{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T07:52:27Z","timestamp":1758268347477,"version":"3.37.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2009,8]]},"DOI":"10.1016\/j.intimp.2009.04.016","type":"journal-article","created":{"date-parts":[[2009,5,10]],"date-time":"2009-05-10T09:19:42Z","timestamp":1241947182000},"page":"1071-1078","source":"Crossref","is-referenced-by-count":7,"title":["Hepatic platelet accumulation in Fas-mediated hepatitis in mice"],"prefix":"10.1016","volume":"9","author":[{"given":"Yuko","family":"Ohtaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouji","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiqian","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kumamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidetoshi","family":"Shimauchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichiro","family":"Iwakura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunji","family":"Sugawara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Endo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2009.04.016_bib1","doi-asserted-by":"crossref","first-page":"4182","DOI":"10.1128\/IAI.61.10.4182-4187.1993","article-title":"An effector role for platelets in systemic and local lipopolysaccharide-induced toxicity in mice, mediated by a CD11a- and CD54-dependent interaction with endothelium","volume":"61","author":"Piguet","year":"1993","journal-title":"Infect Immun"},{"key":"10.1016\/j.intimp.2009.04.016_bib2","first-page":"139","article-title":"Platelet-activating factor is a mediator in tumor necrosis factor\/galactosamine-induced lethality","volume":"46","author":"Libert","year":"1996","journal-title":"J Inflam"},{"key":"10.1016\/j.intimp.2009.04.016_bib3","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.4049\/jimmunol.159.7.3555","article-title":"\u03b11-Acid glycoprotein and \u03b11-antitrypsin inhibit TNF-induced but not anti-Fas-induced apoptosis of hepatocytes in mice","volume":"159","author":"Van Molle","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2009.04.016_bib4","doi-asserted-by":"crossref","first-page":"5290","DOI":"10.1128\/IAI.64.12.5290-5294.1996","article-title":"Biphasic, organ-specific, and strain-specific accumulation of platelets induced in mice by a lipopolysaccharide from Escherichia coli and its possible involvement in shock","volume":"64","author":"Shibazaki","year":"1996","journal-title":"Infect Immun"},{"key":"10.1016\/j.intimp.2009.04.016_bib5","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/hep.510270225","article-title":"Involvement of intrasinusoidal hemostasis in the development of concanavalin A-induced hepatic injury in mice","volume":"27","author":"Miyazawa","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.intimp.2009.04.016_bib6","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/j.1476-5381.1984.tb16130.x","article-title":"Induction of hypoglycaemia and accumulation of 5-hydroxytryptamine in the liver after injection of mitogenic substances into mice","volume":"81","author":"Endo","year":"1984","journal-title":"Brit J Pharmacol"},{"key":"10.1016\/j.intimp.2009.04.016_bib7","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.1476-5381.1992.tb09028.x","article-title":"The effect of lipopolysaccharide, interleukin-1 and tumour necrosis factor on the hepatic accumulation of 5-hydroxytryptamine and platelets in the mouse","volume":"105","author":"Endo","year":"1992","journal-title":"Brit J Pharmacol"},{"key":"10.1016\/j.intimp.2009.04.016_bib8","doi-asserted-by":"crossref","first-page":"3056","DOI":"10.1161\/01.CIR.99.23.3056","article-title":"Reduction in lipopolysaccharide-induced thrombocytopenia by triflavin in a rat model of septicemia","volume":"99","author":"Sheu","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.intimp.2009.04.016_bib9","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1182\/blood-2002-01-0252","article-title":"LPS-induced platelet response and rapid shock in mice: contribution of O-antigen region of LPS and involvement of the lectin pathway of the complement system","volume":"100","author":"Zhao","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2009.04.016_bib10","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.bbadis.2005.11.010","article-title":"Involvement of Kupffer cells in lipopolysaccharide-induced rapid accumulation of platelets in the liver and the ensuing anaphylaxis-like shock in mice","volume":"1762","author":"Yamaguchi","year":"2006","journal-title":"Biochem Biophys Acta (Mol Basis Dis)"},{"key":"10.1016\/j.intimp.2009.04.016_bib11","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/S0168-8278(98)80348-6","article-title":"Translocation of platelets into Disse spaces and their entry into hepatocytes in response to lipopolysaccharides, interleukin-1 and tumor necrosis factor: the role of Kupffer cells","volume":"28","author":"Nakamura","year":"1998","journal-title":"J Hepatol"},{"key":"10.1016\/j.intimp.2009.04.016_bib12","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1046\/j.1440-1711.2002.01068.x","article-title":"Activation-induced cell death: the controversial role of Fas and Fas ligand in immune privilege and tumour counterattack","volume":"80","author":"Maher","year":"2002","journal-title":"Immunol Cell Biol"},{"key":"10.1016\/j.intimp.2009.04.016_bib13","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1189\/jlb.69.1.123","article-title":"Activated human platelets express Fas-L and induce apoptosis in Fas-positive tumor cells","volume":"69","author":"Ahmad","year":"2001","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.intimp.2009.04.016_bib14","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0092-8674(00)81874-7","article-title":"Apoptosis by death factors","volume":"88","author":"Nagata","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.intimp.2009.04.016_bib15","first-page":"G354","article-title":"Fas and Fas ligand in gut and liver","volume":"278","author":"Pinkoski","year":"2000","journal-title":"Am J Physiol"},{"key":"10.1016\/j.intimp.2009.04.016_bib16","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/364806a0","article-title":"Lethal effect of the anti-Fas antibody in mice","volume":"364","author":"Ogasawara","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2009.04.016_bib17","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1084\/jem.187.9.1463","article-title":"Production of mice deficient in genes for interleukin(IL)-1\u03b1, IL-1\u03b2, IL-1\u03b1\/\u03b2, and IL-1 receptor antagonist shows that IL-1\u03b2 is crucial in turpentine-induced fever development and glucocorticoid secretion","volume":"187","author":"Horai","year":"1998","journal-title":"J Exp Med"},{"key":"10.1016\/j.intimp.2009.04.016_bib18","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.4049\/jimmunol.159.3.1418","article-title":"Suppression of concanavalin A-induced hepatitis in IFN-\u03b3\u2212\/\u2212 mice, but not in TNF\u03b1\u2212\/\u2212 mice","volume":"159","author":"Tagawa","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2009.04.016_bib19","doi-asserted-by":"crossref","first-page":"19673","DOI":"10.1074\/jbc.270.34.19673","article-title":"Thrombopoietin induces megakaryocyte differentiation in hematopoietic progenitor FDC-P2 cells","volume":"270","author":"Nagata","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/j.intimp.2009.04.016_bib20","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0022-3565(25)33551-2","article-title":"Mouse antithrombotic assay: a simple method for evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethanol alcohol","volume":"225","author":"Di Minno","year":"1983","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.intimp.2009.04.016_bib21","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0160-5402(86)90057-4","article-title":"A minimally invasive technique for study of intravascular platelet aggregation in anesthetized rats","volume":"15","author":"Oyekan","year":"1986","journal-title":"J Pharmacol Method"},{"key":"10.1016\/j.intimp.2009.04.016_bib22","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0049-3848(03)00092-6","article-title":"In vivo platelet response to lipopolysaccharide in mice: proposed method for evaluating new antiplatelet drugs","volume":"108","author":"Ohtaki","year":"2003","journal-title":"Thromb Res"},{"key":"10.1016\/j.intimp.2009.04.016_bib23","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0165-2478(91)90248-9","article-title":"Parallel relationship between the increase in serotonin in the liver and the hypoglycaemia induced in mice by interleukin-1 and tumor necrosis factor","volume":"27","author":"Endo","year":"1991","journal-title":"Immunol Lett"},{"key":"10.1016\/j.intimp.2009.04.016_bib24","first-page":"1307","article-title":"Primary role of interleukin-1\u03b1 and interleukin-1\u03b2 in lipopolysaccharide-induced hypoglycemia in mice","volume":"9","author":"Oguri","year":"2002","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1016\/j.intimp.2009.04.016_bib25","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1182\/blood.V77.8.1627.1627","article-title":"Interleukin-1 and interleukin-1 antagonism","volume":"77","author":"Dinarello","year":"1991","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2009.04.016_bib26","first-page":"647","article-title":"Failure of germinal center formation and impairment of response to endotoxin in tumor necrosis factor \u03b1-deficient mice","volume":"77","author":"Taniguchi","year":"1997","journal-title":"Lab Invest"},{"key":"10.1016\/j.intimp.2009.04.016_bib27","doi-asserted-by":"crossref","first-page":"G583","DOI":"10.1152\/ajpgi.00422.2005","article-title":"Mechanisms of liver injury. I. TNF-\u03b1-induced liver injury: role of IKK, JNK, and ROS pathways","volume":"290","author":"Schwabe","year":"2006","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.intimp.2009.04.016_bib28","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1086\/516120","article-title":"The role of platelets in an anti-microbial host defense","volume":"25","author":"Yeaman","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.intimp.2009.04.016_bib29","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.it.2004.07.003","article-title":"Platelets: signaling cells in the immune continuum","volume":"25","author":"Weyrich","year":"2004","journal-title":"Trends Immunol"},{"key":"10.1016\/j.intimp.2009.04.016_bib30","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/0268-960X(93)90024-X","article-title":"Platelet \u03b1-granules","volume":"7","author":"Harrison","year":"1993","journal-title":"Blood Rev"},{"key":"10.1016\/j.intimp.2009.04.016_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s004290050075","article-title":"Platelets and inflammation","volume":"196","author":"Klinger","year":"1997","journal-title":"Anat Embryol"},{"key":"10.1016\/j.intimp.2009.04.016_bib32","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1083\/jcb.200105058","article-title":"Activated platelets mediate inflammatory signaling by regulated interleukin 1 \u03b2 synthesis","volume":"154","author":"Lindemann","year":"2001","journal-title":"J Cell Biol"},{"key":"10.1016\/j.intimp.2009.04.016_bib33","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1182\/blood.V91.1.134","article-title":"Platelet-derived interleukin-1 induces cytokine production but not proliferation of human vascular smooth muscle cells","volume":"91","author":"Loppnow","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2009.04.016_bib34","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0014-4800(64)90045-0","article-title":"The mechanism of the endothelial supporting function of intact platelets","volume":"3","author":"Johnson","year":"1964","journal-title":"Exp Mol Pathol"},{"key":"10.1016\/j.intimp.2009.04.016_bib35","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1126\/science.282.5396.2085","article-title":"Defective LPS signaling in C3H\/HeJ and C57BL\/10ScCr mice","volume":"282","author":"Poltrak","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.intimp.2009.04.016_bib36","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1084\/jem.189.4.615","article-title":"Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)","volume":"189","author":"Qureshi","year":"1999","journal-title":"J Exp Med"},{"key":"10.1016\/j.intimp.2009.04.016_bib37","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1172\/JCI26252","article-title":"Caspases: pharmacological manipulation of cell death","volume":"115","author":"Lavrik","year":"2005","journal-title":"J Clin Investig"},{"key":"10.1016\/j.intimp.2009.04.016_bib38","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/j.1365-2362.1990.tb01911.x","article-title":"Thrombin-antithrombin III complex in fulminant hepatic failure: evidence for disseminated intravascular coagulation and relationship to outcome","volume":"20","author":"Langley","year":"1990","journal-title":"Eur J Clin Investig"},{"key":"10.1016\/j.intimp.2009.04.016_bib39","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.hepres.2004.03.011","article-title":"Apoptotic hepatocellular carcinoma HepG2 cells accelerate blood coagulation","volume":"29","author":"Miyamoto","year":"2004","journal-title":"Hepatol Res"},{"key":"10.1016\/j.intimp.2009.04.016_bib40","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1182\/blood.V65.2.319.319","article-title":"The role of activated platelets in prothrombin and factor X activation","volume":"65","author":"Rosing","year":"1985","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2009.04.016_bib41","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1126\/science.1123842","article-title":"Platelet-derived serotonin mediates liver regeneration","volume":"312","author":"Lesurtel","year":"2006","journal-title":"Science"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576909001659?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576909001659?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T10:07:22Z","timestamp":1739095642000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576909001659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["S1567576909001659"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2009.04.016","relation":{},"ISSN":["1567-5769"],"issn-type":[{"type":"print","value":"1567-5769"}],"subject":[],"published":{"date-parts":[[2009,8]]}}}