{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:50:44Z","timestamp":1762458644338},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Injury"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1016\/j.injury.2008.06.005","type":"journal-article","created":{"date-parts":[[2008,8,7]],"date-time":"2008-08-07T04:37:26Z","timestamp":1218083846000},"page":"83-89","source":"Crossref","is-referenced-by-count":6,"special_numbering":"S","title":["Free vascularised tissue transfer and brachytherapy for soft-tissue sarcomas of the extremities"],"prefix":"10.1016","volume":"39","author":[{"given":"Panayiotis J.","family":"Papagelopoulos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas F.","family":"Mavrogenis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios P.","family":"Mastorakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Vlastou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Vrouvas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panayotis N.","family":"Soucacos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.injury.2008.06.005_bib1","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.ijrobp.2003.10.048","article-title":"Soft tissue sarcomas treated with postoperative external beam radiotherapy with and without low-dose-rate brachytherapy","volume":"59","author":"Andrews","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.injury.2008.06.005_bib2","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1097\/00000658-199211000-00011","article-title":"Vascularized tissue transfer for closure of irradiated wounds after soft tissue sarcoma resection","volume":"216","author":"Barwick","year":"1992","journal-title":"Ann Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib3","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/00003086-200206000-00024","article-title":"Sciatic nerve resection: is that truly an indication for amputation?","volume":"399","author":"Bickels","year":"2002","journal-title":"Clin Orthop"},{"key":"10.1016\/j.injury.2008.06.005_bib4","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s007760070005","article-title":"Limb salvage in lower extremity sarcomas and technical details about vascular reconstruction","volume":"5","author":"Bonardelli","year":"2000","journal-title":"J Orthop Sci"},{"key":"10.1016\/j.injury.2008.06.005_bib5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/01.cco.0000166652.15546.4f","article-title":"Adjuvant chemotherapy for soft tissue sarcoma","volume":"17","author":"Casali","year":"2005","journal-title":"Curr Opin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib6","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S1470-2045(03)01113-6","article-title":"Amputation for soft-tissue sarcoma","volume":"4","author":"Clark","year":"2003","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib7","first-page":"625","article-title":"Soft-tissue lumps and bumps","volume":"54","author":"Damron","year":"2004","journal-title":"AAOS Instruct Course Lect"},{"key":"10.1016\/j.injury.2008.06.005_bib8","doi-asserted-by":"crossref","first-page":"4472","DOI":"10.1200\/JCO.2002.03.084","article-title":"Function and health status outcomes in a randomized trial comparing preoperative and postoperative radiotherapy in extremity soft tissue sarcoma","volume":"20","author":"Davis","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib9","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/(SICI)1096-9098(200004)73:4<206::AID-JSO4>3.0.CO;2-5","article-title":"Predictors of functional outcomes following limb salvage surgery for lower extremity soft tissue sarcoma","volume":"73","author":"Davis","year":"2000","journal-title":"J Surg Oncol"},{"issue":"4","key":"10.1016\/j.injury.2008.06.005_bib10","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/S0360-3016(03)00186-X","article-title":"Neoadjuvant chemotherapy and radiotherapy for large extremity soft-tissue sarcomas","volume":"56","author":"DeLaney","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.injury.2008.06.005_bib11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1055\/s-2005-864840","article-title":"Arterialized venous flow-through flap for simultaneous reconstruction of a radial artery defect and palmar forearm soft-tissue loss from sarcoma resection","volume":"21","author":"Deune","year":"2005","journal-title":"J Reconstr Microsurg"},{"issue":"3","key":"10.1016\/j.injury.2008.06.005_bib12","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1245\/ASO.2005.03.045","article-title":"Prognostic factors for survival in patients with locally recurrent extremity soft tissue sarcomas","volume":"12","author":"Eilber","year":"2005","journal-title":"Ann Surg Oncol"},{"issue":"2","key":"10.1016\/j.injury.2008.06.005_bib13","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/01.SLA.0000048448.56448.70","article-title":"High grade extremity soft tissue sarcomas: factors predictive of local recurrence and its effect on morbidity and mortality","volume":"237","author":"Eilber","year":"2003","journal-title":"Ann Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/00000637-199708000-00006","article-title":"Adjuvant therapy: the effects on microvascular lower extremity reconstruction","volume":"39","author":"Evans","year":"1997","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib15","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/01.cco.0000166651.38417.c8","article-title":"Surgical considerations for management of distal extremity soft tissue sarcomas","volume":"17","author":"Ferguson","year":"2005","journal-title":"Curr Opin Oncol"},{"issue":"12","key":"10.1016\/j.injury.2008.06.005_bib16","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1245\/ASO.2005.06.036","article-title":"The surgical and functional outcome of limb-salvage surgery with vascular reconstruction for soft tissue sarcoma of the extremity","volume":"12","author":"Ghert","year":"2005","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib17","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/S0959-8049(01)00083-1","article-title":"A randomized phase II study on neo-adjuvant chemotherapy for \u201chigh-risk\u201d adult soft-tissue sarcoma","volume":"37","author":"Gortzak","year":"2001","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.injury.2008.06.005_bib18","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1200\/JCO.2005.04.160","article-title":"Status of surgical margins and prognosis in adult soft tissue sarcomas of the extremities: a series of patients treated at a single institution","volume":"23","author":"Gronchi","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib19","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/jso.20485","article-title":"Lower extremity reconstruction","volume":"94","author":"Heller","year":"2006","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib20","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s002689900056","article-title":"Major vessel resection during limb-preserving surgery for soft tissue sarcomas","volume":"20","author":"Karakousis","year":"1996","journal-title":"World J Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib21","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1200\/JCO.2005.02.5577","article-title":"Phase II study of neoadjuvant chemotherapy and radiation therapy in the management of high-risk, high-grade soft tissue sarcomas of the extremities and body wall: Radiation Therapy Oncology Group Trial 9514.","volume":"24","author":"Kraybill","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib22","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/00003086-200106000-00028","article-title":"Limb salvage surgery with vascular reconstruction","volume":"387","author":"Leggon","year":"2001","journal-title":"Clin Orthop"},{"key":"10.1016\/j.injury.2008.06.005_bib23","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1067\/mva.2001.112799","article-title":"Sequelae after limb-sparing surgery with major vascular resection for tumor of the lower extremity","volume":"33","author":"Matsushita","year":"2001","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib24","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/jso.20009","article-title":"The prognostic significance of margin width for extremity and trunk sarcoma","volume":"85","author":"McKee","year":"2004","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib25","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1002\/cncr.10794","article-title":"Radiographic response to neoadjuvant chemotherapy is a predictor of local control and survival in soft tissue sarcomas","volume":"95","author":"Meric","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.injury.2008.06.005_bib26","series-title":"Presented at the 7th EFORT Congress","article-title":"Post-operative brachytherapy and free vascularized muscle flap transfer in the management of soft tissue sarcomas of the extremities","author":"Papagelopoulos","year":"2007"},{"key":"10.1016\/j.injury.2008.06.005_bib27","series-title":"Presented at the 75th AAOS Annual Meeting","article-title":"Post-operative brachytherapy and free vascularized muscle flap transfer in the management of soft tissue sarcomas of the extremities","author":"Papagelopoulos","year":"2008"},{"key":"10.1016\/j.injury.2008.06.005_bib28","first-page":"26","article-title":"Re-resection with brachytherapy for locally recurrent soft tissue sarcoma arising in a previously radiated field","volume":"5","author":"Pearlstone","year":"1999","journal-title":"Cancer J Sci Am"},{"key":"10.1016\/j.injury.2008.06.005_bib29","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1097\/00006534-199404001-00012","article-title":"Wound-healing complications after soft-tissue sarcoma surgery","volume":"93","author":"Peat","year":"1994","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib30","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1200\/JCO.1996.14.3.859","article-title":"Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma","volume":"14","author":"Pisters","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib31","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1200\/JCO.2006.09.8525","article-title":"Evidence-based recommendations for local therapy for soft tissue sarcomas","volume":"25","author":"Pisters","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib32","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1200\/JCO.2004.01.040","article-title":"Phase I trial of doxorubicin-based concurrent chemoradiation and surgical resection for localized extremity and body wall soft tissue sarcomas","volume":"22","author":"Pisters","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib33","doi-asserted-by":"crossref","first-page":"3481","DOI":"10.1200\/JCO.1997.15.12.3481","article-title":"Preoperative chemotherapy for stage IIIB extremity soft tissue sarcoma: long-term results from a single institution","volume":"15","author":"Pisters","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib34","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1002\/bjs.1800810817","article-title":"Management of soft tissue sarcoma","volume":"81","author":"Pitcher","year":"1994","journal-title":"Br J Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib35","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/00000658-198209000-00009","article-title":"The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy","volume":"196","author":"Rosenberg","year":"1982","journal-title":"Ann Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib36","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/jso.20235","article-title":"Extremity soft tissue sarcoma: evidence-based multidisciplinary management","volume":"90","author":"Scoggins","year":"2005","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib37","first-page":"540","article-title":"Prognostic factors for local control of sarcomas of the soft tissues managed by radiation and surgery","volume":"24","author":"Spiro","year":"1997","journal-title":"Semin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib38","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1097\/00000658-200203000-00015","article-title":"Analysis of the prognostic significance of microscopic margins in 2,084 localized primary adult soft tissue sarcomas","volume":"235","author":"Stojadinovic","year":"2002","journal-title":"Ann Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib39","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.hcl.2004.03.006","article-title":"Soft tissue reconstruction following tumor resection in the hand","volume":"20","author":"Talbot","year":"2004","journal-title":"Hand Clin"},{"key":"10.1016\/j.injury.2008.06.005_bib40","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1001\/archsurg.1983.01390080023007","article-title":"Metastatic patterns in soft-tissue sarcomas","volume":"118","author":"Vezeridis","year":"1983","journal-title":"Arch Surg"},{"key":"10.1016\/j.injury.2008.06.005_bib41","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1055\/s-2004-824885","article-title":"One-bone forearm reconstruction using vascularized fibular graft for massive forearm soft-tissue and bone defect: case report","volume":"20","author":"Wada","year":"2004","journal-title":"J Reconstr Microsurg"},{"key":"10.1016\/j.injury.2008.06.005_bib42","series-title":"Soft Tissue Tumors","author":"Weiss","year":"2001"},{"key":"10.1016\/j.injury.2008.06.005_bib43","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1097\/01.cco.0000161745.24887.82","article-title":"Preoperative vs postoperative radiation therapy for extremity soft tissue sarcoma: controversy and present management","volume":"17","author":"Wolfson","year":"2005","journal-title":"Curr Opin Oncol"},{"key":"10.1016\/j.injury.2008.06.005_bib44","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1200\/JCO.1998.16.1.197","article-title":"A randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity","volume":"16","author":"Yang","year":"1998","journal-title":"J Clin Oncol"}],"container-title":["Injury"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138308002635?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138308002635?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T01:05:59Z","timestamp":1557709559000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020138308002635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["S0020138308002635"],"URL":"https:\/\/doi.org\/10.1016\/j.injury.2008.06.005","relation":{},"ISSN":["0020-1383"],"issn-type":[{"value":"0020-1383","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}