{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:58:44Z","timestamp":1787273924093,"version":"build-2736575974"},"reference-count":33,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1016\/j.intimp.2004.03.005","type":"journal-article","created":{"date-parts":[[2004,4,13]],"date-time":"2004-04-13T10:22:09Z","timestamp":1081851729000},"page":"841-849","source":"Crossref","is-referenced-by-count":50,"title":["Immune response modulation to DPT vaccine by aqueous extract of Withania somnifera in experimental system"],"prefix":"10.1016","volume":"4","author":[{"given":"M","family":"Gautam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.S","family":"Diwanay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Gairola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.S","family":"Shinde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.S","family":"Jadhav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.K","family":"Patwardhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.intimp.2004.03.005_BIB1","first-page":"105","article-title":"Immunomodulators in the prevention of acute respiratory viral infections","author":"Semenenko","year":"2002","journal-title":"Russ. J. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2004.03.005_BIB2","first-page":"156","article-title":"Recent developments in mucosal immunomodulatory adjuvants","volume":"4","author":"Harandi","year":"2003","journal-title":"Curr. Opin. Investig. Drugs"},{"key":"10.1016\/j.intimp.2004.03.005_BIB3","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0264-410X(93)90190-9","article-title":"Adjuvants\u2014A balance between toxicity and adjuvanicity","volume":"11","author":"Gupta","year":"1993","journal-title":"Vaccine"},{"key":"10.1016\/j.intimp.2004.03.005_BIB4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ilar.37.3.119","article-title":"Review of selected adjuvants used in Antibody production","volume":"37","author":"Jennings","year":"1995","journal-title":"ILAR J."},{"issue":"3","key":"10.1016\/j.intimp.2004.03.005_BIB5","doi-asserted-by":"crossref","first-page":"273","DOI":"10.2174\/1568005014606008","article-title":"Recent developments in vaccine delivery systems","volume":"1","author":"Hagan","year":"2001","journal-title":"Curr. Drug Targets. Infect. Disord."},{"issue":"3","key":"10.1016\/j.intimp.2004.03.005_BIB6","doi-asserted-by":"crossref","first-page":"263","DOI":"10.2174\/1568005014605991","article-title":"Novel adjuvant systems","volume":"1","author":"Mc Cluskie","year":"2001","journal-title":"Curr. Drug Targets. Infect. Discord."},{"key":"10.1016\/j.intimp.2004.03.005_BIB7","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0192-0561(88)90066-5","article-title":"Low molecular weight immunopotentiators","volume":"64","author":"Ruszala","year":"1988","journal-title":"Int. J. Immunophamacol."},{"issue":"1","key":"10.1016\/j.intimp.2004.03.005_BIB8","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0165-2427(02)00269-6","article-title":"Ginseng extract in aluminum hydroxide adjuvant vaccines improves the antibody response of pigs to porcine parvovirus and Erysipelothrix rhusiopathiae","volume":"91","author":"Rivera","year":"2003","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"1","key":"10.1016\/j.intimp.2004.03.005_BIB9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0165-2427(02)00264-7","article-title":"Adjuvant effect of ginseng extracts on the immune responses to immunization against Staphylococcus aureus in dairy cattle","volume":"91","author":"Hu","year":"2003","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"2","key":"10.1016\/j.intimp.2004.03.005_BIB10","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1046\/j.1365-2567.2002.01492.x","article-title":"Mistletoe lectins enhance immune responses to intranasally co-administered herpes simplex virus glycoprotein D2","volume":"107","author":"Lavelle","year":"2002","journal-title":"Immunology"},{"issue":"4","key":"10.1016\/j.intimp.2004.03.005_BIB11","first-page":"119","article-title":"Immunomodulation by herbal agents. A double-blind study in a medical university hospital involving a hepatitis B vaccine adjuvant model","volume":"120","author":"Bostelmann","year":"2002","journal-title":"Fortschr. Med. Orig."},{"issue":"S","key":"10.1016\/j.intimp.2004.03.005_BIB12","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1086\/313883","article-title":"Improving Vaccine performance with Adjuvants","volume":"30","author":"Frederick","year":"2000","journal-title":"Clin. Infect. Dis."},{"issue":"27\u201328","key":"10.1016\/j.intimp.2004.03.005_BIB13","first-page":"3237","article-title":"QS-21 structure\/function studies: effect of acylation on adjuvant activity","volume":"20","author":"Liu","year":"2002","journal-title":"Vaccine"},{"issue":"17\u201318","key":"10.1016\/j.intimp.2004.03.005_BIB14","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1016\/S0264-410X(02)00115-9","article-title":"Safety tolerability and immunogenecity of new formulations of Plasmodium falciparum malaria peptide vaccine SPF 66 combined with immunological adjuvant QS-21","volume":"20","author":"Kashala","year":"2002","journal-title":"Vaccine"},{"key":"10.1016\/j.intimp.2004.03.005_BIB15","series-title":"The legacy of Caraka","author":"Valiathan","year":"2003"},{"issue":"5","key":"10.1016\/j.intimp.2004.03.005_BIB16","first-page":"213","article-title":"Ayurveda: The designer medicine: Review of Ethno pharmacology and Bioprospecting research","volume":"37","author":"Patwardhan","year":"2000","journal-title":"Indian Drugs"},{"key":"10.1016\/j.intimp.2004.03.005_BIB17","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/(SICI)1099-1573(199906)13:4<275::AID-PTR510>3.0.CO;2-S","article-title":"Adaptogenic properties of six Rasayana herbs in Ayurvedic Medicine","volume":"13","author":"Rege","year":"1999","journal-title":"Phytother. Res."},{"key":"10.1016\/j.intimp.2004.03.005_BIB18","first-page":"56","article-title":"Search of immunomodulatory agents: a review","volume":"28","author":"Patwardhan","year":"1990","journal-title":"Indian Drugs"},{"key":"10.1016\/j.intimp.2004.03.005_BIB19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0378-8741(99)00065-3","article-title":"Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) in experimental immune inflammation","volume":"67","author":"Agarwal","year":"1999","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2004.03.005_BIB20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0378-8741(95)01318-0","article-title":"Studies on the immunomodulatory effects of Ashwagandha","volume":"50","author":"Ziauddin","year":"1996","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2004.03.005_BIB21","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0378-8741(94)01119-2","article-title":"Comparative pharmacology of Ashwagandha and Ginseng","volume":"44","author":"Grandhi","year":"1994","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2004.03.005_BIB22","unstructured":"Indian Herbal Pharmacopoeia. Joint publication of Indian Drugs Manufacturer's Association and Regional Research Laboratory Jammu\u2013Tawi 1998; 1:165\u201373."},{"key":"10.1016\/j.intimp.2004.03.005_BIB23","first-page":"15","volume":"vol. I (1)","year":"1989"},{"issue":"4","key":"10.1016\/j.intimp.2004.03.005_BIB24","first-page":"334","article-title":"Scientific basis for the therapeutic use of Withania somnifera (Ashwagandha): a review","volume":"5","author":"Mishra","year":"2000","journal-title":"Altern. Med. Rev."},{"key":"10.1016\/j.intimp.2004.03.005_BIB25","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/ptr.2650010108","article-title":"Anti-stress activity of sitoindosides VII and VIII, new Acylsterylglucosides from Withania somnifera","volume":"1","author":"Bhattacharya","year":"1987","journal-title":"Phytother. Res."},{"key":"10.1016\/j.intimp.2004.03.005_BIB26","series-title":"Thin Layer Chromatography\u2014A Laboratory Handbook","first-page":"311","author":"Stahl","year":"1964"},{"key":"10.1016\/j.intimp.2004.03.005_BIB27","first-page":"72","article-title":"Requirements for diptheria, pertussis, tetanus and combined vaccines","volume":"800","year":"1990","journal-title":"WHO Tech. Ser."},{"key":"10.1016\/j.intimp.2004.03.005_BIB28","series-title":"A Handbook of Practical Immunology","first-page":"155","author":"Talwar","year":"1983"},{"key":"10.1016\/j.intimp.2004.03.005_BIB29","first-page":"320","article-title":"Theoretical outline on the preparation of non-cellular pertussis vaccine","volume":"vol. 9-1830","author":"Zakharova","year":"1979"},{"key":"10.1016\/j.intimp.2004.03.005_BIB30","first-page":"99","article-title":"Effect of growth condition on the composition and stability of outer membrane of B. Pertussis","volume":"vol. 19-1830","author":"Novotny","year":"1979"},{"key":"10.1016\/j.intimp.2004.03.005_BIB31","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1017\/S0022172400069874","article-title":"A reappraisal of serotype factors 4,5 and 6 of B. pertussis","volume":"88","author":"Preston","year":"1982","journal-title":"J. Hyg. (Camb)."},{"key":"10.1016\/j.intimp.2004.03.005_BIB32","doi-asserted-by":"crossref","first-page":"803","DOI":"10.2105\/AJPH.37.7.803-b","article-title":"Mouse protection test in the study of pertussis vaccine","volume":"37","author":"Kendrick","year":"1947","journal-title":"Am. J. Publ. Health"},{"key":"10.1016\/j.intimp.2004.03.005_BIB33","first-page":"264","volume":"vol. 1","year":"1996"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576904000827?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576904000827?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T03:22:30Z","timestamp":1550114550000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576904000827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["S1567576904000827"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2004.03.005","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}