{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:39:57Z","timestamp":1774611597843,"version":"3.50.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","injuryjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Injury"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.injury.2016.05.031","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T14:13:10Z","timestamp":1464099190000},"page":"1913-1918","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Randomized, controlled trial of povidone-iodine to reduce simple traumatic wound infections in the emergency department"],"prefix":"10.1016","volume":"47","author":[{"given":"Hamed Basir","family":"Ghafouri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morteza","family":"Zare","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azam","family":"Bazrafshan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niloofar","family":"Abazarian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tayeb","family":"Ramim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.injury.2016.05.031_bib0005","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0733-8627(02)00087-1","article-title":"Management of lacerations in the emergency department","volume":"21","author":"Capellan","year":"2003","journal-title":"Emerg Med Clin North Am"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0010","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/S0196-0644(99)70131-9","article-title":"Laceration management","volume":"34","author":"Hollander","year":"1999","journal-title":"Ann Emerg Med"},{"issue":"7","key":"10.1016\/j.injury.2016.05.031_bib0015","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1111\/j.1553-2712.2001.tb00190.x","article-title":"Risk factors for infection in patients with traumatic lacerations","volume":"8","author":"Hollander","year":"2001","journal-title":"Acad Emerg Med"},{"issue":"2","key":"10.1016\/j.injury.2016.05.031_bib0020","first-page":"51","article-title":"Wound cleansing: which solution what technique?","volume":"9","author":"Fernandez","year":"2001","journal-title":"Wound Clean"},{"issue":"5","key":"10.1016\/j.injury.2016.05.031_bib0025","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1553-2712.2007.tb01798.x","article-title":"A multicenter comparison of tap water versus sterile saline for wound irrigation","volume":"14","author":"Moscati","year":"2007","journal-title":"Acad Emerg Med"},{"issue":"6","key":"10.1016\/j.injury.2016.05.031_bib0030","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/j.1742-481X.2009.00639.x","article-title":"Wound cleansing, topical antiseptics and wound healing","volume":"6","author":"Atiyeh","year":"2009","journal-title":"Int Wound J"},{"issue":"4","key":"10.1016\/j.injury.2016.05.031_bib0035","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S0965-206X(06)64002-3","article-title":"Antiseptics, iodine, povidone iodine and traumatic wound cleansing","volume":"16","author":"Khan","year":"2006","journal-title":"J Tissue Viability"},{"key":"10.1016\/j.injury.2016.05.031_bib0040","first-page":"18","article-title":"Should I prescribe a topical antiseptic cream instead of a topical antibiotic for minor skin infections?","volume":"68","author":"The Best Practice Advocacy Centre New Zealand","year":"2015","journal-title":"Best Pract J"},{"key":"10.1016\/j.injury.2016.05.031_bib0045","series-title":"Wound management for the advanced practitioner","author":"Swanson","year":"2014"},{"key":"10.1016\/j.injury.2016.05.031_bib0050","unstructured":"Knobler SL, Mahmoud AAF, Pray LA. Department Of Health And Human Services: Food and Drug Administration [Docket No. 01N\u00e2\u20ac0494] 2002."},{"issue":"6","key":"10.1016\/j.injury.2016.05.031_bib0055","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/00005373-199106000-00007","article-title":"The cytotoxic effects of commonly used topical antimicrobial agents on human fibroblasts and keratinocytes","volume":"31","author":"Cooper","year":"1991","journal-title":"J Trauma Acute Care Surg"},{"issue":"6","key":"10.1016\/j.injury.2016.05.031_bib0060","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/0305-4179(92)90180-3","article-title":"Cytotoxicity evaluation of antiseptics and antibiotics on cultured human fibroblasts and keratinocytes","volume":"18","author":"Damour","year":"1992","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0065","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0022-4804(89)90069-3","article-title":"In vitro toxicity of topical antimicrobial agents to human fibroblasts","volume":"46","author":"McCauley","year":"1989","journal-title":"J Surg Res"},{"issue":"1","key":"10.1016\/j.injury.2016.05.031_bib0070","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/TA.0b013e31818b146d","article-title":"Mechanisms of delayed wound healing by commonly used antiseptics","volume":"66","author":"Thomas","year":"2009","journal-title":"J Trauma Acute Care Surg"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0075","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1097\/00005373-199309000-00034","article-title":"The cytotoxic effects of commonly used topical antimicrobial agents on human fibroblasts and keratinocytes","volume":"35","author":"Welch","year":"1993","journal-title":"J Trauma"},{"issue":"7","key":"10.1016\/j.injury.2016.05.031_bib0080","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/00129334-200509000-00011","article-title":"A toxicity index of skin and wound cleansers used on in vitro fibroblasts and keratinocytes","volume":"18","author":"Wilson","year":"2005","journal-title":"Adv Skin Wound Care"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0085","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.suc.2009.03.005","article-title":"Management of acute wounds","volume":"89","author":"Lee","year":"2009","journal-title":"Surg Clin North Am"},{"key":"10.1016\/j.injury.2016.05.031_bib0090","article-title":"Tintinalli's Emergency Medicine: A Comprehensive Study Guide","author":"Tintinalli","year":"2015"},{"key":"10.1016\/j.injury.2016.05.031_bib0095","series-title":"Surgical Site Infection (SSI) Event","first-page":"1","author":"U.S. Centers for Disease Control and Prevention","year":"2016"},{"issue":"1","key":"10.1016\/j.injury.2016.05.031_bib0100","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.emc.2007.01.007","article-title":"Use of appropriate antimicrobials in wound management","volume":"25","author":"Nakamura","year":"2007","journal-title":"Emerg Med Clin North Am"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0105","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S0266-7681(85)80064-4","article-title":"A prospective trial of prophylactic povidone iodine in lacerations of the hand","volume":"10","author":"Roberts","year":"1985","journal-title":"J Hand Surg (Br Eur Vol)"},{"issue":"1","key":"10.1016\/j.injury.2016.05.031_bib0110","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1056\/NEJMoa0810988","article-title":"Chlorhexidine & alcohol versus povidone-iodine for surgical-site antisepsis","volume":"362","author":"Darouiche","year":"2010","journal-title":"New Engl J Med"},{"issue":"11","key":"10.1016\/j.injury.2016.05.031_bib0115","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1002\/bjs.7214","article-title":"Systematic review and meta\u2010analysis of preoperative antisepsis with chlorhexidine versus povidone\u2013iodine in clean\u2010contaminated surgery","volume":"97","author":"Noorani","year":"2010","journal-title":"Br J Surg"},{"issue":"6","key":"10.1016\/j.injury.2016.05.031_bib0120","first-page":"473","article-title":"The efficacy and risks of using povidone-iodine irrigation to prevent surgical site infection: an evidence-based review","volume":"50","author":"Chundamala","year":"2007","journal-title":"Can J Surg"},{"issue":"11","key":"10.1016\/j.injury.2016.05.031_bib0125","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1002\/bjs.7212","article-title":"Meta\u2010analysis of intraoperative povidone\u2013iodine application to prevent surgical\u2010site infection","volume":"97","author":"Fournel","year":"2010","journal-title":"Br J Surg"},{"issue":"10","key":"10.1016\/j.injury.2016.05.031_bib0130","first-page":"964","article-title":"Effects of preoperative skin preparation on postoperative wound infection rates a prospective study of 3 skin preparation protocols","volume":"30","author":"Swenson","year":"2009","journal-title":"Infect Control"},{"issue":"4","key":"10.1016\/j.injury.2016.05.031_bib0135","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/0195-6701(83)90014-2","article-title":"Antiseptics and the casualty wound","volume":"4","author":"Stringer","year":"1983","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.injury.2016.05.031_bib0140","first-page":"CD003861","article-title":"Water for wound cleansing","volume":"1","author":"Fernandez","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0145","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/102490791402100303","article-title":"A pilot study on the repair of contaminated traumatic wounds in the emergency department using sterile versus non-sterile gloves","volume":"21","author":"Ghafouri","year":"2014","journal-title":"Hong Kong J Emerg Med"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0150","doi-asserted-by":"crossref","first-page":"112","DOI":"10.12968\/jowc.2008.17.3.28668","article-title":"Should chlorhexidine gluconate be used in wound cleansing?","volume":"17","author":"Main","year":"2008","journal-title":"J Wound Care"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0155","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1159\/000210865","article-title":"Comparative study of antiseptic toxicity on basal keratinocytes, transformed human keratinocytes and fibroblasts","volume":"3","author":"Tatnall","year":"1990","journal-title":"Skin Pharmacol Physiol"},{"issue":"3","key":"10.1016\/j.injury.2016.05.031_bib0160","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/0002-9610(86)90477-0","article-title":"Chemical and microbiologic characteristics and toxicity of povidone-iodine solutions","volume":"151","author":"Zamora","year":"1986","journal-title":"Am J Surg"},{"issue":"1","key":"10.1016\/j.injury.2016.05.031_bib0165","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0002-9610(69)90089-0","article-title":"Studies in management of the contaminated wound: III. Assessment of the effectiveness of irrigation with antiseptic agents","volume":"118","author":"Edlich","year":"1969","journal-title":"Am J Surg"},{"issue":"4","key":"10.1016\/j.injury.2016.05.031_bib0170","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s12245-010-0217-5","article-title":"Acute wound management: revisiting the approach to assessment, irrigation, and closure considerations","volume":"3","author":"Nicks","year":"2010","journal-title":"Int J Emerg Med"},{"issue":"1","key":"10.1016\/j.injury.2016.05.031_bib0175","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.emc.2007.01.009","article-title":"Reducing risk in emergency department wound management","volume":"25","author":"Pfaff","year":"2007","journal-title":"Emerg Med Clin North Am"},{"issue":"2","key":"10.1016\/j.injury.2016.05.031_bib0180","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1136\/emermed-2012-202143","article-title":"Traumatic lacerations: what are the risks for infection and has the \u2018golden period\u2019 of laceration care disappeared?","volume":"31","author":"Quinn","year":"2014","journal-title":"Emerg Med J"},{"issue":"11","key":"10.1016\/j.injury.2016.05.031_bib0185","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1016\/j.injury.2012.02.018","article-title":"The impact of wound age on the infection rate of simple lacerations repaired in the emergency department","volume":"43","author":"Zehtabchi","year":"2012","journal-title":"Injury"}],"container-title":["Injury"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138316302030?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138316302030?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T15:28:38Z","timestamp":1567956518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020138316302030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0020138316302030"],"URL":"https:\/\/doi.org\/10.1016\/j.injury.2016.05.031","relation":{},"ISSN":["0020-1383"],"issn-type":[{"value":"0020-1383","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Randomized, controlled trial of povidone-iodine to reduce simple traumatic wound infections in the emergency department","name":"articletitle","label":"Article Title"},{"value":"Injury","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.injury.2016.05.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}