{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:25:38Z","timestamp":1789536338485,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","injuryjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Injury"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.injury.2017.08.005","type":"journal-article","created":{"date-parts":[[2017,8,4]],"date-time":"2017-08-04T15:31:56Z","timestamp":1501860716000},"page":"2230-2234","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Long-term follow-up evaluation of autologous chondrocyte implantation for symptomatic cartilage lesions of the knee: A single-centre prospective study"],"prefix":"10.1016","volume":"48","author":[{"given":"M.","family":"Berruto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Ferrua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Pasqualotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Uboldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Maione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Tradati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Usellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.injury.2017.08.005_bib0005","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1056\/NEJM199410063311401","article-title":"Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation","volume":"331","author":"Brittberg","year":"1994","journal-title":"N Engl J Med"},{"issue":"Suppl. 1","key":"10.1016\/j.injury.2017.08.005_bib0010","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1016\/j.injury.2008.01.040","article-title":"Autologous chondrocyte implantation\u2014technique and long-term follow-up","volume":"39","author":"Brittberg","year":"2008","journal-title":"Injury"},{"key":"10.1016\/j.injury.2017.08.005_bib0015","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1177\/0363546512453292","article-title":"Outcomes of autologous chondrocyte implantation in study of the treatment of articular repair (STAR) patients with osteochondritis dissecans","volume":"40","author":"Cole","year":"2012","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0020","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1177\/0363546510390476","article-title":"Clinical and magnetic resonance imaging-based outcomes to 5 years after matrix-induced autologous chondrocyte implantation to address articular cartilage defects in the knee","volume":"39","author":"Ebert","year":"2011","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0025","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1177\/0363546511415658","article-title":"Arthroscopic second-generation autologous chondrocyte implantation: a prospective 7-year follow-up study","volume":"39","author":"Filardo","year":"2011","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0030","doi-asserted-by":"crossref","first-page":"824","DOI":"10.2106\/JBJS.L.01695","article-title":"Autologous chondrocyte implantation in the knee: mid-term to long-term results","volume":"96","author":"Nawaz","year":"2014","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.injury.2017.08.005_bib0035","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1177\/0363546514548160","article-title":"Clinical and radiological long-term outcomes after matrix-induced autologous chondrocyte transplantation: a prospective follow-up at a minimum of 10 years","volume":"42","author":"Aldrian","year":"2014","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0040","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1302\/0301-620X.94B4.27495","article-title":"Minimum ten-year results of a prospective randomised study of autologous chondrocyte implantation versus mosaicplasty for symptomatic articular cartilage lesions of the knee","volume":"94","author":"Bentley","year":"2012","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.injury.2017.08.005_bib0045","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1007\/s00167-013-2778-3","article-title":"Ten-year clinical and radiographic outcomes after autologous chondrocyte implantation of femoral condyles","volume":"22","author":"Martin\u010di\u010d","year":"2014","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.injury.2017.08.005_bib0050","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1177\/0363546513506593","article-title":"Long-term outcomes after first-generation autologous chondrocyte implantation for cartilage defects of the knee","volume":"42","author":"Niemeyer","year":"2014","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0055","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1177\/0363546509357915","article-title":"Autologous chondrocyte implantation: a long-term follow-up","volume":"38","author":"Peterson","year":"2010","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0060","doi-asserted-by":"crossref","first-page":"3660","DOI":"10.1007\/s00167-014-3272-2","article-title":"Cartilage failures systematic literature review, critical survey analysis, and definition","volume":"23","author":"Filardo","year":"2015","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.injury.2017.08.005_bib0065","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s11999-013-3146-9","article-title":"The John Insall Award: a minimum 10-year outcome study of autologous chondrocyte implantation","volume":"472","author":"Minas","year":"2014","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.injury.2017.08.005_bib0070","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1177\/0363546509357915","article-title":"Autologous chondrocyte implantation: a long-term follow-up","volume":"38","author":"Peterson","year":"2010","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0075","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1016\/j.arthro.2012.05.883","article-title":"First-generation autologous chondrocyte implantation in patients with cartilage defects of the knee: 7 to 14 years\u2019 clinical and magnetic resonance imaging follow-up evaluation","volume":"28","author":"Moradi","year":"2012","journal-title":"Arthroscopy"},{"key":"10.1016\/j.injury.2017.08.005_bib0080","first-page":"207","article-title":"Autologous chondrocyte implantation: a comparison between an open periosteal-covered and an arthroscopic matrix-guided technique","volume":"73","author":"Manfredini","year":"2007","journal-title":"Acta Orthop Belg"},{"key":"10.1016\/j.injury.2017.08.005_bib0085","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1177\/0363546509351499","article-title":"Autologous chondrocyte implantation using the original periosteum-cover technique versus matrix-associated autologous chondrocyte implantation: a randomized clinical trial","volume":"38","author":"Zeifang","year":"2010","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0090","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1302\/0301-620X.87B5.15905","article-title":"Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a prospective, randomised study","volume":"87","author":"Bartlett","year":"2005","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.injury.2017.08.005_bib0095","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1007\/s00402-007-0413-9","article-title":"Autologous chondrocyte implantation for the treatment of retropatellar cartilage defects: clinical results referred to defect localisation","volume":"128","author":"Niemeyer","year":"2008","journal-title":"Arch Orthop Trauma Surg"},{"key":"10.1016\/j.injury.2017.08.005_bib0100","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1302\/0301-620X.88B1.16796","article-title":"Who is the ideal candidate for autologous chondrocyte implantation","volume":"88","author":"Krishnan","year":"2006","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.injury.2017.08.005_bib0105","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1177\/0363546513480780","article-title":"Does patient sex influence cartilage surgery outcome? Analysis of results at 5-year follow-up in a large cohort of patients treated with matrix-assisted autologous chondrocyte transplantation","volume":"41","author":"Filardo","year":"2013","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0110","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s00167-012-2280-3","article-title":"Is gender influencing the biomechanical results after autologous chondrocyte implantation","volume":"22","author":"Kreuz","year":"2014","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.injury.2017.08.005_bib0115","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1177\/0363546513518552","article-title":"Clinical profiling in cartilage regeneration: prognostic factors for midterm results of matrix-assisted autologous chondrocyte transplantation","volume":"42","author":"Filardo","year":"2014","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.injury.2017.08.005_bib0120","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00167-010-1054-z","article-title":"The basic science of the subchondral bone","volume":"18","author":"Madry","year":"2010","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.injury.2017.08.005_bib0125","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1007\/s00264-014-2368-0","article-title":"First-generation versus second-generation autologous chondrocyte implantation for treatment of cartilage defects of the knee: a matched-pair analysis on long-term clinical outcome","volume":"38","author":"Niemeyer","year":"2014","journal-title":"Int Orthop"}],"container-title":["Injury"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138317304825?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138317304825?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T15:21:13Z","timestamp":1535556073000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020138317304825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0020138317304825"],"URL":"https:\/\/doi.org\/10.1016\/j.injury.2017.08.005","relation":{},"ISSN":["0020-1383"],"issn-type":[{"value":"0020-1383","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term follow-up evaluation of autologous chondrocyte implantation for symptomatic cartilage lesions of the knee: A single-centre prospective study","name":"articletitle","label":"Article Title"},{"value":"Injury","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.injury.2017.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}