{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:13:01Z","timestamp":1783631581934,"version":"3.55.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81360083"],"award-info":[{"award-number":["81360083"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81401964"],"award-info":[{"award-number":["81401964"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010857","name":"Jiangxi Provincial Department of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010857","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.intimp.2018.07.007","type":"journal-article","created":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T14:00:54Z","timestamp":1532354454000},"page":"293-298","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":87,"special_numbering":"C","title":["Two new inflammatory markers associated with disease activity score-28 in patients with rheumatoid arthritis: Albumin to fibrinogen ratio and C-reactive protein to albumin ratio"],"prefix":"10.1016","volume":"62","author":[{"given":"Wei-ming","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-heng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hou-qun","family":"Ying","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-mei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-hua","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan-juan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8658-1931","authenticated-orcid":false,"given":"Xiao-zhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"23","key":"10.1016\/j.intimp.2018.07.007_bb0005","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1056\/NEJMra1004965","article-title":"The pathogenesis of rheumatoid arthritis","volume":"365","author":"McInnes","year":"2011","journal-title":"N. Engl. J. Med."},{"issue":"2","key":"10.1016\/j.intimp.2018.07.007_bb0010","first-page":"158","article-title":"Rheumatoid arthritis associated interstitial lung disease: a review","volume":"74","author":"Assayag","year":"2014","journal-title":"Medicina"},{"issue":"5","key":"10.1016\/j.intimp.2018.07.007_bb0015","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1002\/art.24433","article-title":"Rheumatoid arthritis joint progression in sustained remission is determined by disease activity levels preceding the period of radiographic assessment","volume":"60","author":"Aletaha","year":"2009","journal-title":"Arthritis Rheum."},{"issue":"7","key":"10.1016\/j.intimp.2018.07.007_bb0020","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/1756-185X.12582","article-title":"Two new inflammatory markers associated with disease activity score-28 in patients with rheumatoid arthritis: neutrophil-lymphocyte ratio and platelet-lymphocyte ratio","volume":"18","author":"Uslu","year":"2015","journal-title":"Int. J. Rheum. Dis."},{"key":"10.1016\/j.intimp.2018.07.007_bb0025","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1471-2474-10-41","article-title":"Disease activity level, remission and response in established rheumatoid arthritis: performance of various criteria sets in an observational cohort, treated with anti-TNF agents","volume":"10","author":"Gulfe","year":"2009","journal-title":"BMC Musculoskelet. Disord."},{"issue":"2","key":"10.1016\/j.intimp.2018.07.007_bb0030","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/01.SMJ.0000153572.22346.E9","article-title":"Laboratory testing in the rheumatic diseases: a practical review","volume":"98","author":"Colglazier","year":"2005","journal-title":"South. Med. J."},{"issue":"5","key":"10.1016\/j.intimp.2018.07.007_bb0035","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1002\/jcla.21908","article-title":"The association between neutrophil\/lymphocyte ratio and disease activity in rheumatoid arthritis and ankylosing spondylitis","volume":"30","author":"Mercan","year":"2016","journal-title":"J. Clin. Lab. Anal."},{"issue":"2","key":"10.1016\/j.intimp.2018.07.007_bb0040","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1098-3597(99)90011-X","article-title":"The role of the laboratory in the evaluation of rheumatic diseases","volume":"2","author":"Kavanaugh","year":"1999","journal-title":"Clin. Cornerstone"},{"issue":"17","key":"10.1016\/j.intimp.2018.07.007_bb0045","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1056\/NEJM199904293401723","volume":"340","year":"1999","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.intimp.2018.07.007_bb0050","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1589\/jpts.27.1137","article-title":"Association between mean platelet volume and bone mineral density in patients with ankylosing spondylitis and diagnostic value of diffusion-weighted magnetic resonance imaging","volume":"27","author":"Resorlu","year":"2015","journal-title":"J. Phys. Ther. Sci."},{"issue":"12","key":"10.1016\/j.intimp.2018.07.007_bb0055","first-page":"5289","article-title":"Red blood cell distribution width: a potential maker estimating disease activity of ankylosing spondylitis","volume":"7","author":"Peng","year":"2014","journal-title":"Int. J. Clin. Exp. Med."},{"issue":"12","key":"10.1016\/j.intimp.2018.07.007_bb0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167967","article-title":"The C-reactive protein to albumin ratio as a predictor of severe side effects of adjuvant chemotherapy in stage III colorectal cancer patients","volume":"11","author":"Tominaga","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.intimp.2018.07.007_bb0065","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1245\/s10434-015-4948-7","article-title":"Clinical significance of the C-reactive protein to albumin ratio for survival after surgery for colorectal cancer","volume":"23","author":"Ishizuka","year":"2016","journal-title":"Ann. Surg. Oncol."},{"issue":"3","key":"10.1016\/j.intimp.2018.07.007_bb0070","first-page":"364","article-title":"Hypercoagulable state is associated with NF-kappa B activation and increased inflammatory factors in patients with rheumatoid arthritis","volume":"32","author":"Zhang","year":"2016","journal-title":"Xi bao yu fen zi mian yi xue za zhi"},{"issue":"2","key":"10.1016\/j.intimp.2018.07.007_bb0075","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s12011-015-0501-6","article-title":"Serum trace element concentrations in rheumatoid arthritis","volume":"171","author":"Sahebari","year":"2016","journal-title":"Biol. Trace Elem. Res."},{"issue":"9","key":"10.1016\/j.intimp.2018.07.007_bb0080","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1136\/ard.2010.138461","article-title":"Hawker, 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative","volume":"69","author":"Aletaha","year":"2010","journal-title":"Ann. Rheum. Dis."},{"issue":"1","key":"10.1016\/j.intimp.2018.07.007_bb0085","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/art.1780380107","article-title":"Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis","volume":"38","author":"Prevoo","year":"1995","journal-title":"Arthritis Rheum."},{"issue":"5965","key":"10.1016\/j.intimp.2018.07.007_bb0090","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1126\/science.1181928","article-title":"Platelets amplify inflammation in arthritis via collagen-dependent microparticle production","volume":"327","author":"Boilard","year":"2010","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.intimp.2018.07.007_bb0095","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s00281-013-0374-8","article-title":"Neutrophils in innate and adaptive immunity","volume":"35","author":"Jaillon","year":"2013","journal-title":"Semin. Immunopathol."},{"issue":"1","key":"10.1016\/j.intimp.2018.07.007_bb0100","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1476-9255-8-30","article-title":"Initiation but no execution - modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis - a potential role for heat shock protein 70","volume":"8","author":"Moodley","year":"2011","journal-title":"J. Inflamm."},{"key":"10.1016\/j.intimp.2018.07.007_bb0105","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.cca.2016.12.007","article-title":"Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio are 2 new inflammatory markers associated with pulmonary involvement and disease activity in patients with dermatomyositis","volume":"465","author":"Yang","year":"2017","journal-title":"Clin. Chim. Acta Int. J. Clin. Chem."},{"key":"10.1016\/j.intimp.2018.07.007_bb0110","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.intimp.2016.04.006","article-title":"Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were associated with disease activity in patients with systemic lupus erythematosus","volume":"36","author":"Wu","year":"2016","journal-title":"Int. Immunopharmacol."},{"issue":"3","key":"10.1016\/j.intimp.2018.07.007_bb0115","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3109\/14397595.2015.1091136","article-title":"Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) were useful markers in assessment of inflammatory response and disease activity in SLE patients","volume":"26","author":"Qin","year":"2016","journal-title":"Mod. Rheumatol."},{"issue":"3\u20134","key":"10.1016\/j.intimp.2018.07.007_bb0120","first-page":"269","article-title":"Neutrophil- and platelet-to-lymphocyte ratios are correlated with disease activity in rheumatoid arthritis","volume":"61","author":"Fu","year":"2015","journal-title":"Clin. Lab."},{"issue":"2","key":"10.1016\/j.intimp.2018.07.007_bb0125","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1207\/S15327914NC352_2","article-title":"Changes in nutritional, functional, and inflammatory markers in advanced pancreatic cancer","volume":"35","author":"Barber","year":"1999","journal-title":"Nutr. Cancer"},{"issue":"3","key":"10.1016\/j.intimp.2018.07.007_bb0130","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1245\/s10434-014-4048-0","article-title":"The C-reactive protein\/albumin ratio, a novel inflammation-based prognostic score, predicts outcomes in patients with hepatocellular carcinoma","volume":"22","author":"Kinoshita","year":"2015","journal-title":"Ann. Surg. Oncol."},{"issue":"7","key":"10.1016\/j.intimp.2018.07.007_bb0135","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1007\/s11605-009-0904-9","article-title":"Changes in inflammatory biomarkers across weight classes in a representative US population: a link between obesity and inflammation","volume":"13","author":"Nguyen","year":"2009","journal-title":"J. Gastrointest. Surg."},{"issue":"5","key":"10.1016\/j.intimp.2018.07.007_bb0140","doi-asserted-by":"crossref","first-page":"382","DOI":"10.3109\/09537104.2013.827782","article-title":"The pretreatment platelet and plasma fibrinogen level correlate with tumor progression and metastasis in patients with pancreatic cancer","volume":"25","author":"Wang","year":"2014","journal-title":"Platelets"},{"issue":"3","key":"10.1016\/j.intimp.2018.07.007_bb0145","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.1007\/s13277-015-4184-6","article-title":"Hyperfibrinogenemia predicts poor prognosis in patients with advanced biliary tract cancer","volume":"37","author":"Li","year":"2016","journal-title":"Tumour Biol. J. Int. Soc. Oncodevelop. Biol. Med."},{"key":"10.1016\/j.intimp.2018.07.007_bb0150","doi-asserted-by":"crossref","DOI":"10.1177\/2333721415591680","article-title":"Interrelationships of sex, physician-diagnosed arthritis, chronic inflammation, and physical functioning in the third National Health and Nutrition Examination Surveys","volume":"1","author":"Beydoun","year":"2015","journal-title":"Gerontol. Geriatr. Med."},{"issue":"6","key":"10.1016\/j.intimp.2018.07.007_bb0155","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.3349\/ymj.2016.57.6.1361","article-title":"Hypoalbuminemia, low base excess values, and tachypnea predict 28-day mortality in severe sepsis and septic shock patients in the emergency department","volume":"57","author":"Seo","year":"2016","journal-title":"Yonsei Med. J."},{"issue":"6","key":"10.1016\/j.intimp.2018.07.007_bb0160","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.7150\/jca.16491","article-title":"A novel blood tool of cancer prognosis in esophageal squamous cell carcinoma: the fibrinogen\/albumin ratio","volume":"8","author":"Tan","year":"2017","journal-title":"J. Cancer"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576918303333?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576918303333?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T17:08:36Z","timestamp":1761584916000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576918303333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":32,"alternative-id":["S1567576918303333"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2018.07.007","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Two new inflammatory markers associated with disease activity score-28 in patients with rheumatoid arthritis: Albumin to fibrinogen ratio and C-reactive protein to albumin ratio","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2018.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}