{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T04:29:38Z","timestamp":1772771378358,"version":"3.50.1"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.intimp.2017.07.004","type":"journal-article","created":{"date-parts":[[2017,7,12]],"date-time":"2017-07-12T01:15:29Z","timestamp":1499822129000},"page":"243-250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Carvedilol can attenuate histamine-induced paw edema and formaldehyde-induced arthritis in rats without risk of gastric irritation"],"prefix":"10.1016","volume":"50","author":[{"given":"Afaf Sayed","family":"Osman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina Ahmed","family":"Labib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud M.","family":"Kamel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0005","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1046\/j.1365-2036.1996.719899000.x","article-title":"Gastrointestinal tolerability of lornoxicam compared to that of naproxen in healthy male volunteers","volume":"10","author":"Aabakken","year":"1996","journal-title":"Aliment. Pharmacol. Ther."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0010","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1006\/taap.2000.8985","article-title":"Effects of captopril on interleukin-6, leukotriene B4, and oxidative stress markers in serum and inflammatory exudate of arthritic rats: evidence of antiinflammatory activity","volume":"168","author":"Agha","year":"2000","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0015","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3923\/ijp.2009.146.154","article-title":"Inhibition of ethanol-induced gastric mucosal damage by Carvedilol in male Wistar albino rats: possible biochemical changes","volume":"5","author":"Al-Rejaie","year":"2009","journal-title":"Int. J. Pharmacol."},{"key":"10.1016\/j.intimp.2017.07.004_bb0020","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.cyto.2016.09.004","article-title":"Carvedilol attenuates paraquat-induced lung injury by inhibition of proinflammatory cytokines, chemokine MCP-1, NF-\u03baB activation and oxidative stress mediators","volume":"88","author":"Amirshahrokhi","year":"2016","journal-title":"Cytokines"},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0025","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.taap.2013.01.019","article-title":"Carvedilol alleviates adjuvant-induced arthritis and subcutaneous air pouch edema: modulation of oxidative stress and inflammatory mediators","volume":"268","author":"Arab","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0030","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1006\/phrs.2001.0921","article-title":"Effects of lornoxicam, piroxicam and meloxicam in a model of thermal hindpaw hyperalgesia induced by formalin injected in rat-tail","volume":"45","author":"Bianchi","year":"2002","journal-title":"Pharmacol. Res."},{"issue":"10","key":"10.1016\/j.intimp.2017.07.004_bb0035","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/ni1001-907","article-title":"Nitric oxide and the immune response","volume":"2","author":"Bogdan","year":"2001","journal-title":"Nat. Immunol."},{"issue":"11","key":"10.1016\/j.intimp.2017.07.004_bb0040","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1172\/JCI36389","article-title":"Evidence that cytokines play a role in rheumatoid arthritis","volume":"118","author":"Brennan","year":"2008","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.intimp.2017.07.004_bb0045","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s10787-997-0030-9","article-title":"Potent anti-inflammatory\/analgesic effects of lornoxicam in comparison to other NSAIDS: a c-Fos study in the rat","volume":"5","author":"Buritova","year":"1997","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.intimp.2017.07.004_bb0050","article-title":"Carvedilol inhibits tumor necrosis factor-\u2013induced endothelial transcription factor activation, adhesion molecule expression, and adhesiveness to human mononuclear cells","volume":"2075-2081","author":"Chen","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5","key":"10.1016\/j.intimp.2017.07.004_bb0055","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.3892\/etm.2016.3140","article-title":"Effects of carvidelol reduce conjunctivitis through changes in inflammation, NGF and VECF levels in a rat model","volume":"11","author":"Chen","year":"2016","journal-title":"Exp. Ther. Med."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0060","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1113\/jphysiol.2001.013473","article-title":"Pathophysiological basis of acute inflammatory hyperaemia in the rat knee: roles of cyclo-oxygenase-1 and -2","volume":"539","author":"Colin","year":"2002","journal-title":"J. Physiol."},{"issue":"4","key":"10.1016\/j.intimp.2017.07.004_bb0065","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1097\/HJH.0b013e3280127948","article-title":"Antioxidant activity of carvedilol in cardiovascular disease","volume":"25","author":"Dandona","year":"2007","journal-title":"J. Hypertens."},{"issue":"10","key":"10.1016\/j.intimp.2017.07.004_bb0070","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1136\/hrt.2006.097816","article-title":"The autoantibody rheumatoid factor may be an independent risk factor for ischaemic heart disease in men","volume":"93","author":"Edwards","year":"2007","journal-title":"Heart"},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0075","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ejphar.2007.02.036","article-title":"Carvedilol ameliorates endothelial dysfunction in streptozotocin-induced diabetic rats","volume":"567","author":"Fu","year":"2007","journal-title":"Eur. J. Pharmacol."},{"issue":"Suppl. 2","key":"10.1016\/j.intimp.2017.07.004_bb0080","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1440-1746.2011.07003.x","article-title":"Hepatoprotective and anti-inflammatory cytokines in alcoholic liver disease","volume":"27","author":"Gao","year":"2012","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"30","key":"10.1016\/j.intimp.2017.07.004_bb0085","first-page":"3287","article-title":"Morphological evaluation of ethylic damage on gastric mucosal repair after surgery","volume":"46","author":"Giovanoni","year":"1999","journal-title":"Hepato-Gastroenterology"},{"issue":"11","key":"10.1016\/j.intimp.2017.07.004_bb0090","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.1002\/art.22979","article-title":"The widening mortality gap between rheumatoid arthritis patients and the general population","volume":"56","author":"Gonzalez","year":"2007","journal-title":"Arthritis Rheum."},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0095","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.taap.2012.04.012","article-title":"New therapeutic aspect for carvedilol: antifibrotic effects of carvedilol in chronic carbon tetrachloride-induced liver damage","volume":"261","author":"Hamdy","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"6","key":"10.1016\/j.intimp.2017.07.004_bb0100","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/ar1447","article-title":"Oxidation in rheumatoid arthritis","volume":"6","author":"Hitchon","year":"2004","journal-title":"Arthritis Res. Ther."},{"issue":"5","key":"10.1016\/j.intimp.2017.07.004_bb0105","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s10353-006-0272-6","article-title":"Xefo\u00ae rapid: a novel effective tool for pain treatment","volume":"38","author":"Homdrum","year":"2006","journal-title":"Eur. Surg."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0110","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1084\/jem.20051310","article-title":"Prostacyclin-IP signaling and prostaglandin E2-EP2\/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis","volume":"203","author":"Honda","year":"2006","journal-title":"J. Exp. Med."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0115","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.diabres.2006.04.016","article-title":"Carvedilol improved diabetic rat cardiac function depending on antioxidant ability","volume":"75","author":"Huang","year":"2007","journal-title":"Diabetes Res. Clin. Pract."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0120","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0378-8741(00)00398-6","article-title":"Evaluation of the gastric antiulcerogenic effect of large cardamom (fruits of Amomum subulatum Roxb)","volume":"75","author":"Jafri","year":"2001","journal-title":"J. Ethanopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0125","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0014-2999(96)00705-4","article-title":"A mechanistic study of beta-adrenoceptor antagonists on ethanol-induced gastric damage","volume":"317","author":"Kaan","year":"1996","journal-title":"Eur. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0130","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.rdc.2010.02.002","article-title":"Cardiovascular complications of rheumatoid arthritis - assessment, prevention and treatment","volume":"36","author":"Kaplan","year":"2010","journal-title":"Rheum. Dis. Clin. N. Am."},{"issue":"8","key":"10.1016\/j.intimp.2017.07.004_bb0135","first-page":"4471","article-title":"Design, development and evaluation of Lornoxicam sustained release tablet using 32 factorial design","volume":"5","author":"Karna","year":"2012","journal-title":"J. Pharm. Res."},{"issue":"8","key":"10.1016\/j.intimp.2017.07.004_bb0140","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1016\/j.fct.2012.05.016","article-title":"Evaluation of antiarthritic activity of isoeugenol in adjuvant induced arthritis in murine model","volume":"50","author":"Kaur","year":"2012","journal-title":"Food Chem. Toxicol."},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0145","first-page":"219","article-title":"Unilateral central retinal artery occlusion followed by contralateral anterior ischemic optic neuropathy","volume":"50","author":"Khosla","year":"2004","journal-title":"J. Postgrad. Med."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0150","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.pbb.2008.10.005","article-title":"Neuroprotective effect of carvedilol, an adrenergic antagonist against colchicine induced cognitive impairment and oxidative damage in rat","volume":"92","author":"Kumar","year":"2009","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0155","first-page":"54","article-title":"Antiarthrtic property of methanolic extract of Syzygium cumini seeds","volume":"1","author":"Kumar","year":"2008","journal-title":"J. Biomed. Sci."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0160","first-page":"29","article-title":"The efficacy of aqueous and ethanolic leaf extracts of Pistia stratiotes linn in the management of arthritis and fever","volume":"1","author":"Kyei","year":"2012","journal-title":"J. Med. Biomed. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0165","first-page":"112","article-title":"Carvedilol treatment ameliorates acute coxsackievirus B3-induced myocarditis associated with oxidative stress reduction","volume":"640","author":"Li","year":"2010","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0170","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/ar2376","article-title":"Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase- 13","volume":"10","author":"Long","year":"2008","journal-title":"Arthritis Res. Ther."},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0175","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0049-0172(03)00134-3","article-title":"Cyclooxygenase-2 and prostaglandins in articular tissues","volume":"33","author":"Martel-Pelletier","year":"2003","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.intimp.2017.07.004_bb0180","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0006-2952(01)00651-7","article-title":"Radicalscavenging and iron-chelating properties of carvedilol, an antihypertensive drug with antioxidative activity","volume":"62","author":"Oettl","year":"2001","journal-title":"Biochem. Pharmacol."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0185","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.taap.2004.04.005","article-title":"Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity","volume":"200","author":"Oliveira","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0190","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0149-7634(86)90017-5","article-title":"Restraint stress in biomedical research: a review","volume":"10","author":"Par\u00e9","year":"1986","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0195","first-page":"371","article-title":"Comparison of the effects of repeated dose treatment of lornorxicam and meloxicam on renal functions in rats","volume":"40","author":"Pehlivan","year":"2010","journal-title":"Turk. J. Med. Sci."},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0200","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/S0022-3565(25)11144-0","article-title":"Reduction of aspirin induced gastric damage in rats by interleukin-1B; possible involvement of endogenous corticosteroids","volume":"261","author":"Perretti","year":"1992","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"6","key":"10.1016\/j.intimp.2017.07.004_bb0205","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1089\/ars.2009.2607","article-title":"Aberrant reactive oxygen and nitrogen species generation in rheumatoid arthritis (RA): causes and consequences for immune function, cell survival, and therapeutic intervention","volume":"12","author":"Phillips","year":"2010","journal-title":"Antioxid. Redox Signal."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0210","first-page":"27","article-title":"Lornoxicam: a newer NSAID","volume":"20","author":"Prasad","year":"2009","journal-title":"Ind. J. Phys. Med. Rehabil."},{"key":"10.1016\/j.intimp.2017.07.004_bb0215","first-page":"490","article-title":"Compendium of Indian medicinal plants","volume":"4","author":"Rastogi","year":"1995","journal-title":"CSIR"},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0220","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.mito.2009.09.001","article-title":"Carvedilol protects against the renal mitochondrial toxicity induced by cisplatin in rats","volume":"10","author":"Rodrigues","year":"2010","journal-title":"Mitochondrion"},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0225","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1179\/135100005X38879","article-title":"Cytoprotective effects of carvedilol against oxygen free radical generation in rat liver","volume":"10","author":"Ronsein","year":"2005","journal-title":"Redox Rep."},{"issue":"7","key":"10.1016\/j.intimp.2017.07.004_bb0230","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1136\/gut.35.7.909","article-title":"Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumor necrosis factor alpha","volume":"35","author":"Santucci","year":"1994","journal-title":"Gut"},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0235","doi-asserted-by":"crossref","first-page":"551","DOI":"10.3390\/ph4030551","article-title":"Carvedilol attenuates inflammatory-mediated cardiotoxicity in Daunorubicin-induced rats","volume":"4","author":"Sari","year":"2011","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.intimp.2017.07.004_bb0240","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4172\/2155-6148.1000130","article-title":"The antioxidative property of nitroglycerin enhances Lornoxicam's antiinflammatory effect","volume":"2","author":"Sen","year":"2011","journal-title":"J Anesth. Clinic Res."},{"issue":"4","key":"10.1016\/j.intimp.2017.07.004_bb0245","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S1043661802001500","article-title":"Gastroprotective effect of \u03b23 adrenoceptor agonists ZD 7114 and CGP 12177A in rats","volume":"46","author":"Sevak","year":"2002","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0250","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.fct.2009.09.015","article-title":"Studies on anti-inflammatory, antipyretic and analgesic properties of Caesalpinia bonducella F. seed oil in experimental animal models","volume":"48","author":"Shukla","year":"2010","journal-title":"Food Chem. Toxicol."},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0255","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0378-8741(98)00175-5","article-title":"Anti-inflammatory effect of the aqueous extract from Rumex patientia L. roots","volume":"65","author":"Suleyman","year":"1991","journal-title":"J. Ethnopharmacol."},{"issue":"7","key":"10.1016\/j.intimp.2017.07.004_bb0260","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1166\/asem.2016.1886","article-title":"Formulation and evaluation of carvedilol loaded lactide nanoparticles: an appraisal to anti-hypertensive and anti-inflammatory therapy","volume":"8","author":"Sunitha","year":"2016","journal-title":"Adv. Sci. Eng. Med."},{"issue":"36","key":"10.1016\/j.intimp.2017.07.004_bb0265","doi-asserted-by":"crossref","first-page":"5798","DOI":"10.3748\/wjg.v12.i36.5798","article-title":"Bromophenacyl bromide, a phospholipase A2 inhibitor attenuates chemically induced gastroduodenal ulcers in rats","volume":"12","author":"Tariq","year":"2006","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.intimp.2017.07.004_bb0270","first-page":"1","article-title":"The role of Lornoxicam in pain and inflammation: a review","volume":"1","author":"Tayal","year":"2012","journal-title":"Curr. Res. Pharm. Sci."},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0275","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.phrs.2006.05.004","article-title":"Protective effect of carvedilol on oxidative stress induced by okadaic acid in N1E-115 cells","volume":"54","author":"Tunez","year":"2006","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0280","first-page":"26","article-title":"Stability study and in-vivo evaluation of lornoxicam loaded ethyl cellulose microspheres","volume":"6","author":"Tyagi","year":"2014","journal-title":"Int. J. Pharma. Sci. Drug Res."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0285","first-page":"147","article-title":"How do NSAIDs cause ulcer disease?","volume":"14","author":"Wallace","year":"2000","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.intimp.2017.07.004_bb0295","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.gene.2014.06.003","article-title":"Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis","volume":"547","author":"Wang","year":"2014","journal-title":"Gene"},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0300","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/S0008-6363(03)00459-0","article-title":"Carvedilol, a new antioxidative beta-blocker, blocks in vitro human peripheral blood T cell activation by downregulating NF-kappaB activity","volume":"59","author":"Yang","year":"2003","journal-title":"Cardiovasc. Res."},{"issue":"6","key":"10.1016\/j.intimp.2017.07.004_bb0305","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/nm.1968","article-title":"Prostaglandin E(2)-EP4 signaling promotes immune inflammation through T(H)1 cell differentiation and T(H)17 cell expansion","volume":"15","author":"Yao","year":"2009","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.intimp.2017.07.004_bb0310","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1097\/FJC.0b013e31815c6624","article-title":"Protective effects of carvedilol in murine model with the coxsackievirus B3-induced viral myocarditis","volume":"51","author":"Yue-Chun","year":"2008","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"6","key":"10.1016\/j.intimp.2017.07.004_bb0315","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0039394","article-title":"Comparison of effects of ivabradine versus carvedilol in murine model with the coxsackievirus B3-induced viral myocarditis","volume":"7","author":"Yue-Chun","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.intimp.2017.07.004_bb0320","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1124\/jpet.104.071548","article-title":"Prostaglandin receptors EP2, EP3, and IP mediate exudate formation in carrageenin-induced mouse pleurisy","volume":"311","author":"Yuhki","year":"2004","journal-title":"J. Pharmacol. Exp. Ther."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576917302709?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576917302709?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T17:10:24Z","timestamp":1761585024000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576917302709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":63,"alternative-id":["S1567576917302709"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2017.07.004","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Carvedilol can attenuate histamine-induced paw edema and formaldehyde-induced arthritis in rats without risk of gastric irritation","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2017.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}