{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T02:32:20Z","timestamp":1793845940682,"version":"4.6.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Injury"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.injury.2011.09.003","type":"journal-article","created":{"date-parts":[[2011,10,18]],"date-time":"2011-10-18T00:32:43Z","timestamp":1318897963000},"page":"772-778","source":"Crossref","is-referenced-by-count":123,"title":["Early soft tissue coverage and negative pressure wound therapy optimises patient outcomes in lower limb trauma"],"prefix":"10.1016","volume":"43","author":[{"given":"David Shi Hao","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Foti","family":"Sofiadellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Ashton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirstie","family":"MacGill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Webb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.injury.2011.09.003_bib0005","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/00003086-198309000-00008","article-title":"Primary versus delayed soft tissue coverage for severe open tibial fractures. A comparison of results","author":"Cierny","year":"1983","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.injury.2011.09.003_bib0010","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/00006534-198511000-00011","article-title":"Management of open tibial fractures","volume":"76","author":"Byrd","year":"1985","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0015","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0020-1383(97)00093-4","article-title":"Primary free-flap cover of open tibial fractures","volume":"28","author":"Sinclair","year":"1997","journal-title":"Injury"},{"key":"10.1016\/j.injury.2011.09.003_bib0020","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/0007-1226(92)90022-P","article-title":"Management of the soft tissues in open tibial fractures","volume":"45","author":"Small","year":"1992","journal-title":"Br J Plast Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0025","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1302\/0301-620X.82B7.10482","article-title":"Fix and flap: the radical orthopaedic and plastic treatment of severe open fractures of the tibia","volume":"82","author":"Gopal","year":"2000","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.injury.2011.09.003_bib0030","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s004020050346","article-title":"On the timing of soft-tissue reconstruction for open fractures of the lower leg","volume":"119","author":"Hertel","year":"1999","journal-title":"Arch Orthop Trauma Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0035","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1097\/PRS.0b013e31819f2b5e","article-title":"Soft-tissue defects and exposed hardware: a review of indications for soft-tissue reconstruction and hardware preservation","volume":"123","author":"Viol","year":"2009","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0040","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1097\/BOT.0b013e3181a2e2b6","article-title":"Negative pressure wound therapy after severe open fractures: a prospective randomized study","volume":"23","author":"Stannard","year":"2009","journal-title":"J Orthop Trauma"},{"key":"10.1016\/j.injury.2011.09.003_bib0130","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/BOT.0b013e3181ec45ba","article-title":"Negative pressure wound therapy reduces pseudomonas wound contamination more than Staphylococcus aureus","volume":"24","author":"Lalliss","year":"2010","journal-title":"J Orthop Trauma"},{"key":"10.1016\/j.injury.2011.09.003_bib0050","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/BOT.0b013e31802cbc54","article-title":"The use of negative-pressure wound therapy (NPWT) in the temporary treatment of soft-tissue injuries associated with high-energy open tibial shaft fractures","volume":"21","author":"Dedmond","year":"2007","journal-title":"J Orthop Trauma"},{"key":"10.1016\/j.injury.2011.09.003_bib0055","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/00006534-198609000-00001","article-title":"Early microsurgical reconstruction of complex trauma of the extremities","volume":"78","author":"Godina","year":"1986","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0060","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1097\/00005373-198908000-00005","article-title":"Reconstruction of the lower extremity with microvascular free flaps: a 10-year experience with 304 consecutive cases","volume":"29","author":"Khouri","year":"1989","journal-title":"J Trauma"},{"key":"10.1016\/j.injury.2011.09.003_bib0065","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/j.1445-2197.2007.04188.x","article-title":"Trauma centre experience: flap reconstruction of traumatic lower limb injuries","volume":"77","author":"Lo","year":"2007","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0070","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.bjps.2007.11.037","article-title":"Review of 197 consecutive free flap reconstructions in the lower extremity","volume":"61","author":"Wettstein","year":"2008","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0135","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/micr.20696","article-title":"Comparison of free anterolateral thigh flaps and free muscle-musculocutaneous flaps in soft tissue reconstruction of lower extremity","volume":"30","author":"Demirtas","year":"2010","journal-title":"Microsurgery"},{"key":"10.1016\/j.injury.2011.09.003_bib0080","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.2106\/00004623-199173090-00005","article-title":"The timing of flap coverage, bone-grafting, and intramedullary nailing in patients who have a fracture of the tibial shaft with extensive soft-tissue injury","volume":"73","author":"Fischer","year":"1991","journal-title":"J Bone Joint Surg Am"},{"issue":"Suppl. 1","key":"10.1016\/j.injury.2011.09.003_bib0085","first-page":"188","article-title":"Soft tissue management of open tibia fractures","volume":"62","author":"Yaremchuk","year":"1996","journal-title":"Acta Orthop Belg"},{"key":"10.1016\/j.injury.2011.09.003_bib0090","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1177\/1534734606295030","article-title":"Is there evidence-based guidance for timing of soft tissue coverage of grade III B tibia fractures?","volume":"5","author":"Breugem","year":"2006","journal-title":"Int J Low Extrem Wounds"},{"key":"10.1016\/j.injury.2011.09.003_bib0095","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.2106\/JBJS.F.00146","article-title":"Trends in the management of open fractures. A critical analysis","volume":"88","author":"Okike","year":"2006","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.injury.2011.09.003_bib0100","doi-asserted-by":"crossref","first-page":"801","DOI":"10.2106\/00004623-198769060-00002","article-title":"Severe open fractures of the tibia","volume":"69","author":"Caudle","year":"1987","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.injury.2011.09.003_bib0105","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/S0736-0266(02)00072-4","article-title":"Effect of repeated irrigation and debridement on fracture healing in an animal model","volume":"20","author":"Park","year":"2002","journal-title":"J Orthop Res"},{"key":"10.1016\/j.injury.2011.09.003_bib0110","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1097\/01.prs.0000305536.09242.a6","article-title":"Routine use of wound vacuum-assisted closure does not allow coverage delay for open tibia fractures","volume":"121","author":"Bhattacharyya","year":"2008","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0115","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/01.sap.0000111861.75927.4d","article-title":"Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bacterial clearance?","volume":"52","author":"Weed","year":"2004","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.injury.2011.09.003_bib0120","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1067-1927.2004.12105.x","article-title":"Bacterial load in relation to vacuum-assisted closure wound therapy: a prospective randomized trial","volume":"12","author":"Moues","year":"2004","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.injury.2011.09.003_bib0125","series-title":"Standards for the management of Open Fractures of the Lower Limb","author":"Nanchahal","year":"2009"}],"container-title":["Injury"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138311004463?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138311004463?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T20:27:10Z","timestamp":1713040030000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020138311004463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0020138311004463"],"URL":"https:\/\/doi.org\/10.1016\/j.injury.2011.09.003","relation":{},"ISSN":["0020-1383"],"issn-type":[{"value":"0020-1383","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}