{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T18:03:42Z","timestamp":1780509822799,"version":"3.54.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection Prevention in Practice"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.infpip.2026.100533","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T20:33:04Z","timestamp":1774038784000},"page":"100533","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical characteristics and mortality risk factors in enterococcal bloodstream infections: a 9-year retrospective cohort study in Japan"],"prefix":"10.1016","volume":"8","author":[{"given":"Hitoshi","family":"Tsukamoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Suehiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Higashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyohei","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukio","family":"Hida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ippei","family":"Sakamaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.infpip.2026.100533_bib1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1017\/ice.2016.254","article-title":"Incidence and outcomes associated with infections caused by vancomycin-resistant enterococci in the United States: systematic literature review and meta-analysis","volume":"38","author":"Chiang","year":"2017","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.infpip.2026.100533_bib2","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1111\/1469-0691.12083","article-title":"A multicentre analysis of epidemiology of the nosocomial bloodstream infections in Japanese university hospitals","volume":"19","author":"Nagao","year":"2013","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.infpip.2026.100533_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.1075185","article-title":"A multicenter investigation of 2,773 cases of bloodstream infections based on China Antimicrobial Surveillance Network (CHINET)","volume":"12","author":"Hu","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.infpip.2026.100533_bib4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/23744235.2022.2131901","article-title":"Increasing trend in enterococcal bacteraemia and vancomycin resistance in a tertiary care hospital in Croatia, 2017\u20132021","volume":"55","author":"Todori\u0107","year":"2023","journal-title":"Inf Disp"},{"key":"10.1016\/j.infpip.2026.100533_bib5","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2020.25.35.1900575","article-title":"Increasing proportion of vancomycin-resistance among enterococcal bacteraemias in Switzerland: a 6-year nation-wide surveillance, 2013 to 2018","volume":"25","author":"Piezzi","year":"2020","journal-title":"Euro Surveill"},{"key":"10.1016\/j.infpip.2026.100533_bib6","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1093\/jac\/dkw319","article-title":"Longitudinal (2001\u201314) analysis of Enterococci and VRE causing invasive infections in European and US hospitals, including a contemporary (2010\u201313) analysis of oritavancin in vitro potency","volume":"71","author":"Mendes","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.infpip.2026.100533_bib7","unstructured":"Ministry of Health, Labour and Welfare, Japan Nosocomial Infections Surveillance (JANIS). Available at:. https:\/\/janis.mhlw.go.jp\/english\/index.asp."},{"key":"10.1016\/j.infpip.2026.100533_bib8","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3390\/antibiotics10101189","article-title":"A view on 20 years of antimicrobial resistance in Japan by two national surveillance systems: the National Epidemiological Surveillance of Infectious Diseases and Japan Nosocomial Infections Surveillance","volume":"10","author":"Suzuki","year":"2021","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.infpip.2026.100533_bib9","doi-asserted-by":"crossref","first-page":"601","DOI":"10.3390\/antibiotics13070601","article-title":"Risk factors for 30-day mortality in nosocomial enterococcal bloodstream infections","volume":"13","author":"Zerbato","year":"2024","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.infpip.2026.100533_bib10","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s13756-018-0419-9","article-title":"The importance of adjusting for Enterococcus species when assessing the burden of vancomycin resistance: a cohort study including over 1000 cases of enterococcal bloodstream infections","volume":"7","author":"Kramer","year":"2018","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.infpip.2026.100533_bib11","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jiac.2017.03.009","article-title":"A 10-year profile of enterococcal bloodstream infections at a tertiary-care hospital in Japan","volume":"23","author":"Suzuki","year":"2017","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.infpip.2026.100533_bib12","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1007\/s15010-024-02249-2","article-title":"Epidemiological trends and susceptibility patterns of bloodstream infections caused by Enterococcus spp. in six German university hospitals: a prospectively evaluated multicentre cohort study from 2016 to 2020 of the R-Net Study Group","volume":"52","author":"Hornuss","year":"2024","journal-title":"Infection"},{"key":"10.1016\/j.infpip.2026.100533_bib13","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1080\/22221751.2020.1769500","article-title":"The ongoing challenge of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis in Europe: an epidemiological analysis of bloodstream infections","volume":"9","author":"Ayobami","year":"2020","journal-title":"Emerg Microb Infect"},{"key":"10.1016\/j.infpip.2026.100533_bib14","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1017\/ice.2015.228","article-title":"VRE and VSE bacteremia outcomes in the era of effective VRE therapy: a systematic review and meta-analysis","volume":"37","author":"Prematunge","year":"2016","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.infpip.2026.100533_bib15","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1007\/s10096-024-04917-5","article-title":"Clinical characteristics, predisposing factors and outcomes for Enterococcus faecalis versus Enterococcus faecium bloodstream infections: a prospective multicentre cohort study","volume":"43","author":"Scharloo","year":"2024","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.infpip.2026.100533_bib16","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3947\/ic.2022.0069","article-title":"Bloodstream infections in patients with hematologic diseases: causative organisms and factors associated with resistance","volume":"54","author":"Choi","year":"2022","journal-title":"Infect Chemother"},{"key":"10.1016\/j.infpip.2026.100533_bib17","first-page":"277","article-title":"Antimicrobial resistance and biofilm formation in Enterococcus spp. isolated from humans and turkeys in Poland, Microb","volume":"25","author":"Wo\u017aniak-Biel","year":"2019","journal-title":"Drug Res"},{"key":"10.1016\/j.infpip.2026.100533_bib18","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s13756-020-00770-1","article-title":"Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics","volume":"9","author":"Zhou","year":"2020","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.infpip.2026.100533_bib19","first-page":"124","article-title":"Vancomycin-resistant enterococcal bacteremia: comparison of clinical features and outcome between Enterococcus faecium and Enterococcus faecalis","volume":"41","author":"Chou","year":"2008","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.infpip.2026.100533_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0074734","article-title":"Increase in bloodstream infection due to vancomycin-susceptible Enterococcus faecium in cancer patients: risk factors, molecular epidemiology and outcomes","volume":"8","author":"Gudiol","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.infpip.2026.100533_bib21","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1086\/427512","article-title":"Impact of vancomycin resistance on mortality among patients with neutropenia and enterococcal bloodstream infection","volume":"191","author":"DiazGranados","year":"2005","journal-title":"J Infect Dis"},{"key":"10.1016\/j.infpip.2026.100533_bib22","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jiac.2018.01.001","article-title":"Clinical management of non-faecium non-faecalis vancomycin-resistant enterococci infection: focus on Enterococcus gallinarum and Enterococcus casseliflavus\/flavescens","volume":"24","author":"Monticelli","year":"2018","journal-title":"J Infect Chemother"}],"container-title":["Infection Prevention in Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590088926000272?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590088926000272?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:18:40Z","timestamp":1780507120000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590088926000272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S2590088926000272"],"URL":"https:\/\/doi.org\/10.1016\/j.infpip.2026.100533","relation":{},"ISSN":["2590-0889"],"issn-type":[{"value":"2590-0889","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical characteristics and mortality risk factors in enterococcal bloodstream infections: a 9-year retrospective cohort study in Japan","name":"articletitle","label":"Article Title"},{"value":"Infection Prevention in Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.infpip.2026.100533","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society.","name":"copyright","label":"Copyright"}],"article-number":"100533"}}