{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:13:27Z","timestamp":1791810807044,"version":"4.3.4"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002657","name":"Istanbul University","doi-asserted-by":"publisher","award":["T-11\/15122006"],"award-info":[{"award-number":["T-11\/15122006"]}],"id":[{"id":"10.13039\/501100002657","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.intimp.2018.08.017","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T14:48:18Z","timestamp":1535035698000},"page":"52-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["4-Methylcatechol prevents streptozotocin-induced acute kidney injury through modulating NGF\/TrkA and ROS-related Akt\/GSK3\u03b2\/\u03b2-catenin pathways"],"prefix":"10.1016","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1378-1585","authenticated-orcid":false,"given":"Selda","family":"Gezginci-Oktayoglu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ediz","family":"Coskun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merve","family":"Ercin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sehnaz","family":"Bolkent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2018.08.017_bb0005","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/S0140-6736(11)61454-2","article-title":"Acute kidney injury","volume":"380","author":"Bellomo","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.intimp.2018.08.017_bb0010","doi-asserted-by":"crossref","first-page":"F461","DOI":"10.1152\/ajprenal.90735.2008","article-title":"Reactive oxygen species\/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice","volume":"297","author":"Kim","year":"2009","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0015","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.1017\/S1462399409001057","article-title":"Transcription factors in the pathogenesis of diabetic nephropathy","volume":"11","author":"Sanchez","year":"2009","journal-title":"Expert Rev. Mol. Med."},{"key":"10.1016\/j.intimp.2018.08.017_bb0020","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.bbrc.2009.11.019","article-title":"URG11 mediates hypoxia-induced epithelial-tomesenchymal transition by modulation of E-cadherin and b-catenin","volume":"391","author":"Du","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.intimp.2018.08.017_bb0025","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1152\/ajpcell.00141.2011","article-title":"IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells","volume":"302","author":"New","year":"2012","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.intimp.2018.08.017_bb0030","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1038\/ki.2010.516","article-title":"Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases","volume":"79","author":"Barnes","year":"2011","journal-title":"Kidney Int."},{"key":"10.1016\/j.intimp.2018.08.017_bb0035","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1582-4934.2005.tb00337.x","article-title":"The activation of Akt\/PKB signaling pathway and cell survival","volume":"9","author":"Song","year":"2005","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.intimp.2018.08.017_bb0040","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1113\/jphysiol.2006.116715","article-title":"Akt signalling through GSK-3, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy","volume":"576","author":"L\u00e9ger","year":"2006","journal-title":"J. Physiol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0045","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1111\/j.1471-4159.2004.02422.x","article-title":"Glycogen synthase kinase 3: a drug target for CNS therapies","volume":"89","author":"Bhat","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.intimp.2018.08.017_bb0050","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1007\/s12272-009-2200-3","article-title":"Wnt\/b-catenin signaling: a novel target for therapeutic intervention of fibrotic kidney disease","volume":"32","author":"Hwang","year":"2009","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.intimp.2018.08.017_bb0055","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1126\/science.3306916","article-title":"The nerve growth factor 35\u202fyears later","volume":"237","author":"Levi-Montalcini","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.intimp.2018.08.017_bb0060","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1146\/annurev.neuro.24.1.1217","article-title":"Nerve growth factor signaling, neuroprotection, and neural repair","volume":"24","author":"Sofroniew","year":"2001","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.intimp.2018.08.017_bb0065","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.pharmthera.2007.07.003","article-title":"The nerve growth factor and its receptors in airway inflammatory diseases","volume":"117","author":"Freund-Michel","year":"2008","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.intimp.2018.08.017_bb0070","doi-asserted-by":"crossref","first-page":"798","DOI":"10.5301\/JN.2011.6418","article-title":"Altered expression of NGF and its receptors in the kidney of diabetic rats","volume":"24","author":"Aloe","year":"2011","journal-title":"J. Nephrol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0075","first-page":"703","article-title":"Nerve growth factor receptor expression in fetal, mature and diseased human kidneys","volume":"69","author":"Alpers","year":"1993","journal-title":"Lab. Investig."},{"key":"10.1016\/j.intimp.2018.08.017_bb0080","doi-asserted-by":"crossref","first-page":"6162","DOI":"10.1073\/pnas.101130898","article-title":"Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair","volume":"98","author":"Micera","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.intimp.2018.08.017_bb0085","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1023\/A:1018940732550","article-title":"Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector mediated peptide drug delivery","volume":"11","author":"Pardridge","year":"1994","journal-title":"Pharm. Res."},{"key":"10.1016\/j.intimp.2018.08.017_bb0090","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1007\/s10571-011-9782-2","article-title":"Intracerebroventricular 4-methylcatechol (4-MC) ameliorates chronic pain associated with depression-like behavior via induction of brain-derived neurotrophic factor (BDNF)","volume":"32","author":"Fukuhara","year":"2012","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0095","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.npep.2011.01.001","article-title":"4-Methlycatechol prevents NGF\/p75(NTR)-mediated apoptosis via NGF\/TrkA system in pancreatic \u03b2 cells","volume":"45","author":"Gezginci-Oktayoglu","year":"2011","journal-title":"Neuropeptides"},{"key":"10.1016\/j.intimp.2018.08.017_bb0100","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0014-5793(89)81391-2","article-title":"Catecholamines increase nerve growth factor mRNA contents in both mouse astroglial cells and fibroblast cells","volume":"247","author":"Furukawa","year":"1987","journal-title":"FEBS Lett."},{"key":"10.1016\/j.intimp.2018.08.017_bb0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/and.12581","article-title":"4-Methylcatechol inhibits cell growth and testosterone production in TM3 Leydig cells by reducing mitochondrial activity","volume":"49","author":"Li","year":"2017","journal-title":"Andrologia"},{"key":"10.1016\/j.intimp.2018.08.017_bb0110","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s11010-007-9636-x","article-title":"Effects of Z-FA.FMK on d-galactosamine\/tumor necrosis factor-alpha-induced kidney injury and oxidative stress in mice","volume":"309","author":"Gezginci-Oktayoglu","year":"2008","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.intimp.2018.08.017_bb0115","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/0197-0186(90)90025-O","article-title":"Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes","volume":"17","author":"Lebel","year":"1990","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.intimp.2018.08.017_bb0120","first-page":"123","article-title":"Influence of age, exercise, and dietary restriction on oxidative stress in rats","volume":"8","author":"Kim","year":"1996","journal-title":"Aging (Milano)"},{"key":"10.1016\/j.intimp.2018.08.017_bb0125","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1046\/j.1523-1755.2002.00433.x","article-title":"Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury","volume":"62","author":"Han","year":"2002","journal-title":"Kidney Int."},{"key":"10.1016\/j.intimp.2018.08.017_bb0130","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s10495-011-0657-2","article-title":"Ras signaling in NGF reduction and TNF-\u03b1-related pancreatic \u03b2 cell apoptosis in hyperglycemic rats","volume":"17","author":"Gezginci-Oktayoglu","year":"2012","journal-title":"Apoptosis"},{"key":"10.1016\/j.intimp.2018.08.017_bb0135","doi-asserted-by":"crossref","first-page":"27200","DOI":"10.1074\/jbc.M113.469486","article-title":"Phlorizin pretreatment reduces acute renal toxicity in a mouse model for diabetic nephropathy","volume":"288","author":"Brouwers","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2018.08.017_bb0140","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/s00125-007-0886-7","article-title":"The mechanisms of alloxan and streptozotocin-induced diabetes","volume":"51","author":"Lenzen","year":"2008","journal-title":"Diabetologia"},{"key":"10.1016\/j.intimp.2018.08.017_bb0145","doi-asserted-by":"crossref","first-page":"C1033","DOI":"10.1152\/ajpcell.00338.2006","article-title":"Streptozotocin induces G2 arrest in skeletal muscle myoblasts and impairs muscle growth in vivo","volume":"292","author":"Johnston","year":"2007","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.intimp.2018.08.017_bb0150","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.bbrc.2004.04.138","article-title":"Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes via a p38 map kinase-dependent oxidative stress mechanism","volume":"318","author":"Wold","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.intimp.2018.08.017_bb0155","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1681\/ASN.2009070721","article-title":"Mouse models of diabetic nephropathy","volume":"20","author":"Brosius","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0160","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1440-1797.2007.00796.x","article-title":"Rodent models of streptozotocin induced diabetic nephropathy","volume":"12","author":"Tesch","year":"2007","journal-title":"Nephrology (Carlton)"},{"key":"10.1016\/j.intimp.2018.08.017_bb0165","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/jnr.10431","article-title":"4-Methylcatechol stimulates phosphorylation of Trk family neurotrophin receptors and MAP kinases in cultured rat cortical neurons","volume":"70","author":"Sometani","year":"2002","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.intimp.2018.08.017_bb0170","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/ar.a.10010","article-title":"p75NTR in the spleen: age-dependent changes, effect of NGF and 4-methylcatechol treatment, and structural changes in p75NTR-deficient mice","volume":"270","author":"P\u00e9rez-P\u00e9rez","year":"2003","journal-title":"Anat. Rec. A: Discov. Mol. Cell. Evol. Biol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0175","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3109\/08977194.2015.1054989","article-title":"Nerve growth factor exposure promotes tubular epithelial-mesenchymal transition via TGF-\u03b21 signaling activation","volume":"33","author":"Vizza","year":"2015","journal-title":"Growth Factors"},{"key":"10.1016\/j.intimp.2018.08.017_bb0180","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1016\/j.transproceed.2013.07.020","article-title":"High nerve growth factor blood concentration in renal transplantation: a new prognostic marker?","volume":"45","author":"Gigliotti","year":"2013","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.intimp.2018.08.017_bb0185","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3109\/08977194.2014.975799","article-title":"Human kidney podocyte cell population as a novel biological target of nerve growth factor","volume":"33","author":"Caroleo","year":"2015","journal-title":"Growth Factors"},{"key":"10.1016\/j.intimp.2018.08.017_bb0190","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.2337\/db11-1138","article-title":"Hyperglycemia causes renal cell damage via CCN2-induced activation of the TrkA receptor: implications for diabetic nephropathy","volume":"61","author":"Fragiadaki","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.intimp.2018.08.017_bb0195","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1161\/CIRCRESAHA.110.223545","article-title":"Oxidative stress and diabetic complications","volume":"107","author":"Giacco","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.intimp.2018.08.017_bb0200","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s12291-008-0003-9","article-title":"Alcohol induced effects on kidney","volume":"23","author":"Das Kumar","year":"2008","journal-title":"Indian J. Clin. Biochem."},{"key":"10.1016\/j.intimp.2018.08.017_bb0205","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1124\/jpet.103.050351","article-title":"In vitro cytotoxicity of 4-methylcatechol in murine tumor cells: induction of apoptotic cell death by extracellular pro-oxidant action","volume":"306","author":"Morita","year":"2003","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.intimp.2018.08.017_bb0210","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1002\/jcb.26367","article-title":"Necrotic cell death occur via JNK pathway with the activity of transcription factor c-Jun by 4-MC in INS-1 cell line","volume":"119","author":"Karatug Kacar","year":"2018","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.intimp.2018.08.017_bb0215","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1042\/BSR20130066","article-title":"How does the metabolism of tumour cells differ from that of normal cells","volume":"33","author":"Amo\u00eado","year":"2013","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.intimp.2018.08.017_bb0220","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/sj.ki.5000054","article-title":"Renal fibrosis: new insights into the pathogenesis and therapeutics","volume":"69","author":"Liu","year":"2006","journal-title":"Kidney Int."},{"key":"10.1016\/j.intimp.2018.08.017_bb0225","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.freeradbiomed.2010.01.006","article-title":"Linking oxidative stress to inflammation: toll-like receptors","volume":"48","author":"Gill","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2018.08.017_bb0230","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1172\/JCI118498","article-title":"Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury","volume":"97","author":"Kelly","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.intimp.2018.08.017_bb0235","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1681\/ASN.V111152","article-title":"Chemokines, chemokine receptors, and renal disease: from basic science to pathophysiologic and therapeutic studies","volume":"11","author":"Segerer","year":"2000","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0240","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1111\/j.1523-1755.2002.kid577.x","article-title":"Enhanced MCP-1 expression during ischemia\/reperfusion injury is mediated by oxidative stress and NF-kappaB","volume":"62","author":"Sung","year":"2002","journal-title":"Kidney Int."},{"key":"10.1016\/j.intimp.2018.08.017_bb0245","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/ki.1990.44","article-title":"Interleukin 1-alpha and tumor necrosis factor-alpha induce oxygen radical production in mesangial cells","volume":"37","author":"Raedke","year":"1990","journal-title":"Kidney Int."},{"key":"10.1016\/j.intimp.2018.08.017_bb0250","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1002\/cphy.c120028","article-title":"Immune and inflammatory role in renal disease","volume":"3","author":"Imig","year":"2013","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0255","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/sj.bjp.0704866","article-title":"Production of inflammatory mediators by renal epithelial cells is insensitive to glucocorticoids","volume":"137","author":"de Haij","year":"2002","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0260","doi-asserted-by":"crossref","first-page":"22699","DOI":"10.1074\/jbc.274.32.22699","article-title":"Reactive oxygen species mediate the activation of Akt\/protein kinase B by angiotensin II in vascular smooth muscle cells","volume":"274","author":"Ushio-Fukai","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2018.08.017_bb0265","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1440-1797.2006.00558.x","article-title":"Role of PI3-kinase\/Akt signalling pathway in renal function and cell proliferation after renal ischaemia\/reperfusion injury in mice","volume":"11","author":"Xie","year":"2006","journal-title":"Nephrology (Carlton)"},{"key":"10.1016\/j.intimp.2018.08.017_bb0270","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000443414","article-title":"Protective effect of tempol on acute kidney injury through PI3K\/Akt\/Nrf2 signaling pathway","volume":"41","author":"Zhang","year":"2016","journal-title":"Kidney Blood Press. Res."},{"key":"10.1016\/j.intimp.2018.08.017_bb0275","article-title":"Antiangiogenic treatment diminishes renal injury and dysfunction via regulation of local AKT in early experimental diabetes","volume":"9","author":"Bai","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2018.08.017_bb0280","doi-asserted-by":"crossref","first-page":"307","DOI":"10.5527\/wjn.v4.i2.307","article-title":"Species differences in regulation of renal proximal tubule transport by certain molecules","volume":"4","author":"Seki","year":"2015","journal-title":"World J. Nephrol."},{"key":"10.1016\/j.intimp.2018.08.017_bb0285","first-page":"2038","article-title":"Catalpol protects mice against renal ischemia\/reperfusion injury via suppressing PI3K\/Akt-eNOS signaling and inflammation","volume":"8","author":"Zhu","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.intimp.2018.08.017_bb0290","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/nep.12384","article-title":"Erythropoietin pretreatment ameliorates renal ischaemia-reperfusion injury by activating PI3K\/Akt signalling","volume":"20","author":"Zhang","year":"2015","journal-title":"Nephrology (Carlton)"},{"key":"10.1016\/j.intimp.2018.08.017_bb0295","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1038\/ki.2012.239","article-title":"Specific deletion of glycogen synthase kinase-3\u03b2 in the renal proximal tubule protects against acute nephrotoxic injury in mice","volume":"82","author":"Howard","year":"2012","journal-title":"Kidney Int."},{"key":"10.1016\/j.intimp.2018.08.017_bb0300","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/ki.2012.173","article-title":"Tubule-specific ablation of endogenous \u03b2-catenin aggravates acute kidney injury in mice","volume":"82","author":"Zhou","year":"2012","journal-title":"Kidney Int."},{"key":"10.1016\/j.intimp.2018.08.017_bb0305","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.3892\/mmr.2014.2650","article-title":"Inhibition of glycogen synthase kinase-3\u03b2 attenuates acute kidney injury in sodium taurocholate-induced severe acute pancreatitis in rats","volume":"10","author":"Zhao","year":"2014","journal-title":"Mol. Med. Rep."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576918304120?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576918304120?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T23:49:19Z","timestamp":1661816959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576918304120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":61,"alternative-id":["S1567576918304120"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2018.08.017","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"4-Methylcatechol prevents streptozotocin-induced acute kidney injury through modulating NGF\/TrkA and ROS-related Akt\/GSK3\u03b2\/\u03b2-catenin pathways","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2018.08.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}