{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T21:09:11Z","timestamp":1788728951537,"version":"build-2803163510"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["1830522 N"],"award-info":[{"award-number":["1830522 N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","intestinalfailurejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intestinal Failure"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.intf.2026.100373","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T02:58:43Z","timestamp":1779073123000},"page":"100373","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Metabolic balance studies: A comprehensive protocol and methodological approach for assessing intestinal function"],"prefix":"10.1016","volume":"11","author":[{"given":"Julie Hvid M\u00f8ller","family":"Andersen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6130-7132","authenticated-orcid":false,"given":"Astrid","family":"Verbiest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Hvistendahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Vanuytsel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9680-6938","authenticated-orcid":false,"given":"Palle Bekker","family":"Jeppesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intf.2026.100373_bib1","first-page":"238","article-title":"Intestinal insufficiency and failure","volume":"50","author":"Jeppesen","year":"2003","journal-title":"Dan Med Bull"},{"issue":"8S","key":"10.1016\/j.intf.2026.100373_bib2","first-page":"13S","article-title":"Spectrum of short bowel syndrome in Adults","volume":"38","author":"Jeppesen","year":"2014","journal-title":"J Parent Enter Nutr"},{"key":"10.1016\/j.intf.2026.100373_bib3","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1136\/gut.46.5.701","article-title":"Intestinal failure defined by measurements of intestinal energy and wet weight absorption","volume":"46","author":"Jeppesen","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.intf.2026.100373_bib4","doi-asserted-by":"crossref","first-page":"831","DOI":"10.3945\/ajcn.117.158386","article-title":"The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure","volume":"106","author":"Prahm","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.intf.2026.100373_bib5","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1002\/jpen.1704","article-title":"Repeated metabolic balance studies in patients with short bowel syndrome","volume":"44","author":"Sun","year":"2020","journal-title":"J Parent Enter Nutr"},{"key":"10.1016\/j.intf.2026.100373_bib6","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.1021\/acs.analchem.5b04159","article-title":"Optimized sample handling strategy for metabolic profiling of human feces","volume":"88","author":"Gratton","year":"2016","journal-title":"Anal Chem"},{"key":"10.1016\/j.intf.2026.100373_bib7","unstructured":"Parr_Intro-to-Bomb-Calorimetry.pdf n.d."},{"key":"10.1016\/j.intf.2026.100373_bib8","unstructured":"Benzoic acid for calorimetrical determination (approx. 26460 J\/g) 65-85-0 n.d. \u3008https:\/\/www.sigmaaldrich.com\/DK\/en\/product\/sial\/33045?msockid=22d84bdab672649808a85e45b75b6524\u3009 (accessed May 9, 2025)."},{"key":"10.1016\/j.intf.2026.100373_bib9","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0021-9258(18)57092-7","article-title":"Rapid method for the determination of fat in feces","volume":"177","author":"van de Kamer","year":"1949","journal-title":"J Biol Chem"},{"key":"10.1016\/j.intf.2026.100373_bib10","unstructured":"Tristearin (glycerol tristearate) \u223c65%, off-white powder, Technical Grade. VWR n.d. \u3008https:\/\/dk.vwr.com\/store\/product\/9461078\/tristearin-glycerol-tristearate-65-off-white-powder-technical-grade\u3009 (accessed February 26, 2025)."},{"key":"10.1016\/j.intf.2026.100373_bib11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0021-9258(18)86093-8","article-title":"Dinitrosalicylic acid: a reagent for the estimation of sugar in normal and diabetic urine","volume":"47","author":"Sumner","year":"1921","journal-title":"J Biol Chem"},{"key":"10.1016\/j.intf.2026.100373_bib12","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.biombioe.2012.05.003","article-title":"Rapid quantification of reducing sugars in biomass hydrolysates: Improving the speed and precision of the dinitrosalicylic acid assay","volume":"44","author":"Wood","year":"2012","journal-title":"Biomass Bioenergy"},{"key":"10.1016\/j.intf.2026.100373_bib13","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1039\/b208973b","article-title":"A comparison of the Kjeldahl and Dumas methods for the determination of protein in foods, using data from a proficiency testing scheme","volume":"127","author":"Thompson","year":"2002","journal-title":"Analyst"},{"key":"10.1016\/j.intf.2026.100373_bib14","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1093\/jaoac\/82.6.1389","article-title":"Kjeldahl nitrogen analysis as a reference method for protein determination in dairy products","volume":"82","author":"Lynch","year":"1999","journal-title":"J AOAC Int"},{"key":"10.1016\/j.intf.2026.100373_bib15","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s00769-010-0677-6","article-title":"Rapid method for determination of protein content in cereals and oilseeds: validation, measurement uncertainty and comparison with the Kjeldahl method","volume":"15","author":"Beljka\u0161","year":"2010","journal-title":"Accr\u00e9dit Qual Assur"},{"key":"10.1016\/j.intf.2026.100373_bib16","unstructured":"Kjeldahl tablets, Kjeltabs. VWR n.d. \u3008https:\/\/si.vwr.com\/store\/product\/4613493\/kjeldahl-tablets-kjeltabs\u3009 (accessed February 26, 2025)."},{"key":"10.1016\/j.intf.2026.100373_bib17","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1093\/jaoac\/82.6.1389","article-title":"Kjeldahl nitrogen analysis as a reference method for protein determination in dairy products","volume":"82","author":"Lynch","year":"1999","journal-title":"J AOAC Int"},{"key":"10.1016\/j.intf.2026.100373_bib18","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/10408390701279749","article-title":"Converting nitrogen into protein\u2014beyond 6.25 and Jones\u2019 factors","volume":"48","author":"Mariotti","year":"2008","journal-title":"Crit Rev Food Sci Nutr"},{"key":"10.1016\/j.intf.2026.100373_bib19","doi-asserted-by":"crossref","DOI":"10.1088\/1742-6596\/1691\/1\/012055","article-title":"Determination of calcium and magnesium by atomic absorption spectroscopy and flame photometry","volume":"1691","author":"Bisergaeva","year":"2020","journal-title":"J Phys Conf Ser"},{"key":"10.1016\/j.intf.2026.100373_bib20","series-title":"At. Absorpt. Spectrosc","article-title":"Atomic Absorption Spectrometry (AAS)","author":"Garc\u00eda","year":"2012"},{"key":"10.1016\/j.intf.2026.100373_bib21","unstructured":"Volumetric solutions an standards for Titration. Merck_pdf n.d."},{"key":"10.1016\/j.intf.2026.100373_bib22","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1079\/PHN2001318","article-title":"Development, validation and utilisation of food-frequency questionnaires \u2013 a review","volume":"5","author":"Cade","year":"2002","journal-title":"Public Health Nutr"},{"key":"10.1016\/j.intf.2026.100373_bib23","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/ecco-jcc\/jjaa227","article-title":"Metabolomic analysis in inflammatory bowel disease: a systematic review","volume":"15","author":"Gallagher","year":"2021","journal-title":"J Crohns Colitis"},{"key":"10.1016\/j.intf.2026.100373_bib24","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.clnesp.2025.03.029","article-title":"Transferability of metabolic balance studies in short bowel syndrome","volume":"67","author":"Verbiest","year":"2025","journal-title":"Clin Nutr ESPEN"}],"container-title":["Intestinal Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950456226000230?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950456226000230?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T20:18:20Z","timestamp":1788725900000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2950456226000230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":24,"alternative-id":["S2950456226000230"],"URL":"https:\/\/doi.org\/10.1016\/j.intf.2026.100373","relation":{},"ISSN":["2950-4562"],"issn-type":[{"value":"2950-4562","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metabolic balance studies: A comprehensive protocol and methodological approach for assessing intestinal function","name":"articletitle","label":"Article Title"},{"value":"Intestinal Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intf.2026.100373","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of International Intestinal Rehabilitation & Transplant Association.","name":"copyright","label":"Copyright"}],"article-number":"100373"}}