164","article-title":"Functional Heterogeneity and Therapeutic Targeting of Tissue-Resident Memory T Cells","volume":"10","author":"van der Gracht","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.immuni.2026.09.010_bib16","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1084\/jem.20181365","article-title":"CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses","volume":"216","author":"Beura","year":"2019","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.immuni.2026.09.010_bib17","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1111\/all.13223","article-title":"Nonlesional atopic dermatitis skin shares similar T-cell clones with lesional tissues","volume":"72","author":"Brunner","year":"2017","journal-title":"Allergy"},{"key":"10.1016\/j.immuni.2026.09.010_bib18","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/j.jaci.2020.01.042","article-title":"Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis","volume":"145","author":"He","year":"2020","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.00775","article-title":"CD4+ Resident Memory T Cells Mediate Long-Term Local Skin Immune Memory of Contact Hypersensitivity in BALB\/C Mice","volume":"11","author":"Murata","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib20","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abe2749","article-title":"Persistence of mature dendritic cells, T(H)2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Ralpha blockade","volume":"6","author":"Bangert","year":"2021","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib21","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/bjd\/ljac008","article-title":"Interleukin-13 inhibition by tralokinumab reduces inducible T-cell costimulator-positive innate lymphoid cells in skin lesions of atopic dermatitis","volume":"188","author":"Kogame","year":"2023","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.immuni.2026.09.010_bib22","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s40257-022-00683-2","article-title":"Long-Term Efficacy and Safety of Dupilumab in Adolescents with Moderate-to-Severe Atopic Dermatitis: Results Through Week 52 from a Phase III Open-Label Extension Trial (Liberty AD PED-OLE)","volume":"23","author":"Blauvelt","year":"2022","journal-title":"Am. J. Clin. Dermatol."},{"key":"10.1016\/j.immuni.2026.09.010_bib23","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/s41590-017-0027-5","article-title":"Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses","volume":"19","author":"Park","year":"2018","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib24","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abb7028","article-title":"Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease","volume":"12","author":"Strobl","year":"2020","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.immuni.2026.09.010_bib25","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms11514","article-title":"Skin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation","volume":"7","author":"Collins","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.immuni.2026.09.010_bib26","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/nature10339","article-title":"Different patterns of peripheral migration by memory CD4+ and CD8+ T cells","volume":"477","author":"Gebhardt","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2026.09.010_bib27","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abq3254","article-title":"Local IL-23 is required for proliferation and retention of skin-resident memory T(H)17 cells","volume":"7","author":"Whitley","year":"2022","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib28","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1038\/s41590-019-0494-y","article-title":"CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells","volume":"20","author":"Ichikawa","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib29","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/all.15819","article-title":"Topical corticosteroids inhibit allergic skin inflammation but are ineffective in impeding the formation and expansion of resident memory T cells","volume":"79","author":"Ono","year":"2024","journal-title":"Allergy"},{"key":"10.1016\/j.immuni.2026.09.010_bib30","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.immuni.2013.08.029","article-title":"CD301b(+) dermal dendritic cells drive T helper 2 cell-mediated immunity","volume":"39","author":"Kumamoto","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2026.09.010_bib31","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.immuni.2019.08.013","article-title":"The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality","volume":"51","author":"Li","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2026.09.010_bib32","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aaw2938","article-title":"A key role for IL-13 signaling via the type 2 IL-4 receptor in experimental atopic dermatitis","volume":"5","author":"Bitton","year":"2020","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib33","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1038\/nm.3962","article-title":"Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma","volume":"21","author":"Adachi","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.immuni.2026.09.010_bib34","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/j.immuni.2015.11.008","article-title":"T-box Transcription Factors Combine with the Cytokines TGF-beta and IL-15 to Control Tissue-Resident Memory T Cell Fate","volume":"43","author":"Mackay","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.immuni.2026.09.010_bib35","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/bjd.19574","article-title":"Tralokinumab for moderate-to-severe atopic dermatitis: results from two 52-week, randomized, double-blind, multicentre, placebo-controlled phase III trials (ECZTRA 1 and ECZTRA 2)","volume":"184","author":"Wollenberg","year":"2021","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.immuni.2026.09.010_bib36","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.jaci.2020.03.041","article-title":"Single-cell transcriptomics combined with interstitial fluid proteomics defines cell type-specific immune regulation in atopic dermatitis","volume":"146","author":"Rojahn","year":"2020","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib37","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jaci.2023.04.019","article-title":"Single-cell RNA sequencing defines disease-specific differences between chronic nodular prurigo and atopic dermatitis","volume":"152","author":"Alkon","year":"2023","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib38","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.jaci.2023.11.017","article-title":"Resident memory T cells in nonlesional skin and healed lesions of patients with chronic inflammatory diseases: Appearances can be deceptive","volume":"153","author":"Migayron","year":"2024","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib39","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1126\/science.aad2035","article-title":"Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes","volume":"352","author":"Mackay","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.immuni.2026.09.010_bib40","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1016\/j.celrep.2017.08.078","article-title":"Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites","volume":"20","author":"Kumar","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.immuni.2026.09.010_bib41","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1038\/ni.3589","article-title":"Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells","volume":"17","author":"Hombrink","year":"2016","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib42","doi-asserted-by":"crossref","DOI":"10.1126\/science.aao0666","article-title":"Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles","volume":"362","author":"Choi","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.immuni.2026.09.010_bib43","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1126\/science.1257530","article-title":"T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells","volume":"346","author":"Iijima","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.immuni.2026.09.010_bib44","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1038\/ni.2744","article-title":"The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin","volume":"14","author":"Mackay","year":"2013","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib45","doi-asserted-by":"crossref","first-page":"4512","DOI":"10.1016\/j.cell.2021.07.015","article-title":"CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment","volume":"184","author":"Di Pilato","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2026.09.010_bib46","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1038\/ni.2992","article-title":"Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin","volume":"15","author":"Natsuaki","year":"2014","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib47","doi-asserted-by":"crossref","DOI":"10.3390\/cells13161398","article-title":"IL-22 in atopic dermatitis","volume":"13","author":"Laska","year":"2024","journal-title":"Cells"},{"key":"10.1016\/j.immuni.2026.09.010_bib48","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.4049\/jimmunol.165.6.3284","article-title":"The primate lentiviral receptor Bonzo\/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse","volume":"165","author":"Unutmaz","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib49","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/360225a0","article-title":"Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages","volume":"360","author":"Mombaerts","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.immuni.2026.09.010_bib50","doi-asserted-by":"crossref","DOI":"10.1038\/srep06030","article-title":"Tracking and quantification of dendritic cell migration and antigen trafficking between the skin and lymph nodes","volume":"4","author":"Tomura","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.immuni.2026.09.010_bib58","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.immuni.2026.09.010_bib59","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-21246-9","article-title":"Inference and analysis of cell-cell communication using CellChat","volume":"12","author":"Jin","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.immuni.2026.09.010_bib54","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.immuni.2026.09.010_bib55","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2105-12-323","article-title":"RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome","volume":"12","author":"Li","year":"2011","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.immuni.2026.09.010_bib56","doi-asserted-by":"crossref","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.immuni.2026.09.010_bib60","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-17204-5","article-title":"QuPath: Open source software for digital pathology image analysis","volume":"7","author":"Bankhead","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.immuni.2026.09.010_bib51","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/nprot.2012.032","article-title":"A transient parabiosis skin transplantation model in mice","volume":"7","author":"Duyverman","year":"2012","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.immuni.2026.09.010_bib52","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.4049\/jimmunol.171.4.1647","article-title":"Cutting edge: SR-PSOX\/CXC chemokine ligand 16 mediates bacterial phagocytosis by APCs through its chemokine domain","volume":"171","author":"Shimaoka","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.immuni.2026.09.010_bib53","doi-asserted-by":"crossref","DOI":"10.1038\/srep01932","article-title":"Intravital analysis of vascular permeability in mice using two-photon microscopy","volume":"3","author":"Egawa","year":"2013","journal-title":"Sci. Rep."},{"key":"10.1016\/j.immuni.2026.09.010_bib57","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/nmeth.4324","article-title":"Differential analysis of RNA-seq incorporating quantification uncertainty","volume":"14","author":"Pimentel","year":"2017","journal-title":"Nat. Methods"}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761326003857?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761326003857?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:53:33Z","timestamp":1791921213000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761326003857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":60,"alternative-id":["S1074761326003857"],"URL":"https:\/\/doi.org\/10.1016\/j.immuni.2026.09.010","relation":{},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Skin-resident CXCR6+ memory CD4+ T cells and dendritic cells form dermal perivascular hubs that drive relapse in allergic dermatitis","name":"articletitle","label":"Article Title"},{"value":"Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.immuni.2026.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}