{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T07:07:56Z","timestamp":1694502476288},"reference-count":61,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.1016\/j.intimp.2007.02.015","type":"journal-article","created":{"date-parts":[[2007,4,5]],"date-time":"2007-04-05T11:11:57Z","timestamp":1175771517000},"page":"1003-1012","source":"Crossref","is-referenced-by-count":7,"title":["15-deoxyspergualin prevents mucosal injury by inhibiting production of TNF-\u03b1 and down-regulating expression of MD-1 in a murine model of TNBS-induced colitis"],"prefix":"10.1016","volume":"7","author":[{"given":"Jienny","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung-Sunny","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun-Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hae-Jung","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Young","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da-Yeon","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Choon-Hyuck","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Won","family":"Joh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Joo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2007.02.015_bib1","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0016-5085(98)70381-6","article-title":"Inflammatory bowel disease: aetiology and pathogenesis","volume":"115","author":"Fiocchi","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2007.02.015_bib2","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/ibd.3780060208","article-title":"Probiotics and inflammatory bowel disease: is there a scientific rationale?","volume":"6","author":"Shanahan","year":"2000","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.intimp.2007.02.015_bib3","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1053\/gast.2001.22122","article-title":"IBD: Immunodiagnostics immunotherapeutics and ectotherapeutics","volume":"120","author":"Shanahan","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2007.02.015_bib4","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1053\/gast.2002.33426","article-title":"Biologic therapy of IBD","volume":"122","author":"Sandborn","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2007.02.015_bib5","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1046\/j.1365-3083.2000.00657.x","article-title":"Immunotherapy of Crohn's disease","volume":"51","author":"Van Deventer","year":"2000","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib6","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1056\/NEJM199603283341307","article-title":"Inflammatory bowel disease","volume":"334","author":"Hanauer","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.intimp.2007.02.015_bib7","first-page":"871","article-title":"Deoxyspergualin: clinical experience","volume":"28","author":"Gores","year":"1996","journal-title":"Transplant Proc"},{"key":"10.1016\/j.intimp.2007.02.015_bib8","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.7164\/antibiotics.34.1619","article-title":"A new antitumor antibiotic, spergualin: isolation and antitumor activity","volume":"34","author":"Takeuchi","year":"1981","journal-title":"J Antibiot"},{"key":"10.1016\/j.intimp.2007.02.015_bib9","first-page":"328","article-title":"Inhibition of antibody production by the immunosuppressive agent, 15-deoxyspergualin","volume":"23","author":"Tepper","year":"1991","journal-title":"Transplant Proc"},{"key":"10.1016\/j.intimp.2007.02.015_bib10","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1084\/jem.183.6.2427","article-title":"The immunosuppressant 15-deoxyspergualin reveals commonality between pre T and pre B cell differentiation","volume":"183","author":"Wang","year":"1996","journal-title":"J Exp Med"},{"key":"10.1016\/j.intimp.2007.02.015_bib11","first-page":"873","article-title":"Deoxyspergualin: mechanism of action and pharmacokinetics","volume":"28","author":"Ramos","year":"1996","journal-title":"Transplant Proc"},{"key":"10.1016\/j.intimp.2007.02.015_bib12","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.7164\/antibiotics.39.1461","article-title":"Antitumor activity of spergualin, a novel antitumor antibiotic","volume":"39","author":"Nishikawa","year":"1986","journal-title":"J Antibiot"},{"key":"10.1016\/j.intimp.2007.02.015_bib13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/00007890-199008000-00001","article-title":"15-Deoxyspergualin for induction of graft nonreactivity after cardiac and renal allotransplantation in primates","volume":"50","author":"Reichenspurner","year":"1990","journal-title":"Transplantation"},{"key":"10.1016\/j.intimp.2007.02.015_bib14","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1681\/ASN.V3111765","article-title":"Suppression of experimental crescentic glomerulonephritis by deoxyspergualin","volume":"3","author":"Lan","year":"1993","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.intimp.2007.02.015_bib15","first-page":"315","article-title":"15-Deoxyspergualin controls cyclosporin-and steroid-resistant intestinal acute graft-versus-host disease after allogeneic bone marrow transplantation","volume":"14","author":"Kasai","year":"1994","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.intimp.2007.02.015_bib16","first-page":"3993","article-title":"Xenogeneic heart transplantation with 15-deoxyspergualin: prolongation of graft survival","volume":"19","author":"Walter","year":"1987","journal-title":"Transplant Proc"},{"key":"10.1016\/j.intimp.2007.02.015_bib17","first-page":"417","article-title":"Deoxyspergualin is a unique immunosuppressive agent with selective utility in inducing tolerance to pancreas islet xenografts","volume":"27","author":"Thomas","year":"1995","journal-title":"Transplant Proc"},{"key":"10.1016\/j.intimp.2007.02.015_bib18","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1172\/JCI200317477","volume":"111","author":"Adams","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.intimp.2007.02.015_bib19","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1749-6632.1993.tb35862.x","article-title":"Preclinical studies with 15-deoxyspergualin in various animal models of autoimmune diseases","volume":"685","author":"Schorlemmer","year":"1993","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.intimp.2007.02.015_bib20","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1600-065X.1995.tb00072.x","article-title":"Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis","volume":"144","author":"Olsson","year":"1995","journal-title":"Immunol Rev"},{"key":"10.1016\/j.intimp.2007.02.015_bib21","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1093\/ndt\/gfi070","article-title":"15-Deoxyspergualin and cyclophosphamide, but not mycophenolate mofetil, prolong survival and attenuate renal disease in a murine model of ANCA-associated crescentic nephritis","volume":"21","author":"Birck","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.intimp.2007.02.015_bib22","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/j.1365-2141.1995.tb05370.x","article-title":"Autoimmune-prone (Nzw\u00d7BXSB)F1 (W\/BF1) mice escape severe thrombocytopenia after treatment with deoxyspergualin, an immunosuppressant","volume":"91","author":"Nemoto","year":"1995","journal-title":"Br J Haematol"},{"key":"10.1016\/j.intimp.2007.02.015_bib23","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/01.ASN.0000048716.42876.14","article-title":"15-Deoxyspergualin in patients with refractory ANCA-associated systemic vasculitis: a six-month open-label trial to evaluate safety and efficacy","volume":"14","author":"Birck","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.intimp.2007.02.015_bib24","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/1074-7613(94)90045-0","article-title":"Inhibition of Th1 responses prevents inflammatory bowel disease in SCID mice reconstituted with CD45RBhi CD4+ T cells","volume":"1","author":"Powrie","year":"1994","journal-title":"Immunity"},{"key":"10.1016\/j.intimp.2007.02.015_bib25","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1084\/jem.190.10.1479","article-title":"Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2\u2212\/\u2212mice upon transfer of CD4+ CD45RBhi T cells","volume":"190","author":"Corazza","year":"1999","journal-title":"J Exp Med"},{"key":"10.1016\/j.intimp.2007.02.015_bib26","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1053\/gast.2001.29579","article-title":"Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-\u03b1 production in mice","volume":"121","author":"Ten Hove","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2007.02.015_bib27","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1172\/JCI200420855","article-title":"Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease","volume":"114","author":"Olson","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.intimp.2007.02.015_bib28","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.4049\/jimmunol.161.3.1348","article-title":"MD-1, a molecule that is physically associated with RP105 and positively regulates its expression","volume":"161","author":"Miyake","year":"1998","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1749-6632.1993.tb35863.x","article-title":"15-deoxyspergualin: a novel immunosuppressive drug with clinical potential","volume":"685","author":"Thomas","year":"1993","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.intimp.2007.02.015_bib30","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.7164\/antibiotics.40.1193","article-title":"Suppression of experimental allergic encephalomyelitis in guinea pigs by spergualin and 15-deoxyspergualin","volume":"40","author":"Nemoto","year":"1987","journal-title":"J Antibiot"},{"key":"10.1016\/j.intimp.2007.02.015_bib31","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1097\/00007890-199103000-00032","article-title":"Deoxyspergualin in lethal murine graft-versus-host disease","volume":"51","author":"Nemoto","year":"1991","journal-title":"Transplantation"},{"key":"10.1016\/j.intimp.2007.02.015_bib32","first-page":"1606","article-title":"Effect of a novel immunosuppressive, deoxyspergualin, on rejection in kidney transplant recipients","volume":"22","author":"Takahashi","year":"1990","journal-title":"Transplant Proc"},{"key":"10.1016\/j.intimp.2007.02.015_bib33","first-page":"175","article-title":"Multicentre clinical trial of antirejection pulse therapy with deoxyspergualin in kidney transplant patients","volume":"11","author":"Amemiya","year":"1991","journal-title":"Int J Clin Pharmacol Res"},{"key":"10.1016\/j.intimp.2007.02.015_bib34","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/0140-6736(90)93419-P","article-title":"Deoxyspergualin for liver graft rejection","volume":"8","author":"Groth","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.intimp.2007.02.015_bib35","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0162-3109(87)90036-1","article-title":"Immunosuppressive activities of deoxyspergualin: the effect on the antibody responses","volume":"14","author":"Makino","year":"1998","journal-title":"Immunopharmacology"},{"key":"10.1016\/j.intimp.2007.02.015_bib36","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.7164\/antibiotics.41.1253","article-title":"Biological activities of deoxyspergualin in autoimmune disease mice","volume":"41","author":"Nemoto","year":"1988","journal-title":"J Antibiot"},{"key":"10.1016\/j.intimp.2007.02.015_bib37","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1146\/annurev.iy.12.040194.001041","article-title":"Function and activation of NF-kappa B in the immune system","volume":"12","author":"Baeuerle","year":"1994","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib38","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1056\/NEJM199704103361506","article-title":"Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases","volume":"336","author":"Barnes","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.intimp.2007.02.015_bib39","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.4049\/jimmunol.155.5.2427","article-title":"Deoxyspergualin inhibits kappa light chain expression in 70Z\/3 pre-B cells by blocking lipopolysaccharide-induced NF-kappa B activation","volume":"155","author":"Tepper","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib40","doi-asserted-by":"crossref","first-page":"3908","DOI":"10.4049\/jimmunol.153.9.3908","article-title":"Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes","volume":"153","author":"Hoeger","year":"1994","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib41","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1146\/annurev.cb.10.110194.002201","article-title":"Structure, regulation and function of NF-kappa B","volume":"10","author":"Siebenlist","year":"1994","journal-title":"Annu Rev Cell Biol"},{"key":"10.1016\/j.intimp.2007.02.015_bib42","doi-asserted-by":"crossref","first-page":"3474","DOI":"10.4049\/jimmunol.163.6.3474","article-title":"Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity","volume":"163","author":"Jobin","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib43","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1365-2249.1993.tb05997.x","article-title":"Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease","volume":"94","author":"Reinecker","year":"1993","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib44","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1007\/s002689900401","article-title":"Cytokines in inflammatory bowel disease","volume":"22","author":"Rogler","year":"1998","journal-title":"World J Surg"},{"key":"10.1016\/j.intimp.2007.02.015_bib45","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1152\/ajpcell.00113.2001","article-title":"MAP kinases contribute to IL-8 secretion by intestinal epithelial cells via a posttranscriptional mechanism","volume":"283","author":"Jijon","year":"2002","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.intimp.2007.02.015_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2776(01)78001-7","article-title":"Toll-like receptors and innate immunity","volume":"78","author":"Akira","year":"2001","journal-title":"Adv Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib47","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/35092578","article-title":"Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction","volume":"6","author":"Fitzgerald","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2007.02.015_bib48","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1038\/ni0901-835","article-title":"TIRAP: an adapter molecule in the Toll signaling pathway","volume":"2","author":"Horng","year":"2001","journal-title":"Nat Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib49","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1097\/00007890-200206150-00013","article-title":"Antisense deoxyoligonucleotides or antibodies to murine MD-1 inhibit rejection of allogeneic and xenogeneic skin grafts in C3H mice","volume":"73","author":"Hadidi","year":"2002","journal-title":"Transplantation"},{"key":"10.1016\/j.intimp.2007.02.015_bib50","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1038\/35021228","article-title":"Toll-like receptors in the induction of the innate immune response","volume":"406","author":"Aderem","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2007.02.015_bib51","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1146\/annurev.immunol.21.120601.141126","article-title":"Toll-like receptors","volume":"21","author":"Takeda","year":"2003","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib52","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/ni1198","article-title":"Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105","volume":"6","author":"Divanovic","year":"2005","journal-title":"Nat Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib53","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1084\/jem.20021633","article-title":"Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide","volume":"197","author":"Caramalho","year":"2003","journal-title":"J Exp Med"},{"key":"10.1016\/j.intimp.2007.02.015_bib54","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1084\/jem.188.1.93","article-title":"The molecular mechanism of B cell activation by toll-like receptor protein RP-105","volume":"188","author":"Chan","year":"1998","journal-title":"J Exp Med"},{"key":"10.1016\/j.intimp.2007.02.015_bib55","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1084\/jem.187.5.663","article-title":"B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells","volume":"187","author":"Grumont","year":"1998","journal-title":"J Exp Med"},{"key":"10.1016\/j.intimp.2007.02.015_bib56","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1053\/j.gastro.2004.03.015","article-title":"Colitis is associated with thymic destruction attenuating CD4+ CD25+ regulatory T cells in the periphery","volume":"126","author":"Faubion","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2007.02.015_bib57","doi-asserted-by":"crossref","first-page":"3119","DOI":"10.4049\/jimmunol.173.5.3119","article-title":"CD4+ CD25bright T cells in human intestinal lamina propria as regulatory cells","volume":"173","author":"Makita","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2007.02.015_bib58","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1046\/j.1365-2567.1998.00606.x","article-title":"Immunosuppressant deoxyspergualin induces apoptotic cell death in dividing cells","volume":"95","author":"Odaka","year":"1998","journal-title":"Immunology"},{"key":"10.1016\/j.intimp.2007.02.015_bib59","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/nm1107","article-title":"4-1BB-mediated immunotherapy of rheumatoid arthritis","volume":"10","author":"Seo","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.intimp.2007.02.015_bib60","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1126\/science.281.5380.1191","article-title":"Prevention of allogeneic fetal rejection by tryptophan catabolism","volume":"281","author":"Munn","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.intimp.2007.02.015_bib61","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1038\/ni1003","article-title":"Modulation of tryptophan catabolism by regulatory T cells","volume":"4","author":"Fallarino","year":"2003","journal-title":"Nat Immunol"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576907000628?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576907000628?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T09:51:03Z","timestamp":1683798663000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576907000628"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":61,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["S1567576907000628"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2007.02.015","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2007,8]]}}}