{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:01:58Z","timestamp":1780362118189,"version":"3.54.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Integrative Medicine Research"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.imr.2024.101084","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T18:15:51Z","timestamp":1725646551000},"page":"101084","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Long-term follow-up of the treatment for severe COVID-19 with qigong exercise and acupressure: A randomized controlled trial"],"prefix":"10.1016","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4355-0980","authenticated-orcid":false,"given":"Shuting","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1414-573X","authenticated-orcid":false,"given":"Ranran","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6814-2238","authenticated-orcid":false,"given":"Chongjie","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5732-8857","authenticated-orcid":false,"given":"Chao","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5241-6460","authenticated-orcid":false,"given":"Min","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1928-8142","authenticated-orcid":false,"given":"Lei","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10223","key":"10.1016\/j.imr.2024.101084_bib0001","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China[J]","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.imr.2024.101084_bib0002","unstructured":"World Health Organization. WHO Coronavirus Disease (COVID-19) Dashboard. Accessed 17 February 2023. https:\/\/Covid19.who.int\/."},{"issue":"9","key":"10.1016\/j.imr.2024.101084_bib0003","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.31790","article-title":"Two-year health outcomes in hospitalized COVID-19 survivors in China","volume":"5","author":"Yang","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"8","key":"10.1016\/j.imr.2024.101084_bib0004","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.jagp.2020.05.012","article-title":"Qigong for the prevention, treatment, and rehabilitation of COVID-19 infection in older adults","volume":"28","author":"Feng","year":"2020","journal-title":"Am J Geriatr Psychiatry"},{"issue":"5","key":"10.1016\/j.imr.2024.101084_bib0005","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.chest.2018.01.053","article-title":"Tai Chi and pulmonary rehabilitation compared for treatment-naive patients with COPD: a randomized controlled trial","volume":"153","author":"Polkey","year":"2018","journal-title":"Chest"},{"issue":"7","key":"10.1016\/j.imr.2024.101084_bib0006","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1111\/jgs.13478","article-title":"Efficacy of liuzijue qigong in individuals with chronic obstructive pulmonary disease in remission","volume":"63","author":"Xiao","year":"2015","journal-title":"J Am Geriatr Soc"},{"issue":"2","key":"10.1016\/j.imr.2024.101084_bib0007","doi-asserted-by":"crossref","first-page":"e23548","DOI":"10.2196\/23548","article-title":"WeChat as a platform for baduanjin intervention in patients with stable chronic obstructive pulmonary disease in China: retrospective randomized controlled trial","volume":"9","author":"Bi","year":"2021","journal-title":"JMIR Mhealth Uhealth"},{"issue":"3","key":"10.1016\/j.imr.2024.101084_bib0008","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1046\/j.1365-2648.2003.02886.x","article-title":"Effectiveness of acupressure in improving dyspnoea in chronic obstructive pulmonary disease","volume":"45","author":"Wu","year":"2004","journal-title":"J Adv Nurs"},{"issue":"6","key":"10.1016\/j.imr.2024.101084_bib0009","first-page":"997","article-title":"Effectiveness of Liu-zi-jue exercise on coronavirus disease 2019 in the patients: a randomized controlled trial","volume":"42","author":"Qingguang","year":"2022","journal-title":"J Tradit Chin Med"},{"issue":"6","key":"10.1016\/j.imr.2024.101084_bib0010","doi-asserted-by":"crossref","first-page":"e24564","DOI":"10.1097\/MD.0000000000024564","article-title":"Liuzijue is a promising exercise option for rehabilitating discharged COVID-19 patients","volume":"100","author":"Tang","year":"2021","journal-title":"Medicine (Baltimore)"},{"issue":"5","key":"10.1016\/j.imr.2024.101084_bib0011","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.21037\/apm-20-753","article-title":"Modified rehabilitation exercises for mild cases of COVID-19","volume":"9","author":"Zha","year":"2020","journal-title":"Ann Palliat Med"},{"key":"10.1016\/j.imr.2024.101084_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.imr.2021.100796","article-title":"Effect of qigong exercise and acupressure rehabilitation program on pulmonary function and respiratory symptoms in patients hospitalized with severe COVID-19: a randomized controlled trial","volume":"10","author":"Liu","year":"2021","journal-title":"Integr Med Res"},{"issue":"27","key":"10.1016\/j.imr.2024.101084_bib0013","first-page":"100","article-title":"The effect of Liuzijue breathingexercises combined with acupoint massage on improving lung function and quality of life in elderly patients with COPD","volume":"57","author":"Junfang","year":"2019","journal-title":"Chin Mod Doct"},{"issue":"1","key":"10.1016\/j.imr.2024.101084_bib0014","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1186\/s13063-020-04693-5","article-title":"Acupressure therapy and Liu Zi Jue Qigong for pulmonary function and quality of life in patients with severe novel coronavirus pneumonia (COVID-19): a study protocol for a randomized controlled trial","volume":"21","author":"Zhang","year":"2020","journal-title":"Trials"},{"key":"10.1016\/j.imr.2024.101084_bib0015","unstructured":"Hygiene Emergency Office. Revision of \"New Coronavirus Pneumonia Diagnosis and Treatment Plan (Trial Eighth Edition)\" National Health Commission of the People's Republic of China home page 2020. https:\/\/www.nhc.gov.cn. Assessed by 15 March 2021."},{"issue":"7","key":"10.1016\/j.imr.2024.101084_bib0016","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/thx.54.7.581","article-title":"Usefulness of the medical research council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease","volume":"54","author":"Bestall","year":"1999","journal-title":"Thorax"},{"key":"10.1016\/j.imr.2024.101084_bib0017","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.rmed.2018.11.020","article-title":"Correlation of the modified medical research council dyspnea scale with airway structure assessed by three-dimensional CT in patients with chronic obstructive pulmonary disease","volume":"146","author":"Yasui","year":"2019","journal-title":"Respir Med"},{"issue":"3","key":"10.1016\/j.imr.2024.101084_bib0018","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S0099-1767(00)90093-X","article-title":"Usefulness of the modified 0-10 Borg scale in assessing the degree of dyspnea in patients with COPD and asthma","volume":"26","author":"Kendrick","year":"2000","journal-title":"J Emerg Nurs"},{"key":"10.1016\/j.imr.2024.101084_bib0019","doi-asserted-by":"crossref","first-page":"l1476","DOI":"10.1136\/bmj.l1476","article-title":"DEPRESsion screening data (DEPRESSD) collaboration. accuracy of patient health questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis","volume":"365","author":"Levis","year":"2019","journal-title":"BMJ"},{"issue":"9","key":"10.1016\/j.imr.2024.101084_bib0020","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: validity of a brief depression severity measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"J Gen Intern Med"},{"issue":"2","key":"10.1016\/j.imr.2024.101084_bib0021","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3109\/15412555.2014.922066","article-title":"An international comparison of pulmonary rehabilitation: a systematic review","volume":"12","author":"Desveaux","year":"2015","journal-title":"COPD"},{"key":"10.1016\/j.imr.2024.101084_bib0022","unstructured":"World Health Organization. The Who Global Report on Traditional and Complementary Medicine 2019 Is Released. Published 2019. Accessed Oct 01, 2022. https:\/\/www.who.int\/news\/item\/20-05-2019-the-who-global-report-on-traditional-and-complementary-medicine-2019-is-released."},{"issue":"61","key":"10.1016\/j.imr.2024.101084_bib0023","article-title":"Minimal clinically important difference and predictive validity of the mMRC and mBorg in acute exacerbations of COPD[J]","volume":"50","author":"Ara\u00fajo","year":"2017","journal-title":"Eur Respiratory J"},{"issue":"3","key":"10.1016\/j.imr.2024.101084_bib0024","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1164\/rccm.201310-1863PP","article-title":"Minimal clinically important differences in pharmacological trials[J]","volume":"189","author":"Jones","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"10.1016\/j.imr.2024.101084_bib0025","first-page":"42","article-title":"Clinical efficacy of acupressure combined with traditional Chinese medicine application in the treatment of acute exacerbation of chronic obstructive pulmonary disease and its effect on inflammatory indexes","volume":"31","author":"Hu","year":"2023","journal-title":"Chinese Folk Therapy"},{"issue":"20","key":"10.1016\/j.imr.2024.101084_bib0026","first-page":"153","article-title":"Clinical study of Xuanfei decoction combined with traditional Chinese medicine acupoint patch for the treatment of acute exacerbation of chronic obstructive pulmonary disease combined with respiratory failure","volume":"55","author":"Jiang","year":"2023","journal-title":"New Chinese Medicine"},{"issue":"1","key":"10.1016\/j.imr.2024.101084_bib0027","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1186\/s12906-022-03789-6","article-title":"Effect of Liuzijue on pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: study protocol for a multicenter, non-randomized, prospective study","volume":"22","author":"Hu","year":"2022","journal-title":"BMC Complement Med Ther"},{"issue":"4","key":"10.1016\/j.imr.2024.101084_bib0028","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1378\/chest.121.4.1092","article-title":"Power of outcome measurements to detect clinically significant changes in pulmonary rehabilitation of patients with COPD","volume":"121","author":"de Torres","year":"2002","journal-title":"Chest"},{"key":"10.1016\/j.imr.2024.101084_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2022.106984","article-title":"Qualitative validation of the modified Medical Research Council (mMRC) dyspnoea scale as a patient-reported measure of breathlessness severity","volume":"203","author":"Sunjaya","year":"2022","journal-title":"Respir Med"},{"issue":"1","key":"10.1016\/j.imr.2024.101084_bib0030","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1183\/09031936.99.14614549","article-title":"Physiological changes in respiratory func-tion associated with ageing","volume":"13","author":"Janssens","year":"1999","journal-title":"Eur Respir J"},{"key":"10.1016\/j.imr.2024.101084_bib0031","first-page":"1489","article-title":"The aging lung","volume":"8","author":"Lowery","year":"2013","journal-title":"Clin Interv Aging"},{"key":"10.1016\/j.imr.2024.101084_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.archger.2021.104411","article-title":"Nutritional determinants and COVID-19 outcomes of older patients with COVID-19: a systematic review","volume":"95","author":"Damayanthi","year":"2021","journal-title":"Arch Gerontol Geriatr"},{"issue":"4","key":"10.1016\/j.imr.2024.101084_bib0033","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1007\/s11357-020-00218-9","article-title":"Elderly at time of COronaVIrus disease 2019 (COVID-19): possible role of immunosenescence and malnutrition","volume":"42","author":"Bencivenga","year":"2020","journal-title":"Geroscience"},{"issue":"5","key":"10.1016\/j.imr.2024.101084_bib0034","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S2213-2600(21)00125-9","article-title":"Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuroinflammation, and neuroimmune responses","volume":"9","author":"Song","year":"2021","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.imr.2024.101084_bib0035","unstructured":"World Health Organization. WHO Director-General's opening remarks at the media briefing. Accessed 17 February 2023. https:\/\/www.who.int\/director-general\/speeches\/detail\/who-director-general-s-opening-remarks-at-the-media-briefing, 5-may-2023."}],"container-title":["Integrative Medicine Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213422024000647?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213422024000647?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T20:11:19Z","timestamp":1737663079000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213422024000647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S2213422024000647"],"URL":"https:\/\/doi.org\/10.1016\/j.imr.2024.101084","relation":{},"ISSN":["2213-4220"],"issn-type":[{"value":"2213-4220","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term follow-up of the treatment for severe COVID-19 with qigong exercise and acupressure: A randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Integrative Medicine Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.imr.2024.101084","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Korea Institute of Oriental Medicine. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101084"}}