{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:41:49Z","timestamp":1760550109215},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81270637","81300442","81300377","81300399","81471580"],"award-info":[{"award-number":["81270637","81300442","81300377","81300399","81471580"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20151153"],"award-info":[{"award-number":["BK20151153"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002949","name":"Jiangsu Province","doi-asserted-by":"publisher","award":["BRA2015504"],"award-info":[{"award-number":["BRA2015504"]}],"id":[{"id":"10.13039\/501100002949","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.intimp.2016.08.012","type":"journal-article","created":{"date-parts":[[2016,8,20]],"date-time":"2016-08-20T11:01:18Z","timestamp":1471690878000},"page":"383-388","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["IL-22 promoted CD3 + T cell infiltration by IL-22R induced STAT3 phosphorylation in murine acute graft versus host disease target organs after allogeneic bone marrow transplantation"],"prefix":"10.1016","volume":"39","author":[{"given":"Kai","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhong","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiling","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingling","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengyun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kailin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2016.08.012_bb0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00277-002-0586-9","article-title":"Allogeneic stem cell transplantation after reduced-intensity conditioning in lymphoid malignancies","volume":"82","author":"Sureda","year":"2003","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0010","doi-asserted-by":"crossref","first-page":"4327","DOI":"10.1182\/blood-2009-06-204669","article-title":"Acute graft-versus-host disease: from the bench to the bedside","volume":"114","author":"Socie","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2016.08.012_bb0015","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.trsl.2007.06.003","article-title":"Pathophysiology of acute graft-versus-host disease: recent advances","volume":"150","author":"Sun","year":"2007","journal-title":"Transl. Res."},{"key":"10.1016\/j.intimp.2016.08.012_bb0020","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1038\/leu.2013.39","article-title":"IL-22 deficiency in donor T cells attenuates murine acute graft-versus-host disease mortality while sparing the graft-versus-leukemia effect","volume":"27","author":"Couturier","year":"2013","journal-title":"Leukemia"},{"key":"10.1016\/j.intimp.2016.08.012_bb0025","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.immuni.2012.05.028","article-title":"Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease","volume":"37","author":"Hanash","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.intimp.2016.08.012_bb0030","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/j.imbio.2013.05.005","article-title":"The identification and characteristics of IL-22-producing T cells in acute graft-versus-host disease following allogeneic bone marrow transplantation","volume":"218","author":"Zhao","year":"2013","journal-title":"Immunobiology"},{"key":"10.1016\/j.intimp.2016.08.012_bb0035","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1089\/jir.2013.0099","article-title":"Interleukin-22 aggravates murine acute graft-versus-host disease by expanding effector T cell and reducing regulatory T cell","volume":"34","author":"Zhao","year":"2014","journal-title":"J. Interf. Cytokine Res."},{"key":"10.1016\/j.intimp.2016.08.012_bb0040","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/bjh.13068","article-title":"Interleukin-22 in the diagnosis of active chronic graft-versus-host disease in paediatric patients","volume":"168","author":"Tumino","year":"2015","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0045","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.imlet.2011.12.005","article-title":"Altered balance between Th1 and Th17 cells in circulation is an indicator for the severity of murine acute GVHD","volume":"142","author":"Pan","year":"2012","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.intimp.2016.08.012_bb0050","first-page":"4143","article-title":"Complement membrane attack complex is related with immune-mediated necrotizing myopathy","volume":"7","author":"Cong","year":"2014","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0055","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.cbi.2010.03.035","article-title":"Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells","volume":"185","author":"Zhang","year":"2010","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.intimp.2016.08.012_bb0060","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.1182\/blood-2003-08-2827","article-title":"In vivo imaging of graft-versus-host-disease in mice","volume":"103","author":"Panoskaltsis-Mortari","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2016.08.012_bb0065","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1002\/eji.201344155","article-title":"Altered T-cell entry and egress in the absence of Coronin 1A attenuates murine acute graft versus host disease","volume":"44","author":"Fulton","year":"2014","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0070","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1146\/annurev.immunol.22.012703.104622","article-title":"Interleukin-10 and related cytokines and receptors","volume":"22","author":"Pestka","year":"2004","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0075","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.cytogfr.2006.09.001","article-title":"Interleukin-22: a novel T- and NK-cell derived cytokine that regulates the biology of tissue cells","volume":"17","author":"Wolk","year":"2006","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.intimp.2016.08.012_bb0080","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.immuni.2004.07.007","article-title":"IL-22 increases the innate immunity of tissues","volume":"21","author":"Wolk","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.intimp.2016.08.012_bb0085","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1182\/blood-2005-02-0509","article-title":"In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets","volume":"106","author":"Beilhack","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2016.08.012_bb0090","doi-asserted-by":"crossref","first-page":"4914","DOI":"10.1182\/blood-2009-08-239848","article-title":"Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells","volume":"115","author":"Coghill","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2016.08.012_bb0095","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/nm1710","article-title":"IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia","volume":"14","author":"Aujla","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.intimp.2016.08.012_bb0100","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1038\/jid.2011.468","article-title":"IFN-alpha enhances IL-22 receptor expression in keratinocytes: a possible role in the development of psoriasis","volume":"132","author":"Tohyama","year":"2012","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0105","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1002\/eji.200939473","article-title":"IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression","volume":"39","author":"Tohyama","year":"2009","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0110","doi-asserted-by":"crossref","first-page":"5531","DOI":"10.4049\/jimmunol.0904091","article-title":"IL-22 induces an acute-phase response","volume":"185","author":"Liang","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0115","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.4049\/jimmunol.174.6.3695","article-title":"IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes","volume":"174","author":"Boniface","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2016.08.012_bb0120","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1074\/jbc.M007837200","article-title":"Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes","volume":"276","author":"Kotenko","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2016.08.012_bb0125","doi-asserted-by":"crossref","first-page":"31335","DOI":"10.1074\/jbc.M005304200","article-title":"Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R","volume":"275","author":"Xie","year":"2000","journal-title":"J. Biol. Chem."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576916303290?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576916303290?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T11:11:05Z","timestamp":1601032265000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576916303290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":25,"alternative-id":["S1567576916303290"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2016.08.012","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"IL-22 promoted CD3+ T cell infiltration by IL-22R induced STAT3 phosphorylation in murine acute graft versus host disease target organs after allogeneic bone marrow transplantation","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2016.08.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}