{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T19:51:59Z","timestamp":1770839519293,"version":"3.50.1"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31172305"],"award-info":[{"award-number":["31172305"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"BigDNA Ltd, Scotland, UK"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.intimp.2013.04.027","type":"journal-article","created":{"date-parts":[[2013,5,11]],"date-time":"2013-05-11T03:39:14Z","timestamp":1368243554000},"page":"505-510","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Evaluation of an ompA-based phage-mediated DNA vaccine against Chlamydia abortus in piglets"],"prefix":"10.1016","volume":"16","author":[{"given":"Changbo","family":"Ou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deyu","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Ling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis O.","family":"Eko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2013.04.027_bb0005","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1099\/jmm.0.05093-0","article-title":"Chlamydial vaccine development","volume":"52","author":"Longbottom","year":"2003","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0010","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.vetmic.2008.09.029","article-title":"Chlamydophila abortus infection in the mouse: a useful model of the ovine disease","volume":"135","author":"Caro","year":"2009","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0015","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S1357-4310(98)01232-5","article-title":"Vaccines against Chlamydia: approaches and progress","volume":"4","author":"Stagg","year":"1998","journal-title":"Mol. Med. Today"},{"key":"10.1016\/j.intimp.2013.04.027_bb0020","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.4049\/jimmunol.173.5.3375","article-title":"A novel recombinant multisubunit vaccine against Chlamydia","volume":"173","author":"Eko","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0025","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1128\/AAC.49.3.903-907.2005","article-title":"Emergence of resistance to rifampin and rifalazil in Chlamydophila pneumoniae and Chlamydia trachomatis","volume":"49","author":"Kutlin","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.intimp.2013.04.027_bb0030","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1128\/AAC.48.4.1402-1405.2004","article-title":"First-choice antibiotics at subinhibitory concentrations induce persistence of Chlamydia pneumoniae","volume":"48","author":"Gieffers","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.intimp.2013.04.027_bb0035","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.1016\/j.vaccine.2010.04.114","article-title":"Evidence of Chlamydophila abortus vaccine strain 1B as a possible cause of ovine enzootic abortion","volume":"28","author":"Wheelhouse","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.intimp.2013.04.027_bb0040","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1146\/annurev.immunol.18.1.927","article-title":"DNA vaccines: immunology, application, and optimization*","volume":"18","author":"Gurunathan","year":"2000","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0045","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1099\/jmm.0.04983-0","article-title":"Evaluation of protection against Chlamydophila abortus challenge after DNA immunization with the major outer-membrane protein-encoding gene in pregnant and non-pregnant mice","volume":"52","author":"Hechard","year":"2003","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0050","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1863-2378.2008.01160.x","article-title":"Induction of a protective immune response against swine Chlamydophila abortus infection in mice following co-vaccination of omp-1 DNA with recombinant MOMP","volume":"56","author":"Zhang","year":"2009","journal-title":"Zoonoses Public Health"},{"key":"10.1016\/j.intimp.2013.04.027_bb0055","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0928-8244(03)00344-4","article-title":"Bacteriophage-mediated nucleic acid immunisation","volume":"40","author":"Clark","year":"2004","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0060","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1016\/j.vaccine.2003.10.047","article-title":"Genetic immunisation against hepatitis B using whole bacteriophage lambda particles","volume":"22","author":"March","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.intimp.2013.04.027_bb0065","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1574-695X.2010.00763.x","article-title":"Comparison of a bacteriophage-delivered DNA vaccine and a commercially available recombinant protein vaccine against hepatitis B","volume":"61","author":"Clark","year":"2011","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0070","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1016\/j.vaccine.2003.11.065","article-title":"Bacteriophage lambda is a highly stable DNA vaccine delivery vehicle","volume":"22","author":"Jepson","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.intimp.2013.04.027_bb0075","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.vetimm.2011.08.003","article-title":"Protection of mice against Chlamydophila abortus infection with a bacteriophage-mediated DNA vaccine expressing the major outer membrane protein","volume":"144","author":"Ling","year":"2011","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0080","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/0076-6879(91)04014-F","article-title":"Special uses of lambda phage for molecular cloning","volume":"204","author":"Murray","year":"1991","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0085","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.vetimm.2003.12.009","article-title":"Recombinant bacteriophage-based multiepitope vaccine against Taenia solium pig cysticercosis","volume":"99","author":"Manoutcharian","year":"2004","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0090","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0165-2427(01)00259-8","article-title":"Comparative evaluation of the CD4+CD8+ and CD4+CD8- lymphocytes in the immune response to porcine rubulavirus","volume":"79","author":"Hernandez","year":"2001","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0095","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1099\/jmm.0.05359-0","article-title":"Differences in lymphocyte subpopulations and cell counts before and after experimentally induced swine dysentery","volume":"53","author":"Jonasson","year":"2004","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0100","doi-asserted-by":"crossref","first-page":"3074","DOI":"10.1128\/IAI.68.6.3074-3078.2000","article-title":"Priming with Chlamydia trachomatis major outer membrane protein (MOMP) DNA followed by MOMP ISCOM boosting enhances protection and is associated with increased immunoglobulin A and Th1 cellular immune responses","volume":"68","author":"Dong-Ji","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.intimp.2013.04.027_bb0105","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1177\/014107680109400605","article-title":"Chlamydial infection in sheep: immune control versus fetal pathology","volume":"94","author":"Entrican","year":"2001","journal-title":"J. R. Soc. Med."},{"key":"10.1016\/j.intimp.2013.04.027_bb0110","doi-asserted-by":"crossref","first-page":"4509","DOI":"10.1016\/j.vaccine.2005.04.014","article-title":"Protection of turkeys against Chlamydophila psittaci challenge by DNA and rMOMP vaccination and evaluation of the immunomodulating effect of 1 alpha,25-dihydroxyvitamin D(3)","volume":"23","author":"Verminnen","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.intimp.2013.04.027_bb0115","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1016\/j.vaccine.2012.02.044","article-title":"Protection of pigs against genital Chlamydia trachomatis challenge by parenteral or mucosal DNA immunization","volume":"30","author":"Schautteet","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.intimp.2013.04.027_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/08820139.2010.504803","article-title":"Co-administration of the polysaccharide of Lycium barbarum with DNA vaccine of Chlamydophila abortus augments protection","volume":"40","author":"Ling","year":"2011","journal-title":"Immunol. Invest."},{"key":"10.1016\/j.intimp.2013.04.027_bb0125","doi-asserted-by":"crossref","first-page":"6595","DOI":"10.1016\/j.vaccine.2009.08.019","article-title":"Immunogenicity of bacteriophage lambda particles displaying porcine Circovirus 2 (PCV2) capsid protein epitopes","volume":"27","author":"Gamage","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.intimp.2013.04.027_bb0130","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1755-8794-5-55","article-title":"Completion of the swine genome will simplify the production of swine as a large animal biomedical model","volume":"5","author":"Walters","year":"2012","journal-title":"BMC Med. Genomics"},{"key":"10.1016\/j.intimp.2013.04.027_bb0135","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.1128\/IAI.63.12.4661-4668.1995","article-title":"Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection","volume":"63","author":"Morrison","year":"1995","journal-title":"Infect. Immun."},{"key":"10.1016\/j.intimp.2013.04.027_bb0140","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.jcpa.2005.12.002","article-title":"Relative importance of CD4+ and CD8+ T cells in the resolution of Chlamydophila abortus primary infection in mice","volume":"134","author":"Martinez","year":"2006","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0145","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1128\/IAI.63.2.516-521.1995","article-title":"Role of CD8 T cells in primary Chlamydia infection","volume":"63","author":"Magee","year":"1995","journal-title":"Infect. Immun."},{"key":"10.1016\/j.intimp.2013.04.027_bb0150","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1073\/pnas.98.3.1160","article-title":"CD8+ T cells recognize an inclusion membrane-associated protein from the vacuolar pathogen Chlamydia trachomatis","volume":"98","author":"Fling","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.intimp.2013.04.027_bb0155","doi-asserted-by":"crossref","first-page":"4742","DOI":"10.4049\/jimmunol.171.9.4742","article-title":"An inclusion membrane protein from Chlamydia trachomatis enters the MHC class I pathway and stimulates a CD8+ T cell response","volume":"171","author":"Starnbach","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0160","first-page":"1","article-title":"Primary human T-cell responses to the major outer membrane protein of Chlamydia trachomatis","volume":"79","author":"Stagg","year":"1993","journal-title":"Immunology"},{"key":"10.1016\/j.intimp.2013.04.027_bb0165","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.4049\/jimmunol.170.4.1659","article-title":"A unique population of extrathymically derived alpha beta TCR+CD4-CD8- T cells with regulatory functions dominates the mouse female genital tract","volume":"170","author":"Johansson","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2013.04.027_bb0170","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.vetimm.2006.03.011","article-title":"P.V. Barnett.Porcine gammadelta T cells: possible roles on the innate and adaptive immune responses following virus infection","volume":"112","author":"Takamatsu","year":"2006","journal-title":"Vet. Immunol. Immunopathol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576913001732?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576913001732?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,26]],"date-time":"2020-07-26T15:56:12Z","timestamp":1595778972000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576913001732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S1567576913001732"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2013.04.027","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of an ompA-based phage-mediated DNA vaccine against Chlamydia abortus in piglets","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2013.04.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}