{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:24:00Z","timestamp":1786991040430,"version":"build-2736575974"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","injuryjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Injury"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.injury.2020.02.115","type":"journal-article","created":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T18:50:58Z","timestamp":1582570258000},"page":"830-839","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Antimicrobial silver-coating for locking plates shows uneventful osteotomy healing and good biocompatibility results of an experimental study in rabbits"],"prefix":"10.1016","volume":"51","author":[{"given":"Daniel","family":"Arens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8155-4202","authenticated-orcid":false,"given":"Stephan","family":"Zeiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Nehrbass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilabh","family":"Ranjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Paulin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Alt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.injury.2020.02.115_bib0001","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.2106\/JBJS.16.00240","article-title":"Global forum: the burden of bone and joint infections: a growing demand for more resources","volume":"99","author":"Malizos","year":"2017","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.injury.2020.02.115_bib0002","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.injury.2016.12.011","article-title":"Antimicrobial coated implants in trauma and orthopaedics-a clinical review and risk-benefit analysis","volume":"48","author":"Alt","year":"2017","journal-title":"Injury"},{"key":"10.1016\/j.injury.2020.02.115_bib0003","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1016\/j.injury.2017.07.008","article-title":"Clinical experiences in the use of a gentamicin-coated titanium nail in tibia fractures","volume":"48","author":"Schmidmaier","year":"2017","journal-title":"Injury"},{"key":"10.1016\/j.injury.2020.02.115_bib0004","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1016\/j.injury.2015.09.028","article-title":"The use of gentamicin-coated nails in complex open tibia fracture and revision cases: a retrospective analysis of a single centre case series and review of the literature","volume":"46","author":"Metsemakers","year":"2015","journal-title":"Injury"},{"key":"10.1016\/j.injury.2020.02.115_bib0005","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1128\/AEM.02001-07","article-title":"Antibacterial activity and mechanism of action of the silver ion in staphylococcus aureus and escherichia coli","volume":"74","author":"Jung","year":"2008","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.injury.2020.02.115_bib0006","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S0966-842X(97)01033-0","article-title":"Bacterial resistance to aminoglycoside antibiotics","volume":"5","author":"Davies","year":"1997","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.injury.2020.02.115_bib0007","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0168-6445(03)00047-0","article-title":"Bacterial silver resistance: molecular biology and uses and misuses of silver compounds","volume":"27","author":"Silver","year":"2003","journal-title":"FEMS Microbiol Rev"},{"key":"10.1016\/j.injury.2020.02.115_bib0008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jhin.2004.11.014","article-title":"Bacterial resistance to silver in wound care","volume":"60","author":"Percival","year":"2005","journal-title":"J Hosp Infect"},{"issue":"2 Suppl","key":"10.1016\/j.injury.2020.02.115_bib0009","first-page":"252","article-title":"Antifungal properties of silver coating on tumour endoprostheses: an in vitro study","volume":"23","author":"D'Adamio","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci."},{"key":"10.1016\/j.injury.2020.02.115_bib0010","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9079041","article-title":"Silver-Coated Hip Megaprosthesis in oncological limb savage surgery","volume":"2016","author":"Donati","year":"2016","journal-title":"Biomed Res Int"},{"issue":"7","key":"10.1016\/j.injury.2020.02.115_bib0011","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1007\/s00132-019-03720-x","article-title":"Silver coating on tumour prostheses","volume":"48","author":"Friesenbichler","year":"2019","journal-title":"Orthopade"},{"key":"10.1016\/j.injury.2020.02.115_bib0012","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1302\/0301-620X.95B7.31124","article-title":"Argyria following the use of silver-coated megaprostheses: no association between the development of local argyria and elevated silver levels","volume":"95-B","author":"Glehr","year":"2013","journal-title":"Bone Joint J"},{"key":"10.1016\/j.injury.2020.02.115_bib0013","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1016\/j.biomaterials.2007.02.033","article-title":"Lack of toxicological sideeffects in silver-coated megaprostheses in humans","volume":"28","author":"Hardes","year":"2007","journal-title":"Biomaterials"},{"key":"10.1016\/j.injury.2020.02.115_bib0014","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/jso.21498","article-title":"Reduction of periprosthetic infection with silver-coated megaprostheses in patients with bone sarcoma","volume":"101","author":"Hardes","year":"2010","journal-title":"J Surg Oncol"},{"issue":"7","key":"10.1016\/j.injury.2020.02.115_bib0015","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1016\/j.arth.2017.02.054","article-title":"Silver-Coated megaprosthesis of the proximal tibia in patients with sarcoma","volume":"32","author":"Hardes","year":"2017","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.injury.2020.02.115_bib0016","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/763096","article-title":"Measurement of the silver ion concentration in wound fluids after implantation of silver-coated megaprostheses: correlation with the clinical outcome","volume":"2013","author":"Hussmann","year":"2013","journal-title":"Biomed Res Int"},{"issue":"4","key":"10.1016\/j.injury.2020.02.115_bib0017","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.ejso.2018.12.009","article-title":"Silver-coated (Agluna\u00ae) tumour prostheses can be a protective factor against infection in high risk failure patients","volume":"45","author":"Parry","year":"2019","journal-title":"Eur J Surg Oncol"},{"issue":"2","key":"10.1016\/j.injury.2020.02.115_bib0018","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s00264-016-3329-6","article-title":"Silver-coated endoprosthetic replacement of the proximal humerus in case of tumour-is there an increased risk of periprosthetic infection by using a trevira tube?","volume":"41","author":"Schmolders","year":"2017","journal-title":"Int Orthop."},{"issue":"2","key":"10.1016\/j.injury.2020.02.115_bib0019","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00402-016-2584-8","article-title":"Lower limb reconstruction in tumor patients using modular silver-coated megaprostheses with regard to perimegaprosthetic joint infection: a case series, including 100 patients and review of the literature","volume":"137","author":"Schmolders","year":"2017","journal-title":"Arch Orthop Trauma Surg"},{"issue":"47 Suppl","key":"10.1016\/j.injury.2020.02.115_bib0020","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/j.injury.2016.07.042","article-title":"Levels of silver ions in body fluids and clinical results in silver-coated megaprostheses after tumour, trauma or failed arthroplasty","volume":"4","author":"Scoccianti","year":"2016","journal-title":"Injury"},{"key":"10.1016\/j.injury.2020.02.115_bib0021","article-title":"Retrospective evaluation of the incidence of early periprosthetic infection with silver-treated endoprostheses in high-risk patients: case-control study","volume":"97","author":"Wafa","year":"2015","journal-title":"Bone Joint J"},{"key":"10.1016\/j.injury.2020.02.115_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.arth.2016.04.009","article-title":"Can a silver-Coated arthrodesis implant provide a viable alternative to above knee amputation in the unsalvageable, infected total knee arthroplasty?","author":"Wilding","year":"2016","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.injury.2020.02.115_bib0023","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1186\/s12891-017-1742-7","article-title":"Silver-coated modular megaendoprostheses in salvage revision arthroplasty after periimplant infection with extensive bone loss - a pilot study of 34 patients","volume":"18","author":"Zajonz","year":"2017","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.injury.2020.02.115_bib0024","doi-asserted-by":"crossref","first-page":"148","DOI":"10.22203\/eCM.v030a11","article-title":"A rabbit humerus model of plating and nailing osteosynthesis with and without staphylococcus aureus osteomyelitis","volume":"30","author":"Arens","year":"2015","journal-title":"Eur Cell Mater"},{"key":"10.1016\/j.injury.2020.02.115_bib0025","doi-asserted-by":"crossref","first-page":"5547","DOI":"10.1016\/j.biomaterials.2004.01.008","article-title":"Silver-coated megaendoprostheses in a rabbit model\u2013an analysis of the infection rate and toxicological side effects","volume":"2","author":"Gosheger","year":"2004","journal-title":"Biomaterials"},{"key":"10.1016\/j.injury.2020.02.115_bib0026","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0003-4878(95)00076-3","article-title":"The determination of silver in whole blood and its application to biological monitoring of occupationally exposed groups","volume":"40","author":"Armitage","year":"1996","journal-title":"Ann Occup Hyg"},{"key":"10.1016\/j.injury.2020.02.115_bib0027","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF00396598","article-title":"Biologic monitoring of workers exposed to silver","volume":"56","author":"DiVincenzo","year":"1985","journal-title":"Int Arch Occup Environ Health"}],"container-title":["Injury"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138320301893?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020138320301893?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T06:26:36Z","timestamp":1758090396000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020138320301893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S0020138320301893"],"URL":"https:\/\/doi.org\/10.1016\/j.injury.2020.02.115","relation":{},"ISSN":["0020-1383"],"issn-type":[{"value":"0020-1383","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antimicrobial silver-coating for locking plates shows uneventful osteotomy healing and good biocompatibility results of an experimental study in rabbits","name":"articletitle","label":"Article Title"},{"value":"Injury","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.injury.2020.02.115","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}