{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T17:32:21Z","timestamp":1769275941683,"version":"3.49.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"1","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.intimp.2013.12.029","type":"journal-article","created":{"date-parts":[[2014,1,14]],"date-time":"2014-01-14T01:30:13Z","timestamp":1389663013000},"page":"153-160","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Fluticasone furoate is more effective than mometasone furoate in restoring tobacco smoke inhibited SOCS-3 expression in airway epithelial cells"],"prefix":"10.1016","volume":"19","author":[{"given":"Najmunnisa","family":"Nasreen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lixandra","family":"Gonzalves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sriram","family":"Peruvemba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamal A.","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2013.12.029_bb0005","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1165\/ajrcmb.20.4.3265","article-title":"Inhibition of VCAM-1 expression in human bronchial epithelial cells by glucocorticoids","volume":"20","author":"Atsuta","year":"1999","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0010","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.iac.2005.05.003","article-title":"Molecular mechanisms and cellular effects of glucocorticosteroids","volume":"25","author":"Barnes","year":"2005","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.intimp.2013.12.029_bb0015","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0014-5793(00)02297-3","article-title":"The glucocorticoid receptor and STAT6 physically and functionally interact in T-lymphocytes","volume":"487","author":"Biola","year":"2000","journal-title":"FEBS Lett"},{"key":"10.1016\/j.intimp.2013.12.029_bb0020","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0014-5793(99)01662-2","article-title":"LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages","volume":"463","author":"Bode","year":"1999","journal-title":"FEBS Lett"},{"key":"10.1016\/j.intimp.2013.12.029_bb0025","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.4049\/jimmunol.177.7.4350","article-title":"Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice","volume":"177","author":"Bracke","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0030","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/1465-9921-9-73","article-title":"One-year treatment with mometasone furoate in chronic obstructive pulmonary disease","volume":"9","author":"Calverley","year":"2008","journal-title":"Respir Res"},{"key":"10.1016\/j.intimp.2013.12.029_bb0035","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/S0140-6736(03)14416-9","article-title":"Chronic obstructive pulmonary disease","volume":"362","author":"Calverley","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.intimp.2013.12.029_bb0040","first-page":"388","article-title":"Comparison of the effects of two long-acting beta2-agonists on cytokine secretion by human airway epithelial cells","volume":"40","author":"Chiu","year":"2007","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.intimp.2013.12.029_bb0045","doi-asserted-by":"crossref","first-page":"7082","DOI":"10.4049\/jimmunol.166.12.7082","article-title":"Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs","volume":"166","author":"Dalpke","year":"2001","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0050","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1183\/09031936.03.00031803","article-title":"Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-beta kinase pathway","volume":"21","author":"Escotte","year":"2003","journal-title":"Eur Respir J"},{"key":"10.1016\/j.intimp.2013.12.029_bb0055","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cyto.2005.02.006","article-title":"Serum surfactant protein D is increased in acute and chronic inflammation in mice","volume":"31","author":"Fujita","year":"2005","journal-title":"Cytokine"},{"key":"10.1016\/j.intimp.2013.12.029_bb0060","doi-asserted-by":"crossref","first-page":"6969","DOI":"10.4049\/jimmunol.172.11.6969","article-title":"Suppressors of cytokine signaling regulate Fc receptor signaling and cell activation during immune renal injury","volume":"172","author":"Gomez-Guerrero","year":"2004","journal-title":"J Immunol"},{"issue":"Suppl. B","key":"10.1016\/j.intimp.2013.12.029_bb0065","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1016\/S1096-6374(00)80004-0","article-title":"Regulation of the trans-activation potential of STAT5 through its DNA-binding activity and interactions with heterologous transcription factors","volume":"10","author":"Groner","year":"2000","journal-title":"Growth Horm IGF Res"},{"key":"10.1016\/j.intimp.2013.12.029_bb0070","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1038\/nm1269","article-title":"Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis","volume":"11","author":"Jo","year":"2005","journal-title":"Nat Med"},{"key":"10.1016\/j.intimp.2013.12.029_bb0075","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1002\/j.1460-2075.1992.tb05283.x","article-title":"Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo","volume":"11","author":"Konig","year":"1992","journal-title":"EMBO J"},{"key":"10.1016\/j.intimp.2013.12.029_bb0080","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1146\/annurev.immunol.16.1.293","article-title":"Jaks and STATs: biological implications","volume":"16","author":"Leonard","year":"1998","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0085","doi-asserted-by":"crossref","first-page":"e000370","DOI":"10.1136\/bmjopen-2011-000370","article-title":"Efficacy and safety of 4 weeks' treatment with combined fluticasone furoate\/vilanterol in a single inhaler given once daily in COPD: a placebo-controlled randomised trial","volume":"2","author":"Lotvall","year":"2012","journal-title":"BMJ open"},{"key":"10.1016\/j.intimp.2013.12.029_bb0090","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0092-8674(00)80049-5","article-title":"SOCS3 is essential in the regulation of fetal liver erythropoiesis","volume":"98","author":"Marine","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.intimp.2013.12.029_bb0095","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1378\/chest.122.6.2003","article-title":"Characteristics of adults dying with COPD","volume":"122","author":"Meyer","year":"2002","journal-title":"Chest"},{"key":"10.1016\/j.intimp.2013.12.029_bb0100","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1080\/01902140290096728","article-title":"A murine model of cigarette smoke-induced pulmonary inflammation using intranasally administered smoke-conditioned medium","volume":"28","author":"Miller","year":"2002","journal-title":"Exp Lung Res"},{"key":"10.1016\/j.intimp.2013.12.029_bb0105","first-page":"L559","article-title":"Cyclic stretch induces PlGF expression in bronchial airway epithelial cells via nitric oxide release","volume":"292","author":"Mohammed","year":"2007","journal-title":"Am J Physiol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0110","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.intimp.2011.11.014","article-title":"Fluticasone propionate and salmeterol combination induces SOCS-3 expression in airway epithelial cells","volume":"12","author":"Nasreen","year":"2012","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0115","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1002\/cncr.22254","article-title":"Silencing the receptor EphA2 suppresses the growth and haptotaxis of malignant mesothelioma cells","volume":"107","author":"Nasreen","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.intimp.2013.12.029_bb0120","doi-asserted-by":"crossref","first-page":"L115","DOI":"10.1152\/ajplung.90587.2008","article-title":"Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-beta1 in vitro","volume":"297","author":"Nasreen","year":"2009","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0125","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1086\/315057","article-title":"Mycobacterium-induced transmesothelial migration of monocytes into pleural space: role of intercellular adhesion molecule-1 in tuberculous pleurisy","volume":"180","author":"Nasreen","year":"1999","journal-title":"J Infect Dis"},{"key":"10.1016\/j.intimp.2013.12.029_bb0130","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1164\/ajrccm.163.5.2101039","article-title":"Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI\/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary","volume":"163","author":"Pauwels","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.intimp.2013.12.029_bb0135","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1046\/j.1471-4159.2002.01208.x","article-title":"Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia","volume":"83","author":"Raghavendra Rao","year":"2002","journal-title":"J Neurochem"},{"key":"10.1016\/j.intimp.2013.12.029_bb0140","doi-asserted-by":"crossref","first-page":"139S","DOI":"10.1378\/chest.107.3_Supplement.139S","article-title":"Anti-inflammation: direct physical association and functional antagonism between transcription factor NF-KB and the glucocorticoid receptor","volume":"107","author":"Ray","year":"1995","journal-title":"Chest"},{"key":"10.1016\/j.intimp.2013.12.029_bb0145","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1164\/ajrccm.160.supplement_1.5","article-title":"Inflammation and repair processes in chronic obstructive pulmonary disease","volume":"160","author":"Rennard","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.intimp.2013.12.029_bb0150","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.ejphar.2011.08.022","article-title":"Long-acting fluticasone furoate has a superior pharmacological profile to fluticasone propionate in human respiratory cells","volume":"670","author":"Rossios","year":"2011","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0155","first-page":"L660","article-title":"Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease","volume":"293","author":"Salter","year":"2007","journal-title":"Am J Physiol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0160","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1172\/JCI13568","article-title":"Induction of the cytokine signal regulator SOCS3\/CIS3 as a therapeutic strategy for treating inflammatory arthritis","volume":"108","author":"Shouda","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1016\/j.intimp.2013.12.029_bb0165","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/43206","article-title":"A family of cytokine-inducible inhibitors of signalling","volume":"387","author":"Starr","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2013.12.029_bb0170","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S0091-6749(99)70334-9","article-title":"An in vitro comparison of commonly used topical glucocorticoid preparations","volume":"104","author":"Stellato","year":"1999","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0175","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S0091-6749(03)02011-6","article-title":"Airway inflammation in chronic obstructive pulmonary disease: comparisons with asthma","volume":"112","author":"Sutherland","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0180","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1161\/ATVBAHA.110.207464","article-title":"Suppressors of cytokine signaling (SOCS) proteins and JAK\/STAT pathways: regulation of T-cell inflammation by SOCS1 and SOCS3","volume":"31","author":"Tamiya","year":"2011","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0185","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0091-6749(97)70144-1","article-title":"The inhibitory effects of topically active glucocorticoids on IL-4, IL-5, and interferon-gamma production by cultured primary CD4+ T cells","volume":"100","author":"Umland","year":"1997","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0190","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1164\/rccm.200408-1041OC","article-title":"Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy","volume":"172","author":"Usmani","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.intimp.2013.12.029_bb0195","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1465-9921-8-54","article-title":"Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoate","volume":"8","author":"Valotis","year":"2007","journal-title":"Respir Res"},{"key":"10.1016\/j.intimp.2013.12.029_bb0200","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1007\/s10875-006-9029-z","article-title":"Glucocorticoids increase repair potential in a novel in vitro human airway epithelial wounding model","volume":"26","author":"Wadsworth","year":"2006","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.intimp.2013.12.029_bb0205","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1172\/JCI13939","article-title":"Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways","volume":"108","author":"Yasukawa","year":"2001","journal-title":"J Clin Invest"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576914000022?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576914000022?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T12:42:45Z","timestamp":1565095365000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576914000022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["S1567576914000022"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2013.12.029","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fluticasone furoate is more effective than mometasone furoate in restoring tobacco smoke inhibited SOCS-3 expression in airway epithelial cells","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2013.12.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}