{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T10:34:32Z","timestamp":1770892472140,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["intestinalfailurejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intestinal Failure"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.intf.2026.100351","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T04:49:27Z","timestamp":1767934167000},"page":"100351","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Healthcare cost of home parenteral nutrition and intestinal transplantation for paediatric chronic intestinal failure in Singapore"],"prefix":"10.1016","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4777-0267","authenticated-orcid":false,"given":"Fang Kuan","family":"Chiou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye Xin","family":"Koh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4534-1426","authenticated-orcid":false,"given":"Lay Queen","family":"Ng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6924-5271","authenticated-orcid":false,"given":"Lynette","family":"Goh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yee","family":"Low","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pui Ling","family":"Wai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen Ling","family":"Ng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4315-4459","authenticated-orcid":false,"given":"Debra","family":"Sudan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prema Raj","family":"Jeyaraj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intf.2026.100351_bib1","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1053\/j.gastro.2005.12.002","article-title":"Causes and management of intestinal failure in children","volume":"130","author":"Goulet","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intf.2026.100351_bib2","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/MPG.0000000000001722","article-title":"Intestinal rehabilitation programs in the management of pediatric intestinal failure and short bowel syndrome","volume":"65","author":"Merritt","year":"2017","journal-title":"J Pedia Gastroenterol Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib3","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1056\/NEJMra1602650","article-title":"Pediatric intestinal failure","volume":"377","author":"Duggan","year":"2017","journal-title":"N Eng J Med"},{"key":"10.1016\/j.intf.2026.100351_bib4","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.clnu.2020.06.010","article-title":"The economic costs of home parenteral nutrition: systematic review of partial and full economic evaluation","volume":"40","author":"Arhip","year":"2021","journal-title":"Clin Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib5","first-page":"1226","article-title":"Cost-utility analysis of home parenteral nutrition","volume":"83","author":"Richards","year":"1996","journal-title":"Br J Surg"},{"key":"10.1016\/j.intf.2026.100351_bib6","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3350\/cmh.2014.20.4.327","article-title":"Cost-of-illness studies: concepts, scopes, and methods","volume":"20","author":"Jo","year":"2014","journal-title":"Clin Mol Hepatol"},{"key":"10.1016\/j.intf.2026.100351_bib7","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1111\/ajt.12812","article-title":"The current state of intestine transplantation: Indications, techniques, outcome and challenges","volume":"14","author":"Sudan","year":"2014","journal-title":"Am J Transpl"},{"key":"10.1016\/j.intf.2026.100351_bib8","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1097\/TP.0000000000003328","article-title":"Cost-effectiveness of intestinal transplantation compared to parenteral nutrition in adults","volume":"105","author":"Canovai","year":"2021","journal-title":"Transplantation"},{"key":"10.1016\/j.intf.2026.100351_bib9","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1136\/bmj.313.7052.275","article-title":"Guidelines for authors and peer reviewers of economic submissions to the BMJ. The BMJ Economic Evaluation Working Party","volume":"313","author":"Drummon","year":"1996","journal-title":"BMJ"},{"key":"10.1016\/j.intf.2026.100351_bib10","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S0140-6736(21)00252-X","article-title":"Singapore\u2019s health-care system: key features, challenges, and shifts","volume":"398","author":"Tan","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.intf.2026.100351_bib11","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1055\/a-2212-6874","article-title":"The development of the international intestinal failure registry and an overview of its results","volume":"34","author":"Avitzur","year":"2024","journal-title":"Eur J Pedia Surg"},{"key":"10.1016\/j.intf.2026.100351_bib12","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/TP.0000000000003065","article-title":"New insights into the indications for intestinal transplantation: Consensus in the year 2019","volume":"104","author":"Kaufman","year":"2020","journal-title":"Transplantation"},{"key":"10.1016\/j.intf.2026.100351_bib13","unstructured":"Monetary Authority of Singapore, Statistics: Exchange Rates. \u3008https:\/\/eservices.mas.gov.sg\/statistics\/msb\/exchangerates.aspx\u3009 (accessed 24 October 2025)."},{"key":"10.1016\/j.intf.2026.100351_bib14","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.jpedsurg.2016.02.026","article-title":"Cost of ambulatory care for the pediatric intestinal failure patient: One-year follow-up after primary discharge","volume":"51","author":"Kosar","year":"2016","journal-title":"J Pedia Surg"},{"key":"10.1016\/j.intf.2026.100351_bib15","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/j.clnu.2018.07.032","article-title":"Cost analysis of chronic intestinal failure","volume":"38","author":"Canovai","year":"2019","journal-title":"Clin Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib16","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/jpen.1690","article-title":"Safety and efficacy of teduglutide in pediatric patients with intestinal failure due to short bowel syndrome: A 24-week, phase III study","volume":"44","author":"Kocoshis","year":"2020","journal-title":"J Parent Enter Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib17","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.ajcnut.2023.02.019","article-title":"Long-term treatment with teduglutide: a 48-week open-label single-center clinical trial in children with short bowel syndrome","volume":"117","author":"Lambe","year":"2023","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpeds.2023.113882","article-title":"The impact of teduglutide on real-life health care costs in children with short bowel syndrome","volume":"272","author":"Cucinotta","year":"2024","journal-title":"J Pedia"},{"key":"10.1016\/j.intf.2026.100351_bib19","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/ajcn\/nqz269","article-title":"Cost-effectiveness of teduglutide in adult patients with short bowel syndrome: Markov modeling using traditional cost-effectiveness criteria","volume":"111","author":"Raghu","year":"2020","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib20","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/ajcn\/nqaa278","article-title":"Cost-effectiveness of teduglutide in pediatric patients with short bowel syndrome: Markov modeling using traditional cost-effectiveness criteria","volume":"113","author":"Raghu","year":"2021","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib21","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1016\/j.clnu.2023.10.001","article-title":"Cost-utility analysis of teduglutide compared to standard care in weaning parenteral nutrition support in children with short bowel syndrome","volume":"42","author":"Gattini","year":"2023","journal-title":"Clin Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib22","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1002\/jpen.2500","article-title":"Pediatric intestine transplant cost: Analysis of the Pediatric Health Information System database","volume":"47","author":"Raghu","year":"2023","journal-title":"J Parent Enter Nutr"},{"key":"10.1016\/j.intf.2026.100351_bib23","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1097\/01.tp.0000229438.14914.82","article-title":"An economic evaluation of pediatric small bowel transplantation in the United Kingdom","volume":"82","author":"Longworth","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.intf.2026.100351_bib24","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/tri.12894","article-title":"Twenty-eight years of intestinal transplantation in Paris: experience of the oldest European center","volume":"30","author":"Lacaille","year":"2017","journal-title":"Transpl Int"},{"key":"10.1016\/j.intf.2026.100351_bib25","article-title":"Pediatric intestinal transplantation: Analysis of the intestinal transplant registry","volume":"23","author":"Raghu","year":"2019","journal-title":"Pedia Transpl"}],"container-title":["Intestinal Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950456226000011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950456226000011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T09:43:58Z","timestamp":1770889438000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2950456226000011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":25,"alternative-id":["S2950456226000011"],"URL":"https:\/\/doi.org\/10.1016\/j.intf.2026.100351","relation":{},"ISSN":["2950-4562"],"issn-type":[{"value":"2950-4562","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Healthcare cost of home parenteral nutrition and intestinal transplantation for paediatric chronic intestinal failure in Singapore","name":"articletitle","label":"Article Title"},{"value":"Intestinal Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intf.2026.100351","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of International Intestinal Rehabilitation & Transplant Association.","name":"copyright","label":"Copyright"}],"article-number":"100351"}}