{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:59:25Z","timestamp":1788872365084,"version":"build-2803163510"},"reference-count":43,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Council of Scientific and Industrial Research (CSIR), New Delhi","award":["0111"],"award-info":[{"award-number":["0111"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.intimp.2014.08.016","type":"journal-article","created":{"date-parts":[[2014,9,6]],"date-time":"2014-09-06T19:15:38Z","timestamp":1410030938000},"page":"92-103","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Allergic manifestation by black gram (Vigna mungo) proteins in allergic patients, BALB\/c mice and RBL-2H3 cells"],"prefix":"10.1016","volume":"23","author":[{"given":"Alok Kumar","family":"Verma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akanksha","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchi","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinkesh Kumar","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhushan P.","family":"Chaudhari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.H.","family":"Giridhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukul","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Premendra D.","family":"Dwivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2014.08.016_bb0005","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.intimp.2012.05.018","article-title":"Molecular mechanism of IgE mediated food allergy","volume":"13","author":"Kumar","year":"2012","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s12016-012-8310-6","article-title":"A comprehensive review of legume allergy","volume":"45","author":"Verma","year":"2013","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0015","article-title":"Nutritive value of Indian foods","author":"Gopalan","year":"1989"},{"key":"10.1016\/j.intimp.2014.08.016_bb0020","first-page":"240","article-title":"Black gram (Vigna mungo) \u2014 a hypolipidemic pulse","volume":"2","author":"Indira","year":"2003","journal-title":"Nat Prod Rad"},{"key":"10.1016\/j.intimp.2014.08.016_bb0025","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1034\/j.1398-9995.2002.1s3412.x","article-title":"Food allergy is a matter of geography after all, sesame as a major cause of severe IgE-mediated food allergic reactions among infants and young children in Israel","volume":"57","author":"Dalal","year":"2002","journal-title":"Allergy"},{"key":"10.1016\/j.intimp.2014.08.016_bb0030","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1398-9995.2006.00990.x","article-title":"Sensitization to black gram in patients with bronchial asthma and rhinitis, clinical evaluation and characterization of allergens","volume":"61","author":"Kumari","year":"2006","journal-title":"Allergy"},{"key":"10.1016\/j.intimp.2014.08.016_bb0035","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.imbio.2011.12.011","article-title":"Isolation and characterization of a 28kDa major allergen from black gram (Phaseolus mungo)","volume":"217","author":"Kumari","year":"2012","journal-title":"Immunobiology"},{"key":"10.1016\/j.intimp.2014.08.016_bb0040","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1016\/j.fct.2010.06.047","article-title":"Partial characterization of red gram (Cajanus cajan L. Millsp.) polypeptides recognized by patients exhibiting rhinitis and bronchial asthma","volume":"48","author":"Misra","year":"2010","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0045","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1038\/nbt1096-1269","article-title":"Stability of food allergens to digestion in vitro","volume":"14","author":"Astwood","year":"1996","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0050","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1080\/08923970802578782","article-title":"Probing novel allergenic proteins of commonly consumed legumes","volume":"31","author":"Misra","year":"2009","journal-title":"Immunopharmacol Immunotoxicol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0055","article-title":"Protocols for food and feed safety assessment of GE crops","author":"DBT","year":"2008"},{"key":"10.1016\/j.intimp.2014.08.016_bb0060","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets","volume":"76","author":"Towbin","year":"1979","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.intimp.2014.08.016_bb0065","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1016\/j.foodres.2011.06.043","article-title":"Allergenic responses of red kidney bean (Phaseolus vulgaris cv. chitra) polypeptides in BALB\/c mice recognized by bronchial asthma and allergic rhinitis patients","volume":"44","author":"Kumar","year":"2011","journal-title":"Food Res Int"},{"key":"10.1016\/j.intimp.2014.08.016_bb0070","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1111\/j.1365-2222.2011.03780.x","article-title":"Potential allergens of green gram (Vigna radiata L. Millsp.) identified as members of cupin superfamily and seed albumin","volume":"41","author":"Misra","year":"2011","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.intimp.2014.08.016_bb0075","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/j.1398-9995.1998.tb03967.x","article-title":"Peanut allergens","volume":"53","author":"Burks","year":"1998","journal-title":"Allergy"},{"key":"10.1016\/j.intimp.2014.08.016_bb0080","first-page":"220","article-title":"Peanuts: allergic and other untoward reactions","volume":"48","author":"Fries","year":"1982","journal-title":"Ann Allergy"},{"key":"10.1016\/j.intimp.2014.08.016_bb0085","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/toxsci\/kfi187","article-title":"The effect of the food matrix on in vivo immune responses to purified peanut allergens","volume":"86","author":"Van Wijk","year":"2005","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.intimp.2014.08.016_bb0090","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.toxlet.2012.01.011","article-title":"Chickpea (Cicer arietinum) proteins induce allergic responses in nasobronchial allergic patients and BALB\/c mice","volume":"210","author":"Verma","year":"2012","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.intimp.2014.08.016_bb0095","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0091-6749(99)70492-6","article-title":"A murine model of IgE-mediated cow's milk hypersensitivity","volume":"103","author":"Li","year":"1999","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0100","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.intimp.2014.01.014","article-title":"Phaseolin: A 47.5kDa protein of red kidney bean (Phaseolus vulgaris L.) plays a pivotal role in hypersensitivity induction","volume":"19","author":"Kumar","year":"2014","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0105","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.foodres.2014.01.035","article-title":"Allergenic responses of green gram (Vigna radiata L. Millsp.) proteins can be vitiated by induction of oral tolerance due to single acute dose in BALB\/c mice","volume":"57","author":"Kumar","year":"2014","journal-title":"Food Res Int"},{"key":"10.1016\/j.intimp.2014.08.016_bb0110","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.nut.2013.11.024","article-title":"Hypersensitivity linked to exposure of broad bean protein(s) in allergic patients and BALB\/c mice","volume":"30","author":"Kumar","year":"2014","journal-title":"Nutrition"},{"key":"10.1016\/j.intimp.2014.08.016_bb0115","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.nut.2012.11.010","article-title":"Clinical complications of kidney bean (Phaseolus vulgaris L.) consumption","volume":"29","author":"Kumar","year":"2013","journal-title":"Nutrition"},{"key":"10.1016\/j.intimp.2014.08.016_bb0120","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/0091-6749(92)90461-A","article-title":"Allergenicity of peanut and soybean extracts altered by chemical or thermal denaturation in patients with atopic dermatitis and positive food challenges","volume":"90","author":"Burks","year":"1992","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0125","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.yrtph.2003.11.003","article-title":"A multi-laboratory evaluation of a common in vitro pepsin digestion assay protocol used in assessing the safety of novel proteins","volume":"39","author":"Thomas","year":"2004","journal-title":"Regul Toxicol Pharmacol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0130","doi-asserted-by":"crossref","first-page":"3271","DOI":"10.1021\/jf060169h","article-title":"Quillaja saponin can modulate ovalbumin-induced IgE allergic responses through regulation of Th1\/Th2 balance in a murine model","volume":"54","author":"Katayama","year":"2006","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.intimp.2014.08.016_bb0135","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.imlet.2011.10.010","article-title":"Establishment and characterization of a murine model for allergic asthma using allergen-specific IgE monoclonal antibody to study pathological roles of IgE","volume":"141","author":"Mizutani","year":"2012","journal-title":"Immunol Lett"},{"key":"10.1016\/j.intimp.2014.08.016_bb0140","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1093\/intimm\/dxg049","article-title":"Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid","volume":"15","author":"Cribbs","year":"2003","journal-title":"Int Immunol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0145","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1146\/annurev.iy.08.040190.001511","article-title":"Lymphokine control of in vivo immunoglobulin isotype selection","volume":"8","author":"Finkelman","year":"1990","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0150","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1046\/j.1440-1711.2003.01155.x","article-title":"A prolonged immune response to antigen delivered in poly (set symbol-caprolactone) microparticles","volume":"81","author":"Slobbe","year":"2003","journal-title":"Immunol Cell Biol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0155","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1365-2222.1991.tb01658.x","article-title":"The high affinity receptor for IgE on mast cells","volume":"21","author":"Metzger","year":"1991","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.intimp.2014.08.016_bb0160","doi-asserted-by":"crossref","first-page":"17","DOI":"10.2165\/00003495-199958004-00003","article-title":"Inhaled corticosteroid therapy in newly detected mild asthma","volume":"58","author":"O'Byrne","year":"1999","journal-title":"Drugs"},{"key":"10.1016\/j.intimp.2014.08.016_bb0165","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1136\/gut.2003.023671","article-title":"Modulating the intestinal immune system: the role of lymphotoxin and GALT organs","volume":"53","author":"Spahn","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.intimp.2014.08.016_bb0170","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.jaci.2010.04.003","article-title":"Targeting Toll-like receptors on dendritic cells modifies the T(H)2 response to peanut allergens in vitro","volume":"126","author":"Pochard","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0175","doi-asserted-by":"crossref","first-page":"7716","DOI":"10.4049\/jimmunol.174.12.7716","article-title":"IgE generation and mast cell effector function in mice deficient in IL-4 and IL-13","volume":"174","author":"Fish","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0180","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1164\/rccm.200601-079OC","article-title":"Transcription factors T-bet and GATA-3 regulate development of airway remodeling","volume":"174","author":"Kiwamoto","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.intimp.2014.08.016_bb0185","doi-asserted-by":"crossref","first-page":"26983","DOI":"10.1074\/jbc.M403688200","article-title":"Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci","volume":"279","author":"Yamashita","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.intimp.2014.08.016_bb0190","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1111\/j.1440-1711.2006.01452.x","article-title":"Concurrent exposure to thermal stress and oral Ag induces intestinal sensitization in the mouse by a mechanism of regulation of IL-12 expression","volume":"84","author":"Liu","year":"2006","journal-title":"Immunol Cell Biol"},{"key":"10.1016\/j.intimp.2014.08.016_bb0195","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/s00011-009-0074-y","article-title":"The RBL-2H3 cell line: its provenance and suitability as a model for the mast cell","volume":"58","author":"Passante","year":"2009","journal-title":"Inflamm Res"},{"key":"10.1016\/j.intimp.2014.08.016_bb0200","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1002\/mnfr.200500073","article-title":"Allergenic characteristics of a modified peanut allergen","volume":"49","author":"King","year":"2005","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.intimp.2014.08.016_bb0205","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1600-065X.2011.01028.x","article-title":"Anaphylaxis: a history with emphasis on food allergy","volume":"242","author":"Boden","year":"2011","journal-title":"Immunol Rev"},{"key":"10.1016\/j.intimp.2014.08.016_bb0210","first-page":"93","article-title":"The two faces of mast cells in food allergy and allergic asthma: the possible concept of Yin Yang","volume":"2012","author":"Kraneveld","year":"1822","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.intimp.2014.08.016_bb0215","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jprot.2013.02.003","article-title":"Phytohemagglutinins augment red kidney bean (Phaseolus vulgaris L.) induced allergic manifestations","volume":"93","author":"Kumar","year":"2013","journal-title":"J Proteome"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576914003300?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576914003300?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,29]],"date-time":"2018-09-29T20:54:35Z","timestamp":1538254475000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576914003300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S1567576914003300"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2014.08.016","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Allergic manifestation by black gram (Vigna mungo) proteins in allergic patients, BALB\/c mice and RBL-2H3 cells","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2014.08.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}