{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:41:15Z","timestamp":1770748875375,"version":"3.50.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T00:00:00Z","timestamp":1655942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection Prevention in Practice"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.infpip.2022.100227","type":"journal-article","created":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T16:53:52Z","timestamp":1656435232000},"page":"100227","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Multiplex PCR in the empirical antibiotic treatment of patients with SARS-CoV-2 and bacterial respiratory superinfection"],"prefix":"10.1016","volume":"4","author":[{"given":"V.","family":"Paz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.L.","family":"D'Agostino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Garibaldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Orellana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Paniagua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Santill\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.infpip.2022.100227_bib1","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.cmi.2020.12.018","article-title":"Antibiotic prescribing in patients with COVID-19: rapid review and meta-analysis","volume":"27","author":"Langford","year":"2021","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.infpip.2022.100227_bib2","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s11908-020-00734-x","article-title":"Antimicrobial stewardship at the core of COVID-19 response efforts: implications for sustaining and building programs","volume":"22","author":"Mazdeyasna","year":"2020","journal-title":"Curr Infect Dis Rep"},{"key":"10.1016\/j.infpip.2022.100227_bib3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13756-021-00893-z","article-title":"Antimicrobial multidrug resistance in the era of COVID-19: a forgotten plight?","volume":"10","author":"Pelfrene","year":"2021","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.infpip.2022.100227_bib4","unstructured":"Programa Nacional VIHDA. Manual de Viligilancia de Infecciones Asociadas al Cuidado de la Salud en Argentina. Available at: http:\/\/codeinep.org\/wp-content\/uploads\/2017\/11\/Manual-de-VIGILANCIA-VIHDA-2015.pdf [last accessed March 2022]."},{"key":"10.1016\/j.infpip.2022.100227_bib5","first-page":"245","article-title":"Neumon\u00eda adquirida de la comunidad en adultos. Recomendaciones sobre su atenci\u00f3n","volume":"75","author":"Lopardo","year":"2015","journal-title":"Medicina"},{"key":"10.1016\/j.infpip.2022.100227_bib6","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/j.cmi.2020.07.016","article-title":"Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis","volume":"26","author":"Langford","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.infpip.2022.100227_bib7","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1186\/s13054-020-03013-2","article-title":"The challenge of ventilator-associated pneumonia diagnosis in COVID-19 patients","volume":"24","author":"Fran\u00e7ois","year":"2020","journal-title":"Crit Care"},{"key":"10.1016\/j.infpip.2022.100227_bib8","first-page":"1","article-title":"Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unit","volume":"17","author":"Maataoui","year":"2021","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.infpip.2022.100227_bib9","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/S2666-5247(20)30009-4","article-title":"Co-infections: potentially lethal and unexplored in COVID-19","volume":"1","author":"Cox","year":"2020","journal-title":"Lancet Microbe"},{"key":"10.1016\/j.infpip.2022.100227_bib10","doi-asserted-by":"crossref","first-page":"ofaa484","DOI":"10.1093\/ofid\/ofaa484","article-title":"Assessment of respiratory bacterial coinfection among severe acute respiratory s\u00edndrome coronavirus 2-positive patients hospitalized in intensive care units using conventional culture and BioFire, FilmArray pneumonia panel plus assay","volume":"7","author":"Kolenda","year":"2020","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.infpip.2022.100227_bib11","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s00134-020-05967-x","article-title":"Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists","volume":"46","author":"Bouadma","year":"2020","journal-title":"Intensive Care"},{"key":"10.1016\/j.infpip.2022.100227_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.mimet.2021.106259","article-title":"Respiratory bacterial co-infections in intensive care unit-hospitalized COVID-19 patients: conventional culture vs BioFire FilmArray pneumonia plus panel","volume":"186","author":"Foschi","year":"2021","journal-title":"J\u00a0Microbiol Methods"},{"key":"10.1016\/j.infpip.2022.100227_bib13","series-title":"Ventilator-associated pneumonia in the SARS coronavirus 2 (SARS-CoV-2) age: a new entity? 31st European Congress of Clinical Microbiology and Infectious Diseases, Vienna, Austria","first-page":"9","author":"Paz","year":"2021"},{"key":"10.1016\/j.infpip.2022.100227_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.diagmicrobio.2020.115183","article-title":"Performance of a multiplex polymerase chain reaction panel for identifying bacterial pathogens causing pneumonia in critically ill patient with COVID-19","volume":"99","author":"Cam\u00e9l\u00e9na","year":"2021","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.infpip.2022.100227_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.diagmicrobio.2020.115236","article-title":"Laboratory evaluation of the BioFire FilmArray Pneumonia plus panel compared to conventional methods for the identification of bacteria in lower respiratory tract specimen: a prospective cross-sectional study from South Africa","volume":"99","author":"Mitton","year":"2021","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.infpip.2022.100227_bib16","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1186\/s13054-020-03114-y","article-title":"Multicenter evaluation of syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia","volume":"24","author":"Monard","year":"2020","journal-title":"Crit Care"},{"key":"10.1016\/j.infpip.2022.100227_bib17","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1186\/s13054-020-03067-2","article-title":"Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia","volume":"24","author":"Peiffer-Smadja","year":"2020","journal-title":"Crit Care"},{"key":"10.1016\/j.infpip.2022.100227_bib18","doi-asserted-by":"crossref","DOI":"10.1136\/thoraxjnl-2021-216990","article-title":"Multicentre evaluation of two multiplex PCR platforms for the rapid microbiological investigation of nosocomial pneumonia in UK ICUs: the INHALE WP1 study","author":"Enne","year":"2022","journal-title":"Thorax"},{"key":"10.1016\/j.infpip.2022.100227_bib19","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.jmii.2019.10.009","article-title":"Performance of a multiplex PCR pneumonia panel for the identification of respiratory pathogens and the main determinants of resistance from the lower respiratory tract specimens of adult patients in intensive care units","volume":"52","author":"Lee","year":"2019","journal-title":"J\u00a0Microbiol Immunol Infect"},{"key":"10.1016\/j.infpip.2022.100227_bib20","doi-asserted-by":"crossref","first-page":"e00135-20","DOI":"10.1128\/JCM.00135-20","article-title":"Practical comparison of the BioFire FilmArray Pneumonia panel to routine diagnostic methods and potential impact on antimicrobial stewardship in adult hospitalized patients with lower respiratory tract infections","volume":"58","author":"Buchan","year":"2020","journal-title":"J\u00a0Clin Microbiol"}],"container-title":["Infection Prevention in Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590088922000282?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590088922000282?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T01:32:02Z","timestamp":1762911122000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590088922000282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S2590088922000282"],"URL":"https:\/\/doi.org\/10.1016\/j.infpip.2022.100227","relation":{},"ISSN":["2590-0889"],"issn-type":[{"value":"2590-0889","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiplex PCR in the empirical antibiotic treatment of patients with SARS-CoV-2 and bacterial respiratory superinfection","name":"articletitle","label":"Article Title"},{"value":"Infection Prevention in Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.infpip.2022.100227","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society.","name":"copyright","label":"Copyright"}],"article-number":"100227"}}